Search filters

List of works by Kenji Hashimoto

(+)-3-[2-(Benzo[b]thiophen-2-yl)-2-oxoethyl]-1-azabicyclo[2.2.2]octane as potent agonists for the alpha7 nicotinic acetylcholine receptor.

scientific article

(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice

scientific article published on 03 May 2018

(R)-Ketamine Rapidly Ameliorates the Decreased Spine Density in the Medial Prefrontal Cortex and Hippocampus of Susceptible Mice After Chronic Social Defeat Stress

scientific article published on 01 October 2019

(R)-Ketamine Shows Greater Potency and Longer Lasting Antidepressant Effects Than Its Metabolite (2R,6R)-Hydroxynorketamine.

scientific article published on 23 December 2016

3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-induced egr-1 mRNA in rat brain: pharmacological manipulation.

scientific article

4-Bromo-6-nitroquipazine: a new ligand for studying 5-hydroxytryptamine uptake sites in vivo

scientific article published on September 1, 1992

5-Hydroxytryptamine-independent antidepressant actions of (R)-ketamine in a chronic social defeat stress model

scientific article

7,8-Dihydroxyflavone, a TrkB agonist, attenuates behavioral abnormalities and neurotoxicity in mice after administration of methamphetamine.

scientific article

A BDNF Val66Met Polymorphism and Ketamine-induced Rapid Antidepressant Action

scientific article published on 30 April 2012

A case of methamphetamine use disorder treated with the antibiotic drug minocycline ⬇️

scientific article published on January 21, 2010

A functional glutathione S-transferase P1 gene polymorphism is associated with methamphetamine-induced psychosis in Japanese population

scientific article

A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder

scientific article published on 24 January 2017

A historical review of antidepressant effects of ketamine and its enantiomers

scientific article published on 05 February 2020

A key role of the subdiaphragmatic vagus nerve in the depression-like phenotype and abnormal composition of gut microbiota in mice after lipopolysaccharide administration

scientific article published on 09 June 2020

A pilot double-blind comparison of d-serine and high-dose olanzapine in treatment-resistant patients with schizophrenia

scientific article published on 02 October 2013

A retrospective study of the impact of age on patterns of care for elderly patients with metastatic breast cancer.

scientific article published on 31 March 2010

A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression-like phenotypes

scientific article published on 08 January 2021

A series of D-amino acid oxidase inhibitors specifically prevents and reverses formalin-induced tonic pain in rats.

scientific article published on 15 October 2010

A study of remitted and treatment-resistant depression using MMPI and including pessimism and optimism scales.

scientific article

AMPA Receptor Activation-Independent Antidepressant Actions of Ketamine Metabolite (S)-Norketamine

scientific article published on 14 May 2018

Abnormal composition of gut microbiota contributes to delirium-like behaviors after abdominal surgery in mice.

scientific article published on 24 January 2019

Abnormal composition of gut microbiota is associated with resilience versus susceptibility to inescapable electric stress

scientific article published on 17 September 2019

Abnormalities in the brain-immune system in psychotic disorders: from pathogenesis to prevention

scientific article published on 7 June 2017

Abnormalities of the glutamine-glutamate-GABA cycle in the schizophrenia brain.

scientific article published on 5 May 2014

Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study

scientific article published on March 2016

Abnormality in serum levels of mature brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in mood-stabilized patients with bipolar disorder: a study of two independent cohorts

scientific article published on 24 February 2014

Abnormality of cerebral perfusion in the posterior cingulate gyrus of a refractory patient with schizophrenia and minocycline treatment.

scientific article published on 28 April 2010

Activation of sigma-1 receptor chaperone in the treatment of neuropsychiatric diseases and its clinical implication

scientific article

Acute and repeated administration of the selective 5-HT(2A) receptor antagonist M100907 significantly alters the activity of midbrain dopamine neurons: an in vivo electrophysiological study.

scientific article

Acute effect of c-fos antisense oligodeoxynucleotide on hippocampal partial seizures elicited by electrical stimulation in rats.

scientific article

Adenosine A1 Receptor Agonists Block the Neuropathological Changes in Rat Retrosplenial Cortex after Administration of the NMDA Receptor Antagonist Dizocilpine ⬇️

scientific article published on March 1, 2004

Adjunctive treatment of brexpiprazole with fluoxetine shows a rapid antidepressant effect in social defeat stress model: Role of BDNF-TrkB signaling.

scientific article

Alteration of Plasma Glutamate and Glutamine Levels in Children with High-Functioning Autism ⬇️

scientific article published on October 5, 2011

Alterations in amino acid levels in mouse brain regions after adjunctive treatment of brexpiprazole with fluoxetine: comparison with (R)-ketamine.

scientific article

Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist.

scientific article

Alterations in glutamatergic signaling in the brain of dopamine supersensitivity psychosis and non-supersensitivity psychosis model rats.

scientific article

Alterations in the inflammatory cytokines and brain-derived neurotrophic factor contribute to depression-like phenotype after spared nerve injury: improvement by ketamine

scientific article

Alterations of the daily rhythms of HPT axis induced by chronic unpredicted mild stress in rats.

scientific article published on 15 June 2014

Altered dendritic morphology of Purkinje cells in Dyt1 ΔGAG knock-in and purkinje cell-specific Dyt1 conditional knockout mice.

scientific article

Altered expression of BDNF, BDNF pro-peptide and their precursor proBDNF in brain and liver tissues from psychiatric disorders: rethinking the brain-liver axis.

scientific article published on 16 May 2017

Amantadine induces c-fos in rat striatum: reversal with dopamine D1 and NMDA receptor antagonists.

scientific article published in October 1995

An update on ketamine and its two enantiomers as rapid-acting antidepressants

scientific article published on 4 December 2018

Analysis of correlation between serum D-serine levels and functional promoter polymorphisms of GRIN2A and GRIN2B genes.

scientific article published on 2 November 2005

Analysis of strain‐dependent prepulse inhibition points to a role for Shmt1 (SHMT1) in mice and in schizophrenia ⬇️

scientific article published on October 26, 2010

Antagonism of 3,4-methylenedioxymethamphetamine-induced neurotoxicity in rat brain by 1-piperonylpiperazine

scientific article published on September 1, 1992

Antibiotic-induced microbiome depletion is associated with resilience in mice after chronic social defeat stress

scientific article published on 13 September 2019

Antibiotic-induced microbiome depletion protects against MPTP-induced dopaminergic neurotoxicity in the brain

scientific article published on 03 September 2019

Antidepressant Effects of (+)-MK-801 and (-)-MK-801 in the Social Defeat Stress Model.

scientific article published on 08 September 2016

Antidepressant Effects of Ketamine on Depression-like Behavior in Juvenile Mice after Neonatal Dexamethasone Exposure.

scientific article

Antidepressant Potential of (R)-Ketamine in Rodent Models: Comparison with (S)-Ketamine.

scientific article published on 23 January 2017

Antidepressant effects of TBE-31 and MCE-1, the novel Nrf2 activators, in an inflammation model of depression

scientific article published in November 2016

Antidepressant effects of TrkB ligands on depression-like behavior and dendritic changes in mice after inflammation

scientific article

Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation.

