List of works by Axel A Brakhage

A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity.

scientific article

A basic-region helix-loop-helix protein-encoding gene (devR) involved in the development of Aspergillus nidulans

scientific article published in April 2004

A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis

scientific article published on 22 July 2011

A new approach to drug discovery: high-throughput screening of microbial natural extracts against Aspergillus fumigatus using resazurin

scientific article

A single subunit of a heterotrimeric CCAAT-binding complex carries a nuclear localization signal: piggy back transport of the pre-assembled complex to the nucleus.

scientific article published in September 2004

Activation of a silent fungal polyketide biosynthesis pathway through regulatory cross talk with a cryptic nonribosomal peptide synthetase gene cluster

scientific article published on 15 October 2010

Activation of fungal silent gene clusters: a new avenue to drug discovery.

scientific article published on January 2008

Ahr1 and Tup1 Contribute to the Transcriptional Control of Virulence-Associated Genes in Candida albicans

scientific article published on 28 April 2020

Amphiphilic star-shaped block copolymers as unimolecular drug delivery systems: investigations using a novel fungicide

article published in 2013

An Efficient Method To Generate Gene Deletion Mutants of the Rapamycin-Producing Bacterium Streptomyces iranensis HM 35

scientific article

An Iterative O-Methyltransferase Catalyzes 1,11-Dimethylation of Aspergillus fumigatus Fumaric Acid Amides.

scientific article published on 21 July 2016

Analysis of mating-dependent transcription of Blakeslea trispora carotenoid biosynthesis genes carB and carRA by quantitative real-time PCR.

scientific article published on 3 March 2005

Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia

scientific article

Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development.

scientific article

Antigen-reactive T cell enrichment for direct, high-resolution analysis of the human naive and memory Th cell repertoire

scientific article published on 11 March 2013

Apoptosis inhibition of alveolar macrophages upon interaction with conidia of Aspergillus fumigatus

scientific article published on 22 August 2007

Arabidopsis thaliana responds to colonisation of Piriformospora indica by secretion of symbiosis-specific proteins

scientific article published in PLoS ONE

Aspects on evolution of fungal beta-lactam biosynthesis gene clusters and recruitment of trans-acting factors.

scientific article published on 26 October 2009

Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity

scientific article

Aspergillus fumigatus does not require fatty acid metabolism via isocitrate lyase for development of invasive aspergillosis

scientific article published on 18 December 2006

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence.

scientific article published on January 2012

Aspergillus fumigatus protein phosphatase PpzA is involved in iron assimilation, secondary metabolite production, and virulence

scientific article

Aspf2 From Recruits Human Immune Regulators for Immune Evasion and Cell Damage

Automated image analysis of the host-pathogen interaction between phagocytes and Aspergillus fumigatus

scientific article

Automated quantification of the phagocytosis of Aspergillus fumigatus conidia by a novel image analysis algorithm

scientific article published on 9 June 2015

Bacillus subtilis attachment to Aspergillus niger hyphae results in mutually altered metabolism

scientific article

Bacteria induce pigment formation in the basidiomycete Serpula lacrymans

scientific article

Bacteria-induced natural product formation in the fungus Aspergillus nidulans requires Saga/Ada-mediated histone acetylation

scientific article

Bacterium Induces Cryptic Meroterpenoid Pathway in the Pathogenic FungusAspergillus fumigatus

scientific article published in 2013

Bacterium induces cryptic meroterpenoid pathway in the pathogenic fungus Aspergillus fumigatus

scientific article published in 2013

Biosynthesis and function of gliotoxin in Aspergillus fumigatus

scientific article

Biotinylated Surfome Profiling Identifies Potential Biomarkers for Diagnosis and Therapy of Aspergillus fumigatus Infection

scientific article published on 12 August 2020

Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis

scientific article published on 30 May 2018

Carbon Catabolite Repression in Filamentous Fungi Is Regulated by Phosphorylation of the Transcription Factor CreA

scientific article published on 05 January 2021

Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus

scientific article published on 19 September 2006

Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence

scientific article

Chromatin mapping identifies BasR, a key regulator of bacteria-triggered production of fungal secondary metabolites

scientific article published on 12 October 2018

Clinical-scale isolation of the total Aspergillus fumigatus-reactive T-helper cell repertoire for adoptive transfer

scientific article published on 15 July 2015

Comparative Genome Analysis of Trichophyton rubrum and Related Dermatophytes Reveals Candidate Genes Involved in Infection

scientific article

Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi

scientific article

Comparative genomics of MAP kinase and calcium-calcineurin signalling components in plant and human pathogenic fungi.

