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List of works by Zee Upton

3D mesenchymal stem/stromal cell osteogenesis and autocrine signalling.

scientific article

A chimeric vitronectin: IGF-I protein supports feeder-cell-free and serum-free culture of human embryonic stem cells

article

A comparison of methods for classifying clinical samples based on proteomics data: a case study for statistical and machine learning approaches.

scientific article

A fragment of the LG3 peptide of endorepellin is present in the urine of physically active mining workers: a potential marker of physical activity

scientific article (publication date: 2012)

A mathematical model of wound healing and subsequent scarring

scientific article

A peptidomimetic inhibitor of matrix metalloproteinases containing a tetherable linker group

scientific article published on 25 January 2011

A pre-clinical functional assessment of an acellular scaffold intended for the treatment of hard-to-heal wounds

scientific article published on 05 April 2013

A tan in a test tube - in vitro models for investigating ultraviolet radiation-induced damage in skin

scientific article published on 16 April 2012

Adult human articular chondrocytes in a microcarrier-based culture system: expansion and redifferentiation

article

An investigation into the effect of amphiphilic siloxane oligomers on dermal fibroblasts

scientific article published on 12 May 2012

Antagonists of IGF:Vitronectin Interactions Inhibit IGF-I-Induced Breast Cancer Cell Functions

scientific article

Anti-inflammatory effects of shikonin in human periodontal ligament cells

scientific article published on 01 December 2018

Application of "macromolecular crowding" in vitro to investigate the naphthoquinones shikonin, naphthazarin and related analogues for the treatment of dermal scars

scientific article published on 10 July 2019

Arrays of Biocompatible and Mechanically Robust Microchambers Made of Protein-Polyphenol-Clay Multilayer Films

scientific article published on 15 September 2020

Assessment of developmental changes in chicken and turkey insulin-like growth factor-II by homologous radioimmunoassay.

scientific article published on June 1998

Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models

scientific article published on 21 July 2016

Attenuation of protease activity in chronic wound fluid with bisphosphonate-functionalised hydrogels.

scientific article published on 31 January 2008

Bottom-up physiologically-based biokinetic modelling as an alternative to animal testing

scientific article published on 10 May 2019

Characteristics of microbial drug resistance and its correlates in chronic diabetic foot ulcer infections

scientific article

Characterization of a human skin equivalent model to study the effects of ultraviolet B radiation on keratinocytes.

scientific article

Chimeric vitronectin:insulin-like growth factor proteins enhance cell growth and migration through co-activation of receptors

scientific article published on October 2007

Choose wisely: Network, ontology and annotation resources for the analysis of Staphylococcus aureus omics data

scientific article

Clinical and economic burden of wound care in the tropics: a 5-year institutional population health review

scientific article published on 09 March 2020

Comparison of recombinant barramundi and human insulin-like growth factor (IGF)-I in juvenile barramundi (Lates calcarifer): in vivo metabolic effects, association with circulating IGF-binding proteins, and tissue localisation

scientific article published on 01 March 2000

Dermal fibroblast infiltration of poly(ε-caprolactone) scaffolds fabricated by melt electrospinning in a direct writing mode.

scientific article published on 27 February 2013

Development and validation of a radioimmunoassay for fish insulin-like growth factor I (IGF-I) and the effect of aquaculture related stressors on circulating IGF-I levels

scientific article

Development of a three-dimensional human skin equivalent wound model for investigating novel wound healing therapies

scientific article published on 01 October 2010

Development of an enhanced proteomic method to detect prognostic and diagnostic markers of healing in chronic wound fluid

scientific article published on 06 December 2007

Development of defined media for the serum-free expansion of primary keratinocytes and human embryonic stem cells.

scientific article published in September 2008

Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progression

scientific article

Effectiveness of an acellular synthetic matrix in the treatment of hard-to-heal leg ulcers

scientific article published on 9 July 2013

Effects of oxygen and culture system on in vitro propagation and redifferentiation of osteoarthritic human articular chondrocytes ⬇️

scientific article published on June 4, 2011

Effects of oxygen on zonal marker expression in human articular chondrocytes.

scientific article

Elevated uric acid correlates with wound severity

scientific article published on 04 October 2011

Evaluation of haemoglobin in blister fluid as an indicator of paediatric burn wound depth.

