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List of works by Young Whang

A multidisciplinary approach to the management of urologic malignancies: does it influence diagnostic and treatment decisions?

scientific article published on 03 July 2009

A phase 1 study of a chimeric monoclonal antibody against interleukin-6, siltuximab, combined with docetaxel in patients with metastatic castration-resistant prostate cancer.

scientific article published on 25 July 2012

A phase 2 study of estramustine, docetaxel, and bevacizumab in men with castrate-resistant prostate cancer: results from Cancer and Leukemia Group B Study 90006.

scientific article

A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: clinical and pathological results.

scientific article published on 19 January 2010

Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation

scientific article

Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox

scientific article

Androgen Receptor-Dependent and -Independent Mechanisms Involved in Prostate Cancer Therapy Resistance.

scientific article

Androgen receptor targeting drugs in castration-resistant prostate cancer and mechanisms of resistance

scientific article

Application of liquid biopsies to identify genomic factors associated with therapy resistance in castration resistant prostate cancer.

scientific article published on October 2016

Arrays of High-Aspect Ratio Microchannels for High-Throughput Isolation of Circulating Tumor Cells (CTCs).

scientific article published in October 2014

Cabozantinib-induced serum creatine kinase elevation and musculoskeletal complaints

scientific article published on 28 June 2018

Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer

scientific article published on 01 May 2021

Cutaneous adverse reactions in B-RAF positive metastatic melanoma following sequential treatment with B-RAF/MEK inhibitors and immune checkpoint blockade or vice versa. A single-institutional case-series

scientific article published on 08 January 2019

Dacomitinib, but not lapatinib, suppressed progression in castration-resistant prostate cancer models by preventing HER2 increase

scientific article published on 18 June 2019

Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases

scientific article

Functional role for the c-Abl tyrosine kinase in meiosis I

scientific journal article

Genomic Profiling of Cancers of Unknown Primary Site: The Next Steps

scientific article published on 01 July 2015

Germline Genetic Testing in Advanced Prostate Cancer; Practices and Barriers: Survey Results from the Germline Genetics Working Group of the Prostate Cancer Clinical Trials Consortium

scientific article published on 18 April 2019

Heregulin-induced activation of HER2 and HER3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth.

scientific article published on March 2005

Identification of a pseudogene that can masquerade as a mutant allele of the PTEN/MMAC1 tumor suppressor gene.

scientific article published in June 1998

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression ⬇️

scientific article published on April 28, 1998

Inhibition of HER-2/neu kinase impairs androgen receptor recruitment to the androgen responsive enhancer.

scientific article

Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen

scientific article published on 09 December 2019

Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability

scientific article (publication date: September 2006)

Mechanisms of acquired resistance to androgen receptor targeting drugs in castration-resistant prostate cancer.

scientific article published on 13 June 2014

Mutation of androgen receptor N-terminal phosphorylation site Tyr-267 leads to inhibition of nuclear translocation and DNA binding

scientific article published on 7 May 2015

Neoadjuvant chemotherapy administration and time to cystectomy for muscle-invasive bladder cancer: An evaluation of transitions between academic and community settings

scientific article published on 26 June 2015

Neoadjuvant docetaxel/estramustine prior to radical prostatectomy or external beam radiotherapy in high risk localized prostate cancer: a phase II trial

scientific article published on 21 December 2009

PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway.

scientific article published on January 2002

Phase I study of concurrent weekly docetaxel, high-dose intensity-modulated radiation therapy (IMRT) and androgen-deprivation therapy (ADT) for high-risk prostate cancer

scientific article published on 27 September 2012

Phase II trial of palbociclib in patients with metastatic urothelial cancer after failure of first-line chemotherapy

scientific article published on 08 October 2018

Posterior reversible encephalopathy syndrome induced by enzalutamide in a patient with castration-resistant prostate cancer.

scientific article

Practical Considerations and Challenges for Germline Genetic Testing in Patients With Prostate Cancer: Recommendations From the Germline Genetics Working Group of the PCCTC

scientific article published on 28 September 2020

Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: a search for biomarkers of sensitivity to treatment.

scientific article

Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest.

scientific article published on 24 October 2005

Regulation of sensitivity to TRAIL by the PTEN tumor suppressor.

scientific article published on January 2004

Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase

scientific article published on 01 May 2000

Renal cell carcinoma

scientific article published on 01 May 2003

Response to degarelix after resistance to luteinizing hormone-releasing hormone agonist therapy for metastatic prostate cancer

scientific article published on 01 March 2011

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.

scientific article published on July 1996

Signal transduction by wild-type and leukemogenic Abl proteins.

scientific article published on December 1997

Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012.

scientific article published on 20 December 2017

The PTEN tumor suppressor inhibits telomerase activity in endometrial cancer cells by decreasing hTERT mRNA levels.

scientific article published on 27 December 2005

The impact of altered annexin I protein levels on apoptosis and signal transduction pathways in prostate cancer cells.

scientific article published on September 2006

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer

scientific article published on 27 September 2018

Zinc-induced PTEN protein degradation through the proteasome pathway in human airway epithelial cells.

scientific article published on 12 May 2003

c-Abl is required for development and optimal cell proliferation in the context of p53 deficiency

scientific journal article

p38 and EGF receptor kinase-mediated activation of the phosphatidylinositol 3-kinase/Akt pathway is required for Zn2+-induced cyclooxygenase-2 expression.

scientific article published on 24 June 2005

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