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List of works by Rona Giffard

Acidosis reduces neuronal apoptosis ⬇️

scientific article published on March 30, 1998

Advances in understanding protection from cerebral ischemia.

scientific article published on October 2002

Age-related defects in sensorimotor activity, spatial learning, and memory in C57BL/6 mice.

scientific article

Agmatine reduces infarct area in a mouse model of transient focal cerebral ischemia and protects cultured neurons from ischemia-like injury.

scientific article

Antegrade cerebral perfusion reduces apoptotic neuronal injury in a neonatal piglet model of cardiopulmonary bypass.

scientific article published in March 2006

Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.

scientific article

Astrocyte-enriched miR-29a targets PUMA and reduces neuronal vulnerability to forebrain ischemia

scientific article published on 30 August 2013

Ca2+-dependent binding of severin to actin: a one-to-one complex is formed.

scientific article

Ca2+-sensitive isolation of a cortical actin matrix from Dictyostelium amoebae

scientific article published on 01 February 1983

Caspase inhibitors reduce the apoptotic but not necrotic component of kainate injury in primary murine cortical neuronal cultures.

scientific article published in December 2002

Cell death in the central nervous system: therapeutic possibilities?

scientific article

Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury.

scientific article published in August 2004

Correlation of CGS 19755 neuroprotection against in vitro excitotoxicity and focal cerebral ischemia.

scientific article published in September 1995

Development of neonatal murine microglia in vitro: changes in response to lipopolysaccharide and ischemia-like injury.

scientific article

Direct protection of cultured neurons from ischemia-like injury by minocycline.

scientific article published on 31 December 2010

ER-Mitochondria Crosstalk during Cerebral Ischemia: Molecular Chaperones and ER-Mitochondrial Calcium Transfer ⬇️

scientific article published on 02 April 2012

Effect of Bcl-x(L) overexpression on reactive oxygen species, intracellular calcium, and mitochondrial membrane potential following injury in astrocytes.

scientific article published in August 2002

Effect of overexpression of protective genes on mitochondrial function of stressed astrocytes.

scientific article published in August 2004

Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse.

scientific article

Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways.

scientific article published on 7 March 2011

Extracellular alkalinity exacerbates injury of cultured cortical neurons

scientific article published on December 1, 1992

Geldanamycin reduces necrotic and apoptotic injury due to oxygen-glucose deprivation in astrocytes.

scientific article published in October 2003

Gene therapy and hypothermia for stroke treatment.

scientific article

Genomic analysis of reactive astrogliosis

scientific article published in May 2012

Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity

scientific article published in June 1995

Gpr124 is essential for blood-brain barrier integrity in central nervous system disease

scientific article published on 13 March 2017

Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice ⬇️

scientific article published on November 23, 2010

Heat shock protein 72 overexpression prevents early postoperative memory decline after orthopedic surgery under general anesthesia in mice

scientific article

Human Papilloma Virus Type 16 E7 Genes Protect Astrocytes against Apoptotic and Necrotic Death Induced by Hydrogen Peroxide ⬇️

scientific article published on October 1, 2001

IL-4 Is Required for Sex Differences in Vulnerability to Focal Ischemia in Mice.

scientific article published on 30 June 2015

Increased production of extracellular glutamate by the mitochondrial glutaminase following neuronal death.

scientific article

Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia.

scientific article published on 19 November 2008

Inflammation, mitochondria, and the inhibition of adult neurogenesis

scientific article

Influence of mild hypothermia on inducible nitric oxide synthase expression and reactive nitrogen production in experimental stroke and inflammation.

scientific article

Inhibition of miR-181a protects female mice from transient focal cerebral ischemia by targeting astrocyte estrogen receptor-α.

scientific article published on 15 May 2017

Inhibition of microRNA-181 reduces forebrain ischemia-induced neuronal loss

scientific article published on 04 September 2013

Inhibition of mitochondrial function in astrocytes: implications for neuroprotection.

scientific article published on August 2007

Ischemic vulnerability of primary murine microglial cultures.

scientific article

Many mechanisms for hsp70 protection from cerebral ischemia.

scientific article published on January 2004

Mechanism of heat shock protein 72 induction in primary cultured astrocytes after oxygen-glucose deprivation.

scientific article published on February 1996

MicroRNA Changes in Preconditioning-Induced Neuroprotection

scientific article

MicroRNA-320 induces neurite outgrowth by targeting ARPP-1 ⬇️

scientific article published on July 11, 2012

MicroRNAs regulate the chaperone network in cerebral ischemia

scientific article published on 17 August 2013

Microglia potentiate damage to blood-brain barrier constituents: improvement by minocycline in vivo and in vitro.

scientific article published on 23 February 2006

Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade.

