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List of works by Rocio I. Macias

A Novel Serum Metabolomic Profile for the Differential Diagnosis of Distal Cholangiocarcinoma and Pancreatic Ductal Adenocarcinoma

scientific article published on 31 May 2020

Causes of hOCT1-Dependent Cholangiocarcinoma Resistance to Sorafenib and Sensitization by Tumor-Selective Gene Therapy

article

Cellular Mechanisms Accounting for the Refractoriness of Colorectal Carcinoma to Pharmacological Treatment

scientific article published on 11 September 2020

Changes in the expression of genes related to bile acid synthesis and transport by the rat liver during hepatocarcinogenesis.

scientific article published in August 2005

Characterization of the role of ABCG2 as a bile acid transporter in liver and placenta.

scientific article

Cholangiocarcinoma 2020: the next horizon in mechanisms and management

scientific article published on 30 June 2020

Cholephilic characteristics of a new cytostatic complex of cisplatin with glycocholate (Bamet-R2)

scientific article published on 01 February 1999

Cocarcinogenic effects of intrahepatic bile acid accumulation in cholangiocarcinoma development.

scientific article published on 19 November 2013

DNA interaction and cytostatic activity of the new liver organotropic complex of cisplatin with glycocholic acid: Bamet-R2.

scientific article

Development and characterization of mouse monoclonal antibodies to eight human complement components: Analysis of reactivity with orthologs of nine mammalian genera

scientific article published on 24 November 2018

Diagnostic and prognostic biomarkers in cholangiocarcinoma

scientific article published on 01 May 2019

Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system.

scientific article published on 10 August 2005

Effect of maternal cholestasis and treatment with ursodeoxycholic acid on the expression of genes involved in the secretion of biliary lipids by the neonatal rat liver.

scientific article

Effect of maternal cholestasis on TGR5 expression in human and rat placenta at term.

scientific article published on 10 July 2013

Effect of maternal obstructive cholestasis during pregnancy on the biliary transport of horseradish peroxidase in the rat offspring.

scientific article published in September 2003

Effect of ursodeoxycholic acid treatment on the altered progesterone and bile acid homeostasis in the mother-placenta-foetus trio during cholestasis of pregnancy

scientific article

Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT).

scientific article published on 13 August 2015

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

scientific article published on 11 February 2019

Excretion of biliary compounds during intrauterine life.

scientific article published on February 2009

Excretion of fetal biliverdin by the rat placenta-maternal liver tandem.

scientific article published on 3 November 2005

Excretion of foetal bilirubin by the rat placenta-maternal liver tandem.

scientific article published in May 2003

Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).

scientific article published on 20 April 2016

Expression in human trophoblast and choriocarcinoma cell lines, BeWo, Jeg-3 and JAr of genes involved in the hepatobiliary-like excretory function of the placenta.

scientific article published on 19 May 2006

Expression of SLC22A1 variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib.

scientific article published on 30 July 2013

Further characterization of the electrogenicity and pH sensitivity of the human organic anion-transporting polypeptides OATP1B1 and OATP1B3.

scientific article published on 20 December 2010

Further evidence of the usefulness of bile acids as molecules for shuttling cytostatic drugs toward liver tumors.

scientific article published in September 1999

Genetic Variants in Genes Involved in Mechanisms of Chemoresistance to Anticancer Drugs ⬇️

scientific article published on May 1, 2012

Hepatic expression of sodium-dependent vitamin C transporters: ontogeny, subtissular distribution and effect of chronic liver diseases.

scientific article

Hepatoprotection of Mentha aquatica L., Lavandula dentata L. and Leonurus cardiaca L

scientific article published on 02 August 2019

In vitro test to determine the effect of cytostatic drugs on co-cultured rat hepatocytes and hepatoma cells

scientific article published on 01 April 1998

Inhibition of the intestinal absorption of bile acids using cationic derivatives: mechanism and repercussions.

scientific article published on 20 October 2006

Lactation during cholestasis: Role of ABC proteins in bile acid traffic across the mammary gland.