scientific article published on 15 November 2016

Antipsychotic-like effects of a novel phosphodiesterase 10A inhibitor T-251 in rodents

scientific article published on 09 August 2019

Are NMDA and opioid receptors involved in the antidepressant actions of ketamine?

scientific article published on 19 May 2020

Association analyses between brain-expressed fatty-acid binding protein (FABP) genes and schizophrenia and bipolar disorder.

scientific article

Association between angiotensin I-converting enzyme insertion/deletion gene functional polymorphism and novelty seeking personality in healthy females.

scientific article published on 19 October 2005

Association between serum levels of glial cell-line derived neurotrophic factor and attention deficits in schizophrenia.

scientific article published on 24 May 2014

Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophrenia.

scientific article published on 5 February 2009

Association study between brain-derived neurotrophic factor gene polymorphisms and methamphetamine abusers in Japan.

scientific article published in January 2005

Association study between polymorphisms in glutathione-related genes and methamphetamine use disorder in a Japanese population

scientific article

Association study between the PIK4CA gene and methamphetamine use disorder in a Japanese population

scientific article published in March 2009

Auditory-conditioned-fear-dependent c-Fos expression is altered in the emotion-related brain structures of Fyn-deficient mice.

scientific article published in November 2004

Author Correction: Lack of metabolism in (R)-ketamine's antidepressant actions in a chronic social defeat stress model.

scientific article published on 12 July 2018

BDNF and proBDNF as biomarkers for bipolar disorder.

scientific article

BDNF variant linked to anxiety-related behaviors.

scientific article published on February 2007

BDNF-TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms

scientific article

Behavioral changes and expression of heat shock protein hsp-70 mRNA, brain-derived neurotrophic factor mRNA, and cyclooxygenase-2 mRNA in rat brain following seizures induced by systemic administration of kainic acid.

scientific article published in September 1998

Benefical effects of sigma-1 agonist fluvoxamine for tardive dyskinesia and tardive akathisia in patients with schizophrenia: report of three cases

scientific article published on 24 October 2013

Beneficial effects of (R)-ketamine, but not its metabolite (2R,6R)-hydroxynorketamine, in the depression-like phenotype, inflammatory bone markers, and bone mineral density in a chronic social defeat stress model

scientific article published on 11 April 2019

Beneficial effects of anti-RANKL antibody in depression-like phenotype, inflammatory bone markers, and bone mineral density in male susceptible mice after chronic social defeat stress

scientific article published on 29 November 2019

Beneficial effects of the sigma-1 agonist fluvoxamine for tardive dyskinesia in patients with postpsychotic depressive disorder of schizophrenia: report of 5 cases.

scientific article published on 8 November 2012

Bifidobacterium in the gut microbiota confer resilience to chronic social defeat stress in mice.

scientific article published on 03 April 2017

Biodistribution and radiation dosimetry of the α7 nicotinic acetylcholine receptor ligand [11C]CHIBA-1001 in humans.

scientific article published on 3 December 2010

Biomarkers for Alzheimer's disease: from pathogenesis to drug development

scientific article published on 01 August 2018

Blepharospasm associated with olanzapine: a case report.

scientific article published in September 2004

Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut-microbiota-brain axis

scientific article

Blood D-serine levels as a predictive biomarker for the rapid antidepressant effects of the NMDA receptor antagonist ketamine

scientific article published on 5 September 2014

Brain-derived Neurotrophic Factor (BDNF)-TrkB Signaling in Inflammation-related Depression and Potential Therapeutic Targets

scientific article published on 18 January 2016

Brain-derived neurotrophic factor (BDNF) and its precursor proBDNF as diagnostic biomarkers for major depressive disorder and bipolar disorder.

scientific article

Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions.

scientific article

Brain-derived neurotrophic factor-TrkB signaling and the mechanism of antidepressant activity by ketamine in mood disorders

scientific article published on 01 March 2020

Brain-derived neurotrophic factor-TrkB signaling in the medial prefrontal cortex plays a role in the anhedonia-like phenotype after spared nerve injury.

scientific article

Can minocycline prevent the onset of Alzheimer's disease? ⬇️

scientific article published on March 17, 2011

Can the sigma-1 receptor agonist fluvoxamine prevent schizophrenia?

scientific article published on December 2009

Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis.

scientific article

Chronic Treatment With Aripiprazole Prevents Development of Dopamine Supersensitivity and Potentially Supersensitivity Psychosis ⬇️

scientific article published on March 14, 2011

Clinical outcomes of adult and childhood rhabdomyosarcoma treated with vincristine, d-actinomycin, and cyclophosphamide chemotherapy

scientific article published on 23 March 2012

Cognitive Impairment That Is Induced by (R)-Ketamine Is Abolished in NMDA GluN2D Receptor Subunit Knockout Mice

scientific article published on 01 July 2019

Combination of Nitrous Oxide with Isoflurane or Scopolamine for Treatment-resistant Major Depression.

scientific article published on April 2015

Combined intoxication with methylone and 5-MeO-MIPT.

scientific article

Comments on "An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606 in patients with treatment-refractory major depressive disorder".

scientific article published in August 2009

Comments on 'The effect of risperidone on D-amino acid oxidase activity as a hypothesis for a novel mechanism of action in the treatment of schizophrenia'.

scientific article published on 25 November 2009

Comparative evaluation of two serotonin transporter ligands in the human brain: [(11)C](+)McN5652 and [(11)C]cyanoimipramine.

scientific article published on 27 July 2002

Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model.

scientific article

Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression

scientific article

Comparison of antidepressant and side effects in mice after intranasal administration of (R,S)-ketamine, (R)-ketamine, and (S)-ketamine

scientific article published on 26 April 2019

Comparison of dose intensity of vincristine, d-actinomycin, and cyclophosphamide chemotherapy for child and adult rhabdomyosarcoma: a retrospective analysis.

scientific article published on 18 July 2012

Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression.

scientific article

Comparison of rapid and long-lasting antidepressant effects of negative modulators of α5-containing GABA receptors and (R)‑ketamine in a chronic social defeat stress model

article

Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia part II: Cognition, neuroimaging and genetics

scientific article

Criterion and construct validity of the CogState Schizophrenia Battery in Japanese patients with schizophrenia

scientific article (publication date: 2011)

Critical role of brain-derived neurotrophic factor in mood disorders

scientific article published on 01 May 2004

Cytochrome P450 derived epoxidized fatty acids as a therapeutic tool against neuroinflammatory diseases

scientific article published on 05 November 2019

Decreased bone mineral density in ovariectomized mice is ameliorated after subsequent repeated intermittent administration of (R)-ketamine, but not (S)-ketamine

scientific article published on 19 August 2020

Decreased cell proliferation in the dentate gyrus of alpha 7 nicotinic acetylcholine receptor heterozygous mice.

scientific article published in May 2004

Decreased expression of reelin receptor VLDLR in peripheral lymphocytes of drug-naive schizophrenic patients

scientific article

Decreased levels of free D-aspartic acid in the forebrain of serine racemase (Srr) knock-out mice.

scientific article

Decreased levels of serum brain-derived neurotrophic factor in female patients with eating disorders.

scientific article published in August 2003

Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia.

scientific article

Decreased serum levels of brain-derived neurotrophic factor in schizophrenic patients with deficit syndrome

scientific article

Decreased serum levels of epidermal growth factor in adult subjects with high-functioning autism

scientific article published on 21 November 2006

Decreased serum levels of hepatocyte growth factor in male adults with high-functioning autism.

