List of works by Martin Widschwendter

A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival

scientific article

A Mouse Model That Reproduces the Developmental Pathways and Site Specificity of the Cancers Associated With the Human BRCA1 Mutation Carrier State

scientific article

A SYSTEMATIC REVIEW ON COST-EFFECTIVENESS STUDIES EVALUATING OVARIAN CANCER EARLY DETECTION AND PREVENTION STRATEGIES

scientific article published on 18 February 2020

A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases

scientific article published on 25 June 2019

A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform.

scientific article

A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation

scientific article

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

scientific article published on 19 September 2010

A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix.

scientific article published on 25 April 2018

A prospective evaluation of the IOTA Logistic Regression Models (LR1 and LR2) in comparison to Subjective Pattern Recognition for the diagnosis of ovarian cancer in the outpatient setting.

scientific article published on 4 October 2017

A prospective validation of the IOTA logistic regression models (LR1 and LR2) in comparison to subjective pattern recognition for the diagnosis of ovarian cancer.

scientific article

A randomised controlled trial comparing surgical intervention rates between two protocols for the management of asymptomatic adnexal tumours in postmenopausal women

scientific article

A systems-level integrative framework for genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control

scientific article

Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer

scientific article published on 18 December 2016

Accounting for differential variability in detecting differentially methylated regions

scientific article published on 01 January 2019

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.

scientific article

Alveolar echinococcosis with bulky peritoneal spread--a rare but important diagnosis in gynaecological practice

scientific article published on 01 May 2000

An epigenetic signature in peripheral blood predicts active ovarian cancer

scientific article

An integrative pan-cancer-wide analysis of epigenetic enzymes reveals universal patterns of epigenomic deregulation in cancer

scientific article published on 14 July 2015

Antiproliferative activity and apoptosis induced by retinoic acid receptor-gamma selectively binding retinoids in neuroblastoma.

scientific article published on May 1998

Are objective measures of physical capability related to accelerated epigenetic age? Findings from a British birth cohort.

scientific article published in November 2017

Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study

scientific article published on 09 July 2019

Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen.

scientific article published on June 2004

Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study

scientific article published on 30 July 2018

Association of serum sex steroid receptor bioactivity and sex steroid hormones with breast cancer risk in postmenopausal women

scientific article published on 10 April 2012

Bilateral nipple ulcers in a breastfeeding woman: a manifestation of Behcet's disease?

scientific article published on 01 October 2000

Brca1 Mutations Enhance Mouse Reproductive Functions by Increasing Responsiveness to Male-Derived Scent.

scientific article published on 21 October 2015

Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer.

scientific article published in January 2006

Circulating Methylated DNA: A New Generation of Tumor Markers

scientific article published on 15 December 2006

Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints.

scientific article

Clinical significance of serum and ascitic p53 autoantibodies in epithelial ovarian carcinoma.

scientific article

Comparison of two protocols for the management of asymptomatic postmenopausal women with adnexal tumours - a randomised controlled trial of RMI/RCOG vs Simple Rules.

scientific article

Correction: The Dynamics and Prognostic Potential of DNA Methylation Changes at Stem Cell Gene Loci in Women's Cancer

article

Correlation of an epigenetic mitotic clock with cancer risk

scientific article

Corruption of the intra-gene DNA methylation architecture is a hallmark of cancer

scientific article

Cost-Effectiveness of Early Detection and Prevention Strategies for Endometrial Cancer-A Systematic Review

scientific article published on 11 July 2020

DNA Methylation Patterns in Normal Tissue Correlate more Strongly with Breast Cancer Status than Copy-Number Variants.

scientific article

DNA Methylation Signatures in Vaginal Fluid Samples for Detection of Cervical and Endometrial Cancer.

scientific article published on 2 June 2016

DNA hypomethylation and ovarian cancer biology.

scientific article published in July 2004

DNA methylation analysis in liquid-based cytology for cervical cancer screening.

scientific article published in December 2009

DNA methylation and breast carcinogenesis.

scientific article

DNA methylation markers for early detection of women's cancer: promise and challenges.

scientific article

DNA methylation of polycomb group target genes in cores taken from breast cancer centre and periphery.

scientific article published on 8 April 2009

DNA methylation signatures to predict the cervicovaginal microbiome status

scientific article published on 23 November 2020

Detection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer.

scientific article published on July 2006

Development and validation of a method for profiling post-translational modification activities using protein microarrays.

scientific article

Development and validation of the gene-expression Predictor of high-grade-serous Ovarian carcinoma molecular subTYPE (PrOTYPE)

scientific article published on 17 June 2020

Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions.

scientific article published on 6 April 2012

Distinctive topology of age-associated epigenetic drift in the human interactome

scientific article published on 12 August 2013

Do cancer risk and benefit-harm ratios influence women's consideration of risk-reducing mastectomy? A scenario-based experiment in five European countries.

