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List of works by Shigeru Tanaka

A brain-specific Grb2-associated regulator of extracellular signal-regulated kinase (Erk)/mitogen-activated protein kinase (MAPK) (GAREM) subtype, GAREM2, contributes to neurite outgrowth of neuroblastoma cells by regulating Erk signaling

scientific article published on 03 September 2013

Adenovirus-mediated gene transfer of heparin-binding epidermal growth factor-like growth factor enhances neurogenesis and angiogenesis after focal cerebral ischemia in rats.

scientific article published on 3 March 2005

Amelioration of hippocampal neuronal damage after transient forebrain ischemia in cyclooxygenase-2-deficient mice

scientific article published in January 2004

Antibody against the carboxyl terminus of the F2 subunit of Sendai virus fusion glycoprotein inhibits proteolytic activation.

scientific article published in June 1993

Bcl2 enhances survival of newborn neurons in the normal and ischemic hippocampus

scientific article published in November 2006

CRE-mediated gene transcription in the peri-infarct area after focal cerebral ischemia in mice

scientific article published on 01 February 2004

Component of nicotine-induced intracellular calcium elevation mediated through α3- and α5-containing nicotinic acetylcholine receptors are regulated by cyclic AMP in SH-SY 5Y cells

scientific article published on 30 November 2020

Congo red, an amyloid-inhibiting compound, alleviates various types of cellular dysfunction triggered by mutant protein kinase cγ that causes spinocerebellar ataxia type 14 (SCA14) by inhibiting oligomerization and aggregation

scientific article published in January 2010

Deregulation of the actin cytoskeleton and macropinocytosis in response to phorbol ester by the mutant protein kinase C gamma that causes spinocerebellar ataxia type 14.

scientific article published on April 2014

Detailed neuronal distribution of GPR3 and its co-expression with EF-hand calcium-binding proteins in the mouse central nervous system

scientific article published on 16 October 2020

Developmental expression of GPR3 in rodent cerebellar granule neurons is associated with cell survival and protects neurons from various apoptotic stimuli

scientific article published on 24 April 2014

Differential Akt phosphorylation at Ser473 and Thr308 in cultured neurons after exposure to glutamate in rats

scientific article published in November 2002

Effect of trehalose on the properties of mutant {gamma}PKC, which causes spinocerebellar ataxia type 14, in neuronal cell lines and cultured Purkinje cells.

scientific article

Effects of the chemical chaperone 4-phenylbutylate on the function of the serotonin transporter (SERT) expressed in COS-7 cells.

scientific article published on 16 May 2013

Establishment of a novel fluorescence-based method to evaluate chaperone-mediated autophagy in a single neuron.

scientific article

Extracellular ATP differentially modulates Toll-like receptor 4-mediated cell survival and death of microglia.

scientific article published on 28 January 2011

Histone deacetylase 10 knockout activates chaperone-mediated autophagy and accelerates the decomposition of its substrate

scientific article published on 18 December 2019

Hypoxic stress activates chaperone-mediated autophagy and modulates neuronal cell survival.

scientific article published on 27 January 2012

Implication of cyclooxygenase-2 on enhanced proliferation of neural progenitor cells in the adult mouse hippocampus after ischemia.

scientific article published in May 2003

Increased proliferation of neural progenitor cells but reduced survival of newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats

scientific article published in March 2002

Induction of the HSP110/105 family in the rat hippocampus in cerebral ischemia and ischemic tolerance.

scientific article published in July 2001

Infiltrating macrophages as in vivo targets for intravenous gene delivery in cerebral infarction

scientific article published on 10 June 2004

Long-term exposure of RN46A cells expressing serotonin transporter (SERT) to a cAMP analog up-regulates SERT activity and is accompanied by neural differentiation of the cells

scientific article published on 26 December 2012

Modifications of tau protein after cerebral ischemia and reperfusion in rats are similar to those occurring in Alzheimer's disease - Hyperphosphorylation and cleavage of 4- and 3-repeat tau.

scientific article published in January 2016

Mutant protein kinase C gamma that causes spinocerebellar ataxia type 14 (SCA14) is selectively degraded by autophagy.

scientific article published on 11 April 2010

Mutant γPKC that causes spinocerebellar ataxia type 14 upregulates Hsp70, which protects cells from the mutant's cytotoxicity

scientific article published on 8 September 2013

Propofol induced diverse and subtype-specific translocation of PKC families.

scientific article published on 6 April 2018

Propofol induces the elevation of intracellular calcium via morphological changes in intracellular organelles, including the endoplasmic reticulum and mitochondria

scientific article published on 15 July 2020

Protective effect of apolipoprotein E against ischemic neuronal injury is mediated through antioxidant action.

scientific article

Purification of a trypsin-type protease from human umbilical vein endothelial cells which is highly sensitive to the Kunitz inhibitor domain peptide of Alzheimer's disease amyloid protein precursor.

scientific article published on January 1993

Regulation of meiotic prophase arrest in mouse oocytes by GPR3, a constitutive activator of the Gs G protein

scientific article

Role of the E3 ubiquitin ligase HRD1 in the regulation of serotonin transporter function

scientific article published on 23 November 2020

SKF-10047, a prototype Sigma-1 receptor agonist, augmented the membrane trafficking and uptake activity of the serotonin transporter and its C-terminus-deleted mutant via a Sigma-1 receptor-independent mechanism

scientific article published on 24 November 2018

Spinocerebellar ataxia type 14 caused by a nonsense mutation in the PRKCG gene

scientific article published on 31 May 2019

Synergistic induction of HSP40 and HSC70 in the mouse hippocampal neurons after cerebral ischemia and ischemic tolerance in gerbil hippocampus

scientific article published in January 2002

The Development of Screening Methods to Identify Drugs to Limit ER Stress Using Wild-type and Mutant Serotonin Transporter

scientific article (publication date: 28 December 2016)

The Gs-linked receptor GPR3 inhibits the proliferation of cerebellar granule cells during postnatal development

scientific article

The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes

scientific article

The Role of Cysteine String Protein α Phosphorylation at Serine 10 and 34 by Protein Kinase Cγ for Presynaptic Maintenance.

scientific article published on 22 November 2017

The Subcellular Dynamics of the Gs-Linked Receptor GPR3 Contribute to the Local Activation of PKA in Cerebellar Granular Neurons

scientific article

The Toll-like receptor 4-activated neuroprotective microglia subpopulation survives via granulocyte macrophage colony-stimulating factor and JAK2/STAT5 signaling.

scientific article published on 21 January 2016

Validation of Anti-CSPα, SNAP25, Tyrosine Hydroxylase, Ubiquitin, Cleaved Caspase 3, and pSer PKC Motif Antibodies for Utilization in Western Blotting

scientific article published on 21 December 2017