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List of works by Jian-Dong Huang

'Obligate' anaerobic Salmonella strain YB1 suppresses liver tumor growth and metastasis in nude mice.

scientific article

A DNA vaccine targeting TcdA and TcdB induces protective immunity against Clostridium difficile

scientific article

A SIRT1-centered circuitry regulates breast cancer stemness and metastasis

scientific article published on 23 July 2018

A modified formulation of Huanglian-Jie-Du-Tang reduces memory impairments and β-amyloid plaques in a triple transgenic mouse model of Alzheimer's disease

scientific article published on 24 July 2017

A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating

scientific article published on 25 December 2018

A novel galactose-PEG-conjugated biodegradable copolymer is an efficient gene delivery vector for immunotherapy of hepatocellular carcinoma

scientific article published on 01 September 2018

A regulatory polymorphism in interferon-gamma receptor 1 promoter is associated with the susceptibility to chronic hepatitis B virus infection.

scientific article

A splice-site mutation leads to haploinsufficiency of EXT2 mRNA for a dominant trait in a large family with multiple osteochondromas

scientific article published on 01 November 2010

Adipose-specific deletion of Kif5b exacerbates obesity and insulin resistance in a mouse model of diet-induced obesity.

scientific article published on 27 February 2017

Amyloid Pathology in Spinal Cord of the Transgenic Alzheimer's Disease Mice is Correlated to the Corticospinal Tract Pathway ⬇️

scientific article published on January 1, 2013

Analysis of Kif5b expression during mouse kidney development.

scientific article

Angiogenic inhibitors delivered by the type III secretion system of tumor-targeting Salmonella typhimurium safely shrink tumors in mice

scientific article published on 24 August 2016

Association of candidate susceptible loci with chronic infection with hepatitis B virus in a Chinese population

article

Cell death caused by single-stranded oligodeoxynucleotide-mediated targeted genomic sequence modification.

scientific article

Conventional kinesin KIF5B mediates adiponectin secretion in 3T3-L1 adipocytes

scientific article

Decrease in the Generation of Amyloid-β Due to Salvianolic Acid B by Modulating BACE1 Activity

scientific article published on 17 April 2017

Decreased c-Jun expression correlates with impaired spinal motoneuron regeneration in aged mice following sciatic nerve crush ⬇️

scientific article published on February 22, 2012

Dissect Kif5b in nuclear positioning during myogenesis: the light chain binding domain and the autoinhibitory peptide are both indispensable.

scientific article published on 10 February 2013

Efficient and seamless DNA recombineering using a thymidylate synthase A selection system in Escherichia coli

scientific article

Engineering a portable riboswitch-LacP hybrid device for two-way gene regulation ⬇️

scientific article published on July 29, 2011

Establishment of a lethal aged mouse model of human respiratory syncytial virus infection

scientific article published on 29 November 2018

Expression and characterization of a histidine-rich protein, Hpn: potential for Ni2+ storage in Helicobacter pylori.

scientific article published on January 2006

Family-Specific Training Improves Linear B Cell Epitope Prediction for Emerging Viruses

scientific article published on 04 September 2023

Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region ⬇️

scientific article published on October 1, 1991

Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection.

scientific article

Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma.

scientific article

Genomic instability in laminopathy-based premature aging

scientific article

Hippocampal metabolomics using ultrahigh-resolution mass spectrometry reveals neuroinflammation from Alzheimer's disease in CRND8 mice.

scientific article published on 14 March 2013

Identification of Drug Resistant Mutations in HIV-1 CRF07_BC Variants Selected by Nevirapine In Vitro ⬇️

scientific article published on September 12, 2012

Identification of factors influencing strand bias in oligonucleotide-mediated recombination in Escherichia coli ⬇️

scientific article published on November 15, 2003

Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection.

scientific article

Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics.

scientific article published in September 2004

Immunotherapy Targeting Adenosine Synthase A Decreases Severity of Staphylococcus aureus Infection in Mouse Model.

scientific article published on 13 June 2017

In vitro selection of HIV-1 CRF08_BC variants resistant to reverse transcriptase inhibitors.

scientific article published on 8 January 2015

Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression.

scientific article

Inhibition of HBV gene expression and replication by stably expressed interferon-alpha1 via adeno-associated viral vectors.

scientific article

Inhibition of SARS coronavirus helicase by bismuth complexes.

