Search filters

List of works by S H Ghaffari

ASXL1 and JAK2V617F gene mutation screening in Iranian patients with chronic myeloid leukemia.

scientific article published on 19 September 2016

AZD1152-HQPA induces growth arrest and apoptosis in androgen-dependent prostate cancer cell line (LNCaP) via producing aneugenic micronuclei and polyploidy.

scientific article published on 3 October 2014

Acquired expression of osteopontin selectively promotes enrichment of leukemia stem cells through AKT/mTOR/PTEN/β-catenin pathways in AML cells.

scientific article published on 07 April 2016

Aging of mesenchymal stem cell in vitro.

scientific article

Alteration in miRNA gene expression pattern in acute promyelocytic leukemia cell induced by arsenic trioxide: a possible mechanism to explain arsenic multi-target action.

scientific article

An overview of microRNAs: Biology, functions, therapeutics, and analysis methods

scientific article published on 23 November 2018

Anti-tumor activity of PI3K-δ inhibitor in hematologic malignant cells: Shedding new light on resistance to Idelalisib.

scientific article published on 22 February 2017

Anti-tumour activity of tivozanib, a pan-inhibitor of VEGF receptors, in therapy-resistant ovarian carcinoma cells

scientific article published on 06 April 2017

Antileukemic effects of neurokinin-1 receptor inhibition on hematologic malignant cells: a novel therapeutic potential for aprepitant.

scientific article published on 31 January 2018

Apigenin modulates the expression levels of pro-inflammatory mediators to reduce the human insulin amyloid-induced oxidant damages in SK-N-MC cells.

scientific article published on 10 October 2014

Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-κB-mediated induction of XIAP

scientific article published on 10 September 2009

Arsenic trioxide induces cell cycle arrest and alters DNA methylation patterns of cell cycle regulatory genes in colorectal cancer cells

scientific article published on 18 October 2016

Autocrine human growth hormone expression leads to resistance of MCF-7 cells to tamoxifen.

scientific article

Autocrine human growth hormone increases sensitivity of mammary carcinoma cell to arsenic trioxide-induced apoptosis.

scientific article published on 10 July 2013

BIBR 1532 increases arsenic trioxide-mediated apoptosis in acute promyelocytic leukemia cells: therapeutic potential for APL.

scientific article

Blockade of JAK2/STAT3 intensifies the anti-tumor activity of arsenic trioxide in acute myeloid leukemia cells: Novel synergistic mechanism via the mediation of reactive oxygen species

scientific article published on 19 July 2018

Blockade of vascular endothelial growth factor receptors by tivozanib has potential anti-tumour effects on human glioblastoma cells

scientific article published on 13 March 2017

Characterization of arsenic-induced cytogenetic alterations in acute promyelocytic leukemia cell line, NB4.

scientific article published on 5 May 2011

Communication of substance P, calcitonin-gene-related neuropeptides and chemokine receptor 4 (CXCR4) in cord blood hematopoietic stem cells

article

Concomitant presence of JAK2 V617F mutation and BCR-ABL translocation in a pregnant woman with polycythemia vera.

scientific article published on 25 May 2010

Contributory role of microRNAs in anti-cancer effects of small molecule inhibitor of telomerase (BIBR1532) on acute promyelocytic leukemia cell line

scientific article published on 15 January 2019

Dacomitinib, a pan-inhibitor of ErbB receptors, suppresses growth and invasive capacity of chemoresistant ovarian carcinoma cells

scientific article

Delivery of disulfiram into breast cancer cells using folate-receptor-targeted PLGA-PEG nanoparticles: in vitro and in vivo investigations

scientific article published on 21 April 2016

Demethylation and alterations in the expression level of the cell cycle-related genes as possible mechanisms in arsenic trioxide-induced cell cycle arrest in human breast cancer cells.

scientific article published on February 2017

Differential sensitivity of p44/p42-MAPK- and PI3K/Akt-targeted neuroblastoma subtypes to arsenic trioxide

scientific article published on 23 October 2013

Direct short-term cytotoxic effects of BIBR 1532 on acute promyelocytic leukemia cells through induction of p21 coupled with downregulation of c-Myc and hTERT transcription.

scientific article published on January 2012

Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway

scientific article published on 19 October 2015

Erratum to: Expression pattern of hTERT telomerase subunit gene in different stages of chronic myeloid leukemia.

scientific article published on 29 February 2016

Evaluation of antitumor activity of a TGF-beta receptor I inhibitor (SD-208) on human colon adenocarcinoma.

scientific article

Expression Analysis of PVT1, CCDC26, and CCAT1 Long Noncoding RNAs in Acute Myeloid Leukemia Patients

scientific article published on 14 September 2018

Expression analysis of microRNA-125 in patients with polycythemia vera and essential thrombocythemia and correlation with JAK2 allele burden and laboratory findings

scientific article

Expression pattern of hTERT telomerase subunit gene in different stages of chronic myeloid leukemia.

