List of works - Louis Fabri

A robust robotic high-throughput antibody purification platform.

scientific article published on 24 May 2016

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling

scientific article

CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors

scientific article published on 14 December 2015

Crystal structure of vascular endothelial growth factor-B in complex with a neutralising antibody Fab fragment

scientific article

Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362.

scientific article published on 19 February 2014

DAN is a secreted glycoprotein related to Xenopus cerberus.

scientific article published in October 1998

EphA4 receptor tyrosine kinase is a modulator of onset and disease severity of experimental autoimmune encephalomyelitis (EAE)

scientific article

Evidence for the formation of a heterotrimeric complex of leukaemia inhibitory factor with its receptor subunits in solution ⬇️

scientific article published on August 1, 1997

Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer

scientific article published on 01 December 2015

Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer.

scientific article

Identification of a functional domain of human granulocyte colony-stimulating factor using neutralizing monoclonal antibodies ⬇️

scientific article published on December 15, 1991

Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex.

scientific article

Intravenous Immunoglobulin Protects Against Severe Pandemic Influenza Infection.

scientific article

Intravenous immunglobulin binds beta amyloid and modifies its aggregation, neurotoxicity and microglial phagocytosis in vitro.

scientific article

Mapping of the antibody- and receptor-binding domains of granulocyte colony-stimulating factor using an optical biosensor. Comparison with enzyme-linked immunosorbent assay competition studies

scientific article published on 01 August 1993

Midkine (MK), a retinoic acid (RA)-inducible gene product, produced in E. coli acts on neuronal and HL60 leukemia cells.

scientific article published in January 1993

One-step zero-background IgG reformatting of phage-displayed antibody fragments enabling rapid and high-throughput lead identification.

scientific article

Optimizing high throughput antibody purification by using continuous chromatography media

scientific article published on 25 March 2019

Platelet-derived growth factor stimulates the release of protein kinase A from the cell membrane.

scientific article published on February 1994

Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1

scientific article

Protein engineering and preclinical development of a GM-CSF receptor antibody for the treatment of rheumatoid arthritis

scientific article published on January 2013

SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities

scientific article

SOCS2 negatively regulates growth hormone action in vitro and in vivo

scientific journal article

SOCS2 negatively regulates growth hormone action in vitro and in vivo

Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain

scientific journal article

Stoichiometry, kinetic and binding analysis of the interaction between epidermal growth factor (EGF) and the extracellular domain of the EGF receptor

scientific article published on 01 January 2000

Structural characterisation of native and recombinant forms of the neurotrophic cytokine MK

scientific article

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

scientific article published on June 2000

Synergies between micropreparative high-performance liquid chromatography and an instrumental optical biosensor

scientific article published on 01 February 1994

Targeting of acute myeloid leukemia in vitro and in vivo with an anti-CD123 mAb engineered for optimal ADCC.

scientific article published on 7 April 2014

The N-terminus of gp130 is critical for the formation of the high-affinity interleukin-6 receptor complex.

scientific article published in January 1999

The core domain of hepatitis C virus glycoprotein E2 generates potent cross-neutralizing antibodies in guinea pigs

scientific article

The purification of a Rap1 GTPase-activating protein from bovine brain cytosol ⬇️

scientific article published on January 25, 1992

rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs.

scientific article published on 12 March 2018

List of works by Louis Fabri

A robust robotic high-throughput antibody purification platform.

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling

CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors

Crystal structure of vascular endothelial growth factor-B in complex with a neutralising antibody Fab fragment

Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362.

DAN is a secreted glycoprotein related to Xenopus cerberus.

EphA4 receptor tyrosine kinase is a modulator of onset and disease severity of experimental autoimmune encephalomyelitis (EAE)

Evidence for the formation of a heterotrimeric complex of leukaemia inhibitory factor with its receptor subunits in solution ⬇️

Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer

Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer.

Identification of a functional domain of human granulocyte colony-stimulating factor using neutralizing monoclonal antibodies ⬇️

Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex.

Intravenous Immunoglobulin Protects Against Severe Pandemic Influenza Infection.

Intravenous immunglobulin binds beta amyloid and modifies its aggregation, neurotoxicity and microglial phagocytosis in vitro.

Mapping of the antibody- and receptor-binding domains of granulocyte colony-stimulating factor using an optical biosensor. Comparison with enzyme-linked immunosorbent assay competition studies

Midkine (MK), a retinoic acid (RA)-inducible gene product, produced in E. coli acts on neuronal and HL60 leukemia cells.

One-step zero-background IgG reformatting of phage-displayed antibody fragments enabling rapid and high-throughput lead identification.

Optimizing high throughput antibody purification by using continuous chromatography media

Platelet-derived growth factor stimulates the release of protein kinase A from the cell membrane.

Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1

Protein engineering and preclinical development of a GM-CSF receptor antibody for the treatment of rheumatoid arthritis

SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities

SOCS2 negatively regulates growth hormone action in vitro and in vivo

SOCS2 negatively regulates growth hormone action in vitro and in vivo

Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain

Stoichiometry, kinetic and binding analysis of the interaction between epidermal growth factor (EGF) and the extracellular domain of the EGF receptor

Structural characterisation of native and recombinant forms of the neurotrophic cytokine MK

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

Synergies between micropreparative high-performance liquid chromatography and an instrumental optical biosensor

Targeting of acute myeloid leukemia in vitro and in vivo with an anti-CD123 mAb engineered for optimal ADCC.

The N-terminus of gp130 is critical for the formation of the high-affinity interleukin-6 receptor complex.

The core domain of hepatitis C virus glycoprotein E2 generates potent cross-neutralizing antibodies in guinea pigs

The purification of a Rap1 GTPase-activating protein from bovine brain cytosol ⬇️

rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs.