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List of works by Ole Didrik Lærum

A Norwegian cancer researcher honoured by a memorial

scientific article published in December 2003

A cerebral glioma model for experimental therapy and in vivo invasion studies in syngeneic BD IX rats

scientific article published on October 1990

A synthetic hemoregulatory peptide (HP5B) inhibits human myelopoietic colony formation (CFU-GM) but not leukocyte phagocytosis in vitro

scientific article published on 01 September 1987

Acute systemic toxicity of combined cis-diamminedichloroplatinum and hyperthermia in the rat

scientific article published on 01 April 1987

Adherent-cell-dependent stimulation of CFU-GM by nucleobases, nucleosides, their analogues, and the hemoregulatory peptide dimer

scientific article published on 01 February 1992

Age-related differences and circadian and seasonal variations of myelopoietic progenitor cell (CFU-GM) numbers in mice.

scientific article published in January 1988

Altered expression of the urokinase receptor homologue, C4.4A, in invasive areas of human esophageal squamous cell carcinoma

scientific article

Altered neutrophil functions in patients with large burns

scientific article published on 01 January 1990

Altered polymorphonuclear neutrophilic granulocyte functions in patients with large burns

scientific article published on 01 June 1989

Anti-GM2 monoclonal antibodies induce necrosis in GM2-rich cultures of a human glioma cell line

scientific article published on September 1991

Brain tumour development and invasion. An interview with Ole Didrik Laerum

scientific article published in January 2004

C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

scientific article published on 12 May 2016

Cell and tissue culture of the central nervous system: recent developments and current applications

scientific article

Characterization of NCAM expression and function in BT4C and BT4Cn glioma cells

scientific article published on January 1991

Circadian and circannual variations of cell cycle distribution in the mouse bone marrow

scientific article published on 01 January 1988

Circadian and infradian aspects of the cell cycle: from past to future

scientific article published on October 1989

Circadian cell cycle variations of erythro‐ and myelopoiesis in humans ⬇️

scientific article published on 01 May 1997

Circadian cell kinetics in humans. Aspects related to cancer chemotherapy.

scientific article published on November 1995

Circadian expression of clock genes in purified hematopoietic stem cells is developmentally regulated in mouse bone marrow

scientific article

Circadian oscillators in eukaryotes

scientific article published on September 2010

Circadian phase relationships between peripheral blood variables and bone marrow proliferative activity in clinical health

scientific article published on 01 July 1995

Circadian variations in clock gene expression of human bone marrow CD34+ cells

scientific article published in April 2007

Clock gene expression in purified mouse hematopoietic stem cells

scientific article published in January 2005

Colony-forming unit-granulocyte-macrophage and DNA synthesis of human bone marrow are circadian stage-dependent and show covariation

scientific article published on 01 May 1992

Comparison of a linear miniature ultrasound probe and a radial-scanning echoendoscope in TN staging of esophageal cancer

scientific article published on 01 September 2000

Crohn's disease but not chronic ulcerative colitis induces the expression of PAI-1 in enteric neurons

scientific article published on 01 September 2008

Cryobiology-- freeze preservation and storage of living cells and tissues

scientific article published on October 2004

Current concepts for chronochemotherapy of cancer

scientific article published on January 1995

Cytokinetic circadian patterns in human host and tumor

scientific article published on 01 January 1995

Cytometry and Time-Dependent Variations in Peripheral Blood and Bone Marrow Cells: A Literature Review and Relevance to the Chronotherapy of Cancer ⬇️

scientific article published on January 1, 1991

DNA content and chromosomal composition of malignant human gliomas.

scientific article

DNA content and chromosomes in permanent cultured cell lines derived from malignant human gliomas.

scientific article published in October 1987

DNA synthesis and ploidy in non-Hodgkin's lymphomas demonstrate intrapatient variation depending on circadian stage of cell sampling

scientific article published on 01 July 1993

DNA synthesis in human bone marrow is circadian stage dependent

scientific article published on 01 June 1991

Deletion-mutant epidermal growth factor receptor in human gliomas: Effect of type II mutation on receptor function ⬇️

scientific article published on August 15, 1991

Deoxycytidine, insulin and epidermal growth factor overcome the effect of two natural inhibitors of the haemopoietic system

scientific article published on 01 January 1988

Differential effects of 12-O-tetradecanoyl-13-phorbol acetate (TPA) on growth, migration and invasion of a human glioma cell line.

scientific article published on September 1993

Differential effects of vincristine and phenytoin on the proliferation, migration, and invasion of human glioma cell lines.

