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List of works by Nikolai G. Rainov

A dual function fusion protein of Herpes simplex virus type 1 thymidine kinase and firefly luciferase for noninvasive in vivo imaging of gene therapy in malignant glioma

scientific article

A neuroblastoma-selective suicide gene therapy approach using the tyrosine hydroxylase promoter.

scientific article published on 4 June 2004

A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

scientific article published in November 2000

Abdominal CSF pseudocysts in patients with ventriculo-peritoneal shunts. Report of fourteen cases and review of the literature.

scientific article published in January 1994

Absence of p53 autoantibodies in sera from glioma patients.

scientific article

Alginate encapsulation of genetically engineered mammalian cells: comparison of production devices, methods and microcapsule characteristics.

scientific article published in May 2003

Anterior cervical fusion with the Orion locking plate system

scientific article published on 01 August 1998

Atrial placement of ventriculoatrial shunts

scientific article published on 01 March 1997

Autoantibodies to the inhibitor of apoptosis protein survivin in patients with brain tumors.

scientific article published in January 2007

Back to the roots of modern neurosurgery: neurosurgical pioneers in Halle an der Saale.

scientific article

Bioluminescence imaging in vivo – application to cancer research ⬇️

scientific article published on October 1, 2003

Cerebellar liponeurocytoma with an unusually aggressive clinical course: case report.

scientific article

Cerebral amyloid angiopathy with symptomatic or occult subarachnoid haemorrhage

scientific article published on 15 December 2006

Cerebroventricular infusion of pentosan polysulphate in human variant Creutzfeldt-Jakob disease.

scientific article published in June 2005

Clinical development of experimental therapies for malignant glioma.

scientific article

Clinical development of experimental virus-mediated gene therapy for malignant glioma.

scientific article published on October 2011

Clinical trials with intracerebral convection-enhanced delivery of targeted toxins in malignant glioma.

scientific article published on January 2008

Co-expression of Fas and Fas ligand in malignant glial tumors and cell lines ⬇️

scientific article published on March 1, 1998

Combined effects of temozolomide and the ribonucleotide reductase inhibitors didox and trimidox in malignant brain tumor cells.

scientific article published on 11 April 2003

Combined radiation and cytochrome CYP4B1/4-ipomeanol gene therapy using the EGR1 promoter.

scientific article published in May 2003

Complete disappearance of giant intracranial germinoma after irradiation

scientific article published on 01 January 1995

Continuous monitoring of the partial pressure of oxygen in cerebral venous blood.

scientific article published in August 1997

Coronally oriented vertical fracture of the axis body: surgical treatment of a rare condition

scientific article published on 01 June 1998

Differential effect of imatinib and synergism of combination treatment with chemotherapeutic agents in malignant glioma cells.

scientific article

Direct anterior fixation of odontoid fractures with a hollow spreading screw system

scientific article published on 01 January 1996

Dorsal spondylodesis of unstable thoracolumbar fractures by a far-lateral approach to the disc.

scientific article published in December 1997

Dual electrode spinal cord stimulation in chronic leg and back pain.

scientific article published on January 2007

Epidural electrical stimulation of the motor cortex in patients with facial neuralgia ⬇️

scientific article published on August 1, 1997

Experimental strategies for combined suicide and immune cancer gene therapy. An overview.

scientific article

Expression of mutant non-cleavable Fas ligand on retrovirus packaging cells causes apoptosis of immunocompetent cells and improves prodrug activation gene therapy in a malignant glioma model.

scientific article published in August 2003

Expression of survivin, platelet-derived growth factor A (PDGF-A) and PDGF receptor alpha in primary central nervous system lymphoma.

scientific article published on 19 July 2006

Factors predicting pituitary adenoma invasiveness in acromegalic patients ⬇️

scientific article published on January 1, 1997

Gamma-glutamyl transferase expression in higher-grade astrocytic glioma.

scientific article

Gene therapy for brain tumors

scientific article published on 01 October 1995

Gene therapy for human malignant brain tumors.

scientific article

Green fluorescent protein as a reporter for retrovirus and helper virus-free HSV-1 amplicon vector-mediated gene transfer into neural cells in culture and in vivo.

scientific article published in December 1997

Hardware failures in spinal cord stimulation (SCS) for chronic benign pain of spinal origin.

scientific article published on January 2007

Hardware failures in spinal cord stimulation for failed back surgery syndrome

scientific article published on 01 January 2000

Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors.

scientific article published in February 1996

High throughput encapsulation of murine fibroblasts in alginate using the JetCutter technology

scientific article published in May 2002

Hot topics issue: immunotherapy of cancer

scientific article published on 01 January 2008

Hypoxia-inducible transgene expression in differentiated human NT2N neurons--a cell culture model for gene therapy of postischemic neuronal loss.

scientific article

Identification of genotoxic stress in human cells by fluorescent monitoring of p53 expression.

scientific article

Immune response induced by retrovirus-mediated HSV-tk/GCV pharmacogene therapy in patients with glioblastoma multiforme.

scientific article published in November 2000

Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene--a phase I/II clinical protocol.

scientific article published in August 2003

Increased expression of ABCB6 enhances protoporphyrin IX accumulation and photodynamic effect in human glioma.

scientific article published on 12 June 2012

Infection rates of external ventricular drains are reduced by the use of silver-impregnated catheters

scientific article published on 27 February 2013

Intervertebral disc replacement for cervical degenerative disease--clinical results and functional outcome at two years in patients implanted with the Bryan cervical disc prosthesis

scientific article published on 20 April 2008

Intracellular localization of Herpes simplex virus type 1 thymidine kinase fused to different fluorescent proteins depends on choice of fluorescent tag.

