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List of works by David W. Thomas

'Toothache stories': a qualitative investigation of why and how people seek emergency dental care.

scientific article

'Young' oral fibroblasts are geno/phenotypically distinct

scientific article published on 01 December 2010

3D Bioprinting of Carboxymethylated-Periodate Oxidized Nanocellulose Constructs for Wound Dressing Applications

scientific article published on 19 May 2015

A Low-Molecular-Weight Alginate Oligosaccharide Disrupts Pseudomonal Microcolony Formation and Enhances Antibiotic Effectiveness.

scientific article

A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease

scientific article published on February 2016

A comparison of the ability of intra-oral and extra-oral fibroblasts to stimulate extracellular matrix reorganization in a model of wound contraction

scientific article published on 01 June 1996

A multipotent neural crest-derived progenitor cell population is resident within the oral mucosa lamina propria.

scientific article

A nanoscale characterization of the interaction of a novel alginate oligomer with the cell surface and motility of Pseudomonas aeruginosa

scientific article published in March 2014

A one-year review of maxillofacial sports injuries treated at an accident and emergency department.

scientific article published on February 1998

A prospective study of the microbiology of chronic venous leg ulcers to reevaluate the clinical predictive value of tissue biopsies and swabs.

scientific article published in January 2007

A randomised controlled trial of clinical outreach education to rationalise antibiotic prescribing for acute dental pain in the primary care setting

scientific article published on 01 August 2006

A review of the microbiology, antibiotic usage and resistance in chronic skin wounds.

scientific article

Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation.

scientific article published on October 2009

Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling.

scientific article published on 21 January 2010

Alginate Oligosaccharide-Induced Modification of the lasI-lasR and rhlI-rhlR Quorum Sensing Systems in Pseudomonas aeruginosa

scientific article published on 20 February 2018

Alginate oligosaccharides inhibit fungal cell growth and potentiate the activity of antifungals against Candida and Aspergillus spp

scientific article

Alginate oligosaccharides modify hyphal infiltration of Candida albicans in an in vitro model of invasive human candidosis.

scientific article

An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype

scientific article published on 01 February 2003

An audit of antibiotic prescribing in third molar surgery

scientific article published on 01 April 1997

An in vitro comparison of two silver-containing antimicrobial wound dressings .

scientific article

An in vitro model of chronic wound biofilms to test wound dressings and assess antimicrobial susceptibilities.

scientific article published on 8 April 2010

An in vitro study of alginate oligomer therapies on oral biofilms.

scientific article published on 30 July 2013

An investigation into the efficacy of intravenous diclofenac in post-operative dental pain.

scientific article

An investigation of Pseudomonas aeruginosa biofilm growth on novel nanocellulose fibre dressings.

scientific article published on 22 October 2015

An investigation of preferential fibroblast wound repopulation using a novel in vitro wound model

scientific article published on 01 November 1997

An investigation of the interaction between alcohol and fibroblasts in wound healing.

scientific article

Anaerobic cocci populating the deep tissues of chronic wounds impair cellular wound healing responses in vitro

scientific article published on 01 March 2003

Anti-pseudomonad Activity of Manuka Honey and Antibiotics in a Specialized Model Simulating Cystic Fibrosis Lung Infection

scientific article published on 24 April 2019

Antibiotic prescribing for chronic skin wounds in primary care

scientific article published on 01 July 2006

Antibiotic prescribing for dental conditions: general medical practitioners and dentists compared

scientific article published on 01 April 2000

Antibiotic prescription for acute dental conditions in the primary care setting

scientific article published on 01 December 1996

Antimicrobial tolerance and the significance of persister cells in recalcitrant chronic wound biofilms ⬇️

scientific article published on January 1, 2011

Anxiety and self-consciousness in patients with facial lacerations one week and six months later.

scientific article published on 15 December 2005

Anxiety and self-consciousness in patients with minor facial lacerations.

scientific article published in August 2004

Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms

scientific article published on 12 December 2017

Bi-Functional Alginate Oligosaccharide-Polymyxin Conjugates for Improved Treatment of Multidrug-Resistant Gram-Negative Bacterial Infections

scientific article published on 11 November 2020

Bioresponsive dextrin-rhEGF conjugates: in vitro evaluation in models relevant to its proposed use as a treatment for chronic wounds.

scientific article

Bispecific antibody-mediated detection of the Staphylococcus aureus thermonuclease

scientific article published on 28 June 2012

Cellulose Nanofibril Formulations Incorporating a Low-Molecular-Weight Alginate Oligosaccharide Modify Bacterial Biofilm Development

scientific article published on 11 July 2019

Colistin in burn intensive care: back to the future?

scientific article published on 04 August 2012

Colistin past and future: a bibliographic analysis.

scientific article published on 2 July 2012

Comparison of oxidative stress biomarker profiles between acute and chronic wound environments.

scientific article

Compensatory mutations modulate the competitiveness and dynamics of plasmid-mediated colistin resistance in Escherichia coli clones

scientific article published on 02 January 2020

Contrasting host immuno-inflammatory responses to bacterial challenge within venous and diabetic ulcers.

scientific article

Controlled release of dextrin-conjugated growth factors to support growth and differentiation of neural stem cells

scientific article published on 06 October 2018

Crosslinking and G-protein functions of transglutaminase 2 contribute differentially to fibroblast wound healing responses.

scientific article published on 15 June 2004

Defective extracellular matrix reorganization by chronic wound fibroblasts is associated with alterations in TIMP-1, TIMP-2, and MMP-2 activity

scientific article published on 01 August 2000

Deletion of the homeobox gene PRX-2 affects fetal but not adult fibroblast wound healing responses.