scientific article

Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

scientific article published on 12 October 2017

Effects of Taxol on choriocarcinoma cells

scientific article published on 01 December 1995

Effects of type-I and -II interferons on 90K antigen expression in ovarian carcinoma cells

scientific article published on 01 December 1994

Elevated mRNA expression of CHAC1 splicing variants is associated with poor outcome for breast and ovarian cancer patients

scientific article published on 22 November 2011

Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer.

scientific article published on 3 June 2016

Epigenetic downregulation of the retinoic acid receptor-beta2 gene in breast cancer.

scientific article

Epigenetic drift, epigenetic clocks and cancer risk.

scientific article published on 22 April 2016

Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution

scientific article published on 24 May 2016

Epigenetics makes its mark on women-specific cancers--an opportunity to redefine oncological approaches?

scientific article published on October 2012

Epigenotyping in peripheral blood cell DNA and breast cancer risk: a proof of principle study

scientific article

Ethical, Legal, and Regulatory Issues for the Implementation of Omics-Based Risk Prediction of Women's Cancer: Points to Consider

scientific article published on 17 September 2018

Expression of retinoic acid receptors in non-neoplastic epithelial disorders of the vulva and normal vulvar skin.

scientific article published on April 2000

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

scientific article published in October 2007

Fooled by the film: delayed diagnosis of incarcerated small-bowel hernia after laparoscopic surgery for endometrial cancer

scientific article published on 01 February 2012

Fulminant recurrence of a Sertoli-Leydig cell tumour during pregnancy

scientific article published on 01 March 1999

GALR1 methylation in vaginal swabs is highly accurate in identifying women with endometrial cancer.

scientific article published in July 2013

Genome-scale screen for DNA methylation-based detection markers for ovarian cancer

scientific article (publication date: 2011)

Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip.

scientific article published on 29 April 2010

Guidelines for treatment of breast carcinoma by the Gynecological Oncology Working Group. Gynecological Oncology Working Group

scientific article published on 01 January 1999

HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer

scientific article

HOXA methylation in normal endometrium from premenopausal women is associated with the presence of ovarian cancer: a proof of principle study.

scientific article published in November 2009

HOXA11 DNA methylation--a novel prognostic biomarker in ovarian cancer

scientific article published on 01 August 2008

High serum levels of soluble CD44 variant isoform v5 are associated with favourable clinical outcome in ovarian cancer.

scientific article published in January 1997

Histological confirmation of breast cancer registration and self-reporting in England and Wales: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening.

scientific article published on 17 May 2012

Human exposome assessment platform

scientific article published on 03 December 2021

Hypomethylation along with increased H19 expression in placentas from pregnancies complicated with fetal growth restriction

scientific article published on 03 December 2010

Hypomethylation and hypermethylation of DNA in Wilms tumors.

scientific article published in September 2002

Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.

scientific article

Identification of CD34+ cord blood cells and their subpopulations in preterm and term neonates using three-color flow cytometry.

scientific article published in January 1994

Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer

scientific article

Increased radiosensitivity by a combination of 9-cis-retinoic acid and interferon-y in breast cancer cells

scientific article published on 01 June 1996

Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies.

scientific article published on 6 April 2011

Integration of genetic and epigenetic markers for risk stratification: opportunities and challenges.

scientific article published on March 2016

Interaction of retinoic acid and interferon-alpha in breast cancer cell lines

scientific article published on 01 January 1996

Interleukin-12 heterodimer in the ascitic fluid of patients with ovarian cancer

scientific article published on 01 January 1999

Interleukin-3, interleukin-6, granulocyte-macrophage colony-stimulating factor and erythropoietin cord blood levels of preterm and term neonates

scientific article published on 01 July 1993

Intra-Gene DNA Methylation Variability Is a Clinically Independent Prognostic Marker in Women's Cancers

scientific article published on 2 December 2015

Loss of imprinting and aberrant methylation of IGF2 in placentas from pregnancies complicated with fetal growth restriction.

scientific article

Mechanism of cytokinesis failure in ovarian cystadenomas with defective BRCA1 and P53 pathways

scientific article published on 03 October 2018

Mechanism of synergistic action of all-trans- or 9-cis-retinoic acid and interferons in breast cancer cells

scientific article published on 01 December 1993

Methylated NEUROD1 promoter is a marker for chemosensitivity in breast cancer.

scientific article published in June 2008

Methylation patterns in serum DNA for early identification of disseminated breast cancer

scientific article published on 22 December 2017

Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer.

scientific article

Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer.

scientific article published on February 2004

Neopterin is an independent prognostic variable in females with breast cancer

scientific article published on 01 November 1999

New insights into p53 regulation and gene therapy for cancer.

