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List of works by Rosalind Jenkins

A mechanistic investigation into the irreversible protein binding and antigenicity of p-phenylenediamine.

scientific article published in June 2009

A method for the rapid depletion of albumin and immunoglobulin from human plasma.

scientific article

A technically detailed and pragmatic protocol for quantitative serum proteomics using iTRAQ.

scientific article published on 3 August 2009

Albumin and immunoglobulin depletion of human plasma

scientific article published on 01 January 2008

Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics.

scientific article

Arrays for protein expression profiling: Towards a viable alternative to two-dimensional gel electrophoresis? ⬇️

scientific article published on January 1, 2001

Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis

scientific article

Biomarkers distinguish apoptotic and necrotic cell death during hepatic ischemia/reperfusion injury in mice.

scientific article

Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSA in vitro and in vivo.

scientific article published on June 2009

Characterization of Clozapine-Responsive Human T Cells

scientific article published on 28 September 2020

Characterization of Flucloxacillin-specific CD8+ T-cells in a mouse model.

scientific article

Characterization of a bifunctional catalase-peroxidase of Burkholderia cenocepacia.

scientific article published on 16 March 2007

Characterization of a secreted antigen of Onchocerca volvulus with host‐protective potential ⬇️

scientific article published on January 1, 1996

Characterization of anti-drug antibodies and drug-responsive B-lymphocytes in piperacillin hypersensitive patients with cystic fibrosis.

scientific article

Characterization of the Inflammatory Properties of Actively Released HMGB1 in Juvenile Idiopathic Arthritis

scientific article published on 22 December 2014

Cloning of a cuticular antigen that contains multiple tandem repeats from the filarial parasite Dirofilaria immitis ⬇️

scientific article published on July 1, 1992

Confounding effect of obstructive jaundice in the interpretation of proteomic plasma profiling data for pancreatic cancer

scientific article

Cuticular localisation and turnover of the major surface glycoprotein (gp29) of adult Brugia malayi ⬇️

scientific article published on August 1, 1990

Cyclization of the acyl glucuronide metabolite of a neutral endopeptidase inhibitor to an electrophilic glutarimide: synthesis, reactivity, and mechanistic analysis.

scientific article published on 7 November 2007

Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus

scientific article published on 16 November 2015

Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients

scientific article published on 24 April 2017

Detection and biochemical characterisation of a novel polymorphism in the human GSTP1 gene.

scientific article published on 18 May 2007

Detection of drug bioactivation in vivo: mechanism of nevirapine-albumin conjugate formation in patients.

scientific article published on 12 March 2013

Detection of drug-responsive B lymphocytes and antidrug IgG in patients with β-lactam hypersensitivity ⬇️

scientific article published on 15 November 2016

Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes.

scientific article published on 31 August 2005

Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study

scientific article

Glutathione-S-transferase pi as a model protein for the characterisation of chemically reactive metabolites.

scientific article

Glycation of Host Proteins Increases Pathogenic Potential of Porphyromonas gingivalis

scientific article published in 2021

Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study ⬇️

scientific article published on June 12, 2013

Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury.

scientific article

Identification and quantification of the basal and inducible Nrf2-dependent proteomes in mouse liver: biochemical, pharmacological and toxicological implications

scientific article

Increased expression of chemerin in squamous esophageal cancer myofibroblasts and role in recruitment of mesenchymal stromal cells

scientific article

Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney

scientific article

Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer

scientific article published in November 2010

MDM2 interacts with NME2 (non-metastatic cells 2, protein) and suppresses the ability of NME2 to negatively regulate cell motility.

scientific article

Mass spectrometric characterization of circulating covalent protein adducts derived from a drug acyl glucuronide metabolite: multiple albumin adductions in diclofenac patients

scientific article

Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

retracted scientific article

Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics.

scientific article

Network analysis of primary hepatocyte dedifferentiation using a shotgun proteomics approach.

scientific article published in May 2010

Onchocerca volvulus larval antigen, OvB20, induces partial protection in a rodent model of onchocerciasis.

scientific article

Oxidative Bioactivation of Abacavir in Subcellular Fractions of Human Antigen Presenting Cells ⬇️

scientific article published on June 12, 2013

PKC-2 phosphorylation of UNC-18 Ser322 in AFD neurons regulates temperature dependency of locomotion.

scientific article

Pancreatic cancer cells overexpress gelsolin family-capping proteins, which contribute to their cell motility

scientific article published on 17 July 2006

Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes. ⬇️

scientific article

Phosphorylation of cysteine string protein on Serine 10 triggers 14-3-3 protein binding.

scientific article

Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway

scientific article published on 8 April 2010

Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice

scientific article published on 03 October 2013

Protective immunity induced by vaccination with Onchocerca volvulus tropomyosin in rodents ⬇️

scientific article published on May 1, 1996

Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver.

scientific article

Proteomic profiling of murine biliary-derived hepatic organoids and their capacity for drug disposition, bioactivation and detoxification

scientific article published on 29 May 2021

Relative and absolute quantitative expression profiling of cytochromes P450 using isotope-coded affinity tags

scientific article published on 01 March 2006

Release of TGFβig-h3 by gastric myofibroblasts slows tumor growth and is decreased with cancer progression.

scientific article

Safety pharmacology--current and emerging concepts.

scientific article

Smad4 loss is associated with fewer S100A8-positive monocytes in colorectal tumors and attenuated response to S100A8 in colorectal and pancreatic cancer cells.

scientific article

Tetracycline-inducible protein expression in pancreatic cancer cells: effects of CapG overexpression

scientific article

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

scientific article

The expression of S100A8 in pancreatic cancer-associated monocytes is associated with the Smad4 status of pancreatic cancer cells

scientific article

Total proteome analysis identifies migration defects as a major pathogenetic factor in immunoglobulin heavy chain variable region (IGHV)-unmutated chronic lymphocytic leukemia.

scientific article

Tropomyosin implicated in host protective responses to microfilariae in onchocerciasis.

scientific article

Vaccination generates serum-mediated protection against Onchocerca lienalis microfilariae in the mouse.

scientific article published on June 1996

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