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List of works by Jennifer Pocock

A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia

scientific article published on 23 December 2019

A role for caspase-1 and -3 in the pathology of experimental allergic encephalomyelitis : inflammation versus degeneration

scientific article published on November 2002

Abrogation of LRRK2 dependent Rab10 phosphorylation with TLR4 activation and alterations in evoked cytokine release in immune cells

scientific article published on 15 May 2021

Activated microglia in Alzheimer's disease and stroke.

scientific article

Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up-regulated in Alzheimer's disease.

scientific article published in September 2002

Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity.

scientific article published in March 2003

Blockage of CR1 prevents activation of rodent microglia

scientific article published on 27 February 2013

Cannabinoids inhibit neurodegeneration in models of multiple sclerosis

scientific article published on 22 July 2003

Chromogranin A activates diverse pathways mediating inducible nitric oxide expression and apoptosis in primary microglia

scientific article published on 15 December 2006

Combined tissue and fluid proteomics with Tandem Mass Tags to identify low-abundance protein biomarkers of disease in peripheral body fluid: An Alzheimer's Disease case study

scientific article published on 4 November 2016

Complement receptor 1 (CR1) and Alzheimer's disease

scientific article published on 23 July 2011

Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis

scientific article published on 08 August 2018

Correction to: Wnt3a induces exosome secretion from primary cultured rat microglia

scientific article published on 06 March 2020

Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood-brain barrier damage

scientific article published on 2 February 2009

Emerging roles of p53 in glial cell function in health and disease.

scientific article

Endothelin-1 inhibits voltage-sensitive Ca2+ channels in cultured rat cerebellar granule neurones via the ET-A receptor.

scientific article published in October 1998

Energetics of cultured neurones and ischaemia ⬇️

scientific article published on November 1, 1994

Exocytotic and nonexocytotic modes of glutamate release from cultured cerebellar granule cells during chemical ischaemia.

scientific article

Glia: guardians, gluttons, or guides for the maintenance of neuronal connectivity?

scientific article

Glutamate exocytosis from cerebellar granule cells: The mechanism of a transition to an L-type Ca2+ channel coupling

scientific article published on 01 August 1995

Glutamate induces release of glutathione from cultured rat astrocytes--a possible neuroprotective mechanism?

scientific article published on 7 January 2008

Human Huntington's disease pluripotent stem cell-derived microglia develop normally but are abnormally hyper-reactive and release elevated levels of reactive oxygen species

scientific article published on 19 April 2021

Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis

scientific article published on 01 August 2018

Inhibiting p53 pathways in microglia attenuates microglial-evoked neurotoxicity following exposure to Alzheimer peptides

scientific article published on 6 November 2009

Insights into TREM2 biology by network analysis of human brain gene expression data

scientific article

Intracellular free Ca2+responses in electrically stimulated cerebellar granule cells

article

Microglia release activators of neuronal proliferation mediated by activation of mitogen-activated protein kinase, phosphatidylinositol-3-kinase/Akt and delta-Notch signalling cascades.

scientific article

Microglia, Alzheimer's disease, and complement

scientific article published on 21 August 2012

Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease.

scientific article

Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial–neuronal interactions ⬇️

scientific article published on March 13, 2012

Microglial p53 activation is detrimental to neuronal synapses during activation-induced inflammation: Implications for neurodegeneration.

scientific article published on 7 September 2014

Microglial secreted cathepsin B induces neuronal apoptosis.

scientific article

Microglial signalling cascades in neurodegenerative disease.

scientific article

Modelling microglial function with induced pluripotent stem cells: an update

scientific article published on 01 August 2018

Modulation of ion gradients and glutamate release in cultured cerebellar granule cells by ouabain

scientific article published on 01 May 1995

Myelin-induced microglial neurotoxicity can be controlled by microglial metabotropic glutamate receptors.

scientific article published in July 2008

Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autoimmune CNS disease

scientific journal article

Neuroprotection by safinamide in the 6-hydroxydopamine model of Parkinson's disease

scientific article

Neurotransmitter receptors on microglia.

scientific article published on 29 September 2007

Nitric oxide (NO.) and the nitrosonium cation (NO+) reduce mitochondrial membrane potential and trigger apoptosis in neuronal PC12 cells

scientific article published on 01 November 1998

Phosphorylation of synapsin I and MARCKS in nerve terminals is mediated by Ca2+ entry via an Aga-GI sensitive Ca2+ channel which is coupled to glutamate exocytosis

scientific article published on 01 October 1994

Positive allosteric modulation of metabotropic glutamate receptor 5 down-regulates fibrinogen-activated microglia providing neuronal protection ⬇️

scientific article published on October 8, 2011

Pure albumin is a potent trigger of calcium signalling and proliferation in microglia but not macrophages or astrocytes.

scientific article published on March 2005

Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis.

scientific article published on 20 March 2013

Scavenger receptor control of chromogranin A-induced microglial stress and neurotoxic cascades.

scientific article published on 2 October 2009

Selective Depletion of Microglia from Cerebellar Granule Cell Cultures Using L-leucine Methyl Ester.

scientific article published on 7 July 2015

Soluble Fibrinogen Triggers Non-cell Autonomous ER Stress-Mediated Microglial-Induced Neurotoxicity

scientific article published on 19 November 2018

Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand.

scientific article

TREM2 Variants in Alzheimer's Disease ⬇️

scientific article published on November 14, 2012

The Plant-Derived Chalcone 2,2',5'-Trihydroxychalcone Provides Neuroprotection against Toll-Like Receptor 4 Triggered Inflammation in Microglia

scientific article

The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans

scholarly article by Xianyuan Xiang published in September 2018

The calcium channel coupled to the exocytosis of l-glutamate from cerebellar granule cells is inhibited by the spider toxin, Aga-GI

scientific article published on 01 November 1993

Wnt3a induces exosome secretion from primary cultured rat microglia.

scientific article

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