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List of works by Andrea Fleig

A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity.

scientific article published on 11 January 2006

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

scientific article published in May 2001

Absence of Ca2+ current facilitation in skeletal muscle of transgenic mice lacking the type 1 ryanodine receptor

scientific article published on 01 October 1996

Activation of store-operated I(CRAC) by hydrogen peroxide.

scientific article

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

scientific article

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

scientific article

CRACM1 multimers form the ion-selective pore of the CRAC channel.

scientific article published on 14 September 2006

CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties.

scientific article published on 19 April 2007

CaT1 and the calcium release-activated calcium channel manifest distinct pore properties.

scientific article

Calcium release-activated calcium current (ICRAC) is a direct target for sphingosine

scientific article published on 01 September 1998

Cell cycle-dependent regulation of store-operated I(CRAC) and Mg2+-nucleotide-regulated MagNuM (TRPM7) currents.

scientific article published on 24 October 2006

Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes

scientific article

D-6-Deoxy-myo-inositol 1,3,4,5-tetrakisphosphate, a mimic of d-myo-inositol 1,3,4,5-tetrakisphosphate: biological activity and pH-dependent conformational properties.

scientific article published in August 2004

Dendritic cell maturation and chemotaxis is regulated by TRPM2‐mediated lysosomal Ca2+release ⬇️

scientific article published on July 13, 2011

Discrimination of intracellular calcium store subcompartments using TRPV1 (transient receptor potential channel, vanilloid subfamily member 1) release channel activity.

scientific article published on April 2003

Dual-function ion channel/protein kinases: novel components of vertebrate magnesium regulatory mechanisms.

scientific article published on 5 February 2004

Effects of clamp rise-time on rat brain IIA sodium channels in Xenopus oocytes.

scientific article published in May 1997

Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice.

scientific article published on 23 December 2014

Emerging roles of TRPM channels.

scientific article published on January 2004

Excessive repolarization-dependent calcium currents induced by strong depolarizations in rat skeletal myoballs

scientific article published on 01 November 1995

Human CNNM2 is not a Mg(2+) transporter per se.

scientific article published on 11 April 2016

IP(3) receptor subtype-dependent activation of store-operated calcium entry through I(CRAC).

scientific article

Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice

scientific article published on 15 August 2017

InsP4 facilitates store-operated calcium influx by inhibition of InsP3 5-phosphatase.

scientific article

Lipopolysaccharide-induced down-regulation of Ca2+ release-activated Ca2+ currents (I CRAC) but not Ca2+-activated TRPM4-like currents (I CAN) in cultured mouse microglial cells

scientific article published on 08 November 2007

N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation.

scientific article published on September 2014

New insights into Ca2+ channel function in health and disease

scientific article

Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes

scientific article published on 03 April 2006

Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion ⬇️

scientific article (publication date: 22 February 2017)

Point mutations in IIS4 alter activation and inactivation of rat brain IIA Na channels in Xenopus oocyte macropatches.

scientific article

Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain

scholarly article

Regulation of TRPM2 by extra- and intracellular calcium.

scientific article

Regulation of endogenous and heterologous Ca²⁺ release-activated Ca²⁺ currents by pH.

scientific article published on 2 August 2014

STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation

scientific article

Scalaradial Is a Potent Inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) Ion Channels.

scientific article published on 11 October 2017

Silent calcium channels generate excessive tail currents and facilitation of calcium currents in rat skeletal myoballs

scientific article published on 01 July 1996

Solute Carrier Family SLC41, what do we really know about it?

scientific article (publication date: 2013)

Store-operated calcium entry: a tough nut to CRAC.

scientific article published on 20 July 2004

TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLD

scientific article published on 23 February 2006

TRPM4 controls insulin secretion in pancreatic beta-cells

scientific journal article

TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization

scientific journal article

TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i

scientific article

TRPM5 regulates glucose-stimulated insulin secretion.

scientific article

TRPM7

scientific article

TRPM7 Regulates Axonal Outgrowth and Maturation of Primary Hippocampal Neurons

scientific article published on 11 December 2014

TRPM7 channel is regulated by magnesium nucleotides via its kinase domain.

scientific article

TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis

scientific article published on 03 August 2018

TRPM7 is regulated by halides through its kinase domain

scientific article published on 08 March 2013

TRPM7 kinase activity regulates murine mast cell degranulation.

scientific article published on 14 December 2015

TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

scientific article

TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells

scientific article published on 16 October 2013

The TRPM ion channel subfamily: molecular, biophysical and functional features.

scientific article

The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels

scientific article published on 02 January 2014

The TRPM7 channel kinase regulates store-operated calcium entry

scientific article

The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins.

scientific article published on 2 March 2018

The calcium-permeable non-selective cation channel TRPM2 is modulated by cellular acidification

scientific article published on 01 March 2010

The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity

scientific article published on 15 September 2016

The store-operated calcium current I(CRAC): nonlinear activation by InsP3 and dissociation from calcium release.

scientific article published in June 1997

Two novel 2-aminoethyl diphenylborinate (2-APB) analogues differentially activate and inhibit store-operated Ca(2+) entry via STIM proteins.

scientific article published on 27 November 2009

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