List of works by Maria Castedo

A cellular machine generating apoptosis-prone aneuploid cells.

scientific article published in January 2005

An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells

scientific article published on January 2013

An automated fluorescence videomicroscopy assay for the detection of mitotic catastrophe

scientific article

An immunosurveillance mechanism controls cancer cell ploidy

scientific article

Anti-renin T cells trigger normal B cells to produce anti-renin antibodies and normalize blood pressure in spontaneously hypertensive rats

scientific article published on 01 December 1993

Apaf-1 Deficiency Causes Chromosomal Instability.

scientific article published on 14 September 2007

Apoptosis regulation in tetraploid cancer cells

scientific article

CD69-induced monocyte apoptosis involves multiple nonredundant signaling pathways

scientific article published on 01 September 1996

Calreticulin exposure dictates the immunogenicity of cancer cell death

scientific article

Caspase 2 in mitotic catastrophe: The terminator of aneuploid and tetraploid cells.

scientific article published on 10 March 2017

Caspase independence of radio-induced cell death

scientific article published on 24 July 2006

Cell death modalities: classification and pathophysiological implications

scientific article published on 13 April 2007

Characterization of novel MPS1 inhibitors with preclinical anticancer activity

scientific article

Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells

scientific article

Cisplatin resistance associated with PARP hyperactivation

scientific article

Contagious apoptosis facilitated by the HIV-1 envelope: fusion-induced cell-to-cell transmission of a lethal signal

scientific article published on 19 October 2004

Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe.

scientific article

Cytofluorometric assessment of cell cycle progression

scientific article

Cytofluorometric purification of diploid and tetraploid cancer cells.

scientific article published on January 2011

Effects of acyl-coenzyme A binding protein (ACBP)/diazepam-binding inhibitor (DBI) on body mass index

scientific article published on 09 June 2021

Enhancement of radiation response in p53-deficient cancer cells by the Aurora-B kinase inhibitor AZD1152.

scientific article

Functions of BCL-X L at the Interface between Cell Death and Metabolism

scientific article published on 28 February 2013

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

scientific article published on 17 April 2009

HIV-1 protease inhibitors and cytomegalovirus vMIA induce mitochondrial fragmentation without triggering apoptosis.

scientific article published in February 2006

Illicit survival of cancer cells during polyploidization and depolyploidization

scientific article

Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy.

scientific article published in May 2013

Immunosurveillance against cancer-associated hyperploidy.

scientific article published in November 2012

Immunosurveillance against tetraploidization-induced colon tumorigenesis

scientific article published on 16 January 2013

Implication of mitochondria in apoptosis.

scientific article published on September 1997

Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone

scientific article published in July 2008

Improvement of TH1 functions during the regulation phase of mercury disease in brown Norway rats

scientific article published on 01 February 1994

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

scientific article (publication date: 2007)

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

scientific article published in April 1996

Involvement of p38alpha in the mitotic progression of p53(-/-) tetraploid cells.

scientific article published on 3 July 2010

Metabolic enzymes expressed by cancer cells impact the immune infiltrate

scientific article published on 30 March 2019

Metabolic vulnerability of cisplatin-resistant cancers

scientific article published on 06 June 2018

Mitochondrial control of nuclear apoptosis.

scientific article

Mitochondrial gateways to cancer

scientific article published on 19 August 2009

Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo

scientific article published on 01 December 1995

Mitochondrion-dependent caspase activation by the HIV-1 envelope

scientific article published on 01 October 2003

Mitochondrion-targeted apoptosis regulators of viral origin.

scientific article

Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.

scientific article published on May 2004

Mitotic catastrophe: a mechanism for avoiding genomic instability.

scientific article published on 29 April 2011

Molecular mechanisms of cisplatin resistance

scientific article published on 05 September 2011

Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos.

scientific article

Negative prognostic value of high levels of intracellular poly(ADP-ribose) in non-small cell lung cancer.

scientific article

Nonapoptotic Role for Apaf-1 in the DNA Damage Checkpoint

Nonapoptotic role for Apaf-1 in the DNA damage checkpoint

scientific article published on November 2007

Polyethylene Glycol-Modified IL-2 Abrogates Superantigen-Induced Anergy without Affecting Peripheral Clonal Deletionin Vivo

scientific article published on 01 March 1996

Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint.

scientific article published on 21 October 2004

Predictive biomarkers for cancer therapy with PARP inhibitors.

scientific article published on 16 September 2013

Preferential killing of p53-deficient cancer cells by reversine.

scientific article

Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5.

scientific article published on 27 April 2009

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

article

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.

scientific article published on 16 April 2009

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

scientific article

Selective killing of p53-deficient cancer cells by SP600125.

scientific article

Selective resistance of tetraploid cancer cells against DNA damage-induced apoptosis

scientific article published on December 2006

Self-reactive anti-class II T helper type 2 cell lines derived from gold salt-injected rats trigger B cell polycolonal activation and transfer autoimmunity in CD8-depleted normal syngeneic recipients.

scientific article

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

scientific article published on August 1, 1995

Systems biology of cisplatin resistance: past, present and future

scientific article

Tantalizing Thanatos: unexpected links in death pathways

scientific article published on 01 July 2002

The beauty of death

scientific article published on 01 September 2002

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

scientific article published on 27 March 2009

Transgenerational cell fate profiling: a method for the graphical presentation of complex cell cycle alterations

scientific article

Vitamin B6 metabolism influences the intracellular accumulation of cisplatin

scientific article published on February 2012

Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition

scientific article published on 30 November 2015

p53 represses the polyploidization of primary mammary epithelial cells by activating apoptosis.

scientific article published on 26 May 2009