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Authors whose works are in public domain in at least one jurisdiction

List of works by Juan Bolanos

A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.

scientific article published in April 2001

APC/CCdh1-Rock2 pathway controls dendritic integrity and memory

scientific article

Adapting glycolysis to cancer cell proliferation: the MAPK pathway focuses on PFKFB3

scientific article (publication date: 15 June 2013)

Age dependent changes in the cerebrospinal fluid concentration of nitrite and nitrate

scientific article published on 01 January 1996

Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization

scientific article published on 16 November 2018

Antioxidant and bioenergetic coupling between neurons and astrocytes.

scientific article published on April 2012

Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function.

scientific article

Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway.

scientific article

Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour

scientific article published on 04 February 2019

Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid.

scientific article published on 10 October 2009

Bioenergetics and redox adaptations of astrocytes to neuronal activity.

scientific article published on 10 March 2016

Brain energy metabolism in glutamate-receptor activation and excitotoxicity: role for APC/C-Cdh1 in the balance glycolysis/pentose phosphate pathway.

scientific article published on 12 February 2013

Cdh1/Hct1-APC is essential for the survival of postmitotic neurons.

scientific article published on September 2005

Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

scientific journal article

Cdk5-mediated inhibition of APC/C-Cdh1 switches on the cyclin D1-Cdk4-pRb pathway causing aberrant S-phase entry of postmitotic neurons.

scientific article

Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes.

scientific article published on 31 October 2016

Current technical approaches to brain energy metabolism

scientific article published on 7 November 2017

Cyclo(His-Pro) promotes cytoprotection by activating Nrf2-mediated up-regulation of antioxidant defence.

scientific article published on 29 March 2008

D-Glucose prevents glutathione oxidation and mitochondrial damage after glutamate receptor stimulation in rat cortical primary neurons

scientific article published on 01 October 2000

DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulating Pink1.

scientific article

Depletion of brain glutathione results in a decrease of glutathione reductase activity; an enzyme susceptible to oxidative damage.

scientific article

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury

scientific article

Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection.

scientific article

Does APC/CCDH1 control the human brain size?: An Editorial Highlight for 'A novel human Cdh1 mutation impairs anaphase-promoting complex/cyclosome (APC/C) activity resulting in microcephaly, psychomotor retardation, and epilepsy' on page 103

scientific article published on 23 August 2019

E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation

scientific article

Effect of hypoxia on urea synthesis in neonatal rat liver in vitro

scientific article published on 01 December 1990

Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture

scientific article published on 01 May 1995

Effect of valproate on lipogenesis in neonatal rat brain.

scientific article published in March 1993

Effect of valproate on the metabolism of the central nervous system.

scientific article published on January 1997

Erratum to: Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway.

scientific article published on 16 February 2017

Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells

scientific article published on 01 November 2019

Evaluation of the efficacy of potential therapeutic agents at protecting against nitric oxide synthase-mediated mitochondrial damage in activated astrocytes

scientific article published on August 1, 1997

Expression of glucose transporter GLUT3 by endotoxin in cultured rat astrocytes: the role of nitric oxide.

scientific article

Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity

scientific article published on 17 September 2020

Glucose metabolism links astroglial mitochondria to cannabinoid effects

scientific article published on 08 July 2020

Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion.

scientific article published in April 1998

Glutathione and γ-Glutamylcysteine in Hydrogen Peroxide Detoxification

scientific article published on January 1, 2013

Glutathione and γ-glutamylcysteine in the antioxidant and survival functions of mitochondria.

scientific article published on February 2013

Glutathione depletion is accompanied by increased neuronal nitric oxide synthase activity

scientific article published on 01 January 1996

Glutathione protects astrocytes from peroxynitrite-mediated mitochondrial damage: implications for neuronal/astrocytic trafficking and neurodegeneration

scientific article published on 01 January 1996

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

scientific article

Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function

scientific article published on 07 August 2018

Increased mitochondrial respiration maintains the mitochondrial membrane potential and promotes survival of cerebellar neurons in an endogenous model of glutamate receptor activation.

scientific article published in January 2005

Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway

scientific article published on June 2016

Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway

scientific journal article

Inhibition of astrocyte gap junctional communication by ATP depletion is reversed by calcium sequestration

scientific article published on 01 September 1996

Inhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5'-AMP-activated protein kinase

scientific journal article

Inhibition of neonatal brain fuel utilization by valproate and E-delta 2-valproate is not a consequence of the stimulation of the gamma-aminobutyric acid shunt.

scientific article published in January 1994

Integrating Molecular Mechanisms with Synaptic Plasticity in Neurological Disease

scientific article published on August 26, 2012

Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system.