scientific article

Intravascular delivery of neural stem cell lines to target intracranial and extracranial tumors of neural and non-neural origin.

scientific article

Liposome-mediated transfer of the bcl-2 gene results in neuroprotection after in vivo transient focal cerebral ischemia in an animal model.

scientific article

Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma ⬇️

scientific article published on January 1, 2003

Long-term intrathecal infusion of drug combinations for chronic back and leg pain.

scientific article

Long-term survival in a rodent brain tumor model by bradykinin-enhanced intra-arterial delivery of a therapeutic herpes simplex virus vector

scientific article published on May 1, 1998

Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment.

scientific article published in October 1996

Making a case for programmable pumps over fixed rate pumps for the management of fluctuations in chronic pain and spasticity: a literature review.

scientific article published on April 2002

Malignant growth of a recurrent macroprolactinoma after radiation therapy

scientific article published on 01 September 1993

Management of chronic back and leg pain by intrathecal drug delivery.

scientific article published on January 2007

MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status.

scientific article published on 9 June 2011

Miliary Metastatic Tumors ⬇️

scientific article published on December 1, 1997

Miliary brain metastases from malignant melanoma

scientific article published on 01 January 1996

Motor cortex stimulation for neuropathic facial pain.

scientific article

Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas

scientific article published in November 2000

New Prodrug Activation Gene Therapy for Cancer Using Cytochrome P450 4B1 and 2-Aminoanthracene/4-Ipomeanol ⬇️

scientific article published on June 10, 1998

Nontraumatic spinal epidural hematoma associated with clopidogrel.

scientific article published on 14 November 2006

NovoTTF-100A versus physician's choice chemotherapy in recurrent glioblastoma: a randomised phase III trial of a novel treatment modality.

scientific article published on 18 May 2012

Occipito-cervical fusion with the cervical Cotrel-Dubousset rod system

scientific article published on 01 January 1998

Oncolytic viruses for treatment of malignant brain tumours.

scientific article published on January 2003

Outcome in Cloward anterior fusion for degenerative cervical spinal disease

scientific article published on 01 January 2000

Overall survival in patients with malignant glioma may be significantly longer with tumors located in deep grey matter.

scientific article published on May 2007

Patient-controlled Analgesia in Intrathecal Therapy for Chronic Pain: Safety and Effective Operation of the Model 8831 Personal Therapy Manager with a Pre-implanted SynchroMed Infusion System ⬇️

scientific article published on July 1, 2003

Pentosan polysulfate as a prophylactic and therapeutic agent against prion disease.

scientific article

Predisposing conditions and risk factors for development of symptomatic meningioma in adults

scientific article published on 26 September 2005

Prognostic factors in malignant glioma: influence of the overexpression of oncogene and tumor-suppressor gene products on survival

scientific article published on October 1, 1997

Quantitation of HSV mass distribution in a rodent brain tumor model.

scientific article published in October 2000

Rabbit cytochrome P450 4B1: A novel prodrug activating gene for pharmacogene therapy of hepatocellular carcinoma.

scientific article published on July 2000

Receptor tyrosine kinases as therapeutic targets in malignant glioma.

scientific article published on May 2007

Results and outcome of neurosurgical treatment for extradural metastases in the cervical spine

scientific article published on 01 October 2003

Reviews on Recent Clinical Trials. Tyrosine kinases.

scientific article published in May 2007

Rosette-forming glioneuronal tumor of the fourth ventricle

scientific article published on 31 March 2010

Selective delivery of herpes virus vectors to experimental brain tumors using RMP-7.

scientific article published in January 1999

Selective inhibition of PDGFR by imatinib elicits the sustained activation of ERK and downstream receptor signaling in malignant glioma cells.

scientific article published on 6 December 2010

Self-inflicted penetrating head injury in a patient with manic-depressive disorder.

scientific article published in June 2005

Somatostatin receptor scintigraphy in patients with pituitary adenoma

scientific article published on 01 January 1997

Spontaneous shrinking of a macroprolactinoma

scientific article published on 01 January 1993

Stathmin expression in glioma-derived microvascular endothelial cells: a novel therapeutic target.

scientific article published on 31 October 2011

Systemic activation of the immune system during ganciclovir treatment following intratumoral herpes simplex virus type 1 thymidine kinase gene transfer in an adolescent ependymoma patient.

scientific article

Targeted biological therapies for pain.

scientific article published on June 2011

Targeting gene therapy vectors to CNS malignancies.

scientific article

Technology evaluation: TransMID, KS Biomedix/Nycomed/Sosei/PharmaEngine.

scientific article

Technology evaluation: cintredekin besudotox, NeoPharm/Nippon.

scientific article

Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma.

scientific article

The egr-1 gene is induced by DNA-damaging agents and non-genotoxic drugs in both normal and neoplastic human cells.

scientific article published on May 2003

Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy.

scientific article published in November 1997

Thoracic and lumbar meningocele in neurofibromatosis type 1. Report of two cases and review of the literature.

scientific article published on January 1995

Thromboembolic complications in neurosurgical patients

scientific article

Transcranial Doppler sonography in adult hydrocephalic patients.

scientific article

Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects.

scientific article published in June 2000

Urokinase infusion for severe intraventricular haemorrhage

scientific article published on 01 January 1995

[Clinical laboratory research on the properties of Aquafresh toothpaste]

scientific article published on 01 January 1996

[Clinico-laboratory studies of the properties of Aquafresh toothpaste]

scientific article published on 01 January 1998

[Long-term results of surgical treatment of lumbar stenoses]

scientific article published on 01 January 1990

[The prospects for the use of fluoroquinolone preparations in the combined treatment of chronic generalized periodontitis at a stage of exacerbation]

scientific article published on 01 January 1998

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