scientific article

Evolution of insulin-like growth factor (IGF) function: production and characterization of recombinant hagfish IGF.

scientific article

Evolution of insulin-like growth factor-I (IGF-I) action: in vitro characterization of vertebrate IGF-I proteins

scientific article published on 01 September 1998

Facilitators and barriers of using digital technology for the management of diabetic foot ulcers: A qualitative systematic review

scientific article published on 10 May 2020

Finding the culprit: a review of the influences of proteases on the chronic wound environment.

scientific article published on 22 January 2009

Functional and mechanistic investigation of Shikonin in scarring

scientific article published on 12 January 2015

Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture.

scientific article published in January 2009

Human pilot studies reveal the potential of a vitronectin: growth factor complex as a treatment for chronic wounds

Hyaluronic acid: evaluation as a potential delivery vehicle for vitronectin:growth factor complexes in wound healing applications

scientific article published on 30 March 2011

Hyperbaric oxygen stimulates epidermal reconstruction in human skin equivalents

scientific article published on 01 March 2007

Identification of vitronectin as a novel insulin-like growth factor-II binding protein

scientific article published on 01 June 1999

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding

scientific article published on 01 May 2020

In VitroInvestigations on the Effect of Dermal Fibroblasts on Keratinocyte Responses to Ultraviolet B Radiation

article

Increased matrix metalloproteinase-9 (MMP-9) activity observed in chronic wound fluid is related to the clinical severity of the ulcer

scientific article published on 16 February 2008

Influence of nutrition on hepatic IGF-I mRNA levels and plasma concentrations of IGF-I and IGF-II in meat-type chickens.

scientific article published in April 1996

Insulin-like growth factor-I and UVB photoprotection in human keratinocytes.

scientific article

Insulin-like growth factor-I effect on chicken hepatoma cells (LMH) is inhibited by endogenous IGF-binding proteins

scientific article published on 01 April 1998

Insulin-like growth factor-I rescue of primary keratinocytes from pre- and post-ultraviolet B radiation effects

scientific article published on 03 July 2020

Insulin-like growth factor-I:vitronectin complex-induced changes in gene expression effect breast cell survival and migration

scientific article published on 8 February 2011

Insulin-like growth factor-II bound to vitronectin enhances MCF-7 breast cancer cell migration

scientific article published on 01 June 2003

Insulin-like growth factors (IGF) and IGF-binding proteins bound to vitronectin enhance keratinocyte protein synthesis and migration

scientific article

Insulin-like growth factors in poultry.

scientific article published on July 1997

Investigating the potential of Shikonin as a novel hypertrophic scar treatment

scientific article

Kangaroo IGF-II is structurally and functionally similar to the human [Ser29]-IGF-II variant

scientific article published on 01 June 1999

Lysine residues of IGF-I are substrates for transglutaminases and modulate downstream IGF-I signalling

scientific article published on 11 September 2013

MS-based metabolomics facilitates the discovery of in vivo functional small molecules with a diversity of biological contexts.

scientific article

Mathematical modelling of aerosolised skin grafts incorporating keratinocyte clonal subtypes

scientific article published on 20 October 2006

Mechanistic investigations into interactions between IGF-I and IGFBPs and their impact on facilitating cell migration on vitronectin.

scientific article published on October 2010

Migration of breast cancer cells: understanding the roles of volume exclusion and cell-to-cell adhesion

scientific article published on October 2010

Optimized delivery of skin keratinocytes by aerosolization and suspension in fibrin tissue adhesive.

scientific article published in May 2006

Organotypic culture of normal, dysplastic and squamous cell carcinoma-derived oral cell lines reveals loss of spatial regulation of CD44 and p75 NTR in malignancy.

scientific article published on 29 May 2012

PEGylation of lysine residues reduces the pro-migratory activity of IGF-I.

scientific article published on 23 June 2013

Plasma clearance and tissue distribution of labelled chicken and human IGF-I and IGF-II in the chicken

scientific article published on 01 July 1996

Potential pitfalls of radiolabel adsorption to ceramic biomaterials.

scientific article published on March 2005

Preparation of cultured skin for transplantation using insulin-like growth factor I in conjunction with insulin-like growth factor binding protein 5, epidermal growth factor, and vitronectin.