scientific article published on 07 February 2009

Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus.

scientific article

Comparative proteomics of a tor inducible Aspergillus fumigatus mutant reveals involvement of the Tor kinase in iron regulation.

scientific article published on 26 May 2015

Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression

scientific article

Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway

scientific article published on 3 May 2011

Conidial surface proteins at the interface of fungal infections

scientific article published on 12 September 2019

Contribution of peroxisomes to penicillin biosynthesis in Aspergillus nidulans

scientific article published on 16 January 2009

Correction: Deletion of the α-(1,3)-Glucan Synthase Genes Induces a Restructuring of the Conidial Cell Wall Responsible for the Avirulence of Aspergillus fumigatus.

scientific article published on 22 November 2013

Correction: Gene Expansion Shapes Genome Architecture in the Human Pathogen Lichtheimia corymbifera: An Evolutionary Genomics Analysis in the Ancient Terrestrial Mucorales (Mucoromycotina).

scientific article published on 5 December 2016

Correction: Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

scientific article published on 14 December 2016

Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper.

scientific article published on 31 August 2016

Cytotoxic and antifungal activities of melleolide antibiotics follow dissimilar structure-activity relationships

scientific article published on 3 June 2014

Cytotoxic pheofungins from an engineered fungus impaired in posttranslational protein modification

scientific article published on 12 September 2011

DNA minor groove sensing and widening by the CCAAT-binding complex

scientific article

Deciphering the Counterplay of Aspergillus fumigatus Infection and Host Inflammation by Evolutionary Games on Graphs

scientific article published on 13 June 2016

Deciphering the combinatorial DNA-binding code of the CCAAT-binding complex and the iron-regulatory basic region leucine zipper (bZIP) transcription factor HapX.

scientific article published on 14 January 2015

Deletion of the Aspergillus fumigatus lysine biosynthesis gene lysF encoding homoaconitase leads to attenuated virulence in a low-dose mouse infection model of invasive aspergillosis

scientific article published on 30 March 2004

Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model

scientific article published on 31 August 2006

Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus

scientific article

Differential expression of silent polyketide biosynthesis gene clusters in chemostat cultures of Aspergillus nidulans

scientific article published on 26 January 2012

Direct Binding of the pH-Regulated Protein 1 (Pra1) from Candida albicans Inhibits Cytokine Secretion by Mouse CD4+ T Cells

scientific article published on 11 May 2017

Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus

scientific article

Distinct amino acids of histone H3 control secondary metabolism in Aspergillus nidulans

scientific article

Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus Verticillium hemipterigenum

scientific article published on 22 January 2015

Draft Genome Sequence of Streptomyces iranensis.

scientific article published on 17 July 2014

Draft Genome Sequence of the Fungus Penicillium brasilianum MG11

scientific article published on 3 September 2015

Draft Genome Sequences of Fungus Aspergillus calidoustus

scientific article

Dynamic Surface Proteomes of Allergenic Fungal Conidia

scientific article published on 31 March 2020

Dynamic optimization reveals alveolar epithelial cells as key mediators of host defense in invasive aspergillosis

scientific article published on 13 December 2021

Engineering fungal secondary metabolism: a roadmap to novel compounds

scientific article published on 20 July 2012

Enolase From Aspergillus fumigatus Is a Moonlighting Protein That Binds the Human Plasma Complement Proteins Factor H, FHL-1, C4BP, and Plasminogen

scientific article published on 22 November 2019

Environmental dimensionality controls the interaction of phagocytes with the pathogenic fungi Aspergillus fumigatus and Candida albicans

scientific article (publication date: February 2007)