scientific article published in June 1995

Differentiation markers (S-100, GFAP, NSE and D2) in fetal rat brain cells during malignant transformation in cell culture

scientific article

Dynamic determination of human glioma invasion in vitro

scientific article

Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro.

scientific article published on September 1990

Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro

scientific article published in January 1993

Effects of a hemoregulatory peptide (HP5b) on erythroid and myelopoietic colony formation in vitro

scientific article published on 01 August 1986

Effects of growth factors on a human glioma cell line during invasion into rat brain aggregates in culture

scientific article published on January 1992

Effects of high and low single dose irradiation on glioma spheroid invasion into normal rat brain tissue in vitro

scientific article published on September 1, 1992

Enzyme activities in biopsy specimens from large-bowel mucosa in colorectal adenomas and carcinomas

scientific article published on 01 June 1987

Enzyme activities in biopsy specimens from large-bowel mucosa in ulcerative colitis

scientific article published on 01 May 1987

Enzyme activities in human gastric cancer and polyps

scientific article published on 01 December 1986

Enzyme activities in human gastric mucosa in gastritis and resected stomachs

scientific article published on 01 December 1986

Expression of C4.4A in precursor lesions of pulmonary adenocarcinoma and squamous cell carcinoma

scientific article

Expression of annexin II in glioma cell lines and in brain tumor biopsies

scientific article published in May 1998

Expression of circadian clock genes and proteins in urothelial cancer is related to cancer-associated genes

scientific article

Expression of the Ly6/uPAR-domain proteins C4.4A and Haldisin in non-invasive and invasive skin lesions

scientific article

Flow cytometric DNA studies in human gastric cancer and polyps

scientific article

Flow cytometric DNA studies in normal human gastric mucosa, gastritis, and resected stomachs

scientific article published on 01 August 1987

Flow cytometric assay for the measurement of human bone marrow phenotype, function and cell cycle

scientific article published on 01 January 1990

Flow cytometric assessment of peripheral blood contamination and proliferative activity of human bone marrow cell populations

scientific article

Flow cytometric measurement of DNA S-phase in human bone marrow cells: correcting for peripheral blood contamination.

scientific article published in March 1996

Flow cytometric measurement of p53 protein expression and DNA content in paraffin-embedded tissue from bronchial carcinomas

scientific article published on January 1991

Flow cytometry for the study of phagocyte functions

scientific article published on January 1989

Flow cytometry of biopsy specimens from ulcerative colitis, colorectal adenomas, and carcinomas

scientific article published on 01 December 1987

Glioma cell interactions with fetal rat brain aggregates in vitro and with brain tissue in vivo

scientific article published in August 1986

Glutathione content in human bone marrow and circadian stage relation to DNA synthesis

scientific article published on 01 August 1991

Growth arrest and polyploidization induced by metahalone microtubule inhibitors on rat glioma cells in culture

scientific article published on January 1986

Growth pattern of colorectal liver metastasis as a marker of recurrence risk

scientific article published on 31 March 2015

HPV subtypes in cervical cancer biopsies between 1930 and 2004: detection using general primer pair PCR and sequencing

scientific article published on 10 June 2006

Helicobacter pylori Colonization Drives Urokinase Receptor (uPAR) Expression in Murine Gastric Epithelium During Early Pathogenesis

scientific article published on 09 July 2020

Hemoregulatory peptide (HP5b) dimer effects on normal and malignant cells in culture

scientific article published on July 1993

Heterogeneous effects of bradykinin and a23187 on glioma growth, migration and invasion.

scientific article published in July 1994

Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-alpha, bFGF, IL-2] on glioma spheroid growth, migration and invasion

scientific article

High-frequency ultrasonographic imaging of the gastrointestinal wall ⬇️

scientific article published on May 1, 2012

Histopathological growth pattern, proteolysis and angiogenesis in chemonaive patients resected for multiple colorectal liver metastases

scientific article published on 2 August 2012

Identification of a regulatory peptide distinct from normal granulocyte-derived hemoregulatory peptide produced by human promyelocytic HL-60 leukemia cells after differentiation induction with retinoic acid

scientific article published on 01 September 1986

Immunocytochemical characterization of extracellular matrix proteins expressed by cultured glioma cells.

scientific article published in October 1989

Immunohistochemical markers in urinary bladder carcinomas from paraffin-embedded archival tissue after storage for 5-70 years

scientific article published on May 2007

Induction of circadian rhythm in cultured human mesenchymal stem cells by serum shock and cAMP analogs in vitro

scientific article published in February 2009

Inflammation and uPAR-Expression in Colorectal Liver Metastases in Relation to Growth Pattern and Neo-adjuvant Therapy.