scientific article published in June 2006

Prevalence of chronic wounds in the general population: systematic review and meta-analysis of observational studies

scientific article published on 12 November 2018

Production of a human epidermal growth factor fusion protein and its degradation in rat gastrointestinal flushings.

scientific article

Production, in vitro characterisation, in vivo clearance, and tissue localisation of recombinant barramundi (Lates calcarifer) insulin-like growth factor II

scientific article published on 01 July 2001

Proteomics in chronic wound research: potentials in healing and health

scientific article published on 14 January 2010

Provisional Matrix Deposition in Hemostasis and Venous Insufficiency: Tissue Preconditioning for Nonhealing Venous Ulcers.

scientific article

Purification, amino acid sequence and characterisation of kangaroo IGF-I ⬇️

scientific article published on January 1, 1998

Recent advances in dermal wound healing: biomedical device approaches

scientific article published on January 2010

Responses of keratinocytes to substrate-bound vitronectin: growth factor complexes.

scientific article

Sensors and imaging for wound healing: a review

scientific article published on 28 September 2012

Serum-free primary human fibroblast and keratinocyte coculture

scientific article published on April 2010

Severe hypoxia and malnutrition collectively contribute to scar fibroblast inhibition and cell apoptosis.

scientific article published on 22 September 2015

Shikonin reduces TGF-β1-induced collagen production and contraction in hypertrophic scar-derived human skin fibroblasts

scientific article

Structural and functional evidence for the interaction of insulin-like growth factors (IGFs) and IGF binding proteins with vitronectin.

scientific article published in July 2003

Substrate-bound insulin-like growth factor (IGF)-I-IGF binding protein-vitronectin-stimulated breast cell migration is enhanced by coactivation of the phosphatidylinositide 3-Kinase/AKT pathway by alphav-integrins and the IGF-I receptor.

scientific article published on 13 December 2007

Surface modification by complexes of vitronectin and growth factors for serum-free culture of human osteoblasts

scientific article published on November 2005

Targeting Insulin-Like Growth Factor-I and Extracellular Matrix Interactions in Melanoma Progression.

scientific article published on 12 January 2018

The effect of amphiphilic siloxane oligomers on fibroblast and keratinocyte proliferation and apoptosis

scientific article published on November 2010

The effect of matrix characteristics on fibroblast proliferation in 3D gels

scientific article published on 03 August 2010

The highly abundant urinary metabolite urobilin interferes with the bicinchoninic acid assay.

scientific article

The humanistic and economic burden of chronic wounds: A systematic review

article

The kangaroo cation-independent mannose 6-phosphate receptor binds insulin-like growth factor II with low affinity

scientific article published on 01 September 1999

The roles of hypoxia in the in vitro engineering of tissues

scientific article published on September 2007

Transglutaminases and receptor tyrosine kinases.

scientific article published on 11 October 2011

Unravelling the insulin-like growth factor I-mediated photoprotection of the skin

scientific article published on 18 November 2019

Uric acid and xanthine oxidoreductase in wound healing.

scientific article published on February 2014

Urinary biomarkers of physical activity: candidates and clinical utility.

scientific article published on 15 December 2013

Vitronectin modulates human mesenchymal stem cell response to insulin-like growth factor-I and transforming growth factor beta 1 in a serum-free environment

scientific article published on 01 June 2009

Vitronectin supports migratory responses of corneal epithelial cells to substrate bound IGF-I and HGF, and facilitates serum-free cultivation.

scientific article published on 16 October 2006

Vitronectin--master controller or micromanager?

scientific article published on 13 September 2013

Vitronectin: Growth Factor Complexes Hold Potential as a Wound Therapy Approach

scientific article published on 17 January 2008

Why australia and Indian researchers should collaborate to advance wound management innovation?

scientific article published on January 2013

Wound Care Innovation for the Tropics-An Industry-Facing Singaporean Initiative Focussed on Wounds and Wound Care in Asian Populations

scientific article published on 01 April 2018

Wound Healing and the Use of Medicinal Plants

scientific article published on 22 September 2019

Wound Management Innovation Cooperative Research Centre - a new model for inter-disciplinary wound research

scientific article published on 01 April 2012

Xanthine Oxidoreductase: A Novel Therapeutic Target for the Treatment of Chronic Wounds?

scientific article published in March 2018

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