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List of works by Andrew F. James

A TRPC-like non-selective cation current activated by alpha 1-adrenoceptors in rat mesenteric artery smooth muscle cells

scientific article published on 11 May 2006

A fast transient outward current in cultured cells from human pulmonary artery smooth muscle.

scientific article published in June 1995

A hERG mutation E1039X produced a synergistic lesion on IKs together with KCNQ1-R174C mutation in a LQTS family with three compound mutations

scientific article published on 15 February 2018

A multicentre study of patients with Timothy syndrome.

scientific article published on 24 March 2017

Actions of the anti-oestrogen agent clomiphene on outward K+ currents in rat ventricular myocytes.

scientific article published in January 2004

Activation of glibenclamide-sensitive ATP-sensitive K+ channels during β-adrenergically induced metabolic stress produces a substrate for atrial tachyarrhythmia

scientific article published on 16 November 2012

Acute desensitization of acetylcholine and endothelin-1 activated inward rectifier K+ current in myocytes from the cardiac atrioventricular node.

scientific article published on 5 June 2012

Alterations in outward K(+) currents on removal of external Ca(2+) in human atrial myocytes

scientific article published on 01 June 2000

Altered Na/Ca exchange distribution in ventricular myocytes from failing hearts.

scientific article published on 13 November 2015

Altered distribution of ICa impairs Ca release at the t-tubules of ventricular myocytes from failing hearts.

scientific article published on 20 June 2015

An altered repolarizing potassium current in rat cardiac myocytes after subtotal nephrectomy

scientific article published on 01 September 2000

Atrial remodeling and the substrate for atrial fibrillation in rat hearts with elevated afterload

scientific article published on 23 August 2011

Atrial-ventricular differences in rabbit cardiac voltage-gated Na+ currents: Basis for atrial-selective block by ranolazine

scientific article published on 10 June 2017

Cardiac background sodium current: Elusive but important

scientific article published on July 2016

Cardiac ion channel current modulation by the CFTR inhibitor GlyH-101

scientific article published on 31 March 2011

Cardiac-specific overexpression of caveolin-3 preserves t-tubular I during heart failure in mice

scientific article published on 14 March 2019

Caveolin 3-dependent loss of t-tubular ICa during hypertrophy and heart failure in mice.

scientific article published on 23 February 2018

Caveolin-3 KO disrupts t-tubule structure and decreases t-tubular ICa density in mouse ventricular myocytes

scientific article published on 20 July 2018

Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload.

scientific article published on 29 December 2015

Characterization and influence of cardiac background sodium current in the atrioventricular node

scientific article published on 27 April 2016

Cholesterol depletion does not alter the capacitance or Ca handling of the surface or t-tubule membranes in mouse ventricular myocytes.

scientific article published in November 2017

Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion

scientific article

Compound Heterozygous Triadin Mutation Causing Cardiac Arrest in Two Siblings

scientific article published on 02 March 2016

Do t-tubules play a role in arrhythmogenesis in cardiac ventricular myocytes?

scientific article published on 07 May 2013

ETA and ETB receptors on single smooth muscle cells cooperate in mediating guinea pig tracheal contraction

scientific article published on 01 February 1994

Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats

scientific article

Effects of endothelin-1 on K(+) currents from rat ventricular myocytes.

scientific article published in June 2001

Electrophysiological properties of myocytes isolated from the mouse atrioventricular node: L-type ICa, IKr, If, and Na-Ca exchange

scientific article published on November 2015

Endothelin antagonists in renal disease

scientific article published on 01 August 1997

Evidence for a novel K(+) channel modulated by alpha(1A)-adrenoceptors in cardiac myocytes.

scientific article

Expression of voltage-gated K+ channels in human atrium.

scientific article published in November 2002

Functional and cardioprotective effects of simultaneous and individual activation of protein kinase A and Epac

scientific article published on 10 January 2017

Gender-related differences in ventricular myocyte repolarization in the guinea pig.

scientific article

Heterogeneity of T-Tubules in Pig Hearts.