scientific article published on 14 August 2015

Influence of remote cancer and obesity on, and distribution of mucosal enzymes in, the upper small intestine

scientific article published in October 1986

Inhibition of phagocytosis by monoclonal antibodies to human myeloid differentiation antigens

scientific article published on 01 December 1984

Inhibitory effects of a synthetic pentapeptide on hemopoietic stem cells in vitro and in vivo

scientific article published on 01 January 1984

Interaction between human brain tumour biopsies and fetal rat brain tissue in vitro.

scientific article published in January 1990

Interaction between human medulloblastomas and foetal rat brain aggregates in vitro

scientific article published on January 1994

Interaction between rat glioma cells and normal rat brain tissue in organ culture

scientific article published in May 1985

Interactions between fetal rat brain cells and mature brain tissue in vivo and in vitro

scientific article

International consensus guidelines for scoring the histopathological growth patterns of liver metastasis

scientific article

Invasive glioma cells in tissue culture

scientific article published on September 1990

Invasiveness by lacZ transfected non-small cell lung cancer cells into human bronchial tissues in vitro ⬇️

scientific article published on July 1, 1998

Invasiveness in vitro and biological markers in human primary glioblastomas

scientific article published on August 1, 2001

Invasiveness of human glioma cell lines in vitro: relation to tumorigenicity in athymic mice

scientific article published in January 1987

Invasiveness of primary brain tumors

scientific article published on January 1984

Leptomeningeal tissue: a barrier against brain tumor cell invasion

scientific article published on 01 November 1994

Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells.

scientific article published on 13 September 2010

Local spread of malignant neuroepithelial tumors ⬇️

scientific article published on January 1, 1997

Long-term survival from adenocarcinoma of the esophagus after transthoracic and transhiatal esophagectomy ⬇️

scientific article published on June 30, 2012

Ly6/uPAR-related protein C4.4A as a marker of solid growth pattern and poor prognosis in lung adenocarcinoma

scientific article published on 01 February 2013

MMP-9 is differentially expressed in primary human colorectal adenocarcinomas and their metastases

scientific article published on 01 May 2006

Magnus Haaland--a pioneer in international cancer research

scientific article published on March 2001

Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model

scientific article published on September 2008

Microvessel density and endothelial cell proliferation levels in colorectal liver metastases from patients given neo-adjuvant cytotoxic chemotherapy and bevacizumab

scientific article published on 28 October 2015

Modulation of murine hemopoiesis in vivo by a synthetic hemoregulatory pentapeptide (HP 5b)

scientific article published on 01 January 1984

Molecular analysis of the PI3K-AKT pathway in uterine cervical neoplasia: frequent PIK3CA amplification and AKT phosphorylation

scientific article published in April 2006

Multicellular tumor spheroids from human gliomas maintained in organ culture

scientific article published in March 1990

Multipotent stem cell (CFU-S) numbers and circadian variations in aging mice

scientific article published on 01 September 1988

Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori

scientific article published in September 2009

No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer

scientific article

Non-small-cell lung carcinoma cells invade human bronchial mucosa In vitro ⬇️

scientific article published on April 1, 1998

Nonadhesive stationary organ culture of human bronchial mucosa

scientific article published on 01 August 1996

Peripheral blood leukocyte alterations in mice induced by a hemoregulatory pentapeptide (HP 5b)

scientific article published on 01 January 1985

Phagocytic capacity of normal and malignant rat glial cells in culture.

scientific article published in February 1987

Phenotypic properties of neoplastic cell lines developed from fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo ⬇️

scientific article published on August 15, 1977

Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner.

scientific article

Prevention of hematotoxic side effects of cytostatic drugs in mice by a synthetic hemoregulatory peptide

scientific article published on 01 January 1990

Prognosis in adenocarcinomas of lower oesophagus, gastro-oesophageal junction and cardia evaluated by uPAR-immunohistochemistry

scientific article published on 20 October 2011

Prognostic significance of p53 protein expression and DNA ploidy in surgically treated non-small cell lung carcinomas

scientific article published on May 1993

Prolonged Duodenal Mucosal Lymphocyte Alterations in Patients With and Without Postinfectious Functional Gastrointestinal Disorders After Giardia Infection.

