List of works - D. Eric Walters

A conserved arginine near the filter of Kir1.1 controls Rb/K selectivity.

scientific article

Active conformations of neotame and other high-potency sweeteners

scientific article published on 01 March 2000

An intersubunit salt bridge near the selectivity filter stabilizes the active state of Kir1.1.

scientific article published on August 2009

Antipsychotics inhibit glucose transport: Determination of olanzapine binding site in Staphylococcus epidermidis glucose/H(+) symporter.

scientific article published on 15 April 2015

Binding of glutamate to the umami receptor.

scientific article published on 26 September 2010

Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation.

scientific article

Design and synthesis of potent macrocyclic HIV-1 protease inhibitors involving P1-P2 ligands.

scientific article

External K activation of Kir1.1 depends on the pH gate

scientific article published on 11 May 2007

Genetically evolved receptor models: a computational approach to construction of receptor models.

scientific article published in August 1994

Identification of the substrate binding sites within the yeast mitochondrial citrate transport protein

scientific article published on 30 March 2007

Inhibitors of the mitochondrial citrate transport protein: validation of the role of substrate binding residues and discovery of the first purely competitive inhibitor.

scientific article

Introduction of the chloroplast redox regulatory region in the yeast ATP synthase impairs cytochrome c oxidase.

scientific article

Ion selectivity of alpha-hemolysin with beta-cyclodextrin adapter. II. Multi-ion effects studied with grand canonical Monte Carlo/Brownian dynamics simulations.

scientific article

Microbial transformations of antitumor compounds. 1. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata ⬇️

scientific article published on June 1, 1974

Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis

scientific article

Molecular dynamics study of a polymeric reverse osmosis membrane

scientific article published on 01 July 2009

N,N'-disubstituted guanidine high-potency sweeteners

scientific article published on February 21, 1992

Oligomeric state of wild-type and cysteine-less yeast mitochondrial citrate transport proteins

scientific article published on 01 December 1999

Oligomycin frames a common drug-binding site in the ATP synthase.

scientific article

Orexin Antagonists: A Wake-Up Call for Medicinal Chemists?

scientific article published on 19 February 2020

Potent HIV-1 protease inhibitors incorporating squaramide-derived P2 ligands: Design, synthesis, and biological evaluation

scientific article published on 05 August 2019

Predictive models of protein-active sites

scientific article published on 01 January 2000

Presence of the anti-leukemic nucleotide analog, 2-chloro-2'-deoxyadenosine-5'-monophosphate, in a promoter sequence alters DNA binding of TATA-binding protein (TBP).

scientific article published on 24 January 2007

Probing the effect of transport inhibitors on the conformation of the mitochondrial citrate transport protein via a site-directed spin labeling approach.

scientific article

Properties of two cataract-associated mutations located in the NH2 terminus of connexin 46.

scientific article published on 9 January 2013

Regulation of ROMK by extracellular cations

scientific article

Structural locus of the pH gate in the Kir1.1 inward rectifier channel.

scientific article

Structure and dynamic behavior of the oligosaccharide side chain of bovine pancreatic ribonuclease B. Application of carbon 13 nuclear magnetic resonance spectroscopy

scientific article published on 01 April 1981

Structure-based design: synthesis and biological evaluation of a series of novel cycloamide-derived HIV-1 protease inhibitors.

scientific article

Tautomeric states of the histidine residues of bovine pancreatic ribonuclease A. Application of carbon 13 nuclear magnetic resonance spectroscopy

scientific article published on 01 July 1980

Team-based learning applied to a medicinal chemistry course

scientific article published on 20 September 2012

The active site of pyrophosphate-dependent phosphofructo-1-kinase based on site-directed mutagenesis and molecular modeling

scientific article published on 01 January 1998

The mitochondrial citrate transport protein: evidence for a steric interaction between glutamine 182 and leucine 120 and its relationship to the substrate translocation pathway and identification of other mechanistically essential residues.

scientific article published on 29 June 2006

The mitochondrial citrate transport protein: probing the secondary structure of transmembrane domain III, identification of residues that likely comprise a portion of the citrate transport pathway, and development of a model for the putative [...]

scientific article

The yeast mitochondrial citrate transport protein. Probing the roles of cysteines, Arg(181), and Arg(189) in transporter function

scientific article

The yeast mitochondrial citrate transport protein. Probing the secondary structure of transmembrane domain iv and identification of residues that likely comprise a portion of the citrate translocation pathway

scientific article published on 01 April 2000

The yeast mitochondrial citrate transport protein: determination of secondary structure and solvent accessibility of transmembrane domain IV using site-directed spin labeling

scientific article published on 01 August 2000

The yeast mitochondrial citrate transport protein: identification of the Lysine residues responsible for inhibition mediated by Pyridoxal 5'-phosphate.

scientific article

Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases.

scientific article published on 12 October 2016

List of works by D. Eric Walters

A conserved arginine near the filter of Kir1.1 controls Rb/K selectivity.