Epidithiodiketopiperazine biosynthesis: a four-enzyme cascade converts glutathione conjugates into transannular disulfide bridges

scientific article published on 26 August 2013

Epidithiol formation by an unprecedented twin carbon-sulfur lyase in the gliotoxin pathway

scientific article

Erratum: Surface hydrophobin prevents immune recognition of airborne fungal spores

scientific article published in Nature

Evolution of beta-lactam biosynthesis genes and recruitment of trans-acting factors

scientific article

Extremophile Metal Resistance: Plasmid-Encoded Functions in Streptomyces mirabilis

scientific article published on 23 May 2022

Extrinsic extracellular DNA leads to biofilm formation and colocalizes with matrix polysaccharides in the human pathogenic fungus Aspergillus fumigatus

scientific article

Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi

scientific article published on 26 May 2018

Fast and Quantitative Evaluation of Human Leukocyte Interaction with Aspergillus fumigatus Conidia by Flow Cytometry

scientific article published on 19 November 2018

Flavoenzyme-catalyzed formation of disulfide bonds in natural products

scientific article

Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections

scientific article published on 01 August 2020

Functional Reconstitution of a Fungal Natural Product Gene Cluster by Advanced Genome Editing.

scientific article published on 9 September 2016

Functional characterization of the Aspergillus fumigatus calcineurin

scientific article published on 20 September 2006

Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin

scientific article published on September 2010

Functional surface proteomic profiling reveals the host heat-shock protein A8 as a mediator of Lichtheimia corymbifera recognition by murine alveolar macrophages

scientific article published on 24 June 2020

Fungal iron homeostasis with a focus on Aspergillus fumigatus

scientific article published on 09 October 2020

Fungal model systems and the elucidation of pathogenicity determinants

scientific article published on 07 July 2014

Fungal secondary metabolites - strategies to activate silent gene clusters

scientific article published on 28 April 2010

FungiFun: A web-based application for functional categorization of fungal genes and proteins

scientific article published on November 10, 2010

Fungus-specific CD4(+) T cells for rapid identification of invasive pulmonary mold infection.

scientific article

Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial mucorales (Mucoromycotina)

scientific article

Generation of an arginine-tRNA-adapted Saccharomyces cerevisiae strain for effective heterologous protein expression

scientific article published on 2 November 2017

Genetic engineering activates biosynthesis of aromatic fumaric acid amides in the human pathogen Aspergillus fumigatus

scientific article published on 19 December 2014

Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans

scientific article published on 18 March 2007

Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ.

scientific article published on 19 May 2017

Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase

scientific article published on 07 February 2019

Gliotoxin--bane or boon?

scientific article published on 07 October 2015

HapX Mediates Iron Homeostasis in the Pathogenic Dermatophyte Arthroderma benhamiae but Is Dispensable for Virulence

scientific article

HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus

scientific article

Heptahelical receptors GprC and GprD of Aspergillus fumigatus Are essential regulators of colony growth, hyphal morphogenesis, and virulence

scientific article

High-Throughput Gene Replacement in Aspergillus fumigatus

scientific article published on 01 September 2019

Hitting the caspofungin salvage pathway of human-pathogenic fungi with the novel lasso peptide humidimycin (MDN-0010).

scientific article published on 8 June 2015

Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans

scientific article published on 21 February 2019

Human Neutrophils Produce Antifungal Extracellular Vesicles against Aspergillus fumigatus

scientific article published on 14 April 2020

Human and plant fungal pathogens: the role of secondary metabolites

scientific article published on 30 January 2014

Hyperspectral Imaging Using Intracellular Spies: Quantitative Real-Time Measurement of Intracellular Parameters In Vivo during Interaction of the Pathogenic Fungus Aspergillus fumigatus with Human Monocytes

scientific article

Identification and Characterization of a Novel Aspergillus fumigatus Rhomboid Family Putative Protease, RbdA, Involved in Hypoxia Sensing and Virulence.

scientific article

Identification of dermatophyte species causing onychomycosis and tinea pedis by MALDI-TOF mass spectrometry

scientific article

Identification of hypoxia-inducible target genes of Aspergillus fumigatus by transcriptome analysis reveals cellular respiration as an important contributor to hypoxic survival

scientific article

Identification of immunogenic antigens from Aspergillus fumigatus by direct multiparameter characterization of specific conventional and regulatory CD4+ T cells

scientific article published on 29 August 2014

Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus.