scientific article published on 8 December 2006

Decreased serum levels of platelet-endothelial adhesion molecule (PECAM-1) in subjects with high-functioning autism: a negative correlation with head circumference at birth.

scientific article published on 23 May 2007

Decreased serum levels of transforming growth factor-beta1 in patients with autism

scientific article published on 6 October 2006

Decreased susceptibility to seizures induced by pentylenetetrazole in serine racemase knockout mice ⬇️

scientific article published on June 27, 2012

Deficits in emotion based decision-making in schizophrenia; a new insight based on the Iowa Gambling Task.

scientific article published on 24 October 2014

Deleterious effects of nervous system in the offspring following maternal SARS-CoV-2 infection during the COVID-19 pandemic

scientific article published in 2022

Deletion of serine racemase confers D-serine -dependent resilience to chronic social defeat stress

scientific article published on 14 March 2018

Depression-like phenotype by deletion of α7 nicotinic acetylcholine receptor: Role of BDNF-TrkB in nucleus accumbens.

scientific article

Depressive-like behavior in adrenocorticotropic hormone-treated rats blocked by memantine.

scientific article published on 17 May 2012

Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids

scientific article published on 30 September 2006

Detrimental Side Effects of Repeated Ketamine Infusions in the Brain.

scientific article published in October 2016

Dietary glucoraphanin prevents the onset of psychosis in the adult offspring after maternal immune activation.

scientific article published in February 2018

Dietary intake of glucoraphanin during pregnancy and lactation prevents the behavioral abnormalities in the offspring after maternal immune activation

scientific article published on 28 May 2020

Dietary intake of glucoraphanin prevents the reduction of dopamine transporter in the mouse striatum after repeated administration of MPTP

scientific article published on 27 May 2019

Dietary restriction changes behaviours in brain-derived neurotrophic factor heterozygous mice: role of serotonergic system.

scientific article published in October 2006

Differences between Japan and Taiwan in the treatment of pregnant women with depressive symptoms by omega-3 fatty acids: An open-label pilot study.

scientific article

Differential levels of brain amino acids in rat models presenting learned helplessness or non-learned helplessness ⬇️

scientific article published on April 9, 2013

Disruption of reelin signaling attenuates methamphetamine-induced hyperlocomotion

scientific article

Dizocilpine-induced neuropathological changes in rat retrosplenial cortex are reversed by subsequent clozapine treatment

scientific article published on 01 February 2000

Docosahexaenoic acid for selective prevention of posttraumatic stress disorder among severely injured patients: a randomized, placebo-controlled trial.

scientific article published on August 2015

Drug effects on distribution of [3H]3,4-methylenedioxymethamphetamine in mice.

scientific article published in April 1993

Dynamic changes in AP-1 transcription factor DNA binding activity in rat brain following administration of antidepressant amitriptyline and brain-derived neurotrophic factor.

scientific article published on August 2003

Early Intervention for Psychosis with N-Methyl-D-Aspartate Receptor Modulators.

scientific article published in December 2015

Editorial: Cognitive Enhancement in Psychiatric Disorders

scientific article published on 19 June 2019

Editorial: Glutamate-Related Biomarkers for Neuropsychiatric Disorders

scientific article published on 05 December 2019

Effect of antioxidant N-acetyl-L-cysteine on behavioral changes and neurotoxicity in rats after administration of methamphetamine.

scientific article published in July 2004

Effect of the acute and chronic administration of the putative atypical antipsychotic drug Y-931 (8-fluoro-12- (4-methylpiperazin-1-yl)-6H-[1]benzothieno[2,3b][1,5] benzodiazepine maleate) on spontaneously active rat midbrain dopamine neurons: an in

scientific article published in January 2004

Effect of the acute and chronic administration of the selective 5-HT6 receptor antagonist SB-271046 on the activity of midbrain dopamine neurons in rats: an in vivo electrophysiological study.

scientific article

Effects of AS2586114, a soluble epoxide hydrolase inhibitor, on hyperlocomotion and prepulse inhibition deficits in mice after administration of phencyclidine ⬇️

scientific article published on June 20, 2013

Effects of Brilliant Blue G on Serum Tumor Necrosis Factor-α Levels and Depression-like Behavior in Mice after Lipopolysaccharide Administration.

scientific article published on 24 April 2014

Effects of N-acetyl-L-cysteine on the reduction of brain dopamine transporters in monkey treated with methamphetamine.

scientific article published in October 2004

Effects of TrkB agonist 7,8-dihydroxyflavone on sensory gating deficits in mice after administration of methamphetamine.

scientific article published on 6 April 2013

Effects of a single bilateral infusion of R-ketamine in the rat brain regions of a learned helplessness model of depression

scientific article published in August 2016

Effects of add-on cilostazol on cognition in patients with schizophrenia: an open-label pilot trial

scientific article published on 01 October 2011

Effects of add-on tipepidine on treatment-resistant depression: an open-label pilot trial.

scientific article published on 20 July 2015

Effects of age and gender on the expression of brain-derived neurotrophic factor mRNA in rat retrosplenial cortex following administration of dizocilpine.

scientific article

Effects of amycenone on serum levels of tumor necrosis factor-α, interleukin-10, and depression-like behavior in mice after lipopolysaccharide administration.

scientific article published on 3 July 2015

Effects of antidepressants on alternations in serum cytokines and depressive-like behavior in mice after lipopolysaccharide administration.

scientific article published on 19 December 2012

Effects of antipsychotic drugs on neurotoxicity, expression of fos-like protein and c-fos mRNA in the retrosplenial cortex after administration of dizocilpine

scientific article published on 01 June 2000

Effects of aripiprazole on MK-801-induced prepulse inhibition deficits and mitogen-activated protein kinase signal transduction pathway.

scientific article published on 18 January 2010

Effects of benzylpiperazine derivatives on the neurotoxicity of 3,4-methylenedioxymethamphetamine in rat brain

scientific article published on September 11, 1992

Effects of brexpiprazole, a novel serotonin-dopamine activity modulator, on phencyclidine-induced cognitive deficits in mice: a role for serotonin 5-HT1A receptors

scientific article published on 20 June 2014

Effects of escitalopram, R-citalopram, and reboxetine on serum levels of tumor necrosis factor-α, interleukin-10, and depression-like behavior in mice after lipopolysaccharide administration

scientific article published on 15 February 2016

Effects of sodium benzoate on pre-pulse inhibition deficits and hyperlocomotion in mice after administration of phencyclidine.

scientific article published on 4 February 2015

Effects of the antioxidant sulforaphane on hyperlocomotion and prepulse inhibition deficits in mice after phencyclidine administration.

scientific article

Efficacy of anticonvulsant ethosuximide for major depressive disorder: a randomized, placebo-control clinical trial

scientific article published on 01 February 2020

Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients

scientific article

Emerging role of glutamate in the pathophysiology of major depressive disorder.

scientific article published on 28 May 2009

Enhancement of acoustic prepulse inhibition by contextual fear conditioning in mice is maintained even after contextual fear extinction.

