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List of works by Jan Bauer

A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model

scientific article published on 11 July 2017

A comparative analysis of B cell-mediated myelin oligodendrocyte glycoprotein-experimental autoimmune encephalomyelitis pathogenesis in B cell-deficient mice reveals an effect on demyelination

scientific article published on 01 July 2002

A new primate model for multiple sclerosis in the common marmoset

scientific article published on 01 June 2000

A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice

scientific article published on 01 March 1999

Acute cerebral white matter damage in lethal salicylate intoxication

scientific article (publication date: 2007)

After injection into the striatum, in vitro-differentiated microglia- and bone marrow-derived dendritic cells can leave the central nervous system via the blood stream.

scientific article published on 30 October 2008

Antibodies against human BLyS and APRIL attenuate EAE development in marmoset monkeys.

scientific article published on 30 June 2012

Apoptosis-inducing factor in nigral dopamine neurons: Higher levels in primates than in mice

scientific article

Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination

scientific article (publication date: 27 January 2017)

Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis

scientific article

Autoimmune encephalitis in humans: how closely does it reflect multiple sclerosis ?

scientific article

Autoimmune epilepsies

scientific article published on April 2014

Autoimmunity against myelin oligodendrocyte glycoprotein is dispensable for the initiation although essential for the progression of chronic encephalomyelitis in common marmosets

scientific article published on 01 April 2008

B-cell depletion abrogates T cell-mediated demyelination in an antibody-nondependent common marmoset experimental autoimmune encephalomyelitis model.

scientific article published in August 2012

B-cell depletion attenuates white and gray matter pathology in marmoset experimental autoimmune encephalomyelitis.

scientific article published in November 2011

Blockade of CD127 Exerts a Dichotomous Clinical Effect in Marmoset Experimental Autoimmune Encephalomyelitis.

scientific article

CCR5 blockade for neuroinflammatory diseases--beyond control of HIV.

scientific article

CD4+ and CD8+ T cells are both needed to induce paraneoplastic neurological disease in a mouse model

scientific article

CD8 T cell responses to myelin oligodendrocyte glycoprotein-derived peptides in humanized HLA-A*0201-transgenic mice.

scientific article published on October 2007

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice.

scientific article

CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome

scientific article published on 18 December 2019

CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model.

scientific article published on 6 September 2016

Cell type-specific Nrf2 expression in multiple sclerosis lesions.

scientific article published on 19 June 2015

Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice

scientific article published on 16 February 2011

Complement-associated neuronal loss in a patient with CASPR2 antibody-associated encephalitis

scientific article

Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatibility complex (MHC) haplotype-related.

scientific article published in December 2006

Cutting edge: Multiple sclerosis-like lesions induced by effector CD8 T cells recognizing a sequestered antigen on oligodendrocytes.

scientific article published on August 2008

Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases.

scientific article

Demonstration of interleukin-1 beta in Lewis rat brain during experimental allergic encephalomyelitis by immunocytochemistry at the light and ultrastructural level

scientific article published on 01 October 1993

Differences in T cell cytotoxicity and cell death mechanisms between progressive multifocal leukoencephalopathy, herpes simplex virus encephalitis and cytomegalovirus encephalitis.

scientific article

Discrepant effects of human interferon-gamma on clinical and immunological disease parameters in a novel marmoset model for multiple sclerosis.

scientific article published on 20 October 2011

Disease-specific molecular events in cortical multiple sclerosis lesions.

scientific article published on 17 May 2013

Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis.

scientific article published in September 2006

Effect of annexin-1 on experimental autoimmune encephalomyelitis (EAE) in the rat.

scientific article published in January 1998

Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes.

scientific article published in May 2003

Endotoxin-induced appearance of immunoreactive interleukin-1β in ramified microglia in rat brain: A light and electron microscopic study ⬇️

scientific article published on April 1, 1995

Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice.

scholarly article

Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself

scientific article published on 06 June 2016

Fast progression of recombinant human myelin/oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis in marmosets is associated with the activation of MOG34-56-specific cytotoxic T cells

scientific article published on 01 February 2008

Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis.

scientific article

Hypothalamic immunopathology in anti-Ma-associated diencephalitis with narcolepsy-cataplexy.

scientific article published on October 2013

IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration

scientific article published on 04 April 2019

IgG and complement deposition and neuronal loss in cats and humans with epilepsy and voltage-gated potassium channel complex antibodies

scientific article published on May 2014

Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund's adjuvant

scientific article

Immune-complex-trapping cells in the spleen of the oriental fire-bellied toad, Bombina orientalis.

scientific article published in January 1993

In situ expansion of T cells that recognize distinct self-antigens sustains autoimmunity in the CNS.

scientific article published on 21 March 2016

Induction of Experimental Autoimmune Encephalomyelitis With Recombinant Human Myelin Oligodendrocyte Glycoprotein in Incomplete Freund’s Adjuvant in Three Non-human Primate Species ⬇️

scientific article published on 03 July 2013

Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination.

scientific article published on 8 June 2010

Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death.

scientific article

Innate and adaptive immunity in human epilepsies

scientific article published on July 2017

Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis

scientific article

Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats

scientific article published on 08 May 2013

Invariant NKT cells regulate the CD8 T cell response during Theiler's virus infection

scientific article published on 30 January 2014

Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?

scientific article (publication date: 5 April 2007)

Microglial nodules provide the environment for pathogenic T cells in human encephalitis

scientific article published on 20 January 2019

NG2 plays a role in neuroinflammation but is not expressed by immune cells.

