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List of works by Robert Weinberg

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

scientific article

A cyclin associated with the CDK-activating kinase MO15

scientific article (publication date: 15 September 1994)

A mouse model of human breast cancer metastasis to human bone

scientific article published on July 2005

A perspective on cancer cell metastasis

scientific article

A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis

scientific article

A progression puzzle

scientific article

Absence of rearrangements in the tumour susceptibility gene TSG101 in human breast cancer ⬇️

scientific article (publication date: August 1997)

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

scientific article

Activation of miR-31 function in already-established metastases elicits metastatic regression

scientific article

Adaptation versus selection: the origins of metastatic behavior

scientific article published on December 2007

An interaction between p21ras and heat shock protein hsp60, a chaperonin

scientific article

Assaying microRNA loss-of-function phenotypes in mammalian cells: emerging tools and their potential therapeutic utility

scientific article

Association of Cdk-activating kinase subunits with transcription factor TFIIH

scientific article (publication date: 16 March 1995)

Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

scientific article

Bengt Westermark and our current understanding of tumor pathogenesis

scientific article published in May 2012

Best practices for smoking cessation interventions in primary care

scientific article

Cancer cell of origin: spotlight on luminal progenitors

scientific article

Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links

scientific article published on 23 April 2012

Cancer stem cells: mirage or reality?

scientific article

Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling

scientific article published on 03 July 2012

Cell plasticity and heterogeneity in cancer.

scientific article published on 06 December 2012

Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase

scientific article

Chemokine networks and breast cancer metastasis.

scientific article published on January 2006

Coming full circle-from endless complexity to simplicity and back again

scientific article published on March 2014

Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis

scientific article published on 29 October 2009

Concurrent suppression of integrin alpha5, radixin, and RhoA phenocopies the effects of miR-31 on metastasis

scientific article

Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence

scholarly article

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

scientific article

Creation of human tumour cells with defined genetic elements

scientific article (publication date: 29 July 1999)

Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition

scientific article

Direct and Indirect Regulators of Epithelial-Mesenchymal Transition (EMT)-mediated Immunosuppression in Breast Carcinomas

scientific article published on 16 December 2020

Distinct EMT programs control normal mammary stem cells and tumour-initiating cells

scientific article

Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies

scientific article

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

scientific article

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

scientific article published on 11 April 2017

Emerging Biological Principles of Metastasis

scientific article published on February 2017

Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity

scientific article

Enumeration of the simian virus 40 early region elements necessary for human cell transformation

scientific article

Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer

scientific article published on 04 June 2010

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

scientific article

Exploring a new twist on tumor metastasis

scientific article

Expression cloning and characterization of the TGF-beta type III receptor

scientific article

Functional genomics and the breast cancer problem

scientific article

Genetically Defined, Syngeneic Organoid Platform for Developing Combination Therapies for Ovarian Cancer

scientific article published on 06 November 2020

Genetically defined syngeneic mouse models of ovarian cancer as tools for the discovery of combination immunotherapy

scientific article published on 06 November 2020

Growth suppression by p16ink4 requires functional retinoblastoma protein

scientific article

Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression

scientific article published on July 2008

Hallmarks of Cancer: The Next Generation ⬇️

scientific article published on March 4, 2011

High efficiency creation of human monoclonal antibody-producing hybridomas

scientific article

Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice

scientific article

Identification of selective inhibitors of cancer stem cells by high-throughput screening

scientific article

Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen

scientific article

Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

scientific article

Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells

scientific article published on 07 March 2017

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

scientific article (publication date: October 1999)

Isolation of a transforming sequence from a human bladder carcinoma cell line ⬇️

scientific article published on May 1, 1982

LACTB is a tumour suppressor that modulates lipid metabolism and cell state

scientific article

Mechanisms of malignant progression

scientific article

Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers

scientific article

Metastatic colonization: Settlement, adaptation and propagation of tumor cells in a foreign tissue environment ⬇️

scientific article published on 09 December 2010

MicroRNAs in malignant progression

scientific article published on 31 December 2007

MicroRNAs: Crucial multi-tasking components in the complex circuitry of tumor metastasis

scientific article

Micromanagers of malignancy: role of microRNAs in regulating metastasis

scientific article published on 31 July 2008

Modelling the molecular circuitry of cancer

scientific article

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

scientific article published on May 1, 1992

Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells

scientific article published on 12 April 2016

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

scientific article

Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast

scientific article published on June 2011

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

scientific article (publication date: 24 April 1997)

Physical interaction of the retinoblastoma protein with human D cyclins

scientific article

Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

scientific article published on 16 September 2020

Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity

scientific article published on July 2013

Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells

scientific article

Reconstruction of functionally normal and malignant human breast tissues in mice

scholarly article

Requirement for TFIIH kinase activity in transcription by RNA polymerase II

scientific article

Retrospective: Judah Folkman (1933-2008).

scientific article

Rules for making human tumor cells

scientific article

Senescence: does it all happen at the ends?

scientific article

Slug and Sox9 cooperatively determine the mammary stem cell state

scientific article

Stromal fibroblasts in cancer: a novel tumor-promoting cell type

scientific article published on August 2006

Systemic endocrine instigation of indolent tumor growth requires osteopontin

scientific article

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

scientific article

Tackling the cancer stem cells - what challenges do they pose?

scientific article

Taking the study of cancer cell survival to a new dimension

scientific article

Targeting the Epithelial-to-Mesenchymal Transition: The Case for Differentiation-Based Therapy

scientific article published on 5 January 2017

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

scientific article

Telomeres: cancer to human aging

scientific article published on January 2006

The Hallmarks of Cancer

2000 paper by Hanahan and Weinberg

The N-terminal and C-terminal domains of a receptor tyrosine phosphatase are associated by non-covalent linkage

scientific article (publication date: June 1992)

The Spemann organizer gene, Goosecoid, promotes tumor metastasis

scientific article

The basics of epithelial-mesenchymal transition

scientific article

The epigenetics of epithelial-mesenchymal plasticity in cancer

scientific article

The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming

scientific article

The epithelial-mesenchymal transition generates cells with properties of stem cells

scientific article

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

scientific article

The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions

scientific article

The retinoblastoma protein and cell cycle control

scientific article (publication date: 5 May 1995)

The signaling domain of the erythropoietin receptor rescues prolactin receptor-mutant mammary epithelium

scientific article

The signals and pathways activating cellular senescence

scientific article

The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy.

scientific article published in April 2018

The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis

scientific article published on August 2014

Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

scientific article

Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells ⬇️

scientific article published on September 30, 1997

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

scientific article (publication date: April 2009)

Treatment of attention deficit hyperactivity disorder with monoamine amino acid precursors and organic cation transporter assay interpretation

scientific article

Tumor-host interactions: a far-reaching relationship

scientific article published on 19 July 2010

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes ⬇️

scientific article published on August 18, 1983

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

scientific article (publication date: 11 October 2007)

When cells get stressed: an integrative view of cellular senescence

scientific article published on January 2004

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization ⬇️

scientific article published on August 22, 1997

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

scientific article

miR-31: a crucial overseer of tumor metastasis and other emerging roles

scientific article

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

scientific article

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