scientific article published in January 2003

Development and Characterisation of a Human Chronic Skin Wound Cell Line-Towards an Alternative for Animal Experimentation.

scientific article published on 27 March 2018

Development and validation of an in vitro pharmacokinetic/pharmacodynamic model to test the antibacterial efficacy of antibiotic polymer conjugates

scientific article

Dextrin-colistin conjugates as a model bioresponsive treatment for multidrug resistant bacterial infections.

scientific article

Dextrin-rhEGF conjugates as bioresponsive nanomedicines for wound repair.

scientific article

Differential Expression of Matrix Metalloproteinases During Impaired Wound Healing of the Diabetes Mouse

scientific article published on 01 July 2002

Differential cellular and microbial responses to nano-/micron-scale titanium surface roughness induced by hydrogen peroxide treatment

scientific article published on 28 March 2012

Ectopic submandibular gland presenting as a swelling in the floor of mouth

scientific article published on 01 November 2005

Epstein-Barr virus in squamous cell carcinoma after renal transplantation.

scientific article

Evaluation of hyaluronic acid-protein conjugates for polymer masked-unmasked protein therapy.

scientific article published on October 2010

Evaluation of the physical and biological properties of hyaluronan and hyaluronan fragments

scientific article published on 22 August 2011

Heterogeneity within the gram-positive anaerobic cocci demonstrated by analysis of 16S-23S intergenic ribosomal RNA polymorphisms.

scientific article

Identification of a transcriptional signature for the wound healing continuum

scientific article

In Vitro Evaluation of the Interaction of Dextrin-Colistin Conjugates with Bacterial Lipopolysaccharide

scientific article published on 5 January 2016

In vitro interaction of chronic wound bacteria in biofilms

scientific article published on 01 December 2011

Inflammation and wound healing: the role of bacteria in the immuno-regulation of wound healing

scientific article published on 01 December 2004

Involvement of hyaluronan in regulation of fibroblast phenotype.

scientific article

Lhermitte-Duclos disease associated with Cowden's disease

scientific article published on 01 October 1995

Molecular analysis of the microflora in chronic venous leg ulceration.

scientific article published in April 2003

Molecular characterisation of tumour infiltrating lymphocytes in oral squamous cell carcinoma

scientific article published on 01 March 1998

Mucosal cell-mediated immunological changes associated with experimental graft-versus-host disease.

scientific article

Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers

scientific article published on 27 May 2010

Optimisation of the hydrogen peroxide pre-treatment of titanium: surface characterisation and protein adsorption.

scientific article published in December 2008

Out-of-hours dental services: a survey of current provision in the United Kingdom

scientific article published on 01 March 2000

Overcoming drug resistance with alginate oligosaccharides able to potentiate the action of selected antibiotics.

scientific article

Paget's disease of bone: current concepts in pathogenesis and treatment.

scientific article

Patient presentation at medical practices with dental problems: an analysis of the 1996 General Practice Morbidity Database for Wales

scientific article published on 01 March 1999

Phenotypic variation in the production of bioactive hepatocyte growth factor/scatter factor by oral mucosal and skin fibroblasts

scientific article published on 01 January 2001

Polymer Masked-Unmasked Protein Therapy: Identification of the Active Species after Amylase Activation of Dextrin-Colistin Conjugates

scientific article published on 05 June 2019

Potential role of anaerobic cocci in impaired human wound healing.

scientific article

Randomized clinical trial of the effect of semi-occlusive dressings on the microflora and clinical outcome of acute facial wounds

scientific article published on 01 July 2000

Risk factors in the development of cyclosporine-induced gingival overgrowth

scientific article published on 01 February 2000

Skin and oral fibroblasts exhibit phenotypic differences in extracellular matrix reorganization and matrix metalloproteinase activity

scientific article published on 01 February 2001

Specific protease activity indicates the degree of Pseudomonas aeruginosa infection in chronic infected wounds.

scientific article published on 26 January 2012

T cell receptor Vbeta repertoire of tumour-infiltrating lymphocytes in oral squamous-cell carcinoma

scientific article published on 01 January 1996

T-cell receptor V beta usage by lesional lymphocytes in oral lichen planus

scientific article published on 01 March 1997

Targeted disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate oligosaccharides.

scientific article

The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinses

scientific article published in June 2022

The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption.

scientific article

The cellular proliferative phase of the wound repair process.

scientific article

The effect of alginate oligosaccharides on the mechanical properties of Gram-negative biofilms.

scientific article published in January 2013

The effect of dextrin-rhEGF on the healing of full-thickness, excisional wounds in the (db/db) diabetic mouse.

scientific article published on 22 March 2011

The effectiveness of out-of-hours dental services: I. Pain relief and oral health outcome.

scientific article

The effectiveness of out-of-hours dental services: II. patient satisfaction

scientific article published on 01 February 2005

The enhanced permeability retention effect: a new paradigm for drug targeting in infection.

scientific article published on 10 October 2012

The interaction of wood nanocellulose dressings and the wound pathogen P. aeruginosa.

scientific article published on 29 November 2016

The management and repair of wounds of the face

scientific article published on 01 September 1995

The visualisation and speed of kill of wound isolates on a silver alginate dressing ⬇️

scientific article published on March 8, 2012

Trends in the management of fractured mandibles 1983-93.

scientific article published in January 1994

Trends in the referral and treatment of new patients at a free emergency dental clinic since 1989

scientific article published on 01 January 1997

Use of 16S ribosomal DNA PCR and denaturing gradient gel electrophoresis for analysis of the microfloras of healing and nonhealing chronic venous leg ulcers.

scientific article

Use of molecular techniques to study microbial diversity in the skin: chronic wounds reevaluated.

scientific article

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