scientific article published on 14 November 2009

Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism ⬇️

scientific article published on March 26, 2013

Erratum: figure correction

scientific article published on 01 December 2014

Essential Role of Keap1-Nrf2 Signaling in Mood Disorders: Overview and Future Perspective

scientific article published on 16 October 2018

Essential role of microglial transforming growth factor-β1 in antidepressant actions of (R)-ketamine and the novel antidepressant TGF-β1

scientific article published on 27 January 2020

Ethnic differences in the serum levels of proBDNF, a precursor of brain-derived neurotrophic factor (BDNF), in mood disorders.

scientific article published on 4 September 2015

Evaluating the cognitive decline in early-stage frontotemporal dementia

scientific article published on 15 May 2009

Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology

scientific article published on 28 October 2019

Expression of Fos protein in rat brain following administration of a nicotinic acetylcholine receptor agonist epibatidine ⬇️

scientific article published on June 22, 1998

Expression of brain-derived neurotrophic factor (BDNF) mRNA in rat retrosplenial cortex following administration of phencyclidine.

scientific article

Expression of cyclooxygenase-2 mRNA in rat retrosplenial cortex following administration of phencyclidine ⬇️

scientific article published on July 11, 1997

Expression of heat shock protein HSP-70 in the retrosplenial cortex of rat brain after administration of (R,S)-ketamine and (S)-ketamine, but not (R)-ketamine

scientific article published on 17 July 2018

Factors that affect the duration of the interval between the completion of palliative chemotherapy and death

scientific article published on 11 July 2009

Failure to confirm the association between the PIK4CA gene and schizophrenia in a Japanese population

scientific article published on 01 April 2009

Fecal microbiota transplantation from patients with rheumatoid arthritis causes depression-like behaviors in mice through abnormal T cells activation

scientific article published on 01 June 2022

Fluvoxamine for blonanserin-associated akathisia in patients with schizophrenia: report of five cases.

scientific article

Fluvoxamine improved cognitive impairments in a patient with schizophrenia.

scientific article published on 19 June 2010

Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra-high risk of psychotic disorder.

scientific article published on 30 September 2011

Functional polymorphism of the NQO2 gene is associated with methamphetamine psychosis.

scientific article

Further analysis of microsatellite marker in the BDNF gene.

scientific article published in May 2005

Further characterization of [3H]ifenprodil binding in rat brain.

scientific article published in January 1994

G protein-coupled receptor kinase 6/β-arrestin 2 system in a rat model of dopamine supersensitivity psychosis

scientific article published on 14 July 2015

Gamma-band auditory steady-state response is associated with plasma levels of d-serine in schizophrenia: An exploratory study

scientific article published on 25 February 2019

Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress.

scientific article published on 14 March 2016

Genetic association between G protein-coupled receptor kinase 6/β-arrestin 2 and dopamine supersensitivity psychosis in schizophrenia

scientific article published on 29 July 2015

Genetic examination of the PLXNA2 gene in Japanese and Chinese people with schizophrenia.

scientific article published on 11 December 2007

Genomic Triplication of the Glycine Decarboxylase Gene and N-Methyl-D-Aspartate Receptor Hypofunction: Improvement by Glycine and D-Cycloserine

scientific article published on 01 October 2019

Glutamate Signaling in Synaptogenesis and NMDA Receptors as Potential Therapeutic Targets for Psychiatric Disorders

scientific article published on January 2015

Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders.

scientific article

Glutamatergic system abnormalities in posttraumatic stress disorder

scientific article published on 22 August 2015

Glycine Transporter-1: A New Potential Therapeutic Target for Schizophrenia ⬇️

scientific article published on January 1, 2011

Glycine transporter inhibitors as therapeutic agents for schizophrenia.

scientific article published on January 2006

Glyphosate exposure exacerbates the dopaminergic neurotoxicity in the mouse brain after repeated administration of MPTP

scientific article published on 06 May 2020

Hematologic safety of breast cancer chemotherapies in patients with hepatitis B or C virus infection

scientific article

High occupancy of sigma-1 receptors in the human brain after single oral administration of fluvoxamine: a positron emission tomography study using [11C]SA4503.

scientific article published on 30 July 2007

High occupancy of sigma1 receptors in the human brain after single oral administration of donepezil: a positron emission tomography study using [11C]SA4503.

scientific article published on 2 July 2009

High-affinity [3H]6-nitroquipazine binding sites in rat brain ⬇️

scientific article published on May 16, 1990

High-affinity [3H]6-nitroquipazine binding to the 5-hydroxytryptamine transport system in rat lung ⬇️

scientific article published on June 1, 1991

Identification of functional polymorphisms in the promoter region of the human PICK1 gene and their association with methamphetamine psychosis

scientific article published on 01 July 2007

Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels

scientific article

Ifenprodil for the Treatment of Flashbacks in Female Posttraumatic Stress Disorder Patients with a History of Childhood Sexual Abuse ⬇️

scientific article published on November 8, 2011

Ifenprodil for the treatment of flashbacks in adolescent female posttraumatic stress disorder patients with a history of abuse.

scientific article published on 9 August 2013

Immune activation during pregnancy in mice leads to dopaminergic hyperfunction and cognitive impairment in the offspring: a neurodevelopmental animal model of schizophrenia.

scientific article published on 26 October 2005

Immunohistochemical profile for unknown primary adenocarcinoma

scientific article

Impact of FAAH gene, hyperactivation in emotion processing brain regions and Lavender oil preparation Silexan in anxiety

scientific article published on 01 March 2019

Impact of aerobic exercise on cognitive impairment and oxidative stress markers in methamphetamine-dependent patients

scientific article published on 17 March 2018

Impact of age on optimal dose of antidepressants

scientific article published on 03 January 2020

Impact of consuming green and yellow vegetables on the depressive symptoms of junior and senior high school students in Japan

scientific article published on 07 February 2019

Impact of serotonin transporter gene on rTMS augmentation of SSRIs for obsessive compulsive disorder

scientific article published on 02 July 2019

Impaired processing speed and attention in first-episode drug naive schizophrenia with deficit syndrome.

scientific article published on 30 September 2014

Impaired visual, working, and verbal memory in first-episode, drug-naive patients with major depressive disorder in a Chinese population.

scientific article published on 23 April 2018

Improvement of dizocilpine-induced social recognition deficits in mice by brexpiprazole, a novel serotonin-dopamine activity modulator

scientific article published on 5 January 2015

In Vivo Evaluation of (11)C-labeled Three Radioligands for Glycine Transporter 1 in the Mouse Brain

scientific article published on 30 April 2012

In vivo evaluation of alpha7 nicotinic acetylcholine receptor agonists [11C]A-582941 and [11C]A-844606 in mice and conscious monkeys

scientific article

In vivo evaluation of carbon-11-labelled non-sarcosine-based glycine transporter 1 inhibitors in mice and conscious monkeys.

scientific article published on 4 February 2011

In vivo regulation of serotonin 5-HT2A receptors in rat brain by subchronic administration of sigma receptor ligand NE-100

scientific article published on 01 January 1997

Increased BDNF-TrkB signaling in the nucleus accumbens plays a role in the risk for psychosis after cannabis exposure during adolescence

scientific article published on 08 January 2019

Increased EphA4-ephexin1 signaling in the medial prefrontal cortex plays a role in depression-like phenotype.

