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List of works by Fernando Lecanda

A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis.

scientific article published on 13 March 2017

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma

scientific article

A gene signature of bone metastatic colonization sensitizes for tumor-induced osteolysis and predicts survival in lung cancer.

scientific article published on 28 October 2013

Abstract 4593: Genome-wide association study identifies novel loci associated with osteosarcoma

Abstract 5574: High prevalence of germline TP53 mutations in young osteosarcoma cases

Ae2(a,b)-deficient mice exhibit osteopetrosis of long bones but not of calvaria

scientific article published on 29 June 2009

An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer.

scientific article published on 21 February 2017

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Bone metastases in lung cancer. Potential novel approaches to therapy

scientific article published on July 2015

CYR61 downregulation reduces osteosarcoma cell invasion, migration, and metastasis.

scientific article published on July 2011

Calpain-6 is an endothelin-1 signaling dependent protective factor in chemoresistant osteosarcoma.

scientific article published on 16 August 2011

Changes in skeletal metabolism after the administration of demineralized bone proteins and fluoride

scientific article published on 01 September 1995

Cortactin (CTTN) overexpression in osteosarcoma correlates with advanced stage and reduced survival.

scientific article published in January 2011

Cyclic stretch enhances gap junctional communication between osteoblastic cells.

scientific article published in February 1998

Differential regulation of cadherins by dexamethasone in human osteoblastic cells

scientific article (publication date: April 2000)

Dose Volume Histogram Constraints in Patients with Head and Neck Cancer treated with Surgery and Adjuvant HDR Brachytherapy: A Proposal of the Head and Neck and Skin GEC ESTRO Working Group

scientific article published on 14 September 2020

EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth

scientific article published on 19 January 2017

ErbB3 silencing reduces osteosarcoma cell proliferation and tumor growth in vivo.

scientific article published on 27 March 2013

Gap Junctional Communication Modulates Gene Expression in Osteoblastic Cells ⬇️

scientific article published on August 1, 1998

Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters.

scientific article published on 16 April 2003

Genome-wide association study identifies two susceptibility loci for osteosarcoma

scientific article (publication date: July 2013)

Germline TP53 variants and susceptibility to osteosarcoma.

scientific article

Human osteoblasts express a repertoire of cadherins, which are critical for BMP-2-induced osteogenic differentiation.

scientific article published on April 1998

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Inhibition of collagen receptor discoidin domain receptor-1 (DDR1) reduces cell survival, homing, and colonization in lung cancer bone metastasis.

scientific article

Las metástasis óseas del cáncer

scientific article published on 01 May 2006

Microvesicles: Isolation, Characterization for In Vitro and In Vivo Procedures.

scientific article published in January 2016

Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16 and activation of the DNA damage response pathway

scientific article

New syngeneic inflammatory-related lung cancer metastatic model harboring double KRAS/WWOX alterations

scientific article published on 28 January 2014

Novel alternatively spliced ADAM8 isoforms contribute to the aggressive bone metastatic phenotype of lung cancer.

scientific article

Profiling of Chemonaive Osteosarcoma and Paired-Normal Cells Identifies EBF2 as a Mediator of Osteoprotegerin Inhibition to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis

scientific article published on 11 August 2009

Proliferation, differentiation and apoptosis in connexin43-null osteoblasts.

scientific article

RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner

scientific article published on 12 November 2013

Radiation effects on antitumor immune responses: current perspectives and challenges

scientific article published on 18 January 2018

Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2 ⬇️

scientific article published on December 1, 1997

Regulation of connexin43 expression and function by prostaglandin E2 (PGE2) and parathyroid hormone (PTH) in osteoblastic cells

scientific article published on 01 January 1998

Regulation of insulin-like growth factors I and II and their binding proteins in human bone marrow stromal cells by dexamethasone

scientific article published on 01 December 1998

Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1.

scientific article

Sphere-derived tumor cells exhibit impaired metastasis by a host-mediated quiescent phenotype.

scientific article

Targeting the E3 ubiquitin casitas B-lineage lymphoma decreases osteosarcoma cell growth and survival and reduces tumorigenesis ⬇️

scientific article published on October 1, 2012

The Usefulness of Bone Biomarkers for Monitoring Treatment Disease: A Comparative Study in Osteolytic and Osteosclerotic Bone Metastasis Models.

scientific article published on 16 February 2017

The oncolytic adenovirus Δ24-RGD in combination with cisplatin exerts a potent anti-osteosarcoma activity

scientific article published on October 2014

Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer

scientific article published on 01 May 2022

Tumor-stromal interactions of the bone microenvironment: in vitro findings and potential in vivo relevance in metastatic lung cancer models.

scientific article

Zinc chelation: a metallothionein 2A's mechanism of action involved in osteosarcoma cell death and chemotherapy resistance.

scientific article published on 24 October 2013

miRNA cargo within exosome-like vesicle transfer influences metastatic bone colonization.

scientific article published on 6 February 2014

ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis

scientific article published on 17 March 2016

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