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List of works by Bernd Rehm

A new metabolic link between fatty acid de novo synthesis and polyhydroxyalkanoic acid synthesis. The PHAG gene from Pseudomonas putida KT2440 encodes a 3-hydroxyacyl-acyl carrier protein-coenzyme a transferase.

scientific article published in September 1998

A phase I/II randomized, controlled, clinical trial for assessment of the efficacy and safety of β-D-mannuronic acid in rheumatoid arthritis patients.

scientific article

A sensitive, viable-colony staining method using Nile red for direct screening of bacteria that accumulate polyhydroxyalkanoic acids and other lipid storage compounds

scientific article

Activation Mechanism and Cellular Localization of Membrane-Anchored Alginate Polymerase in Pseudomonas aeruginosa.

scientific article published on 3 March 2017

Advanced liquid biopsy technologies for circulating biomarker detection

scientific article published on 24 October 2019

Alg44, a unique protein required for alginate biosynthesis in Pseudomonas aeruginosa

scientific journal article

Alginate Polymerization and Modification Are Linked in Pseudomonas aeruginosa.

scientific article

Alginate lyase fromPseudomonas aeruginosaCF1/M1 prefers the hexameric oligomannuronate as substrate ⬇️

scientific article published on 01 August 1998

An alginate-like exopolysaccharide biosynthesis gene cluster involved in biofilm aerial structure formation by Pseudomonas alkylphenolia.

scientific article published on 4 February 2014

Analysis of the alginate O-acetylation machinery in Pseudomonas aeruginosa

scientific article published on 04 January 2020

Antibody response of rabbits and cystic fibrosis patients to an alginate-specific outer membrane protein of a mucoid strain of Pseudomonas aeruginosa

scientific article published on 01 January 1994

Assessing the Performance of Floating Biofilters for Oxidation of Methane from Dairy Effluent Ponds.

scientific article published on March 2017

Assessment of farm soil, biochar, compost and weathered pine mulch to mitigate methane emissions.

scientific article published on 24 August 2016

Bacterial alginates: biosynthesis and applications ⬇️

scientific article published on September 1, 1997

Bacterial alginates: from biosynthesis to applications.

scientific article published on 16 August 2006

Bacterial biopolymers: from pathogenesis to advanced materials

scientific article published on 28 January 2020

Bacterial exopolysaccharides: biosynthesis pathways and engineering strategies

scientific article

Bacterial polyester inclusions engineered to display vaccine candidate antigens for use as a novel class of safe and efficient vaccine delivery agents.

scientific article published on 16 October 2009

Bacterial polyhydroxyalkanoate granules: biogenesis, structure, and potential use as nano-/micro-beads in biotechnological and biomedical applications.

scientific article published on April 2009

Bacterial polymers: biosynthesis, modifications and applications.

scientific article published on 28 June 2010

Bactericidal Compounds Controlling Growth of the Plant Pathogen Pseudomonas syringae pv. actinidiae, Which Forms Biofilms Composed of a Novel Exopolysaccharide

scientific article published on 3 April 2015

Biochemical Properties and Substrate Specificities of a Recombinantly Produced Azotobacter vinelandii Alginate Lyase ⬇️

scientific article published on August 1, 1998

Biochemical analysis of alginate biosynthesis protein AlgX from Pseudomonas aeruginosa: purification of an AlgX-MucD (AlgY) protein complex

scientific journal article

Biochemical and enzymological properties of the polyhydroxybutyrate synthase from the extremely halophilic archaeon strain 56.

scientific article published in July 2002

Biochemical and genetic analysis of PHA synthases and other proteins required for PHA synthesis.

scientific article

Biochemical characterization of the Pseudomonas putida 3-hydroxyacyl ACP:CoA transacylase, which diverts intermediates of fatty acid de novo biosynthesis.

scientific article published on 27 August 2002

Bioengineered polyester beads co-displaying protein and carbohydrate-based antigens induce protective immunity against bacterial infection

scientific article

Bioengineering a bacterial pathogen to assemble its own particulate vaccine capable of inducing cellular immunity

scientific article published on 02 February 2017

Bioengineering of Bacterial Polymer Inclusions Catalyzing the Synthesis of N -Acetylneuraminic Acid ⬇️

scientific article published on March 1, 2013

Bioengineering of bacteria to assemble custom-made polyester affinity resins

scientific article published on 24 October 2014

Bioengineering towards self-assembly of particulate vaccines

scientific article published on 30 March 2017

Biological function of a polysaccharide degrading enzyme in the periplasm.

scientific article published on 8 November 2016

Corrigendum to "Immunogencity of antigens from Mycobacterium tuberculosis self-assembled as particulate vaccines" [Int. J. Med. Microbiol. 306 (2016) 624-632]

scientific article published on 01 February 2017

Design of Modular Polyhydroxyalkanoate Scaffolds for Protein Immobilization by Directed Ligation

scientific article published on 24 September 2018

Design of a single-chain multi-enzyme fusion protein establishing the polyhydroxybutyrate biosynthesis pathway.