scientific article

Protein disulfide isomerase expression is related to the invasive properties of malignant glioma

scientific article published on October 2006

Quantitation of biological tumor markers (p53, c-myc, Ki-67 and DNA ploidy) by multiparameter flow cytometry in non-small-cell lung cancer

scientific article published on December 2, 1992

Reaggregation of fetal rat brain cells in a stationary culture system. I: Methodology and cell identification

scientific article published in April 1986

Rhythmic variations of different hemopoietic cell lines and maturation stages in aging mice

scientific article published on 01 January 1988

Rhythms in human bone marrow and blood cells

scientific article

Rhythms in the bone marrow and blood: differences as to day and night

scientific article published on 01 May 1989

Selectivity of hemoregulatory peptide (HP5b) action in culture

scientific article published on November 1990

Simultaneous measurement of phagocytosis and phagosomal pH by flow cytometry: role of polymorphonuclear neutrophilic leukocyte granules in phagosome acidification

scientific article published on 01 November 1983

Smoking prevention. Courses on smoking prevention conducted at a regional hospital

scientific article published on 01 April 1989

Spontaneous lung and lymph node metastasis in transgenic breast cancer is independent of the urokinase receptor uPAR.

scientific article published on 4 June 2015

Spontaneous metastasis in congenic mice with transgenic breast cancer is unaffected by plasminogen gene ablation

scientific article

Subepithelial masses of the gastrointestinal tract evaluated by endoscopic ultrasonography

scientific article published on 01 June 2002

Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180

The dimer of hemoregulatory peptide (HP5B) stimulates mouse and human myelopoiesis in vitro.

scientific article published in May 1988

The sequence of the hemoregulatory peptide is present in Gi alpha proteins

scientific article published in August 1990

Theoretical and practical aspects of circadian coordination of host and tumor

scientific article published on January 1, 1995

Three-dimensional growth of glial cell lines affects growth factor and growth factor receptor mRNA levels.

scientific article published in September 1994

Time-dependent biological differences in molecular markers of high-grade urothelial cancer over 7 decades (ras proteins, pTEN, uPAR, PAI-1 and MMP-9)

scientific article published on 06 October 2012

Tissue Inhibitor of Metalloproteinase-1 Is Confined to Tumor-Associated Myofibroblasts and Is Increased With Progression in Gastric Adenocarcinoma

scientific article published on July 2016

Tissue inhibitor of matrix metalloproteinase-1 expression in colorectal cancer liver metastases is associated with vascular structures.

scientific article

Transfection of glioma cells with the neural-cell adhesion molecule NCAM: effect on glioma-cell invasion and growth in vivo

scientific article published on July 1994

Transmission electron microscopy of cocultures between normal rat brain tissue and rat glioma cells

scientific article

Tumour fragment spheroids from human non-small-cell lung cancer maintained in organ culture

scientific article published on 01 January 1995

Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases

scientific article published on 01 April 2009

Ultrasonic diagnosis in parenchymal liver disease

scientific article published in May 1986

Urokinase plasminogen activator receptor is expressed in invasive cells in gastric carcinomas from high- and low-risk countries

scientific article published in January 2010

Urokinase plasminogen activator receptor on invasive cancer cells: a prognostic factor in distal gastric adenocarcinoma

scientific article published on 20 October 2011

Urokinase-type plasminogen activator receptor (uPAR) expression is associated with T-stage and survival in urothelial carcinoma of the bladder

scientific article

Urokinase-type plasminogen activator receptor (uPAR) on tumor-associated macrophages is a marker of poor prognosis in colorectal cancer

scientific article

Variation in cell yield and proliferative activity of positive selected human CD34+ bone marrow cells along the circadian time scale ⬇️

scientific article published on 01 January 1998

Whipple's disease. Demonstration of a persisting monocyte and macrophage dysfunction

scientific article published on 01 June 1988

Zebrafish kidney marrow contains ABCG2-dependent side population cells exhibiting hematopoietic stem cell properties

scientific article published on 11 December 2006

[Pathology archives--new perspectives on stored tissue material].

scientific article published in January 2003

[Sources of information about medical equipment and instruments from earlier times].

scientific article

[Whipple's disease]

scientific article published on 01 August 1985

uPAR Expression Pattern in Patients with Urothelial Carcinoma of the Bladder--Possible Clinical Implications

scientific article published on 20 August 2015

«I'm a Norwegian doctor»--a quotation with a life of its own.

scientific article published in December 2013

αB-Crystallin Is Elevated in Highly Infiltrative Apoptosis-Resistant Glioblastoma Cells ⬇️

scientific article published on September 2, 2010

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