scientific article

Fludarabine and busulfan as a myeloablative conditioning regimen for allogeneic stem cell transplantation in high- and standard-risk leukemic patients

scientific article published on 30 April 2007

Hepatocytes of donor origin in recipient liver after hematopoietic SCT in beta-thalassemia major patients.

scientific article published on 7 September 2009

IL-6/IL-6R pathway is a therapeutic target in chemoresistant ovarian cancer

scientific article published on 19 July 2018

Identification of novel p53 target genes by cDNA AFLP in glioblastoma cells.

scientific article published on 24 September 2008

Immunoglobulin heavy chain constant and heavy chain variable region genes in phylogenetically diverse species of bony fish

scientific article published on 01 May 1993

Inhibition of tachykinin NK1 receptor using aprepitant induces apoptotic cell death and G1 arrest through Akt/p53 axis in pre-B acute lymphoblastic leukemia cells

scientific article published on 05 September 2016

Inhibition of telomerase using BIBR1532 enhances doxorubicin-induced apoptosis in pre-B acute lymphoblastic leukemia cells.

scientific article published on 5 January 2017

Inhibitor of Aurora Kinase B Induces Differentially Cell Death and Polyploidy via DNA Damage Response Pathways in Neurological Malignancy: Shedding New Light on the Challenge of Resistance to AZD1152-HQPA.

scientific article

Inhibitor of pan class-I PI3K induces differentially apoptotic pathways in acute leukemia cells: Shedding new light on NVP-BKM120 mechanism of action.

scientific article

Isolation of proteins for peptide mapping, amino acid analyses, and sequencing using disulfide crosslinked polyacrylamide gels ⬇️

scientific article published on June 1, 1988

Lithium attenuated the depressant and anxiogenic effect of juvenile social stress through mitigating the negative impact of interlukin-1β and nitric oxide on hypothalamic-pituitary-adrenal axis function

scientific article published on 18 December 2015

Low Expression of Long Noncoding RNA IRAIN Is Associated with Poor Prognosis in Non-M3 Acute Myeloid Leukemia Patients.

scientific article published on 10 April 2018

Melatonin promotes ATO-induced apoptosis in MCF-7 cells: Proposing novel therapeutic potential for breast cancer.

scientific article published on 15 July 2016

Metabolism of arsenic trioxide in acute promyelocytic leukemia cells.

scientific article published on October 2014

Minimal residual disease (MRD) detection using rearrangement of immunoglobulin/T cell receptor genes in adult patients with acute lymphoblastic leukemia (ALL).

scientific article published in February 2018

Monitoring of cytomegalovirus reactivation in bone marrow transplant recipients by real-time PCR.

scientific article

Multifaceted suppression of aggressive behavior of thyroid carcinoma by all-trans retinoic acid induced re-differentiation

scientific article published on September 6, 2011

Multitargeting and antimetastatic potentials of silibinin in human HepG-2 and PLC/PRF/5 hepatoma cells.

scientific article published on January 2013

Neurokinin-1 receptor (NK1R) inhibition sensitizes APL cells to anti-tumor effect of arsenic trioxide via restriction of NF-κB axis: Shedding new light on resistance to Aprepitant

scientific article published on 23 August 2018

Novel pan PI3K inhibitor-induced apoptosis in APL cells correlates with suppression of telomerase: An emerging mechanism of action of BKM120.

scientific article

OPN b and c Isoforms Doubtless Veto Anti-angiogenesis Effects of Curcumin in Combination with Conventional AML Regiment

scientific article published on 27 September 2017

Osteopontin b and c Splice isoforms in Leukemias and Solid Tumors: Angiogenesis Alongside Chemoresistance

scientific article published on 27 March 2018

Osteopontin b and c isoforms: Molecular Candidates Associated with Leukemic Stem Cell Chemoresistance in Acute Myeloid Leukemia

Osteopontin plays a unique role in resistance of CD34+/CD123+ human leukemia cell lines KG1a to parthenolide.

scientific article

Overexpression of Endometrial Estrogen Receptor-Alpha in The Window of Implantation in Women with Unexplained Infertility.

scientific article published on 7 January 2018

PARP-1 Overexpression as an Independent Prognostic Factor in Adult Non-M3 Acute Myeloid Leukemia

scientific article published on 29 May 2018

PI3K-δ inhibition using CAL-101 exerts apoptotic effects and increases doxorubicin-induced cell death in pre-B-acute lymphoblastic leukemia cells.

scientific article published on 25 January 2017

Patterns of gene divergence and VL promoter activity in immunoglobulin light chain clusters of the channel catfish.

scientific article

Peripheral blood versus bone marrow as a source of hematopoietic stem cells for allogeneic transplantation in children with class I and II beta thalassemia major.

