List of works - Minna Woo

Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy.

scientific article published on 23 April 2009

Absence of caspase-3 protects pancreatic {beta}-cells from c-Myc-induced apoptosis without leading to tumor formation.

scientific article

Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing

scientific article published on 16 February 2014

Beyond erythropoiesis: emerging metabolic roles of erythropoietin

scientific article

Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T-cell death

scientific article published on 01 December 2010

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

scientific journal article

Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus.

scientific article published on May 2005

DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice.

scientific article published on 16 June 2015

Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide

scientific article published on 01 February 2012

Deletion of Pten in pancreatic ß-cells protects against deficient ß-cell mass and function in mouse models of type 2 diabetes. ⬇️

scientific article published on 17 September 2010

Dichotomous role of pancreatic HUWE1/MULE/ARF-BP1 in modulating beta cell apoptosis in mice under physiological and genotoxic conditions

scientific article published on July 2014

Dietary Curcumin Intervention Targets Mouse White Adipose Tissue Inflammation and Brown Adipose Tissue UCP1 Expression

scientific article published on 6 February 2018

Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.

scientific article published on 6 April 2010

Differential requirement for caspase 9 in apoptotic pathways in vivo.

scientific article published on August 1998

Distinct in vivo roles of caspase-8 in beta-cells in physiological and diabetes models

scientific article published on 11 June 2007

Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth.

scientific article published on 26 July 2012

Erythropoietin and glucose homeostasis in women at varying degrees of future diabetic risk.

scientific article published on 16 September 2014

Erythropoietin protects against diabetes through direct effects on pancreatic β cells ⬇️

scientific article published on December 13, 2010

Essential role of Pten in body size determination and pancreatic beta-cell homeostasis in vivo

scientific article published on June 2006

Excitatory tonus is required for the survival of granule cell precursors during postnatal development within the cerebellum.

scientific article

Extracellular matrix-derived extracellular vesicles promote cardiomyocyte growth and electrical activity in engineered cardiac atria.

scientific article published on 4 September 2017

FAK signalling controls insulin sensitivity through regulation of adipocyte survival.

scientific article published on 06 February 2017

Generation and characterization of Smac/DIABLO-deficient mice.

scientific article

Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.

scientific article

Hepatocyte-specific Deletion of Janus Kinase 2 (JAK2) Protects against Diet-induced Steatohepatitis and Glucose Intolerance ⬇️

scientific article published on January 24, 2012

In Vivo Knockdown of Adipocyte Erythropoietin Receptor Does Not Alter Glucose or Energy Homeostasis ⬇️

scientific article published on July 24, 2013

In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking

scientific article

Inner ear dysfunction in caspase-3 deficient mice ⬇️

scientific article published on October 12, 2011

JAK/STAT - Emerging Players in Metabolism.

scientific article published on 27 November 2017

JAK2 promotes brown adipose tissue function and is required for diet- and cold-induced thermogenesis in mice.

scientific article published on 29 October 2015

Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice.

scientific article published on 18 January 2017

Janus Kinase 2 Regulates Transcription Factor EB Expression and Autophagy Completion in Glomerular Podocytes.

scientific article published on 19 April 2017

Lecithin cholesterol acyltransferase null mice are protected from diet-induced obesity and insulin resistance in a gender-specific manner through multiple pathways.

scientific article

Long-term intake of North American ginseng has no effect on 24-hour blood pressure and renal function

scientific article published on 06 March 2006

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation.

scientific article

Methods for Assessing the In Vivo Role of PTEN in Glucose Homeostasis

scientific article published on January 2016

Mice lacking NOX2 are hyperphagic and store fat preferentially in the liver

scientific article published on 22 April 2014

North American ginseng exerts a neutral effect on blood pressure in individuals with hypertension.

scientific article published on 5 July 2005

Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance.

scientific article published on 29 June 2016

Overexpression of HIF-2α in pancreatic β cells does not alter glucose homeostasis.

scientific article published on January 2014

PTEN deletion and concomitant c-Myc activation do not lead to tumor formation in pancreatic beta cells.

scientific article

PTEN deletion in pancreatic α-cells protects against high-fat diet-induced hyperglucagonemia and insulin resistance.

scientific article

Pancreatic β cells: Gatekeepers of type 2 diabetes

scientific article published on 29 January 2019

Partial deletion of Pten in the hypothalamus leads to growth defects that cannot be rescued by exogenous growth hormone

scientific article published on 22 May 2008

Perforin is a novel immune regulator of obesity-related insulin resistance.

scientific article

Perforin-dependent activation-induced cell death acts through caspase 3 but not through caspases 8 or 9

scientific article published on 01 March 2003

Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice

scientific journal article

Prolactin-stimulated survivin induction is required for beta cell mass expansion during pregnancy in mice

scientific article

Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex.

scientific article published on 20 April 2014

Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action

scientific article published on 24 September 2014

Reduction in new-onset diabetes mellitus after renal transplant with erythropoietin-stimulating agents: a retrospective cohort study

scientific article published on 26 April 2016

Redundant role of the cytochrome c-mediated intrinsic apoptotic pathway in pancreatic β-cells ⬇️

scientific article published on June 30, 2011

Regulation of obesity-related insulin resistance with gut anti-inflammatory agents

scientific article published on April 2015

Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate.