scientific article

Increased susceptibility to atrial tachyarrhythmia in spontaneously hypertensive rat hearts

scientific article published on 22 January 2007

Inflammation, oxidative stress and postoperative atrial fibrillation in cardiac surgery

scientific article

Inhibition of SR Ca2+ uptake: a novel action of the RyR2-FKBP12.6 antagonist K201.

scientific article

Inhibition of a TREK-like K+ channel current by noradrenaline requires both β1- and β2-adrenoceptors in rat atrial myocytes.

scientific article published on 9 September 2014

Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656

scientific article published on 07 March 2006

Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin.

scientific article published on 3 May 2007

Inhibition of the cardiac protein kinase A-dependent chloride conductance by endothelin-1

scientific article published in Nature

Ion currents, action potentials, and noradrenergic responses in rat pulmonary vein and left atrial cardiomyocytes

scientific article published on 01 May 2020

Is there a transient rise in sub-sarcolemmal Na and activation of Na/K pump current following activation of I(Na) in ventricular myocardium?

scientific article

L-type calcium current of isolated rat cardiac myocytes in experimental uraemia

scientific article published on 01 June 2000

Loss of caveolin-3-dependent regulation of ICa in rat ventricular myocytes in heart failure

scientific article published on 3 November 2017

Modulation by Endothelin-1 of Spontaneous Activity and Membrane Currents of Atrioventricular Node Myocytes from the Rabbit Heart ⬇️

scientific article published on March 29, 2012

More types than one: multiple muscarinic receptor coupled K+ currents undergo remodelling in an experimental model of atrial fibrillation

scientific article

Negative inotropic effects of endothelin-1 in mouse cardiomyocytes: evidence of a role for Na+-Ca2+ exchange.

scientific article

Nickel inhibits β-1 adrenoceptor mediated activation of cardiac CFTR chloride channels.

scientific article published on 31 January 2013

Novel ion channel targets in atrial fibrillation.

scientific article published on 26 February 2016

Potent hERG channel inhibition by sarizotan, an investigative treatment for Rett Syndrome

scientific article published on 27 July 2019

QT interval prolongation and torsades de pointes with oxaliplatin.

scientific article published on 15 November 2016

Recent advances in understanding sex differences in cardiac repolarization.

scientific article

Reduced density and altered regulation of rat atrial L-type Ca2+ current in heart failure

scientific article published on 6 December 2016

Refining insights into high-affinity drug binding to the human ether-à-go-go-related gene potassium channel.

scientific article published on April 2008

Role of SK channel activation in determining the action potential configuration in freshly isolated human atrial myocytes from the SKArF study

scientific article published on 25 March 2019

Sarcolemmal distribution of ICa and INCX and Ca2+ autoregulation in mouse ventricular myocytes

scientific article published on 5 May 2017

Selective activation of heteromeric SK channels contributes to action potential repolarization in mouse atrial myocytes

scientific article published on 22 January 2015

Short QT interval linked to androgen misuse: wider significance and possible basis

scientific article published on 01 July 2009

Stimulation of ICa by basal PKA activity is facilitated by caveolin-3 in cardiac ventricular myocytes

scientific article

The effects of aging on the regulation of t-tubular ICa by caveolin in mouse ventricular myocytes

scientific article published on 9 December 2017

The effects of endothelin-1 on the PKA-dependent Cl- current in the heart

scientific article published on 01 January 1994

The mechanism and control of rabbit oviduct fluid formation

scientific article published on 01 November 1988

The neuroprotective agent sipatrigine blocks multiple cardiac ion channels and causes triangulation of the ventricular action potential.

scientific article published in December 2005

The sodium channel Nav1.5a is the predominant isoform expressed in adult mouse dorsal root ganglia and exhibits distinct inactivation properties from the full-length Nav1.5 channel.

scientific article published on 13 March 2007

VEGF activates receptor-operated cation channels in human microvascular endothelial cells.

scientific article published on 8 June 2006

β-Adrenoceptor/PKA-stimulation, Na(+)-Ca(2+) exchange and PKA-activated Cl(-) currents in rabbit cardiomyocytes: a conundrum.

scientific article published on 25 March 2011

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