List of works - Arnold J. Levine

A plausible model for the digital response of p53 to DNA damage.

scientific article

A polymorphic variant in human MDM4 associates with accelerated age of onset of estrogen receptor negative breast cancer

scientific article published on 16 September 2009

A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells

scientific article published on March 2007

A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect

scientific article

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

scientific article

Chronic restraint stress attenuates p53 function and promotes tumorigenesis

scientific article

Comparison of the human and worm p53 structures suggests a way for enhancing stability

scientific article

Comparison of the protein-protein interfaces in the p53-DNA crystal structures: towards elucidation of the biological interface

scientific article

Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations

scholarly article

Detection of functional single-nucleotide polymorphisms that affect apoptosis

scientific article

Differential levels of transcription of p53-regulated genes by the arginine/proline polymorphism: p53 with arginine at codon 72 favors apoptosis.

scientific article

Dipeptide analysis of p53 mutations and evolution of p53 family proteins.

scientific article published on 10 April 2013

Gene Amplifications in Well-Differentiated Pancreatic Neuroendocrine Tumors Inactivate the p53 Pathway.

scientific article

Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models

scientific article published on 29 December 2020

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

scientific article

In the quest for stable rescuing mutants of p53: computational mutagenesis of flexible loop L1.

scientific article

MDM2 is a central node in the p53 pathway: 12 years and counting

scientific article

Multiple Roles of p53-Related Pathways in Somatic Cell Reprogramming and Stem Cell Differentiation ⬇️

scientific article published on September 10, 2012

Negative regulation of tumor suppressor p53 by microRNA miR-504

scientific article

Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect ⬇️

scientific article published on September 19, 2011

Reconstructing signal transduction pathways: challenges and opportunities.

scientific article published on 12 October 2007

Regulation of female reproduction by p53 and its family members

scientific article

Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targets

scientific article published on 16 April 2007

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

scientific article

The Regulation of Multiple p53 Stress Responses is Mediated through MDM2 ⬇️

scientific article published on March 1, 2012

The contribution of the Trp/Met/Phe residues to physical interactions of p53 with cellular proteins

scientific article

The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein

scientific article published in 2022

The origins and evolution of the p53 family of genes

scientific article

The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways

scientific article published on April 2007

The regulation of human reproduction by p53 and its pathway

scientific article published on 01 November 2009

The tumor suppressor p53: cancer and aging

scientific article published on 23 January 2008

Tumour-associated mutant p53 drives the Warburg effect

scientific article published on January 2013

Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia

scientific article published on 02 April 2009

p53 regulates maternal reproduction through LIF

scientific article

p53: a new player in reproduction

scientific article published on 23 January 2008

List of works by Arnold J. Levine

A plausible model for the digital response of p53 to DNA damage.

A polymorphic variant in human MDM4 associates with accelerated age of onset of estrogen receptor negative breast cancer

A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells

A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

Chronic restraint stress attenuates p53 function and promotes tumorigenesis

Comparison of the human and worm p53 structures suggests a way for enhancing stability

Comparison of the protein-protein interfaces in the p53-DNA crystal structures: towards elucidation of the biological interface

Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations

Detection of functional single-nucleotide polymorphisms that affect apoptosis

Differential levels of transcription of p53-regulated genes by the arginine/proline polymorphism: p53 with arginine at codon 72 favors apoptosis.

Dipeptide analysis of p53 mutations and evolution of p53 family proteins.

Gene Amplifications in Well-Differentiated Pancreatic Neuroendocrine Tumors Inactivate the p53 Pathway.

Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

In the quest for stable rescuing mutants of p53: computational mutagenesis of flexible loop L1.

MDM2 is a central node in the p53 pathway: 12 years and counting

Multiple Roles of p53-Related Pathways in Somatic Cell Reprogramming and Stem Cell Differentiation ⬇️

Negative regulation of tumor suppressor p53 by microRNA miR-504

Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect ⬇️

Reconstructing signal transduction pathways: challenges and opportunities.

Regulation of female reproduction by p53 and its family members

Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targets

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

The Regulation of Multiple p53 Stress Responses is Mediated through MDM2 ⬇️

The contribution of the Trp/Met/Phe residues to physical interactions of p53 with cellular proteins

The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein

The origins and evolution of the p53 family of genes

The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways

The regulation of human reproduction by p53 and its pathway

The tumor suppressor p53: cancer and aging

Tumour-associated mutant p53 drives the Warburg effect

Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia

p53 regulates maternal reproduction through LIF

p53: a new player in reproduction