scientific article

Display of Antigens on Polyester Inclusions Lowers the Antigen Concentration Required for a Bovine Tuberculosis Skin Test

scientific article published on 28 October 2015

Dual Roles of Pseudomonas aeruginosa AlgE in Secretion of the Virulence Factor Alginate and Formation of the Secretion Complex ⬇️

scientific article published on January 18, 2013

Editorial: Microbial Exopolysaccharides: From Genes to Applications

scientific article

Engineering Bacillus megaterium for production of functional intracellular materials.

scientific article published on 22 November 2017

Engineering mycobacteria for the production of self-assembling biopolyesters displaying mycobacterial antigens for use as tuberculosis vaccine

scientific article published on 13 January 2017

Escherichia coli NemA is an efficient chromate reductase that can be biologically immobilized to provide a cell free system for remediation of hexavalent chromium.

scientific article

Evaluation of the efficacy and safety of β-d-mannuronic acid in patients with ankylosing spondylitis: A 12-week randomized, placebo-controlled, phase I/II clinical trial

scientific article published on 8 November 2017

Functional expression of the PHA synthase gene phaC1 from Pseudomonas aeruginosa in Escherichia coli results in poly(3-hydroxyalkanoate) synthesis.

scientific article

Genetics and regulation of bacterial alginate production

scientific article published on 18 February 2014

Gut-associated denitrification and in vivo emission of nitrous oxide by the earthworm families megascolecidae and lumbricidae in new zealand. ⬇️

scientific article published on 3 April 2009

Halopiger aswanensis sp. nov., a polymer-producing and extremely halophilic archaeon isolated from hypersaline soil.

scientific article

Heterologous expression of the acyl-acyl carrier protein thioesterase gene from the plant Umbellularia californica mediates polyhydroxyalkanoate biosynthesis in recombinant Escherichia coli.

scientific article published in March 2001

Identification of a periplasmic AlgK–AlgX–MucD multiprotein complex in Pseudomonas aeruginosa involved in biosynthesis and regulation of alginate ⬇️

scientific article published on June 29, 2011

Immobilization of active lipase B from Candida antarctica on the surface of polyhydroxyalkanoate inclusions.

scientific article

Immobilization of organophosphohydrolase OpdA from Agrobacterium radiobacter by overproduction at the surface of polyester inclusions inside engineered Escherichia coli.

scientific article published on 26 December 2011

Immunogencity of antigens from Mycobacterium tuberculosis self-assembled as particulate vaccines.

scientific article published on 13 October 2016

Immunological properties and protective efficacy of a single mycobacterial antigen displayed on polyhydroxybutyrate beads.

scientific article published on 17 July 2017

Impact of alginate overproduction on attachment and biofilm architecture of a supermucoid Pseudomonas aeruginosa strain

scientific article published on 31 July 2009

In vitro synthesis of poly(3-hydroxydecanoate): purification and enzymatic characterization of type II polyhydroxyalkanoate synthases PhaC1 and PhaC2 from Pseudomonas aeruginosa

scientific article published on 01 July 2000

In vivo enzyme immobilization by use of engineered polyhydroxyalkanoate synthase

scientific article

In vivo polyester immobilized sortase for tagless protein purification.

scientific article published on 25 November 2015

In vivo self-assembly of fluorescent protein microparticles displaying specific binding domains.

scientific article published in August 2013

Insights into the assembly of the alginate biosynthesis machinery in Pseudomonas aeruginosa.

scientific article published on 15 March 2013

Insights into the surface topology of polyhydroxyalkanoate synthase: self-assembly of functionalized inclusions

scientific article published on 07 June 2015

Introduction of β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression.

scientific article published on 25 April 2017

Letter to the Editor: Backbone resonance assignment of an aminoglycoside-3′-phosphotransferase type IIa

scientific article published on 01 January 2004

Membrane topology of outer membrane protein AlgE, which is required for alginate production in Pseudomonas aeruginosa

scientific article published on 22 January 2010

Membrane topology of the outer membrane protein OprH from Pseudomonas aeruginosa: PCR-mediated site-directed insertion and deletion mutagenesis

scientific article

Membrane-anchored MucR mediates nitrate-dependent regulation of alginate production in Pseudomonas aeruginosa.

scientific article published on 29 April 2015

Microbial alginate production, modification and its applications.

scientific article published on 19 August 2013

Molecular characterization of Alg8, a putative glycosyltransferase, involved in alginate polymerisation.

scientific article

Molecular characterization of the poly(3-hydroxybutyrate) (PHB) synthase from Ralstonia eutropha: in vitro evolution, site-specific mutagenesis and development of a PHB synthase protein model

article

New skin test for detection of bovine tuberculosis on the basis of antigen-displaying polyester inclusions produced by recombinant Escherichia coli.