scientific article published on 18 August 2015

Identification of the novel penicillin biosynthesis gene aatB of Aspergillus nidulans and its putative evolutionary relationship to this fungal secondary metabolism gene cluster

scientific article published in October 2008

Identification of virulence determinants of the human pathogenic fungi Aspergillus fumigatus and Candida albicans by proteomics

scientific article published on 12 May 2011

Immunoproteomic Analysis of Antibody Responses to Extracellular Proteins of Candida albicans Revealing the Importance of Glycosylation for Antigen Recognition

scientific article published on 8 July 2016

Immunoproteomics of Aspergillus for the development of biomarkers and immunotherapies

scientific article published on 17 June 2016

Impact of the cross-pathway control on the regulation of lysine and penicillin biosynthesis in Aspergillus nidulans.

scientific article published on 3 December 2002

Induction of Mitochondrial Reactive Oxygen Species Production by Itraconazole, Terbinafine, and Amphotericin B as a Mode of Action against Aspergillus fumigatus

scientific article

Integrative analysis of the heat shock response in Aspergillus fumigatus

scientific article

Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron

scientific article published on 14 June 2007

Interaction of phagocytes with filamentous fungi

scientific article published on 02 June 2010

Interference of Aspergillus fumigatus with the immune response

scientific article

Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans

scholarly article

Investigation of Aspergillus fumigatus biofilm formation by various "omics" approaches.

scientific article published on 12 February 2013

Lichen-like association of Chlamydomonas reinhardtii and Aspergillus nidulans protects algal cells from bacteria

scientific article published on 04 August 2020

Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9.

scientific article

Melanin dependent survival of Apergillus fumigatus conidia in lung epithelial cells

scientific article published on 26 April 2014

Melanin targets LC3-associated phagocytosis (LAP): A novel pathogenetic mechanism in fungal disease

scientific article

Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability.

scientific article published on 14 April 2010

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

scientific article published on 14 June 2018

Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis.

scientific article published on January 2008

Methylcitrate synthase from Aspergillus fumigatus. Propionyl-CoA affects polyketide synthesis, growth and morphology of conidia.

scientific article published on July 2005

Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters.

scientific article published on 20 April 2015

Microbial interactions trigger the production of antibiotics.

scientific article published on 24 April 2018

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Missing values in gel-based proteomics

scientific article

Mitogen activated protein kinases SakA(HOG1) and MpkC collaborate for Aspergillus fumigatus virulence.

scientific article

Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus

scientific article published on 26 March 2019

Molecular characterization of the Aspergillus fumigatus NCS-1 homologue, NcsA.

scientific article

Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages.

scientific article

N-Heterocyclization in Gliotoxin Biosynthesis is Catalyzed by a Distinct Cytochrome P450 Monooxygenase

scientific article published on 24 August 2020

Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus

scientific article

Novel basic-region helix-loop-helix transcription factor (AnBH1) of Aspergillus nidulans counteracts the CCAAT-binding complex AnCF in the promoter of a penicillin biosynthesis gene

scientific article published in October 2002

Nuclear translocation of the heterotrimeric CCAAT binding factor of Aspergillus oryzae is dependent on two redundant localising signals in a single subunit.

scientific article published on 21 October 2005

On the way toward systems biology of Aspergillus fumigatus infection

scientific article published on 08 May 2011

One step closer to precision medicine for infectious diseases

scientific article published on 02 May 2019

Opposed effects of enzymatic gliotoxin N- and S-methylations

scientific article published on 7 August 2014

Optimisation of a 2-D gel electrophoresis protocol for the human-pathogenic fungus Aspergillus fumigatus

scientific article published on 17 December 2005

PLB-985 Neutrophil-Like Cells as a Model To Study Aspergillus fumigatus Pathogenesis

scientific article published on 05 January 2022

Pathobiology of human-pathogenic fungi

scientific article published on 10 May 2011

Phagocyte responses towards Aspergillus fumigatus.