scientific article published on 2 August 2017

Increased Levels of C1q in the Prefrontal Cortex of Adult Offspring after Maternal Immune Activation: Prevention by 7,8-Dihydroxyflavone.

scientific article published on February 2017

Increased expression of inwardly rectifying Kir4.1 channel in the parietal cortex from patients with major depressive disorder

scientific article published on 05 November 2018

Increased levels of ascorbic acid in the cerebrospinal fluid of cognitively intact elderly patients with major depression: a preliminary study

scientific article

Increased levels of glutamate in brains from patients with mood disorders.

scientific article published on 15 June 2007

Increased levels of serum basic fibroblast growth factor in schizophrenia.

scientific article

Increased midkine levels in sera from patients with Alzheimer's disease.

scientific article published in May 2005

Increased serum G72 protein levels in patients with schizophrenia: a potential candidate biomarker

scientific article published on 14 July 2016

Increased serum levels of apoptosis in deficit syndrome schizophrenia patients: a preliminary study

scientific article published on 23 May 2016

Increased serum levels of glutamate in adult patients with autism.

scientific article

Induction of Fos protein by 3,4- methylenedioxymethamphetamine (Ecstasy) in rat brain: regional differences in pharmacological manipulation.

scientific article

Induction of heat shock protein (HSP)-70 in posterior cingulate and retrosplenial cortex of rat brain by dizocilpine and phencyclidine: lack of protective effects of sigma receptor ligands

scientific article published on 01 January 1996

Induction of heat shock protein HSP-70 in rat retrosplenial cortex following administration of dextromethorphan.

scientific article

Inflammatory biomarkers as differential predictors of antidepressant response

scientific article

Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain–gut–microbiota axis via the subdiaphragmatic vagus nerve

scientific article published on 11 June 2021

Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve

scientific article published on 15 August 2020

Intake of 7,8-Dihydroxyflavone During Juvenile and Adolescent Stages Prevents Onset of Psychosis in Adult Offspring After Maternal Immune Activation

scientific article

Intake of 7,8-dihydroxyflavone from pregnancy to weaning prevents cognitive deficits in adult offspring after maternal immune activation.

scientific article

Interaction of new antidepressants with sigma-1 receptor chaperones and their potentiation of neurite outgrowth in PC12 cells.

scientific article published on 5 February 2014

Interactions of erythro-ifenprodil, threo-ifenprodil, erythro-iodoifenprodil, and eliprodil with subtypes of sigma receptors

scientific article published on 01 February 1995

Interactions of the potent D-amino acid oxidase inhibitor CBIO with morphine in pain and tolerance to analgesia

scientific article published on 02 May 2012

Investigation of betaine as a novel psychotherapeutic for schizophrenia

scientific article published on 26 June 2019

Irradiation in adulthood as a new model of schizophrenia.

scientific article published on 28 May 2008

Is (S)-norketamine an alternative antidepressant for esketamine?

scientific article published on 14 July 2018

Is D-cycloserine a prodrug for D-serine in the brain?

scientific article published on 9 August 2012

Isotopic Fractionation of Iproniazid and Isopropylhydrazine from Their Deuterated Analogues and Application for Isotope Dilution Analysis by Capillary Gas Chromatography ⬇️

scientific article published on 01 October 1991

Keap1-Nrf2 signaling pathway confers resilience versus susceptibility to inescapable electric stress.

scientific article published on 8 November 2017

Ketamine's antidepressant action: beyond NMDA receptor inhibition

scientific article

Key role of gut microbiota in anhedonia-like phenotype in rodents with neuropathic pain

scientific article published on 31 January 2019

Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation

scientific article published on 19 March 2019

Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine

scientific article

Lack of Antidepressant Effects of Low-Voltage-Sensitive T-Type Calcium Channel Blocker Ethosuximide in a Chronic Social Defeat Stress Model: Comparison with (R)-Ketamine

scientific article published on 01 November 2018

Lack of Opioid System in the Antidepressant Actions of Ketamine

scientific article published on 10 December 2018

Lack of association between angiotensin I-converting enzyme insertion/deletion gene functional polymorphism and panic disorder in humans.

scientific article published in June 2004

Lack of correlation between phonetic magnetic mismatch field and plasma d-serine levels in humans

scientific article published on 24 April 2018

Lack of deuterium isotope effects in the antidepressant effects of (R)-ketamine in a chronic social defeat stress model

scientific article published on 13 September 2018

Lack of dopamine D1 receptors in the antidepressant actions of (R)-ketamine in a chronic social defeat stress model

scientific article published on 29 March 2019

Lack of metabolism in (R)-ketamine's antidepressant actions in a chronic social defeat stress model

scientific article published on 5 March 2018

Lack of rapid antidepressant effects of Kir4.1 channel inhibitors in a chronic social defeat stress model: Comparison with (R)-ketamine

scientific article published on 28 November 2018

Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine

scientific article published on 07 September 2020

Letter to the Editor: R-ketamine: a rapid-onset and sustained antidepressant without risk of brain toxicity.

scientific article published on 10 June 2016

Long-lasting antidepressant action of ketamine, but not glycogen synthase kinase-3 inhibitor SB216763, in the chronic mild stress model of mice

scientific article

Long-lasting beneficial effects of maternal intake of sulforaphane glucosinolate on gut microbiota in adult offspring

scientific article published in 2022

Longitudinal changes in serum brain-derived neurotrophic factor in accident survivors with posttraumatic stress disorder.

scientific article published on 15 June 2013

Loss of parvalbumin-immunoreactivity in mouse brain regions after repeated intermittent administration of esketamine, but not R-ketamine.

scientific article published on 24 March 2016

Low openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression.

scientific article

MPTP-induced dopaminergic neurotoxicity in mouse brain is attenuated after subsequent intranasal administration of (R)-ketamine: a role of TrkB signaling

scientific article published on 15 August 2019

Maintenance electroconvulsive therapy (ECT) for treatment-resistant disorganized schizophrenia.

scientific article

Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.

scientific article published on 13 November 2014

Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase

scientific article published on 12 May 2020

Mechanistic Target of Rapamycin-Independent Antidepressant Effects of (R)-Ketamine in a Social Defeat Stress Model.

scientific article

Metabolic/inflammatory/vascular comorbidity in psychiatric disorders; soluble epoxide hydrolase (sEH) as a possible new target.

scientific article

Metabolomics of Major Depressive Disorder and Bipolar Disorder: Overview and Future Perspective

scientific article published on 01 February 2018

Microglial activation in schizophrenia and minocycline treatment.

scientific article published on 2 July 2008

Minocycline and St. John's wort as therapeutic drugs for human tauopathy.

scientific article published on 6 May 2015

Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine.

scientific article

Minocycline attenuates subjective rewarding effects of dextroamphetamine in humans.

scientific article

Minocycline produced antidepressant-like effects on the learned helplessness rats with alterations in levels of monoamine in the amygdala and no changes in BDNF levels in the hippocampus at baseline.

scientific article

Modulation of D-serine levels in brains of mice lacking PICK1

scientific article published on 11 January 2008

Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites

scientific article published on 07 November 2019

Mood, psychomotor, and cognitive function in major depressive disorder: from biomarkers to rapid-acting antidepressants

scientific article published on 01 October 2019

Muscle Atrophy and Motor Neuron Degeneration in Human NEDL1 Transgenic Mice ⬇️

scientific article published on October 3, 2010

NMDA- and beta-amyloid1-42-induced neurotoxicity is attenuated in serine racemase knock-out mice.