scientific article

Mitochondrial protection attenuates inflammation-induced impairment of neurogenesis in vitro and in vivo.

scientific article

NOx and ADMA changes with focal ischemia, amelioration with the chaperonin GroEL.

scientific article

Neuronal calcium channels.

scientific article

Neuroprotection by the N-methyl-D-aspartate receptor antagonist CGP 40116: in vivo and in vitro studies

scientific article published on 01 August 1995

Neuroprotection from stroke in the absence of MHCI or PirB.

scientific article published on 21 March 2012

Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids.

scientific article published in October 1994

Neuroprotective effects of bcl-2 overexpression in hippocampal cultures: interactions with pathways of oxidative damage.

scientific article published in November 2002

Over-expression of HSP-70 protects astrocytes from combined oxygen-glucose deprivation.

scientific article published on January 1996

Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress.

scientific article published on November 2010

Overexpression of HDJ-2 protects astrocytes from ischemia-like injury and reduces redistribution of ubiquitin staining in vitro.

scientific article published in October 2003

Overexpression of HSP72 after Induction of Experimental Stroke Protects Neurons from Ischemic Damage ⬇️

scientific article published on November 1, 2001

Overexpression of bcl-2, bcl-XL or hsp70 in murine cortical astrocytes reduces injury of co-cultured neurons.

scientific article published in December 1999

Overexpression of bcl-xL protects astrocytes from glucose deprivation and is associated with higher glutathione, ferritin, and iron levels.

scientific article published on October 1999

Overexpression of copper/zinc superoxide dismutase decreases ischemia-like astrocyte injury.

scientific article

Overexpression of inducible heat shock protein 70 and its mutants in astrocytes is associated with maintenance of mitochondrial physiology during glucose deprivation stress.

scientific article

Overexpression of mitochondrial Hsp70/Hsp75 protects astrocytes against ischemic injury in vitro.

scientific article published on 19 December 2007

Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin

scientific article published on May 1, 1992

Perinatal Brain Injury: The Role of Development in Vulnerability ⬇️

scientific article published on May 1, 2003

Physiologically normal 5% O2 supports neuronal differentiation and resistance to inflammatory injury in neural stem cell cultures

scientific article published on 3 July 2015

Postischemic brain injury is attenuated in mice lacking the beta2-adrenergic receptor.

scientific article published on January 2009

Potentiation of murine astrocyte antioxidant defence by bcl‐2: protection in part reflects elevated glutathione levels ⬇️

scientific article published on April 1, 1998

Principles of gene therapy: potential applications in the treatment of cerebral ischaemia.

scientific article

Quantitative characterization and analysis of the dynamic NF-κB response in microglia ⬇️

scientific article published on July 5, 2011

Regulation of apoptotic and inflammatory cell signaling in cerebral ischemia: the complex roles of heat shock protein 70

scientific article published on August 2008

Regulation of the rat brain Na+ -driven Cl-/HCO3 - exchanger involves protein kinase A and a multiprotein signaling complex

scientific journal article

Role of Astrocytes in Delayed Neuronal Death: GLT-1 and its Novel Regulation by MicroRNAs.

scientific article published in January 2014

Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions.

scientific article

Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke.

scientific article

Stroke‐induced activation of the α7 nicotinic receptor increasesPseudomonas aeruginosalung injury ⬇️

scientific article published on April 9, 2012

Susceptibility to apoptosis varies with time in culture for murine neurons and astrocytes: changes in gene expression and activity.

scientific article published in September 2004

The 70 kDa heat shock protein suppresses matrix metalloproteinases in astrocytes.

scientific article published in March 2004

The electrogenic sodium bicarbonate cotransporter: developmental expression in rat brain and possible role in acid vulnerability.

scientific article published on February 2000

The future of molecular chaperones and beyond

scientific article published on August 2013

The neuroprotective potential of heat shock protein 70 (HSP70).

scientific article

Two tips for users of Bullard Intubating Laryngoscope.

scientific article published in November 1998

UV-vulnerability of human papilloma virus type-16 E7-expressing astrocytes is associated with mitochondrial membrane depolarization and caspase-3 activation.

scientific article published in October 2002

Ultrastructure of excitotoxic neuronal death in murine cortical culture

scientific article published on 01 December 1995

Vulnerability to glucose deprivation injury correlates with glutathione levels in astrocytes.

scientific article published in February 1997

miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes.

scientific article published on 17 September 2011

miR-29a differentially regulates cell survival in astrocytes from cornu ammonis 1 and dentate gyrus by targeting VDAC1.

scientific article published on 20 August 2016

microRNAs: innovative targets for cerebral ischemia and stroke.

scientific article published on January 2013

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