scientific article published on July 1997

Involvement of reactive oxygen species on gentamicin-induced mesangial cell activation.

scientific article published in November 2002

LRRK2 Expression Is Deregulated in Fibroblasts and Neurons from Parkinson Patients with Mutations in PINK1.

scientific article

Lactate utilization by neonatal rat liver in vitro

scientific article published on 01 December 1990

Linking glycolysis with oxidative stress in neural cells: a regulatory role for nitric oxide.

scientific article published on November 2007

Lipogenesis from lactate in fetal rat brain during late gestation.

scientific article published in January 1993

Melatonin induces the expression of Nrf2-regulated antioxidant enzymes via PKC and Ca2+ influx activation in mouse pancreatic acinar cells.

scientific article published on 7 July 2015

Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications.

scientific article published on 27 August 2009

Mitochondrial Complex I Activity is Conditioned by Supercomplex I-III2-IV Assembly in Brain Cells: Relevance for Parkinson's Disease.

scientific article

Mitochondrial control of cell bioenergetics in Parkinson's disease.

scientific article published on 15 April 2016

Mitochondrial damage: an important feature in a number of inborn errors of metabolism?

scientific article published on 01 January 1996

Mitochondrial respiratory chain and free radical generation in stroke.

scientific article

Mitochondrial respiratory chain disorganization in Parkinson's disease-relevant PINK1 and DJ1 mutants

scientific article

Modulation of astroglial energy metabolism by nitric oxide.

scientific article published on May 2006

NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program.

scientific article published on 17 April 2018

NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming.

scientific article published on 16 February 2016

Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism

scientific article published on 21 October 2016

Nitric oxide mediates brain mitochondrial damage during perinatal anoxia.

scientific article published in March 1998

Nitric oxide mediates brain mitochondrial maturation immediately after birth.

scientific article

Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration

scientific article published on 01 July 1995

Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.

scientific article

Nitric oxide, cell bioenergetics and neurodegeneration.

scientific article published on June 2006

Nitric oxide, energy metabolism and neurological disease.

scientific article published on August 1997

Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione

scientific article published on 01 January 1996

Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke

scientific article published on 07 October 2020

PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1.

scientific article published on 24 July 2014

Peroxiredoxin 5 links mitochondrial redox signalling with calcium dynamics: impact on Parkinson's disease

scientific article published on 27 February 2013

Peroxynitrite anion stimulates arginine release from cultured rat astrocytes

scientific article published on 01 October 1999

Peroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotection

scientific journal article

Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress

scientific journal article

Potential mechanisms for nitric oxide-mediated impairment of brain mitochondrial energy metabolism.

scientific article published on August 1997

Provoking neuroprotection by peroxynitrite.

scientific article published on January 2004

Redox status and bioenergetics liaison in cancer and neurodegeneration.

scientific article published on 11 September 2012

Regulation of BDNF Release by ARMS/Kidins220 through Modulation of Synaptotagmin-IV Levels

scientific article published on 16 May 2018

Regulation of Bcl-xL-ATP Synthase Interaction by Mitochondrial Cyclin B1-Cyclin-Dependent Kinase-1 Determines Neuronal Survival

scientific article

Regulation of glucose metabolism by nitrosative stress in neural cells.

scientific article published on February 2004

Single-Nucleotide Polymorphism 309T>G in the MDM2 Promoter Determines Functional Outcome After Stroke

scientific article published on 01 October 2018

TIGAR's promiscuity

scientific article published on 01 March 2014

Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice

scientific article published on 12 August 2019

The assumption that nitric oxide inhibits mitochondrial ATP synthesis is correct.

scientific article published in March 1999

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

scientific article published on 17 May 2009

The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke.

scientific article

The oxidized form of vitamin C, dehydroascorbic acid, regulates neuronal energy metabolism

scientific article published on 19 February 2014

The pentose-phosphate pathway in neuronal survival against nitrosative stress.

scientific article published on January 2010

Trolox protects mitochondrial complex IV from nitric oxide-mediated damage in astrocytes

scientific article published on 01 December 1994

Uncertainties in pentose-phosphate pathway flux assessment underestimate its contribution to neuronal glucose consumption: relevance for neurodegeneration and aging

scientific article

Underestimation of the pentose-phosphate pathway in intact primary neurons as revealed by metabolic flux analysis.

scientific article published on 25 September 2013

p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1

scientific article published on 10 November 2021

α-Ketoglutarate dehydrogenase complex moonlighting: ROS signalling added to the list: An Editorial highlight for 'Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?'

scientific article published in December 2016