scientific article

Pharmacological evidence for the involvement of adenosine triphosphate sensitive potassium channels in chloroquine-induced itch in mice

scientific article published on 3 June 2017

Phase II study of single-agent arsenic trioxide for the front-line therapy of acute promyelocytic leukemia.

scientific article published on 6 June 2011

Prognostic and Therapeutic Significance of Androgen Receptor in Patients with Gastric Cancer

scientific article published on 02 October 2020

Reactive oxygen species generation and increase in mitochondrial copy number: new insight into the potential mechanism of cytotoxicity induced by aurora kinase inhibitor, AZD1152-HQPA.

scientific article

Real-time PCR analysis of PML-RAR alpha in newly diagnosed acute promyelocytic leukaemia patients treated with arsenic trioxide as a front-line therapy.

scientific article

Reciprocal Interactions of Leukemic Cells with Bone Marrow Stromal Cells Promote Enrichment of Leukemic Stem Cell Compartments in Response to Curcumin and Daunorubicin

scientific article

Redistribution of cell cycle by arsenic trioxide is associated with demethylation and expression changes of cell cycle related genes in acute promyelocytic leukemia cell line (NB4).

scientific article published on 20 November 2017

Residual methylation of tumor suppressor gene promoters, RASSF6 and RASSF10, as novel biomarkers for minimal residual disease detection in adult acute lymphoblastic leukemia

scientific article published on 05 September 2019

Significance of AZD1152 as a potential treatment against Aurora B overexpression in acute promyelocytic leukemia

scientific article published on 19 April 2016

Small molecule inhibitor of TLR4 inhibits ovarian cancer cell proliferation: new insight into the anticancer effect of TAK-242 (Resatorvid)

scientific article published on 30 November 2019

Survivin isoform expression in arsenic trioxide-treated acute promyelocytic leukemia cell line and patients: The odd expression pattern of survivin-2α.

scientific article published on 22 October 2016

Synergistic effects of arsenic trioxide and silibinin on apoptosis and invasion in human glioblastoma U87MG cell line.

scientific article published on 4 October 2011

TLR4 blockade using TAK-242 suppresses ovarian and breast cancer cells invasion through the inhibition of extracellular matrix degradation and epithelial-mesenchymal transition

scientific article published on 28 March 2019

Targeting human telomerase RNA component using antisense oligonucleotide induces rapid cell death and increases ATO-induced apoptosis in APL cells

scientific article published on 19 May 2017

Targeting of EGFR increase anti-cancer effects of arsenic trioxide: Promising treatment for glioblastoma multiform.

scientific article published on 20 December 2017

Telomerase activity and telomere length in patients with acute promyelocytic leukemia: indicative of proliferative activity, disease progression, and overall survival

scientific article published on 20 June 2008

Teucrium polium reversed the MCD diet-induced liver injury in rats.

scientific article

The Beneficial Effects of Valproic Acid in Thyroid Cancer Are Mediated through Promoting Redifferentiation and Reducing Stemness Level: An In Vitro Study

scientific article

The ERBB receptor inhibitor dacomitinib suppresses proliferation and invasion of pancreatic ductal adenocarcinoma cells

scientific article published on 25 April 2019

The Potential Contribution of microRNAs in Anti-cancer Effects of Aurora Kinase Inhibitor (AZD1152-HQPA)

scientific article published on 26 July 2018

The anticancer effect of the TLR4 inhibition using TAK-242 (resatorvid) either as a single agent or in combination with chemotherapy: A novel therapeutic potential for breast cancer

scientific article published on 18 September 2019

The detection of disseminated tumor cells in bone marrow and peripheral blood of gastric cancer patients by multimarker (CEA, CK20, TFF1 and MUC2) quantitative real-time PCR ⬇️

scientific article published on December 1, 2010

The expression of p38, ERK1 and Bax proteins has increased during the treatment of newly diagnosed acute promyelocytic leukemia with arsenic trioxide.

scientific article published on 17 February 2010

The influence of the HLA-DRB1 and HLA-DQB1 allele heterogeneity on disease risk and severity in Iranian patients with multiple sclerosis

scientific article published on 09 March 2012

The inhibitory effect of disulfiram encapsulated PLGA NPs on tumor growth: Different administration routes

scientific article published on 09 March 2016

The role of toll-like receptor 4 (TLR4) in cancer progression: A possible therapeutic target?

scientific article published on 23 November 2020

Therapeutic Efficacy of Silibinin on Human Neuroblastoma Cells: Akt and NF-κB Expressions May Play an Important Role in Silibinin-Induced Response ⬇️

scientific article published on June 21, 2012

Tropisetron suppresses colitis-associated cancer in a mouse model in the remission stage

scientific article

Why have microRNA biomarkers not been translated from bench to clinic?

scientific article published on 17 January 2019

Paulina is supported by:

About Paulina

Help