scientific article published on 14 May 2011

Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2

scientific article published on 31 August 2006

Phagocytosis of melanized Aspergillus conidia by macrophages exerts cytoprotective effects by sustained PI3K/Akt signalling

scientific article published on 31 May 2011

Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

scientific article published on 08 May 2020

Phenotypic and Proteomic Analysis of the Aspergillus fumigatus ΔPrtT, ΔXprG and ΔXprG/ΔPrtT Protease-Deficient Mutants

scientific article published on 12 December 2017

Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus.

scientific article published on 11 April 2016

Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA

scientific article

Production of pyomelanin, a second type of melanin, via the tyrosine degradation pathway in Aspergillus fumigatus

scientific article published on 21 November 2008

Protein kinase A regulates growth, sporulation, and pigment formation in Aspergillus fumigatus

scientific article published on 6 June 2008

Protein kinase C (PkcA) of Aspergillus nidulans is involved in penicillin production

scientific article

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus

article

Proteome analysis for pathogenicity and new diagnostic markers for Aspergillus fumigatus

scientific article published on 10 June 2008

Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin

scientific article published on 23 May 2012

Proteome profiling and functional classification of intracellular proteins from conidia of the human-pathogenic mold Aspergillus fumigatus

scientific article

Proteomic Profiling of Serological Responses to Aspergillus fumigatus Antigens in Patients with Invasive Aspergillosis

scientific article published on 14 March 2016

Proteomics of Aspergillus fumigatus conidia-containing phagolysosomes identifies processes governing immune evasion.

scientific article

Pyomelanin formation in Aspergillus fumigatus requires HmgX and the transcriptional activator HmgR but is dispensable for virulence

scientific article

Quantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to Pulmonary Aspergillus fumigatus Infection

scientific article published on 26 September 2017

Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus

scientific article published in Nature

Reconstitution of Enzymatic Carbon–Sulfur Bond Formation Reveals Detoxification-Like Strategy in Fungal Toxin Biosynthesis

scientific article published on 17 August 2018

Recreation of in-host acquired single nucleotide polymorphisms by CRISPR-Cas9 reveals an uncharacterised gene playing a role in Aspergillus fumigatus azole resistance via a non-cyp51A mediated resistance mechanism

scientific article published on 23 May 2019

Redox Proteomic Analysis Reveals Oxidative Modifications of Proteins by Increased Levels of Intracellular Reactive Oxygen Species during Hypoxia Adaptation of Aspergillus fumigatus

Regio- and Stereoselective Oxidative Phenol Coupling inAspergillus niger

scientific article published on 03 September 2012

Regulation and Role of Fungal Secondary Metabolites.

scientific article

Regulation of Penicillin Biosynthesis in Filamentous Fungi

Regulation of penicillin biosynthesis in filamentous fungi

scientific article

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans

scientific article

Regulatory cross talk and microbial induction of fungal secondary metabolite gene clusters

scientific article published on 01 January 2012

Regulatory interactions for iron homeostasis in Aspergillus fumigatus inferred by a Systems Biology approach

scientific article

Reversible Oxidation of a Conserved Methionine in the Nuclear Export Sequence Determines Subcellular Distribution and Activity of the Fungal Nitrate Regulator NirA

scientific article

Rewiring of the Austinoid Biosynthetic Pathway in Filamentous Fungi.

scientific article published on 27 October 2017

SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus

scientific article

Secreted Aspergillus fumigatus protease Alp1 degrades human complement proteins C3, C4, and C5.

scientific article

Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein

scientific article

SreA-mediated iron regulation in Aspergillus fumigatus

scientific article (publication date: October 2008)

Star-shaped drug carriers for doxorubicin with POEGMA and POEtOxMA brush-like shells: a structural, physical, and biological comparison

scientific article published on 5 July 2013

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

scientific article

Stress-Induced Changes in the Lipid Microenvironment of β-(1,3)-d-Glucan Synthase Cause Clinically Important Echinocandin Resistance in Aspergillus fumigatus.

scientific article published on 4 June 2019

Structural basis of HapEP88L-linked antifungal triazole resistance in Aspergillus fumigatus

scientific article published on 28 May 2020

Surface hydrophobin prevents immune recognition of airborne fungal spores

scientific article

Surface structure characterization of Aspergillus fumigatus conidia mutated in the melanin synthesis pathway and their human cellular immune response

scientific article

Synergistic activity of cosecreted natural products from amoebae-associated bacteria

scientific article published on 28 March 2018

Synthetic biology of fungal natural products

scientific article (publication date: 2015)