scientific article published on 31 May 2017

Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo.

scientific article

Neuropathological Techniques to Investigate Central Nervous System Sections in Multiple Sclerosis

scientific article

Neuropathology of autoimmune encephalitides.

scientific article published on January 2016

Neuroprotection requires the functions of the RNA-binding protein HuR.

scientific article

Non-human primate models of experimental autoimmune encephalomyelitis: Variations on a theme.

scientific article

Non-invasive measurement of brain damage in a primate model of multiple sclerosis.

scientific article

Non‐human primate models of multiple sclerosis ⬇️

scientific article published on October 1, 2001

Notch1 and its ligand Jagged1 are present in remyelination in a T-cell- and antibody-mediated model of inflammatory demyelination.

scientific article published on 30 November 2006

Novel Insights into the Distribution and Functional Aspects of the Calcium Binding Protein Secretagogin from Studies on Rat Brain and Primary Neuronal Cell Culture ⬇️

scientific article published on August 6, 2012

Oligodendrocyte-specific protein is encephalitogenic in rhesus macaques and induces specific demyelination of the optic nerve

scientific article published on 01 May 2008

Overview of models, methods, and reagents developed for translational autoimmunity research in the common marmoset (Callithrix jacchus).

scientific article

Oxidative Injury and Iron Redistribution Are Pathological Hallmarks of Marmoset Experimental Autoimmune Encephalomyelitis.

scientific article

Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.

scientific article published on 13 March 2014

Paraneoplastic neuromyelitis optica and ovarian teratoma: A case series

scientific article published on 01 April 2019

Peroxisomal localization of the proopiomelanocortin-derived peptides beta-lipotropin and beta-endorphin

scientific article

Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells.

scientific article published on August 2006

Pharmacochaperoning of the A1 adenosine receptor is contingent on the endoplasmic reticulum.

scientific article published on 10 March 2010

Progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome (IRIS).

scientific article published on September 2015

Proliferation in the Alzheimer hippocampus is due to microglia, not astroglia, and occurs at sites of amyloid deposition

scientific article

Quantitative MRI-pathology correlations of brain white matter lesions developing in a non-human primate model of multiple sclerosis.

scientific article published in April 2007

Rasmussen's encephalitis: a role for autoimmune cytotoxic T lymphocytes.

scientific article published in April 2002

Rasmussen's encephalitis: clinical features, pathobiology, and treatment advances.

scientific article

Re-expression of N-cadherin in remyelinating lesions of experimental inflammatory demyelination

scientific article

Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats

scientific article published on 01 February 1995

Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental autoimmune transferred experimental autoimmune encephalomyelitis: An investigation using rat radiation bone marrow chimeras

scientific article published on 01 August 1995

Rhesus monkeys are highly susceptible to experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein: characterisation of immunodominant T- and B-cell epitopes

scientific article published on 01 October 2000

Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis

scientific article

Selective Limbic Blood-Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies.

scientific article published on 18 October 2017

Selective blockade of CD28-mediated T cell costimulation protects rhesus monkeys against acute fatal experimental autoimmune encephalomyelitis

scientific article published on 14 January 2015

Severe oxidative stress in an acute inflammatory demyelinating model in the rhesus monkey

scientific article published on 14 November 2017

Systematic evaluation of RNA quality, microarray data reliability and pathway analysis in fresh, fresh frozen and formalin-fixed paraffin-embedded tissue samples.

scientific article published on 20 April 2018

T cell-activation in neuromyelitis optica lesions plays a role in their formation.

scientific article published on 24 December 2013

Targeted Diet Modification Reduces Multiple Sclerosis-like Disease in Adult Marmoset Monkeys from an Outbred Colony

scientific article published on 19 October 2018

Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity

scientific article published on 22 July 2009

The Functional Activity of High Endothelial Venules: A Role for the Subcapsular Sinus Macrophages in the Lymph NodeREIN ⬇️

scientific article published on 01 June 1991

The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells.

scientific article

The different clinical effects of anti-BLyS, anti-APRIL and anti-CD20 antibodies point at a critical pathogenic role of γ-herpesvirus infected B cells in the marmoset EAE model.

scientific article published on 19 March 2013

The human CMV-UL86 peptide 981-1003 shares a crossreactive T-cell epitope with the encephalitogenic MOG peptide 34-56, but lacks the capacity to induce EAE in rhesus monkeys.

scientific article published on 28 November 2006

The low density lipoprotein receptor gene family. Differential expression of two alpha2-macroglobulin receptors in the brain

scientific journal article

The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset.

scientific article published on 24 September 2010

The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis

article

Therapeutic use of CCR5 antagonists is supported by strong expression of CCR5 on CD8+ T cells in progressive multifocal leukoencephalopathy-associated immune reconstitution inflammatory syndrome

scientific article published on 15 January 2015

Tissue transglutaminase activity is involved in the differentiation of oligodendrocyte precursor cells into myelin‐forming oligodendrocytes during CNS remyelination ⬇️

scientific article published on July 11, 2011

Transgenic Lewis rats overexpressing the proteolipid protein gene: myelin degeneration and its effect on T cell-mediated experimental autoimmune encephalomyelitis.

scientific article published in June 1999

Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells

scientific article published on 13 January 2020

Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases

scientific article published on August 2004

Which pathomechanism damages the brain in antibody-associated CNS disease?

scientific article published on 20 July 2011

Widespread demyelination in the cerebellar cortex in multiple sclerosis.

scientific article

[Pathophysiology of antibody-associated diseases of the central nervous system].

scientific article

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