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List of works by Sandrine Silvente-Poirot

A fast UPLC-HILIC method for an accurate quantification of dendrogenin A in human tissues

scientific article published on 12 August 2019

A segment of five amino acids in the second extracellular loop of the cholecystokinin-B receptor is essential for selectivity of the peptide agonist gastrin

scientific article

Arginine 197 of the cholecystokinin-A receptor binding site interacts with the sulfate of the peptide agonist cholecystokinin

scientific article

Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors.

scientific article published on 11 August 2010

Bryonolic Acid Blocks Cancer Cell Clonogenicity and Invasiveness through the Inhibition of Fatty Acid: Cholesteryl Ester Formation.

scientific article published on 12 February 2018

Cancer. Cholesterol and cancer, in the balance

scientific article published on 01 March 2014

Chemistry, biochemistry, metabolic fate and mechanism of action of 6-oxo-cholestan-3β,5α-diol (OCDO), a tumor promoter and cholesterol metabolite.

scientific article published on 11 April 2018

Cholesterol metabolism and cancer: the good, the bad and the ugly

scientific article published on 26 October 2012

Cholesterol metabolism and resistance to tamoxifen.

scientific article published on 11 October 2012

Cholesterol-5,6-epoxides: chemistry, biochemistry, metabolic fate and cancer.

scientific article published on 18 May 2012

Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study.

scientific article published on 22 June 2016

Dendrogenin A and B two new steroidal alkaloids increasing neural responsiveness in the deafened guinea pig.

scientific article published on 24 July 2015

Dendrogenin A drives LXR to trigger lethal autophagy in cancers.

scientific article published on 4 December 2017

Dendrogenin A: A Mammalian Metabolite of Cholesterol with Tumor Suppressor and Neurostimulating Properties

scientific article published on 16 July 2015

Development of a new radioligand for cholecystokinin receptor subtype 2 scintigraphy: from molecular modeling to in vivo evaluation.

scientific article published on 19 May 2010

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins.

scientific article

Exosomes as intercellular signalosomes and pharmacological effectors.

scientific article published on March 2011

Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies.

scientific article published on 16 October 2013

Extracellular vesicles: lipids as key components of their biogenesis and functions

scientific article published on 15 May 2018

Flavonoids differentially modulate liver X receptors activity-Structure-function relationship analysis

scientific article published on 05 April 2019

From tamoxifen to dendrogenin A: The discovery of a mammalian tumor suppressor and cholesterol metabolite.

scientific article published on June 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HPLC Analysis and Skin Whitening Effects of Umbelliprenin-containing Extracts of , , and

scientific article published on 30 January 2019

High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor.

scientific article published on September 2003

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

scientific article

Improvement of 5,6α-epoxycholesterol, 5,6β-epoxycholesterol, cholestane-3β,5α,6β-triol and 6-oxo-cholestan-3β,5α-diol recovery for quantification by GC/MS.

scientific article published on 26 May 2017

Improving the efficacy of hormone therapy in breast cancer: The role of cholesterol metabolism in SERM-mediated autophagy, cell differentiation and death

scientific article

Insights into the cholecystokinin 2 receptor binding site and processes of activation

scientific article published on 22 September 2006

Ligand-induced internalization of cholecystokinin receptors. Demonstration of the importance of the carboxyl terminus for ligand-induced internalization of the rat cholecystokinin type B receptor but not the type A receptor.

scientific article published on July 1997

Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism.

scientific article

Molecular and Biochemical Analysis of the Estrogenic and Proliferative Properties of Vitamin E Compounds.

scientific article

Mutation of Asn-391 within the conserved NPXXY motif of the cholecystokinin B receptor abolishes Gq protein activation without affecting its association with the receptor

scientific article published on 01 June 2000

Natural and semisynthetic oxyprenylated aromatic compounds as stimulators or inhibitors of melanogenesis

scientific article published on 14 March 2019

One step synthesis of 6-oxo-cholestan-3β,5α-diol.

scientific article published on 4 February 2014

Oxysterols: An expanding family of structurally diversified bioactive steroids

scientific article published on 31 July 2019

Quantitative analysis of the tumor suppressor dendrogenin A using liquid chromatography tandem mass spectrometry.

scientific article

Role of the extracellular domains of the cholecystokinin receptor in agonist binding.

scientific article

Structure of cholecystokinin receptor binding sites and mechanism of activation/inactivation by agonists/antagonists.

scientific article published in December 2002

Study of the states and populations of the rat pancreatic cholecystokinin receptor using the full peptide antagonist JMV 179

scientific article published on 01 March 1993

Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases.

scientific article published on December 2009

Synthesis, characterization and in vitro evaluation of new oxorhenium- and oxotechnetium-CCK4 derivatives as molecular imaging agents for CCK2-receptor targeting.

scientific article published on 8 October 2009

Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation.

scientific article

Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells.

scientific article published on 14 November 2003

Technical note: Hapten synthesis, antibody production and development of an enzyme-linked immunosorbent assay for detection of the natural steroidal alkaloid Dendrogenin A.

scientific article

The Effects of Cholesterol-Derived Oncometabolites on Nuclear Receptor Function in Cancer

scientific article published on 17 August 2018

The cholesterol-derived metabolite dendrogenin A functionally reprograms breast adenocarcinoma and undifferentiated thyroid cancer cells

scientific article published on 03 June 2019

The novel steroidal alkaloids dendrogenin A and B promote proliferation of adult neural stem cells

scientific article published on 06 January 2014

The prototypical inhibitor of cholesterol esterification, Sah 58-035 [3-[decyldimethylsilyl]-n-[2-(4-methylphenyl)-1-phenylethyl]propanamide], is an agonist of estrogen receptors.

scientific article published on 11 July 2006

The third intracellular loop of the rat and mouse cholecystokinin-A receptors is responsible for different patterns of gene activation

scientific article published on 01 December 2000

The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers.

scientific article published on 31 January 2018

When cholesterol meets histamine, it gives rise to dendrogenin A: a tumour suppressor metabolite

scientific article published on April 2016

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