scientific article

Nitrogen-dependent regulation of medium-chain length polyhydroxyalkanoate biosynthesis genes in pseudomonads

scientific article published on 01 February 2005

One-step production of immobilized alpha-amylase in recombinant Escherichia coli.

scientific article published on 5 February 2009

Oral administration effects of β-d-mannuronic acid (M2000) on Th17 and regulatory T cells in patients with ankylosing spondylitis.

scientific article published on 22 February 2018

Overexpression of algE in Escherichia coli: subcellular localization, purification, and ion channel properties

scientific article

PhaG-mediated synthesis of Poly(3-hydroxyalkanoates) consisting of medium-chain-length constituents from nonrelated carbon sources in recombinant Pseudomonas fragi.

scientific article published on May 2000

Poly(3-Hydroxybutyrate) Synthesis Genes in Azotobacter sp. Strain FA8 ⬇️

scientific article published on November 1, 2001

Polyester as Antigen Carrier toward Particulate Vaccines

scientific article published on 10 June 2019

Polyhydroxybutyrate biosynthesis in Caulobacter crescentus: molecular characterization of the polyhydroxybutyrate synthase.

scientific article published on December 2001

Polyhydroyxalkanoate synthase fusions as a strategy for oriented enzyme immobilisation.

scientific article

Production of M2000 (β-d-mannuronic acid) and its therapeutic effect on experimental nephritis.

scientific article

Production of a particulate hepatitis C vaccine candidate by an engineered Lactococcus lactis strain.

scientific article published on 7 October 2011

Protective T Cell and Antibody Immune Responses against Hepatitis C Virus Achieved Using a Biopolyester-Bead-Based Vaccine Delivery System

scientific article published on 17 February 2016

Protein engineering of streptavidin for in vivo assembly of streptavidin beads.

scientific article published on 17 February 2008

Protein engineering towards biotechnological production of bifunctional polyester beads.

scientific article

Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

scientific article published on 15 February 2017

Purification of target proteins from intracellular inclusions mediated by intein cleavable polyhydroxyalkanoate synthase fusions.

scientific article published on 2 November 2017

Purification of therapeutic proteins mediated by in vivo polyester immobilized sortase.

scientific article published on 9 November 2017

Recombinant Escherichia coli produces tailor-made biopolyester granules for applications in fluorescence activated cell sorting: functional display of the mouse interleukin-2 and myelin oligodendrocyte glycoprotein.

scientific article

Recombinant Escherichia coli strain produces a ZZ domain displaying biopolyester granules suitable for immunoglobulin G purification

scientific article

Recombinant protein production by in vivo polymer inclusion display.

scientific article published on 29 July 2011

Relevant uses of surface proteins--display on self-organized biological structures.

scientific article

Revaccination of cattle with bacille Calmette-Guérin two years after first vaccination when immunity has waned, boosted protection against challenge with Mycobacterium bovis.

scientific article

Role of PelF in Pel Polysaccharide Biosynthesis in Pseudomonas aeruginosa ⬇️

scientific article published on February 22, 2013

Role of exopolysaccharides in Pseudomonas aeruginosa biofilm formation and architecture

scientific article

Role of fatty acid de novo biosynthesis in polyhydroxyalkanoic acid (PHA) and rhamnolipid synthesis by pseudomonads: establishment of the transacylase (PhaG)-mediated pathway for PHA biosynthesis in Escherichia coli

scientific article

Self-assembled particulate PsaA as vaccine against Streptococcus pneumoniae infection

scientific article published on 11 April 2017

Sodium alginate as a novel therapeutic option in experimental colitis.

scientific article

Structural basis for alginate secretion across the bacterial outer membrane ⬇️

scientific article published on July 21, 2011

Surface display of highly-stable Desulfovibrio vulgaris carbonic anhydrase on polyester beads for CO2 capture.

scientific article published on 15 March 2015

Synthesis of poly(3-hydroxyalkanoates) in Escherichia coli expressing the PHA synthase gene phaC2 from Pseudomonas aeruginosa: comparison of PhaC1 and PhaC2

scientific article published on 01 December 1997

Synthetic biology towards the synthesis of custom-made polysaccharides.

scientific article

The effects of β-D-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte/macrophage, J774 cell line.

scientific article

The potent inhibitory effect of β-D-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property on anti-cyclic citrullinated peptide antibodies, rheumatoid factor and anti-dsDNA antibodies in patients with rheumatoid arthritis.

scientific article published on 21 March 2017

The role of polyhydroxyalkanoate biosynthesis by Pseudomonas aeruginosa in rhamnolipid and alginate production as well as stress tolerance and biofilm formation.

scientific article

Treatment of experimental arthritis with M2000, a novel designed non-steroidal anti-inflammatory drug.

scientific article

Treatment of experimental immune complex glomerulonephritis by sodium alginate.

scientific article

ZZ polyester beads: an efficient and simple method for purifying IgG from mouse hybridoma supernatants.

scientific article published on 24 April 2009

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