scientific article

Negative correlation between brain glutathione level and negative symptoms in schizophrenia: a 3T 1H-MRS study

scientific article

Neonatal disruption of serine racemase causes schizophrenia-like behavioral abnormalities in adulthood: clinical rescue by d-serine

scientific article

Neonatal signs following exposure to SSRIs.

scientific article published in October 2005

Neurite outgrowth mediated by the heat shock protein Hsp90α: a novel target for the antipsychotic drug aripiprazole ⬇️

scientific article published on October 16, 2012

Neurite outgrowth mediated by translation elongation factor eEF1A1: a target for antiplatelet agent cilostazol

scientific article

Neuronal brain injury after cerebral ischemic stroke is ameliorated after subsequent administration of (R)-ketamine, but not (S)-ketamine

scientific article published on 07 March 2020

Neuropeptide S attenuates neuropathological, neurochemical and behavioral changes induced by the NMDA receptor antagonist MK-801.

scientific article

Neuropharmacological profile of a novel potential atypical antipsychotic drug Y-931 (8-fluoro-12-(4-methylpiperazin-1-yl)- 6H-[1]benzothieno[2,3-b][1,5] benzodiazepine maleate).

scientific article

Neuropsychiatric Phenotypes Produced by GABA Reduction in Mouse Cortex and Hippocampus

scientific article published on 6 December 2017

Neuropsychological Impairment and Its Association with Violence Risk in Japanese Forensic Psychiatric Patients: A Case-Control Study

scientific article published on 29 January 2016

No Sex-Specific Differences in the Acute Antidepressant Actions of (R)-Ketamine in an Inflammation Model

scientific article published on 01 October 2018

No association of the brain-derived neurotrophic factor (BDNF) gene polymorphisms with panic disorder

scientific article published on 01 June 2005

No changes in serum epidermal growth factor levels in patients with schizophrenia.

scientific article published in June 2005

Occupancy of α7 Nicotinic Acetylcholine Receptors in the Brain by Tropisetron: A Positron Emission Tomography Study Using [(11)C]CHIBA-1001 in Healthy Human Subjects

scientific article published on 31 December 2011

Old drug ifenprodil, new hope for PTSD with a history of childhood abuse.

scientific article

Old drug tipepidine as new hope for children with ADHD

scientific article (publication date: February 2015)

Omega-3 Fatty Acids for Secondary Prevention of Posttraumatic Stress Disorder After Accidental Injury

scientific article published on 01 April 2010

Omega-3 fatty acid supplementation for expectant mothers with depressive symptoms in Japan and Taiwan: An open-label trial.

scientific article published on 23 March 2016

On the Eve of Upgrading Antidepressants: (R)-Ketamine and Its Metabolites.

scientific article published on 14 November 2016

Opposite roles for neuropeptide S in the nucleus accumbens and bed nucleus of the stria terminalis in learned helplessness rats

scientific article published on 16 May 2015

Orally active glutamate carboxypeptidase II inhibitor 2-MPPA attenuates dizocilpine-induced prepulse inhibition deficits in mice.

scientific article published on 18 November 2010

Orbitofrontal cortex abnormality and deficit schizophrenia ⬇️

scientific article published on December 8, 2012

Paclitaxel-induced peripheral neuropathy in patients receiving adjuvant chemotherapy for breast cancer

scientific article

Peripheral IL-6 signaling: a promising therapeutic target for depression?

scientific article published on 4 June 2015

Peripheral interleukin-6 promotes resilience versus susceptibility to inescapable electric stress.

scientific article

Personality traits as risk factors for treatment-resistant depression

scientific article

Pharmacological Characterization of [3H]CHIBA-3007 Binding to Glycine Transporter 1 in the Rat Brain ⬇️

scientific article published on June 23, 2011

Pharmacological characterization of [125I]CHIBA-1006 binding, a new radioligand for α7 nicotinic acetylcholine receptors, to rat brain membranes ⬇️

scientific article published on November 11, 2010

Phase I and pharmacokinetic study of nab-paclitaxel, nanoparticle albumin-bound paclitaxel, administered weekly to Japanese patients with solid tumors and metastatic breast cancer

scientific article published on 19 August 2011

Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent repeated intermittent administration of (R)-ketamine, but not (S)-ketamine: Role of BDNF-TrkB signaling

scientific article published on 19 December 2019

Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent subchronic administration of donepezil: role of sigma-1 receptors.

scientific article published on 9 May 2009

Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of fluvoxamine: role of sigma-1 receptors.

scientific article published on 22 February 2006

Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the glycine transporter-1 inhibitor NFPS and D-serine.

scientific article published on 4 September 2007

Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of tropisetron: role of alpha7 nicotinic receptors.

scientific article published on 10 October 2006

Plasma estradiol levels and antidepressant effects of omega-3 fatty acids in pregnant women

scientific article published on 15 February 2019

Plasma levels of matrix metalloproteinase-9 (MMP-9) are associated with cognitive performance in patients with schizophrenia

scientific article published on 05 February 2020

Possible involvement of brain-derived neurotrophic factor in eating disorders.

scientific article published on 04 April 2012

Possible role of D-serine in the pathophysiology of Alzheimer's disease.

scientific article published in March 2004

Possible role of the gut microbiota-brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model.

scientific article published on 18 December 2017

Post-traumatic Stress Disorder Symptoms in a Female Patient Following Repeated Teasing: Treatment with Gabapentin and Lamotrigine and the Possible Role of Sensitization.

scientific article

Postischemic Brain Injury Is Affected Stereospecifically by Pentazocine in Rats ⬇️

scientific article published on August 1, 1997

Potential role of the sigma-1 receptor chaperone in the beneficial effects of donepezil in dementia with lewy bodies

scientific article published on 24 April 2013

Potentiation of NGF-induced neurite outgrowth in PC12 cells by papaverine: role played by PLC-γ, IP3 receptors.

scientific article published on 4 January 2011

Potentiation of Nerve Growth Factor-Induced Neurite Outgrowth in PC12 Cells by Ifenprodil: The Role of Sigma-1 and IP3 Receptors ⬇️

scientific article (publication date: 2012)

Potentiation of nerve growth factor-induced neurite outgrowth by the ROCK inhibitor Y-27632: a possible role of IP₃ receptors.

scientific article published on 18 September 2010

Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by donepezil: role of sigma-1 receptors and IP3 receptors.

scientific article published on 2 July 2008

Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors.

scientific article

Potentiation of the NMDA receptor-mediated responses through the activation of the glycine site by microglia secreting soluble factors.

scientific article published in April 2006

Preclinical and the first clinical studies on [11C]CHIBA-1001 for mapping alpha7 nicotinic receptors by positron emission tomography.

scientific article published in April 2009

Preliminary genome-wide association study of bipolar disorder in the Japanese population.

scientific article published in December 2009

Prenatal immune activation and subsequent peripubertal stress as a new model of schizophrenia.

scientific article published on July 2013

Prevalence of PTSD and depression among junior middle school students in a rural town far from the epicenter of the Wenchuan earthquake in China

scientific article (publication date: 2012)

Prophylactic effects of sulforaphane on depression-like behavior and dendritic changes in mice after inflammation.

