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List of works by Didier Negre

A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice.

scientific article published on 23 November 2011

An acidic cluster of the cytoplasmic tail of the RD114 virus glycoprotein controls assembly of retroviral envelopes.

scientific article

Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency

scientific article published on 01 February 2019

Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs.

scientific article

Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.

scientific article published on 29 September 2016

Cell cycle features of primate embryonic stem cells.

scientific article published on 20 October 2005

Cra-dependent transcriptional activation of the icd gene of Escherichia coli.

scientific article

Definition of a consensus DNA-binding site for the Escherichia coli pleiotropic regulatory protein, FruR.

scientific article published in July 1996

Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors.

scientific article

Escherichia coli isocitrate dehydrogenase kinase/phosphatase. Overproduction and kinetics of interaction with its substrates by using intrinsic fluorescence and fluorescent nucleotide analogues.

scientific article

FruR-mediated transcriptional activation at the ppsA promoter of Escherichia coli

scientific article published on 01 February 1998

GFP-transduced CD34+ and Lin- CD34- hematopoietic stem cells did not adopt a cardiac phenotype in a nonhuman primate model of myocardial infarct.

scientific article published in April 2007

Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.

scientific article

Heparan sulfate-dependent enhancement of henipavirus infection.

scientific article published on 10 March 2015

In vitro asymmetric binding of the pleiotropic regulatory protein, FruR, to the ace operator controlling glyoxylate shunt enzyme synthesis.

scientific article

Inactivation of the IGF-I receptor gene in primary Sertoli cells highlights the autocrine effects of IGF-I.

scientific article published in September 2007

Lentiviral transduction of human hematopoietic cells by HIV-1- and SIV-based vectors containing a bicistronic cassette driven by various internal promoters.

scientific article published in September 2005

Lentiviral vectors derived from simian immunodeficiency virus.

scientific article

Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates.

scientific article published on August 2002

Low titer lentiviral transgenesis in rodents with simian immundeficiency virus vector.

scientific article published on September 2013

Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent

scientific article published on 24 October 2017

Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent lymphocytes requires binding to both SLAM and CD46 entry receptors.

scientific article published on 30 March 2011

Mouse ES cells over-expressing the transcription factor NeuroD1 show increased differentiation towards endocrine lineages and insulin-expressing cells.

scientific article published in January 2009

Murine granulocyte-macrophage colony-stimulating factor expressed from a bicistronic simian immunodeficiency virus-based integrase-defective lentiviral vector does not enhance T-cell responses in mice.

scientific article

Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.

scientific article

Overproduction, purification and structural characterization of the functional N-terminal DNA-binding domain of the fru repressor from Escherichia coli K-12

scientific article published on 01 February 1995

Production of SIV vectors for gene delivery.

scientific article published in April 2011

Production of lentiviruses displaying ''early-acting'' cytokines for selective gene transfer into hematopoietic stem cells.

scientific article published in January 2008

Role of adiponectin receptors, AdipoR1 and AdipoR2, in the steroidogenesis of the human granulosa tumor cell line, KGN.

scientific article

SIV Vectors

scientific article published on 01 January 2003

Specific interactions between the IclR repressor of the acetate operon of Escherichia coli and its operator

scientific article published on November 5, 1992

Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins.

scientific article published on 23 September 2008

Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.

scientific article

The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway

scientific journal article

Three-dimensional structure of the DNA-binding domain of the fructose repressor from Escherichia coli by 1H and 15N NMR ⬇️

scientific article published on July 18, 1997

p38 mitogen activated protein kinase controls two successive-steps during the early mesodermal commitment of embryonic stem cells.

scientific article published on 24 November 2010

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