Synthetic biology tools for bioprospecting of natural products in eukaryotes

scientific article published on 13 March 2014

Systems biology of fungal infection.

scientific article published on 2 April 2012

Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin

scientific article published on 21 February 2020

Targeting of phagolysosomes containing conidia of the fungus Aspergillus fumigatus with polymeric particles

scientific article published in 2022

The Arthroderma benhamiae hydrophobin HypA mediates hydrophobicity and influences recognition by human immune effector cells

scientific article published on 9 March 2012

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

scientific article published on 16 April 2015

The Aspergillus fumigatus conidial melanin production is regulated by the bifunctional bHLH DevR and MADS-box RlmA transcription factors

scientific article published on 9 July 2016

The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model

scientific article

The CCAAT-binding complex (CBC) in Aspergillus species

scientific article published on 8 December 2016

The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes

scientific article

The CCAAT-binding complex of eukaryotes: evolution of a second NLS in the HapB subunit of the filamentous fungus Aspergillus nidulans despite functional conservation at the molecular level between yeast, A.nidulans and human

scientific article published in September 2005

The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus

scientific article published on 14 September 2016

The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess

scientific article

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

scientific article published on 30 August 2011

The MpkA MAP kinase module regulates cell wall integrity signaling and pyomelanin formation in Aspergillus fumigatus.

scientific article published on 26 August 2009

The Pheromone Module SteC-MkkB-MpkB-SteD-HamE Regulates Development, Stress Responses and Secondary Metabolism in Aspergillus fumigatus

scientific article published on 07 May 2020

The Role of RodA-Conserved Cysteine Residues in the Aspergillus fumigatus Conidial Surface Organization

scientific article published on 26 August 2020

The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus

scientific article published on 26 October 2018

The akuB(KU80) mutant deficient for nonhomologous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatus

scientific article

The cyclic AMP-dependent protein kinase a network regulates development and virulence in Aspergillus fumigatus

scientific article published on September 2004

The domestic pig as human-relevant large animal model to study adaptive anti-fungal immune responses against airborne Aspergillus fumigatus

scientific article published on 19 June 2020

The fungal CCAAT-binding complex and HapX display highly variable but evolutionary conserved synergetic promoter-specific DNA recognition

scientific article published on 22 February 2020

The hypoxia-induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence of Aspergillus fumigatus

scientific article published on 17 March 2016

The light-dependent regulator velvet A of Aspergillus nidulans acts as a repressor of the penicillin biosynthesis

scientific article published on 21 March 2007

The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response

scientific article published on 25 September 2007

The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus

scientific article published on 16 September 2019

The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus

scientific article published on 7 July 2014

The opportunistic human pathogenic fungus Aspergillus fumigatus evades the host complement system

scientific article published on 26 November 2007

The thioredoxin system of the filamentous fungus Aspergillus nidulans: impact on development and oxidative stress response.

scientific article published on 13 July 2007

The transcriptional regulators SteA and StuA contribute to keratin degradation and sexual reproduction of the dermatophyte Arthroderma benhamiae

scientific article published on 11 May 2016

Towards Raman spectroscopy of urine as screening tool

scientific article published on 19 November 2019

Transannular disulfide formation in gliotoxin biosynthesis and its role in self-resistance of the human pathogen Aspergillus fumigatus

scientific article published in July 2010

Transcriptome analysis of Aspergillus fumigatus exposed to voriconazole

article published in 2006

Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus

scientific article published on 11 March 2015

Two induced fungal polyketide pathways converge into antiproliferative spiroanthrones

scientific article

Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus

scientific article

UV-Raman Spectroscopic Identification of Fungal Spores Important for Respiratory Diseases

scientific article published on 16 July 2018

Virulence determinants of the human pathogenic fungus Aspergillus fumigatus protect against soil amoeba predation

scientific article published on 12 February 2015

Yeast two-hybrid screening reveals a dual function for the histone acetyltransferase GcnE by controlling glutamine synthesis and development in Aspergillus fumigatus

article