scientific article published on 11 October 2016

Protective effect of LY379268, a selective group II metabotropic glutamate receptor agonist, on dizocilpine-induced neuropathological changes in rat retrosplenial cortex ⬇️

scientific article published on November 28, 2003

Protective effect of the antipsychotic drug zotepine on dizocilpine-induced neuropathological changes in rat retrosplenial cortex.

scientific article published in February 2003

Protective effects of minocycline on 3,4-methylenedioxymethamphetamine-induced neurotoxicity in serotonergic and dopaminergic neurons of mouse brain.

scientific article published on 3 June 2006

Protective effects of minocycline on behavioral changes and neurotoxicity in mice after administration of methamphetamine.

scientific article published on 12 July 2006

Protective effects of minocycline on the reduction of dopamine transporters in the striatum after administration of methamphetamine: a positron emission tomography study in conscious monkeys.

scientific article

Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine.

scientific article

R (-)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine

scientific article

R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects

scientific article

Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with Ketamine

scientific article

Rapid-acting and long-lasting antidepressant-like action of (R)-ketamine in Nrf2 knock-out mice: a role of TrkB signaling

scientific article published on 12 November 2020

Rapid-acting antidepressant ketamine, its metabolites and other candidates: A historical overview and future perspective

scientific article published on 11 July 2019

Recent Advances in the Early Intervention in Schizophrenia: Future Direction from Preclinical Findings

scientific article published on 05 July 2019

Recent Topics on Pharmacotherapy for Amphetamine-Type Stimulants Abuse and Dependence ⬇️

scientific article published on December 1, 2010

Recent development of radioligands for imaging α7 nicotinic acetylcholine receptors in the brain.

scientific article published on January 2010

Reduced Mismatch Negativity is Associated with Increased Plasma Level of Glutamate in First-episode Psychosis

scientific article

Reduced serum levels of brain-derived neurotrophic factor in adult male patients with autism.

scientific article published on 28 July 2006

Reduced serum paraoxonase 1 (PON1) activity in patients with schizophrenia treated with olanzapine but not quetiapine

scientific article published on 11 October 2013

Reduction of Severity of Recurrent Psychotic Episode by Sustained Treatment with Aripiprazole in a Schizophrenic Patient with Dopamine Supersensitivity: A Case Report

scientific article published on February 2017

Reduction of [3H]6-nitroquipazine-labelled 5-hydroxytryptamine uptake sites in rat brain by 3,4-methylenedioxymethamphetamine ⬇️

scientific article published on 01 January 1990

Reduction of dopamine D2/3 receptor binding in the striatum after a single administration of esketamine, but not R-ketamine: a PET study in conscious monkeys

scientific article published on 18 April 2016

Reduction of in vivo binding of [3H]paroxetine in mouse brain by 3,4-methylenedioxymethamphetamine ⬇️

scientific article published on July 1, 1990

Regarding "N-acetyl cysteine as a glutathione precursor for schizophrenia--a double-blind, randomized, placebo-controlled trial".

scientific article

Regional differences in brain-derived neurotrophic factor levels and dendritic spine density confer resilience to inescapable stress

scientific article

Regional differences in dendritic spine density confer resilience to chronic social defeat stress

scientific article

Regional differences in the expression of brain-derived neurotrophic factor (BDNF) pro-peptide, proBDNF and preproBDNF in the brain confer stress resilience.

scientific article published on 19 April 2016

Regulation of brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain by serotonin

scientific article published on 22 February 2016

Regulation of glutamate transporter 1 via BDNF-TrkB signaling plays a role in the anti-apoptotic and antidepressant effects of ketamine in chronic unpredictable stress model of depression.

scientific article

Reliability and validity of the CogState battery Chinese language version in schizophrenia.

scientific article

Reply to: Acute stress symptoms do not worsen in posttraumatic stress disorder and abuse with a single subanesthetic dose of ketamine.

scientific article published on 13 December 2012

Risk of neuropsychiatric disorders in offspring of COVID-19-infected pregnant women and nutritional intervention

scientific article published on 02 June 2020

Risks Associated with Misuse of Ketamine as a Rapid-Acting Antidepressant

scientific article published on 22 November 2016

Role of Actinobacteria and Coriobacteriia in the antidepressant effects of ketamine in an inflammation model of depression

scientific article published on 05 December 2018

Role of Brain-Derived Neurotrophic Factor in Beneficial Effects of Repetitive Transcranial Magnetic Stimulation for Upper Limb Hemiparesis after Stroke.

scientific article

Role of D-serine in the beneficial effects of repetitive transcranial magnetic stimulation in post-stroke patients

scientific article published on 29 January 2020

Role of EphA4 signaling in the pathogenesis of amyotrophic lateral sclerosis and therapeutic potential of traditional Chinese medicine rhynchophylline.

scientific article published on 5 July 2015

Role of Inflammatory Bone Markers in the Antidepressant Actions of (R)-Ketamine in a Chronic Social Defeat Stress Model

scientific article published on 01 November 2018

Role of Keap1-Nrf2 Signaling in Anhedonia Symptoms in a Rat Model of Chronic Neuropathic Pain: Improvement With Sulforaphane

article

Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice

scientific article

Role of NMDA receptor GluN2D subunit in the antidepressant effects of enantiomers of ketamine

scientific article published on 10 November 2017

Role of NMDA receptor subtypes in the induction of catalepsy and increase in Fos protein expression after administration of haloperidol.

scientific article

Role of Serine Racemase in Behavioral Sensitization in Mice after Repeated Administration of Methamphetamine ⬇️

scientific article published on April 18, 2012

Role of Soluble Epoxide Hydrolase in Metabolism of PUFAs in Psychiatric and Neurological Disorders

scientific article published on 30 January 2019

Role of brain-derived neurotrophic factor in eating disorders: recent findings and its pathophysiological implications.

scientific article

Role of hippocampal p11 in the sustained antidepressant effect of ketamine in the chronic unpredictable mild stress model

scientific article published on 23 February 2016

Role of the NMDA receptor in cognitive deficits, anxiety and depressive-like behavior in juvenile and adult mice after neonatal dexamethasone exposure

scientific article published on 17 September 2013

Role of the mTOR signaling pathway in the rapid antidepressant action of ketamine.

scientific article published in January 2011

Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells.

scientific article

Roles of glutamate signaling in preclinical and/or mechanistic models of depression.

scientific article published on 21 April 2011

Rolipram, a selective phosphodiesterase type-IV inhibitor, prevents induction of heat shock protein HSP-70 and hsp-70 mRNA in rat retrosplenial cortex by the NMDA receptor antagonist dizocilpine.

scientific article

Schizophrenia-Like Dopamine Release Abnormalities in a Mouse Model of NMDA Receptor Hypofunction.

scientific article published on 31 January 2018

Serine enantiomers as diagnostic biomarkers for schizophrenia and bipolar disorder.

scientific article published on 12 May 2015

Serum brain-derived neurotrophic factor (BDNF) levels in schizophrenia are indistinguishable from controls.

scientific article published in November 2003

Serum brain-derived neurotrophic factor and antidepressant-naive major depression after lung cancer diagnosis.