Active conformations of neotame and other high-potency sweeteners

An intersubunit salt bridge near the selectivity filter stabilizes the active state of Kir1.1.

Antipsychotics inhibit glucose transport: Determination of olanzapine binding site in Staphylococcus epidermidis glucose/H(+) symporter.

Binding of glutamate to the umami receptor.

Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation.

Design and synthesis of potent macrocyclic HIV-1 protease inhibitors involving P1-P2 ligands.

External K activation of Kir1.1 depends on the pH gate

Genetically evolved receptor models: a computational approach to construction of receptor models.

Identification of the substrate binding sites within the yeast mitochondrial citrate transport protein

Inhibitors of the mitochondrial citrate transport protein: validation of the role of substrate binding residues and discovery of the first purely competitive inhibitor.

Introduction of the chloroplast redox regulatory region in the yeast ATP synthase impairs cytochrome c oxidase.

Ion selectivity of alpha-hemolysin with beta-cyclodextrin adapter. II. Multi-ion effects studied with grand canonical Monte Carlo/Brownian dynamics simulations.

Microbial transformations of antitumor compounds. 1. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata ⬇️

Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis

Molecular dynamics study of a polymeric reverse osmosis membrane

N,N'-disubstituted guanidine high-potency sweeteners

Oligomeric state of wild-type and cysteine-less yeast mitochondrial citrate transport proteins

Oligomycin frames a common drug-binding site in the ATP synthase.

Orexin Antagonists: A Wake-Up Call for Medicinal Chemists?

Potent HIV-1 protease inhibitors incorporating squaramide-derived P2 ligands: Design, synthesis, and biological evaluation

Predictive models of protein-active sites

Presence of the anti-leukemic nucleotide analog, 2-chloro-2'-deoxyadenosine-5'-monophosphate, in a promoter sequence alters DNA binding of TATA-binding protein (TBP).

Probing the effect of transport inhibitors on the conformation of the mitochondrial citrate transport protein via a site-directed spin labeling approach.

Properties of two cataract-associated mutations located in the NH2 terminus of connexin 46.

Regulation of ROMK by extracellular cations

Structural locus of the pH gate in the Kir1.1 inward rectifier channel.

Structure and dynamic behavior of the oligosaccharide side chain of bovine pancreatic ribonuclease B. Application of carbon 13 nuclear magnetic resonance spectroscopy

Structure-based design: synthesis and biological evaluation of a series of novel cycloamide-derived HIV-1 protease inhibitors.

Tautomeric states of the histidine residues of bovine pancreatic ribonuclease A. Application of carbon 13 nuclear magnetic resonance spectroscopy

Team-based learning applied to a medicinal chemistry course

The active site of pyrophosphate-dependent phosphofructo-1-kinase based on site-directed mutagenesis and molecular modeling

The mitochondrial citrate transport protein: evidence for a steric interaction between glutamine 182 and leucine 120 and its relationship to the substrate translocation pathway and identification of other mechanistically essential residues.

The mitochondrial citrate transport protein: probing the secondary structure of transmembrane domain III, identification of residues that likely comprise a portion of the citrate transport pathway, and development of a model for the putative [...]

The yeast mitochondrial citrate transport protein. Probing the roles of cysteines, Arg(181), and Arg(189) in transporter function

The yeast mitochondrial citrate transport protein. Probing the secondary structure of transmembrane domain iv and identification of residues that likely comprise a portion of the citrate translocation pathway

The yeast mitochondrial citrate transport protein: determination of secondary structure and solvent accessibility of transmembrane domain IV using site-directed spin labeling

The yeast mitochondrial citrate transport protein: identification of the Lysine residues responsible for inhibition mediated by Pyridoxal 5'-phosphate.

Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases.