List of works - Antonio Giuseppe Maria Cossu

A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.

scientific article published on 30 March 2017

A new mutation of the CDH1 gene in a patient with an aggressive signet-ring cell carcinoma of the stomach.

scientific article published on 13 November 2017

AKT activation drives the nuclear localization of CSE1L and a pro-oncogenic transcriptional activation in ovarian cancer cells.

scientific article published on 13 August 2013

Activating PIK3CA mutations coexist with BRAF or NRAS mutations in a limited fraction of melanomas

scientific article

Analysis of candidate genes through a proteomics-based approach in primary cell lines from malignant melanomas and their metastases.

scientific article

Anaplastic large cell lymphoma of the breast arising around mammary implant capsule: an Italian report.

scientific article published on 26 April 2013

Angiosarcoma of the thyroid: a light, electron microscopic and histoimmunological study

scientific article published on 01 June 1988

Assessment of genetic instability in melanocytic skin lesions through microsatellite analysis of benign naevi, dysplastic naevi, and primary melanomas and their metastases

scientific article published in April 2003

Assessment of germline and somatic alterations in main candidate genes among patients with multiple primary melanoma.

scientific article published on 6 May 2014

BRAF Mutations and Dysregulation of the MAP Kinase Pathway Associated to Sinonasal Mucosal Melanomas

scientific article published on 01 October 2019

BRAF gene is somatically mutated but does not make a major contribution to malignant melanoma susceptibility: the Italian Melanoma Intergroup Study

scientific article

BRAF/NRAS mutation frequencies among primary tumors and metastases in patients with melanoma

scientific article published on 21 May 2012

BRCA1 and BRCA2 germline mutations in Sardinian breast cancer families and their implications for genetic counseling

scientific article published on 01 December 2002

Breast Nodular Fasciitis: A Comprehensive Review.

scientific article

Characterizing Metastatic HER2-Positive Gastric Cancer at the CDH1 Haplotype.

scientific article published on 23 December 2017

Chromosomal abnormalities and microsatellite instability in sporadic endometrial cancer

scientific article published on 01 September 2002

Classic follicular dendritic reticulum cell tumor of the lymph node developing in a patient with a previous inflammatory pseudotumor–like proliferation

scientific article published on 01 February 2005

Comparison of BRAF Mutation Screening Strategies in a Large Real-Life Series of Advanced Melanoma Patients

scientific article published on 30 July 2020

Definition of the role of chromosome 9p21 in sporadic melanoma through genetic analysis of primary tumours and their metastases. The Melanoma Cooperative Group.

scientific article published on December 2000

Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis.

scientific article published on 3 October 2017

Dermoscopy and confocal microscopy for metachronous multiple melanomas: morphological, clinical, and molecular correlations.

scientific article published on 27 November 2017

Discrepant alterations in main candidate genes among multiple primary melanomas

scientific article

Distribution and significance of 14-3-3sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue

scientific article published in March 2004

ERCC1 polymorphisms as prognostic markers in T4 breast cancer patients treated with platinum-based chemotherapy

scientific article

Effect of dabrafenib on melanoma cell lines harbouring the BRAF(V600D/R) mutations

scientific article

Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model.

scientific article published on 18 January 2018

Epidemiology and genetic susceptibility of malignant melanoma in North Sardinia, Italy

scientific article

Epidemiology of thyroid cancer in an area of epidemic thyroid goiter.

scientific article published on 4 March 2013

Expression of p34(cdc2) and cyclins A and B compared to other proliferative features of non-Hodgkin's lymphomas: a multivariate cluster analysis

scientific article published on 01 October 1999

Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer

scientific article published in May 2004

Factors predicting the occurrence of germline mutations in candidate genes among patients with cutaneous malignant melanoma from South Italy

scientific article published on 19 October 2006

Female Adnexal Tumors of Probable Wolffian Origin (FATWO): A Case Series With Next-Generation Sequencing Mutation Analysis.

scientific article

Genetic alterations in main candidate genes during melanoma progression.

scientific article published on 3 January 2018

Genetic instability and increased mutational load: which diagnostic tool best direct patients with cancer to immunotherapy?

scientific article published on 21 January 2017

Germline and somatic mutations in patients with multiple primary melanomas: a next generation sequencing study

scientific article published on 05 August 2019

Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma

scientific article published on 29 August 2013

High-resolution methylation analysis of the hMLH1 promoter in sporadic endometrial and colorectal carcinomas.

scientific article published on October 2003

Identification of predictive factors for the occurrence of predisposing MLH1 and MSH2 germline mutations among Sardinian patients with colorectal carcinoma.

scientific article published in May 2005

Induction of arginosuccinate synthetase (ASS) expression affects the antiproliferative activity of arginine deiminase (ADI) in melanoma cells.

scientific article published on 18 March 2011

Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans

scientific article published on 05 December 2016

KRAS mutational concordance between primary and metastatic colorectal adenocarcinoma.

scientific article

Long non-coding RNA CASC2 in human cancer

scientific article published on 12 January 2017

Low Levels of Genetic Heterogeneity in Matched Lymph Node Metastases from Patients with Melanoma.

scientific article

Lung cancer epidemiology in North Sardinia, Italy.

scientific article published on 12 July 2013

Microsatellite Instability in Endometrial Cancer: Relation to Histological Subtypes

scientific article published on 01 May 1999

Microsatellite instability and mutation analysis among southern Italian patients with colorectal carcinoma: detection of different alterations accounting for MLH1 and MSH2 inactivation in familial cases.

scientific article

Microsatellite instability and mutation analysis of candidate genes in unselected sardinian patients with endometrial carcinoma

article

Molecular Classification of Patients With Malignant Melanoma for New Therapeutic Strategies

Molecular Pathways in Melanomagenesis: What We Learned from Next-Generation Sequencing Approaches

scientific article published on 14 September 2018

Molecular alterations at chromosome 9p21 in melanocytic naevi and melanoma

scientific article published on 19 November 2007

Molecular analysis of Fanconi anemia and mismatch repair genes in patients with colorectal carcinoma

article

Multiple Molecular Pathways in Melanomagenesis: Characterization of Therapeutic Targets

scientific article (publication date: 2015)

Mutation analysis of candidate genes in melanoma-prone families

article

Mutational concordance between primary and metastatic melanoma: a next-generation sequencing approach

scientific article published on 28 August 2019

Mutations in ERBB4 may have a minor role in melanoma pathogenesis

scientific article published on 22 January 2013

Numerical abnormalities of chromosomes 1 and 10 in endometrial adenocarcinoma: fluorescence in situ hybridization analysis of 23 archival paraffin-embedded samples.

scientific article

Oral lichenoid eruption secondary to imatinib (Glivec).

scientific article

Origin and distribution of the BRCA2-8765delAG mutation in breast cancer

scientific article

Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.

scientific article published on 18 July 2017

Perivascular Epithelioid Cell Tumors (PEComas) of the Orbit.

scientific article published on 05 January 2017

Phase III randomized study of fotemustine and dacarbazine versus dacarbazine with or without interferon-α in advanced malignant melanoma

scientific article published on 13 February 2013

Phenotype characterization of human melanoma cells resistant to dabrafenib

scientific article

Presence of Jaagsiekte sheep retrovirus in tissue sections from human bronchioloalveolar carcinoma depends on patients' geographical origin

scientific article published on 01 February 2008

Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia.

scientific article

Primary dermal melanoma in a patient with a history of multiple malignancies: a case report with molecular characterization.

scientific article

Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study

scientific article published on 13 October 2016

Prognostic role of KRAS mutations in Sardinian patients with colorectal carcinoma

scientific article published on 29 June 2016

Prognostic value of circulating melanoma cells detected by reverse transcriptase-polymerase chain reaction

scientific article

Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis.

scientific article published in February 2004

Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy

scientific article

Serial detection of circulating tumour cells by reverse transcriptase-polymerase chain reaction assays is a marker for poor outcome in patients with malignant melanoma

scientific article

Sinonasal haemangiopericytoma: a case report

scientific article published on 09 January 2004

Spectrum and prevalence ofBRCA1 andBRCA2 germline mutations in Sardinian patients with breast carcinoma through hospital-based screening

article

The susceptibility CDKN2 locus may have a role on prognosis of melanoma patients

scientific article published on 15 March 2010

Triple-negative breast cancer frequency and type of BRCA mutation: Clues from Sardinia.

scientific article published on 28 January 2014

Unexpected distribution of cKIT and BRAF mutations among southern Italian patients with sinonasal melanoma

scientific article published on 29 June 2013

Vitamin D status and risk for malignant cutaneous melanoma: recent advances.

scientific article

X-inactivation patch size in human female tissue confounds the assessment of tumor clonality

scholarly article

List of works by Antonio Giuseppe Maria Cossu

A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.

A new mutation of the CDH1 gene in a patient with an aggressive signet-ring cell carcinoma of the stomach.

AKT activation drives the nuclear localization of CSE1L and a pro-oncogenic transcriptional activation in ovarian cancer cells.

Activating PIK3CA mutations coexist with BRAF or NRAS mutations in a limited fraction of melanomas

Analysis of candidate genes through a proteomics-based approach in primary cell lines from malignant melanomas and their metastases.

Anaplastic large cell lymphoma of the breast arising around mammary implant capsule: an Italian report.

Angiosarcoma of the thyroid: a light, electron microscopic and histoimmunological study

Assessment of genetic instability in melanocytic skin lesions through microsatellite analysis of benign naevi, dysplastic naevi, and primary melanomas and their metastases

Assessment of germline and somatic alterations in main candidate genes among patients with multiple primary melanoma.

BRAF Mutations and Dysregulation of the MAP Kinase Pathway Associated to Sinonasal Mucosal Melanomas

BRAF gene is somatically mutated but does not make a major contribution to malignant melanoma susceptibility: the Italian Melanoma Intergroup Study

BRAF/NRAS mutation frequencies among primary tumors and metastases in patients with melanoma

BRCA1 and BRCA2 germline mutations in Sardinian breast cancer families and their implications for genetic counseling

Breast Nodular Fasciitis: A Comprehensive Review.

Characterizing Metastatic HER2-Positive Gastric Cancer at the CDH1 Haplotype.

Chromosomal abnormalities and microsatellite instability in sporadic endometrial cancer

Classic follicular dendritic reticulum cell tumor of the lymph node developing in a patient with a previous inflammatory pseudotumor–like proliferation

Comparison of BRAF Mutation Screening Strategies in a Large Real-Life Series of Advanced Melanoma Patients

Definition of the role of chromosome 9p21 in sporadic melanoma through genetic analysis of primary tumours and their metastases. The Melanoma Cooperative Group.

Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis.

Dermoscopy and confocal microscopy for metachronous multiple melanomas: morphological, clinical, and molecular correlations.

Discrepant alterations in main candidate genes among multiple primary melanomas

Distribution and significance of 14-3-3sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue

ERCC1 polymorphisms as prognostic markers in T4 breast cancer patients treated with platinum-based chemotherapy

Effect of dabrafenib on melanoma cell lines harbouring the BRAF(V600D/R) mutations

Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model.

Epidemiology and genetic susceptibility of malignant melanoma in North Sardinia, Italy

Epidemiology of thyroid cancer in an area of epidemic thyroid goiter.

Expression of p34(cdc2) and cyclins A and B compared to other proliferative features of non-Hodgkin's lymphomas: a multivariate cluster analysis

Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer

Factors predicting the occurrence of germline mutations in candidate genes among patients with cutaneous malignant melanoma from South Italy

Female Adnexal Tumors of Probable Wolffian Origin (FATWO): A Case Series With Next-Generation Sequencing Mutation Analysis.

Genetic alterations in main candidate genes during melanoma progression.

Genetic instability and increased mutational load: which diagnostic tool best direct patients with cancer to immunotherapy?

Germline and somatic mutations in patients with multiple primary melanomas: a next generation sequencing study

Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma

High-resolution methylation analysis of the hMLH1 promoter in sporadic endometrial and colorectal carcinomas.

Identification of predictive factors for the occurrence of predisposing MLH1 and MSH2 germline mutations among Sardinian patients with colorectal carcinoma.

Induction of arginosuccinate synthetase (ASS) expression affects the antiproliferative activity of arginine deiminase (ADI) in melanoma cells.

Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans

KRAS mutational concordance between primary and metastatic colorectal adenocarcinoma.

Long non-coding RNA CASC2 in human cancer

Low Levels of Genetic Heterogeneity in Matched Lymph Node Metastases from Patients with Melanoma.

Lung cancer epidemiology in North Sardinia, Italy.

Microsatellite Instability in Endometrial Cancer: Relation to Histological Subtypes

Microsatellite instability and mutation analysis among southern Italian patients with colorectal carcinoma: detection of different alterations accounting for MLH1 and MSH2 inactivation in familial cases.

Microsatellite instability and mutation analysis of candidate genes in unselected sardinian patients with endometrial carcinoma

Molecular Classification of Patients With Malignant Melanoma for New Therapeutic Strategies

Molecular Pathways in Melanomagenesis: What We Learned from Next-Generation Sequencing Approaches

Molecular alterations at chromosome 9p21 in melanocytic naevi and melanoma

Molecular analysis of Fanconi anemia and mismatch repair genes in patients with colorectal carcinoma

Multiple Molecular Pathways in Melanomagenesis: Characterization of Therapeutic Targets

Mutation analysis of candidate genes in melanoma-prone families

Mutational concordance between primary and metastatic melanoma: a next-generation sequencing approach

Mutations in ERBB4 may have a minor role in melanoma pathogenesis

Numerical abnormalities of chromosomes 1 and 10 in endometrial adenocarcinoma: fluorescence in situ hybridization analysis of 23 archival paraffin-embedded samples.

Oral lichenoid eruption secondary to imatinib (Glivec).

Origin and distribution of the BRCA2-8765delAG mutation in breast cancer

Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.

Perivascular Epithelioid Cell Tumors (PEComas) of the Orbit.

Phase III randomized study of fotemustine and dacarbazine versus dacarbazine with or without interferon-α in advanced malignant melanoma

Phenotype characterization of human melanoma cells resistant to dabrafenib

Presence of Jaagsiekte sheep retrovirus in tissue sections from human bronchioloalveolar carcinoma depends on patients' geographical origin

Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia.

Primary dermal melanoma in a patient with a history of multiple malignancies: a case report with molecular characterization.

Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study

Prognostic role of KRAS mutations in Sardinian patients with colorectal carcinoma

Prognostic value of circulating melanoma cells detected by reverse transcriptase-polymerase chain reaction

Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis.

Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy

Serial detection of circulating tumour cells by reverse transcriptase-polymerase chain reaction assays is a marker for poor outcome in patients with malignant melanoma

Sinonasal haemangiopericytoma: a case report

Spectrum and prevalence ofBRCA1 andBRCA2 germline mutations in Sardinian patients with breast carcinoma through hospital-based screening

The susceptibility CDKN2 locus may have a role on prognosis of melanoma patients

Triple-negative breast cancer frequency and type of BRCA mutation: Clues from Sardinia.

Unexpected distribution of cKIT and BRAF mutations among southern Italian patients with sinonasal melanoma

Vitamin D status and risk for malignant cutaneous melanoma: recent advances.

X-inactivation patch size in human female tissue confounds the assessment of tumor clonality