scientific article published on 16 September 2011

Serum brain-derived neurotrophic factor as a predictor of incident dementia

scientific article published in May 2014

Serum interleukin-6 is a predictive biomarker for ketamine's antidepressant effect in treatment-resistant patients with major depression.

scientific article published on 9 July 2014

Serum levels of P-selectin in men with high-functioning autism

scientific article published in October 2008

Serum neuropeptide Y in accident survivors with depression or posttraumatic stress disorder

scientific article

Serum oxytocin, posttraumatic coping and C-reactive protein in motor vehicle accident survivors by gender.

scientific article published on 2 June 2015

Shortened protocol in practical [11C]SA4503-PET studies for sigma1 receptor quantification.

scientific article published in February 2008

Sigma receptor ligands: possible application as therapeutic drugs and as radiopharmaceuticals.

scientific article

Sigma-1 Receptor Agonists and Their Clinical Implications in Neuropsychiatric Disorders.

scientific article published in January 2017

Sigma-1 receptor agonist fluvoxamine for delirium in intensive care units: report of five cases.

scientific article

Sigma-1 receptor agonist fluvoxamine for delirium in older adults.

scientific article published on 3 November 2011

Sigma-1 receptor agonist fluvoxamine for postoperative delirium in older adults: report of three cases.

scientific article published on 24 June 2010

Sigma-1 receptor agonists as therapeutic drugs for cognitive impairment in neuropsychiatric diseases.

scientific article published on January 2012

Sigma-1 receptor chaperone and brain-derived neurotrophic factor: emerging links between cardiovascular disease and depression.

scientific article published on 05 October 2012

Sigma-1 receptors and selective serotonin reuptake inhibitors: clinical implications of their relationship

scientific article

Social Isolation-Induced Aggression Potentiates Anxiety and Depressive-Like Behavior in Male Mice Subjected to Unpredictable Chronic Mild Stress ⬇️

scientific article published on June 17, 2011

Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease

scientific article published on 07 May 2018

Soluble epoxide hydrolase: a new therapeutic target for depression.

scientific article published on 18 August 2016

Specific metabolites in the medial prefrontal cortex are associated with the neurocognitive deficits in schizophrenia: a preliminary study.

scientific article published on 19 October 2009

Splenic NKG2D confers resilience versus susceptibility in mice after chronic social defeat stress: beneficial effects of (R)-ketamine

scientific article published on 24 December 2019

Striatal dopamine level increases in the urinary storage phase in cats: an in vivo microdialysis study.

scientific article published in January 2005

Subchronic treatment with methamphetamine and phencyclidine differentially alters the adenosine A1 and A2A receptors in the prefrontal cortex, hippocampus, and striatum of the rat.

scientific article published in April 2001

Supplementation with D-serine prevents the onset of cognitive deficits in adult offspring after maternal immune activation.

scientific article published on 17 November 2016

Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase.

scientific article

Synthesis and biological evaluation of D-amino acid oxidase inhibitors.

scientific article published on 29 May 2008

Targeting of NMDA receptors in new treatments for schizophrenia

scientific article published on 26 June 2014

Targeting of NMDA receptors in the treatment of major depression

scientific article

Targeting of α7 Nicotinic Acetylcholine Receptors in the Treatment of Schizophrenia and the Use of Auditory Sensory Gating as a Translational Biomarker

scientific article published on 05 June 2015

Targeting the sigma-1 receptor chaperone in the treatment of perinatal brain injury

scientific article published on 10 January 2015

The Efficacy of Omega-3 Fatty Acids for Depressive Symptoms among Pregnant Women in Japan and Taiwan: A Randomized, Double-Blind, Placebo-Controlled Trial (SYNCHRO; NCT01948596)

scientific article published on 12 December 2018

The Piccolo Intronic Single Nucleotide Polymorphism rs13438494 Regulates Dopamine and Serotonin Uptake and Shows Associations with Dependence-Like Behavior in Genomic Association Study.

scientific article published in January 2015

The R-Stereoisomer of Ketamine as an Alternative for Ketamine for Treatment-resistant Major Depression.

scientific article published on 24 April 2014

The Tachikawa cohort of motor vehicle accident study investigating psychological distress: design, methods and cohort profiles.

scientific article published on 25 September 2008

The antibiotic minocycline prevents methamphetamine-induced rewarding effects in mice.

scientific article published on 12 January 2012

The cognitive impairments and psychological wellbeing of methamphetamine dependent patients compared with health controls.

scientific article

The effect of the antipsychotic drug mosapramine on the expression of Fos protein in the rat brain: comparison with haloperidol, clozapine and risperidone

scientific article published on 01 October 2000

The effects of FK506, a specific calcineurin inhibitor, on methamphetamine-induced behavioral change and its sensitization in rats.

scientific article published in November 2001

The effects of dentate granule cell destruction on behavioural activity and Fos protein expression induced by systemic methamphetamine in rats

scientific article

The immunophilin ligand FK506 protects against methamphetamine-induced dopaminergic neurotoxicity in mouse striatum.

scientific article

The incidence and management of metachronous testicular germ cell tumors in patients with extragonadal germ cell tumors

scientific article published on 14 May 2010

The synchronized trial on expectant mothers with depressive symptoms by omega-3 PUFAs (SYNCHRO): Study protocol for a randomized controlled trial

scientific article

Therapeutic effects of metabotropic glutamate receptor 5 positive allosteric modulator CDPPB on phencyclidine‐induced cognitive deficits in mice ⬇️

scientific article published on May 17, 2012

Therapeutic implications for NMDA receptors in mood disorders.

scientific article published in July 2013

Treatment concerns for psychiatric symptoms in COVID-19-infected patients with or without psychiatric disorders

scientific article published on 09 April 2020

Tropisetron and its targets in Alzheimer's disease

scientific article published on 15 November 2014

Tropisetron for postoperative cognitive decline

scientific article

Tropisetron improves deficits in auditory P50 suppression in schizophrenia

scientific article

Two clusters of serum midkine levels in drug-naive patients with schizophrenia

scientific article published on 01 June 2003

Understanding depression: linking brain-derived neurotrophic factor, transglutaminase 2 and serotonin ⬇️

scientific article published on January 1, 2013

Understanding the link between maternal infections and neurodevelopmental disorders in offspring: The role of abnormalities in metabolism of polyunsaturated fatty acids

scientific article published on 05 August 2019

Use of squamous cell carcinoma antigen as a biomarker of chemotherapy response in patients with metastatic cervical carcinoma

scientific article published on 10 August 2011

What Are the Causes for Discrepancies of Antidepressant Actions of (2R,6R)-Hydroxynorketamine?

scientific article published on 27 December 2017

YM90K, a selective-amino-3-hydroxy5-methyl-4-isoxazole propionate (AMPA) receptor antagonist, prevents induction of heat shock protein HSP -70 and hsp -70 mRNA in rat retrosplenial cortex by phencyclidine.

scientific article

[11C]CHIBA-1001 as a novel PET ligand for alpha7 nicotinic receptors in the brain: a PET study in conscious monkeys.

scientific article

[Depression and BDNF]

scientific article published on 01 March 2006

[Development of new drugs targeting glial cells]

scientific article published on 01 September 2007

α7 nicotinic acetylcholine receptor as a potential therapeutic target for schizophrenia.

scientific article published on January 2011

Paulina is supported by:

About Paulina

Help