scientific article

Liver metabolic/oxidative stress induces hepatic and extrahepatic changes in the expression of the vitamin C transporters SVCT1 and SVCT2.

scientific article published on 26 May 2013

Liver metastases of intrahepatic cholangiocarcinoma: implications for a potential new staging system

scientific article published on 18 October 2020

Maternal cholestasis induces placental oxidative stress and apoptosis. Protective effect of ursodeoxycholic acid.

scientific article published on 27 January 2005

Mechanisms of Anticancer Drug Resistance in Hepatoblastoma

scientific article published on 22 March 2019

Models for Understanding Resistance to Chemotherapy in Liver Cancer

scientific article published on 29 October 2019

Molecular Bases of Drug Resistance in Hepatocellular Carcinoma

scientific article published on 23 June 2020

Molecular Bases of Mechanisms Accounting for Drug Resistance in Gastric Adenocarcinoma

scientific article published on 30 July 2020

Molecular bases of the fetal liver-placenta-maternal liver excretory pathway for cholephilic compounds.

scientific article published on April 2008

Molecular pathogenesis of intrahepatic cholestasis of pregnancy.

scientific article published on 28 March 2008

No correlation between the expression of FXR and genes involved in multidrug resistance phenotype of primary liver tumors.

scientific article

Novel cationic and neutral glycocholic acid and polyamine conjugates able to inhibit transporters involved in hepatic and intestinal bile acid uptake.

scientific article published on 19 January 2007

OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes?

scientific article

Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis.

scientific article published in March 2007

Oxidative stress and apoptosis in fetal rat liver induced by maternal cholestasis. Protective effect of ursodeoxycholic acid.

scientific article published in August 2005

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

scientific article published on 21 June 2020

Plasma Membrane Transporters as Biomarkers and Molecular Targets in Cholangiocarcinoma

scientific article published on 21 February 2020

Protective effect of bile acid derivatives in phalloidin-induced rat liver toxicity.

scientific article published on 4 May 2009

Rat liver transport and biotransformation of a cytostatic complex of bis-cholylglycinate and platinum (II)

scientific article published on 01 March 1998

Relationship between early onset severe intrahepatic cholestasis of pregnancy and higher risk of meconium-stained fluid.

scientific article

Relationship between tumor cell load and sensitivity to the cytostatic effect of two novel platinum-bile acid complexes, Bamet-D3 and Bamet-UD2.

scientific article published in August 2002

Reversible impairment of neonatal hepatobiliary function by maternal cholestasis

scientific article published on 01 May 1996

Role of drug transport and metabolism in the chemoresistance of acute myeloid leukemia

scientific article published on 18 August 2015

Role of macrophages in bile acid-induced inflammatory response of fetal lung during maternal cholestasis.

scientific article

Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin.

scientific article published in May 2003

Role of the placenta in serum autotaxin elevation during maternal cholestasis

scientific article published on 21 June 2018

Sensitizing gastric adenocarcinoma to chemotherapy by pharmacological manipulation of drug transporters

scientific article published on 24 October 2019

Serum lipidome unravels a diagnostic potential in bile acid diarrhoea

scientific article published in 2023

Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma and primary sclerosing cholangitis

scientific article published on 14 February 2019

Structural characterization, kinetic studies, and in vitro biological activity of new cis-diamminebis-cholylglycinate(O,O') Pt(II) and cis-diamminebis-ursodeoxycholate(O,O') Pt(II) complexes.

scientific article

Synthesis and Characterization of the New Cytostatic Complexcis-Diammineplatinum(II)−Chlorocholylglycinate

scientific article published on 01 July 1997

The hepatobiliary-like excretory function of the placenta. A review.

scientific article

The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy

scientific article

Up-regulation of FXR isoforms is not required for stimulation of the expression of genes involved in the lack of response of colon cancer to chemotherapy.

scientific article published on 8 August 2012

Usefulness of liposomes loaded with cytostatic bile acid derivatives to circumvent chemotherapy resistance of enterohepatic tumors.

scientific article published in March 2003

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