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List of works by Yenamandra S. Prabhakar

A QSAR study on 2-(4-methylpiperazin-1-yl)quinoxalines as human histamine H4 receptor ligands

scientific article published on 13 October 2010

A high dimensional QSAR study on the aldose reductase inhibitory activity of some flavones: topological descriptors in modeling the activity

scientific article published on 01 January 2006

A quantitative structure-activity relationship study on serotonin 5-HT6) receptor ligands: indolyl and piperidinyl sulphonamides.

scientific article published in April 2010

Arylpiperazines for management of benign prostatic hyperplasia: design, synthesis, quantitative structure-activity relationships, and pharmacokinetic studies.

scientific article published on 3 December 2010

C-3 alkyl/arylalkyl-2,3-dideoxy hex-2-enopyranosides as antitubercular agents: synthesis, biological evaluation, and QSAR study.

scientific article published on 2 June 2007

CP-MLR directed QSAR studies on the antimycobacterial activity of functionalized alkenols--topological descriptors in modeling the activity

scientific article published on 01 January 2005

CP-MLR/PLS directed QSAR study on apical sodium-codependent bile acid transporter inhibition activity of benzothiepines

scientific article published on 13 January 2010

CP-MLR/PLS directed QSAR study on the glutaminyl cyclase inhibitory activity of imidazoles: rationales to advance the understanding of activity profile

scientific article published on 05 February 2012

Chemo- and bioinformatics in the discovery of antimalarial drugs and arthropod repellents to counter vector borne diseases (VBDs).

scientific article published in September 2013

Chemometric descriptors in modeling the carbonic anhydrase inhibition activity of sulfonamide and sulfamate derivatives

scientific article published on 06 August 2009

CoMFA and CoMSIA analysis of tetrahydroquinolines as potential antimalarial agents

scientific article published on 23 May 2011

CoMFA and CoMSIA of diverse pyrrolidine analogues as dipeptidyl peptidase IV inhibitors: active site requirements

scientific article published on 25 August 2010

Combinatorial protocol in multiple linear regression/partial least-squares directed rationale for the caspase-3 inhibition activity of isoquinoline-1,3,4-trione derivatives.

scientific article published in January 2010

Consensus features of CP-MLR and GA in modeling HIV-1 RT inhibitory activity of 4-benzyl/benzoylpyridin-2-one analogues.

scientific article published in February 2011

Correlation of biological activities of mesoionic and benz-fused mesoionic xanthine analogs with van der Waals volume and molecular connectivity ⬇️

scientific article published on June 1, 1984

Cypermethrin induces astrocyte apoptosis by the disruption of the autocrine/paracrine mode of epidermal growth factor receptor signaling.

scientific article published in November 2011

Discovery of triazine mimetics as potent antileishmanial agents.

scientific article

Graph theory concepts in the rationales of anti HIV-1 compounds.

scientific article published on December 2013

Hepatoprotective effects of Wedelia calendulacea

scientific article published on 01 February 1989

Identification of adjacent NNRTI binding pocket in multi-mutated HIV1-RT Enzyme Model: An in silico study

scientific article published on 12 April 2018

In Silico Exploration for New Antimalarials: Arylsulfonyloxy Acetimidamides as Prospective Agents.

scientific article published on 3 August 2015

Investigation of HDAC8-ligands' intermolecular forces through molecular dynamics simulations: profiling of non-bonding energies to design potential compounds as new anti-cancer agents

scientific article published on 24 June 2020

Modeling of LIM-Kinase 2 inhibitory activity of pyrrolopyrimidine analogues: useful in treatment of ocular hypertension and glaucoma.

scientific article

Modeling of vascular endothelial growth factor receptor 2 (VEGFR2) kinase inhibitory activity of 2-anilino-5-aryloxazoles using chemometric tools

scientific article published in February 2009

Modelling of serotonin reuptake inhibitory and histamine H₃antagonistic activity of piperazine and diazepane amides: QSAR rationales for co-optimization of the activity profiles.

scientific article

Molecular dynamics study of HDAC8-largazole analogues co-crystals for designing potential anticancer compounds

scientific article published on 20 April 2019

Pyridones as NNRTIs against HIV-1 mutants: 3D-QSAR and protein informatics ⬇️

scientific article published on July 25, 2013

QSAR of 2-(4-methylsulphonylphenyl)pyrimidine derivatives as cyclooxygenase-2 inhibitors: simple structural fragments as potential modulators of activity

scientific article published on 16 June 2011

QSAR studies on benzoylaminobenzoic acid derivatives as inhibitors of beta-ketoacyl-acyl carrier protein synthase III.

scientific article published on 10 July 2007

QSAR study on tetrahydroquinoline analogues as plasmodium protein farnesyltransferase inhibitors: a comparison of rationales of malarial and mammalian enzyme inhibitory activities for selectivity.

scientific article published in February 2008

Retracted: Chemotherapeutic Potential of 2-[Piperidinoethoxyphenyl]-3-Phenyl-2H-Benzo(b)pyran in Estrogen Receptor- Negative Breast Cancer Cells: Action via Prevention of EGFR Activation and Combined Inhibition of PI-3-K/Akt/FOXO and MEK/Erk/AP-1

retracted article

Spiro-oxindole derivative 5-chloro-4',5'-diphenyl-3'-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro[indoline-3,2'-pyrrolidin]-2-one triggers apoptosis in breast cancer cells via restoration of p53 function.

scientific article published on 7 November 2015

Synthesis and QSAR studies on thiazolidinones as anti-HIV agents.

scientific article published on August 2005

Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents.

scientific article

Synthesis, biological evaluation and molecular modeling studies of new 2,3-diheteroaryl thiazolidin-4-ones as NNRTIs

scientific article published on 29 May 2015

Target based drug design - a reality in virtual sphere.

scientific article

Topological and physicochemical characteristics of 1,2,3,4-Tetrahydroacridin- 9(10H)-ones and their antimalarial profiles: a composite insight to the structure-activity relation

scientific article published in September 2013

Topological descriptors in modeling malonyl coenzyme A decarboxylase inhibitory activity: N-Alkyl-N-(1,1,1,3,3,3-hexafluoro-2-hydroxypropylphenyl)amide derivatives

scientific article published in February 2009

Topological descriptors in modeling the HIV inhibitory activity of 2-aryl-3-pyridyl-thiazolidin-4-ones

scientific article published on 01 August 2005

Topological descriptors in modeling the antimalarial activity of 4-(3',5'-disubstituted anilino)quinolines.

scientific article published in January 2006

Topological descriptors in modelling antimalarial activity: N(1)-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine as prototype

scientific article published in February 2009

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