scientific article

Non-Surgical Cancer Risk Reduction in BRCA1 Mutation Carriers: Disabling the Remote Control

scientific article published on 27 February 2020

Osteoprotegerin (OPG), The Endogenous Inhibitor of Receptor Activator of NF-κB Ligand (RANKL), is Dysregulated in BRCA Mutation Carriers

scientific article

Outcome of patients with advanced ovarian cancer who do not undergo debulking surgery: A single institution retrospective review.

scientific article published on 5 November 2016

Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.

scientific article published on 16 December 2015

Ovarian cancer symptoms, routes to diagnosis and survival - Population cohort study in the 'no screen' arm of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

scientific article published on 16 June 2020

PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer.

scientific article

PPM1D Mosaic Truncating Variants in Ovarian Cancer Cases May Be Treatment-Related Somatic Mutations

scientific article published on 27 January 2016

Paclitaxel- and docetaxel-dependent activation of CA-125 expression in human ovarian carcinoma cells

scientific article published on 01 September 1997

Peritoneal mesothelial cells as a significant source of ascitic immunostimulatory protein 90K

scientific article published on 01 November 2000

Personalized early detection and prevention of breast cancer: ENVISION consensus statement

scientific article published on 18 June 2020

Pre-eclampsia: a disorder of placental mitochondria?

scientific article published on 01 July 1998

Prediction models for endometrial cancer for the general population or symptomatic women: A systematic review

scientific article published on 31 March 2018

Pregnancy as a tissue expander in the correction of a scar deformity

scientific article published on 01 February 2004

Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer

scientific article

Prognostic gene expression signature for high-grade serous ovarian cancer

scientific article published on 27 May 2020

Psychosocial adversity and socioeconomic position during childhood and epigenetic age: analysis of two prospective cohort studies.

scientific article published on 22 January 2018

Publisher Correction: Personalized early detection and prevention of breast cancer: ENVISION consensus statement

scientific article published on 29 June 2020

Recruitment of newly diagnosed ovarian cancer patients proved challenging in a multicentre biobanking study.

scientific article published on 13 November 2010

Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening.

scientific article published on 11 May 2015

Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development

scientific journal article

Sensitivity of breast and ovarian cancer cells for interferons (IFNs) and retinoids

scientific article published on 01 April 1996

Serum oestrogen receptor alpha and beta bioactivity are independently associated with breast cancer: a proof of principle study.

scientific article published on 02 June 2009

Smoking in pregnancy

scientific article published on 01 October 1999

Stochastic epigenetic outliers can define field defects in cancer

scientific article

Switching from standard to dose-dense chemotherapy in front-line treatment of advanced ovarian cancer: a retrospective study of feasibility and efficacy.

scientific article published in January 2016

Systems-epigenomics inference of transcription factor activity implicates aryl-hydrocarbon-receptor inactivation as a key event in lung cancer development.

scientific article published on 20 December 2017

Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples.

scientific article published on 12 January 2017

The dynamics of DNA methylation covariation patterns in carcinogenesis.

scientific article

The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation

scientific article published on 14 September 2016

The multi-omic landscape of transcription factor inactivation in cancer

scientific article published on 25 August 2016

The natural history of endometrial polyps.

scientific article

The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer.

scientific article published on 22 December 2017

The potential prognostic, predictive, and therapeutic values of DNA methylation in cancer. Commentary re: J. Kwong et al., Promoter hypermethylation of multiple genes in nasopharyngeal carcinoma. Clin. Cancer Res., 8: 131-137, 2002, and H-Z. Zou et

scientific article published on 01 January 2002

The sex hormone system in carriers of BRCA1/2 mutations: a case-control study.

scientific article published on 17 October 2013

Time to diagnosis of Type I or II invasive epithelial ovarian cancers: a multicentre observational study using patient questionnaire and primary care records.

scientific article published on 29 May 2015

Toll-like receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors

scientific article

Use of IOTA simple rules for diagnosis of ovarian cancer: meta-analysis

scientific article

What do European women know about their female cancer risks and cancer screening? A cross-sectional online intervention survey in five European countries

scientific article published on 28 December 2018

Women's perception, attitudes, and intended behavior towards predictive epigenetic risk testing for female cancers in 5 European countries: a cross-sectional online survey

scientific article published on 30 May 2019

[Immunostimulating protein 90K in ovarian carcinoma]

scientific article published on 01 January 1996

[Interaction of interferon with retinoic acid]

scientific article published on 01 January 1994

[Prediction of preeclampsia:new hypotheses, new approaches]

scientific article published on 01 January 1998

[Tumorectomy in conscious patient with suspected pregnancy associated breast cancer under cervical epidural anesthesia]

scientific article published on 01 July 2004

hCDC4 gene mutations in endometrial cancer

scientific article (publication date: 15 August 2002)

p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article published on 22 March 2023

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