List of works - Eleni Douni

2,2'-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1.

scientific article

A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF

scientific article published on 07 November 2011

A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.

scientific article

A splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in mice

scientific article (publication date: 2014)

Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

scientific article

Current Status and Future Prospects of Small-molecule Protein-protein Interaction (PPI) Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)

scientific article published on 01 January 2018

Designer xanthone: an inhibitor scaffold for MDR-involved human glutathione transferase isoenzyme A1-1.

scientific article published on 7 June 2013

Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice.

scientific article published on April 1996

Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice.

scholarly article

FELASA guidelines for the refinement of methods for genotyping genetically-modified rodents: a report of the Federation of European Laboratory Animal Science Associations Working Group

scientific article published on 01 July 2013

In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)

scientific article published on 25 July 2018

In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

article

Irisin: good or bad for the bone? A new path forward after the reported discovery of irisin receptor?

scientific article published on 25 January 2019

MUGEN mouse database; animal models of human immunological diseases

scientific article

Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice

scientific article published on 07 October 2019

New Insights for RANKL as a Proinflammatory Modulator in Modeled Inflammatory Arthritis

scientific article published on 05 February 2019

Novel genetic models of osteoporosis by overexpression of human RANKL in transgenic mice

scientific article published on 01 January 2014

Novel insights into SLC25A46-related pathologies in a genetic mouse model

scientific article

RANKL inhibition improves muscle strength and insulin sensitivity and restores bone mass

scientific article published on 23 May 2019

Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects

scientific article published on 27 August 2014

Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice.

scientific article

Solvent Selection for Insoluble Ligands, a Challenge for Biological Assay Development: A TNF-α/SPD304 Study

scientific article

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

scientific journal article

The unbearable lightness of bone marrow homeostasis.

scientific article published on 26 December 2014

Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution

scientific article published on 18 May 2018

Tumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn's disease and promotes experimental colitis in vivo

scientific article published on 01 November 2002

Tumour necrosis factors in immune regulation: everything that's interesting is...new!

scientific article published on October 1996

List of works by Eleni Douni

2,2'-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1.

A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF

A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.

A splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in mice

Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

Current Status and Future Prospects of Small-molecule Protein-protein Interaction (PPI) Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)

Designer xanthone: an inhibitor scaffold for MDR-involved human glutathione transferase isoenzyme A1-1.

Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice.

Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice.

FELASA guidelines for the refinement of methods for genotyping genetically-modified rodents: a report of the Federation of European Laboratory Animal Science Associations Working Group

In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)

In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

Irisin: good or bad for the bone? A new path forward after the reported discovery of irisin receptor?

MUGEN mouse database; animal models of human immunological diseases

Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice

New Insights for RANKL as a Proinflammatory Modulator in Modeled Inflammatory Arthritis

Novel genetic models of osteoporosis by overexpression of human RANKL in transgenic mice

Novel insights into SLC25A46-related pathologies in a genetic mouse model

RANKL inhibition improves muscle strength and insulin sensitivity and restores bone mass

Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects

Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice.

Solvent Selection for Insoluble Ligands, a Challenge for Biological Assay Development: A TNF-α/SPD304 Study

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

The unbearable lightness of bone marrow homeostasis.

Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution

Tumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn's disease and promotes experimental colitis in vivo

Tumour necrosis factors in immune regulation: everything that's interesting is...new!