scientific article published on 16 August 2007

Intradermal delivery of receptor-binding domain of SARS-CoV-2 spike protein with dissolvable microneedles to induce humoral and cellular responses in mice

scientific article published on 12 December 2020

Kif5b controls the localization of myofibril components for their assembly and linkage to the myotendinous junctions.

scientific article published in February 2013

Kinesin-1 Regulates Extrasynaptic Targeting of NMDARs and Neuronal Vulnerability Toward Excitotoxicity

scientific article published on 18 February 2019

Kinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex

scientific article published on October 2016

Kinesin-1 regulates antigen cross-presentation through the scission of tubulations from early endosomes in dendritic cells

scientific article published on 14 April 2020

Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus.

scientific article published on 30 March 2006

Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin

scientific article

Live attenuated Salmonella typhimurium vaccines delivering SaEsxA and SaEsxB via type III secretion system confer protection against Staphylococcus aureus infection.

scientific article published on 25 April 2018

Mapping the Immunodominance Landscape of SARS-CoV-2 Spike Protein for the Design of Vaccines against COVID-19

scientific article published on 24 April 2020

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells ⬇️

scientific article published on September 22, 2011

Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients

scientific article published on 01 July 2020

Modification of the RpoS network with a synthetic small RNA.

scientific article

Multimodal nonlinear optical microscopy reveals critical role of kinesin-1 in cartilage development.

scientific article

PICK1 is Essential for Insulin Production and the Maintenance of Glucose Homeostasis.

scientific article published on 3 January 2018

PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway

scientific article published on 02 July 2020

Portable two-way riboswitches: design and engineering

scientific article

Recent Strategies to Combat Biofilms Using Antimicrobial Agents and Therapeutic Approaches

scientific article published in 2022

Recombinant ESAT-6-like proteins provoke protective immune responses against invasive Staphylococcus aureus disease in a murine model

scientific article

SARS-CoV-2 infects human neural progenitor cells and brain organoids

scientific article published on 04 August 2020

Salvianolic acid B inhibits Abeta fibril formation and disaggregates preformed fibrils and protects against Abeta-induced cytotoxicty.

scientific article

Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling

scientific article

Single-stranded oligonucleotide-mediated gene repair in mammalian cells has a mechanism distinct from homologous recombination repair.

scientific article published on 26 September 2006

Small interfering RNA targeting m2 gene induces effective and long term inhibition of influenza A virus replication.

scientific article

Small noncoding RNA GcvB is a novel regulator of acid resistance in Escherichia coli

scientific article

Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

scientific article published on 21 January 2020

Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection.

scientific article published on 10 October 2008

Stable knockdown of Kif5b in MDCK cells leads to epithelial-mesenchymal transition.

scientific article published on 20 May 2015

Stripe formation in bacterial systems with density-suppressed motility

scientific article published on 08 May 2012

Super-resolution imaging of a 2.5 kb non-repetitive DNA in situ in the nuclear genome using molecular beacon probes.

scientific article

The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus.

scientific article published in March 2005

The effect of salvianolic acid B combined with laminar shear stress on TNF-alpha-stimulated adhesion molecule expression in human aortic endothelial cells

scientific article published on 01 January 2010

The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression.

scientific article published in April 1993

The involvement of replication in single stranded oligonucleotide-mediated gene repair.

scientific article

The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5' to 3' viral helicases.

scientific article published on 13 August 2003

The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression.

scientific article published on December 1995

Treatment of Neuroblastoma with an Engineered "Obligate" Anaerobic Salmonella typhimurium Strain YB1.

scientific article

Ultrahigh resolution mass spectrometry-based metabolic characterization reveals cerebellum as a disturbed region in two animal models.

scientific article published on 5 October 2013

Urinary Metabolomics Reveals Alterations of Aromatic Amino Acid Metabolism of Alzheimer's Disease in the Transgenic CRND8 Mice.

scientific article published on 28 January 2016

Use of a riboswitch-controlled conditional hypomorphic mutation to uncover a role for the essential csrA gene in bacterial autoaggregation.

scientific article published on 25 August 2009

Visualizing the proteome of Escherichia coli: an efficient and versatile method for labeling chromosomal coding DNA sequences (CDSs) with fluorescent protein genes

scientific article published on 31 January 2007

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