scientific article published on 14 August 2013

SIRT1 activation ameliorates hyperglycaemia by inducing a torpor-like state in an obese mouse model of type 2 diabetes

scientific article published on 7 January 2015

Survivin Is Required for Beta-Cell Mass Expansion in the Pancreatic Duct-Ligated Mouse Model ⬇️

scientific article published on January 1, 2012

The extra-hematopoietic role of erythropoietin in diabetes mellitus.

scientific article published on July 2011

The redundant role of JAK2 in regulating pancreatic β-cell mass.

scientific article published on November 2011

The role of caspase-8 in amyloid-induced beta cell death in human and mouse islets

scientific article published on 19 January 2014

The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis

scientific article published on 01 November 2004

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

scientific article (publication date: 28 June 1996)

Timing is everything: Rb's choice in islet-cell fate

scientific article published on 14 February 2014

ULK1 prevents cardiac dysfunction in obesity through autophagy-meditated regulation of lipid metabolism.

scientific article published on 17 April 2017

Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice

scientific article published on 17 January 2011

List of works by Minna Woo

Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy.

Absence of caspase-3 protects pancreatic {beta}-cells from c-Myc-induced apoptosis without leading to tumor formation.

Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing

Beyond erythropoiesis: emerging metabolic roles of erythropoietin

Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T-cell death

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus.

DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice.

Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide

Deletion of Pten in pancreatic ß-cells protects against deficient ß-cell mass and function in mouse models of type 2 diabetes. ⬇️

Dichotomous role of pancreatic HUWE1/MULE/ARF-BP1 in modulating beta cell apoptosis in mice under physiological and genotoxic conditions

Dietary Curcumin Intervention Targets Mouse White Adipose Tissue Inflammation and Brown Adipose Tissue UCP1 Expression

Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.

Differential requirement for caspase 9 in apoptotic pathways in vivo.

Distinct in vivo roles of caspase-8 in beta-cells in physiological and diabetes models

Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth.

Erythropoietin and glucose homeostasis in women at varying degrees of future diabetic risk.

Erythropoietin protects against diabetes through direct effects on pancreatic β cells ⬇️

Essential role of Pten in body size determination and pancreatic beta-cell homeostasis in vivo

Excitatory tonus is required for the survival of granule cell precursors during postnatal development within the cerebellum.

Extracellular matrix-derived extracellular vesicles promote cardiomyocyte growth and electrical activity in engineered cardiac atria.

FAK signalling controls insulin sensitivity through regulation of adipocyte survival.

Generation and characterization of Smac/DIABLO-deficient mice.

Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.

Hepatocyte-specific Deletion of Janus Kinase 2 (JAK2) Protects against Diet-induced Steatohepatitis and Glucose Intolerance ⬇️

In Vivo Knockdown of Adipocyte Erythropoietin Receptor Does Not Alter Glucose or Energy Homeostasis ⬇️

In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking

Inner ear dysfunction in caspase-3 deficient mice ⬇️

JAK/STAT - Emerging Players in Metabolism.

JAK2 promotes brown adipose tissue function and is required for diet- and cold-induced thermogenesis in mice.

Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice.

Janus Kinase 2 Regulates Transcription Factor EB Expression and Autophagy Completion in Glomerular Podocytes.

Lecithin cholesterol acyltransferase null mice are protected from diet-induced obesity and insulin resistance in a gender-specific manner through multiple pathways.

Long-term intake of North American ginseng has no effect on 24-hour blood pressure and renal function

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation.

Methods for Assessing the In Vivo Role of PTEN in Glucose Homeostasis

Mice lacking NOX2 are hyperphagic and store fat preferentially in the liver

North American ginseng exerts a neutral effect on blood pressure in individuals with hypertension.

Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance.

Overexpression of HIF-2α in pancreatic β cells does not alter glucose homeostasis.

PTEN deletion and concomitant c-Myc activation do not lead to tumor formation in pancreatic beta cells.

PTEN deletion in pancreatic α-cells protects against high-fat diet-induced hyperglucagonemia and insulin resistance.

Pancreatic β cells: Gatekeepers of type 2 diabetes

Partial deletion of Pten in the hypothalamus leads to growth defects that cannot be rescued by exogenous growth hormone

Perforin is a novel immune regulator of obesity-related insulin resistance.

Perforin-dependent activation-induced cell death acts through caspase 3 but not through caspases 8 or 9

Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice

Prolactin-stimulated survivin induction is required for beta cell mass expansion during pregnancy in mice

Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex.

Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action

Reduction in new-onset diabetes mellitus after renal transplant with erythropoietin-stimulating agents: a retrospective cohort study

Redundant role of the cytochrome c-mediated intrinsic apoptotic pathway in pancreatic β-cells ⬇️

Regulation of obesity-related insulin resistance with gut anti-inflammatory agents

Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate.

SIRT1 activation ameliorates hyperglycaemia by inducing a torpor-like state in an obese mouse model of type 2 diabetes

Survivin Is Required for Beta-Cell Mass Expansion in the Pancreatic Duct-Ligated Mouse Model ⬇️

The extra-hematopoietic role of erythropoietin in diabetes mellitus.

The redundant role of JAK2 in regulating pancreatic β-cell mass.

The role of caspase-8 in amyloid-induced beta cell death in human and mouse islets

The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

Timing is everything: Rb's choice in islet-cell fate

ULK1 prevents cardiac dysfunction in obesity through autophagy-meditated regulation of lipid metabolism.

Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice