List of works - Adeline Hajjar

A Francisella mutant in lipid A carbohydrate modification elicits protective immunity.

scientific article

A Novel Class of Small Molecule Agonists with Preference for Human over Mouse TLR4 Activation

scientific article

A model system for nonhomologous recombination between retroviral and cellular RNA ⬇️

scientific article published on July 1, 1993

Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.

scientific article

Bordetella parapertussis PagP mediates the addition of two palmitates to the lipopolysaccharide lipid A.

scientific article

Bordetella pertussis Lipid A Recognition by Toll-like Receptor 4 and MD-2 Is Dependent on Distinct Charged and Uncharged Interfaces

scientific article published on 2 April 2015

CFTR dysregulation drives active selection of the gut microbiome

scientific article published on 21 January 2020

Characterization of a unique retroviral recombinant containing 7S L sequences.

scientific article published on December 1993

Chronic sialodacryoadenitis virus (SDAV) infection in athymic rats

scientific article published on January 1, 1991

Comparison of a cheetah herpesvirus isolate to feline herpesvirus type 1

scientific article published on 01 January 1988

Cutaneous fibropapillomas of green turtles (Chelonia mydas)

scientific article published in July 1989

Cutting Edge: Protective Cell-Mediated Immunity to Listeria monocytogenes in the Absence of Myeloid Differentiation Factor 88

scientific article published on 01 July 2003

Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin

scientific journal article

Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus.

scientific article published in March 2004

Early evolutionary loss of the lipid A modifying enzyme PagP resulting in innate immune evasion in Yersinia pestis

scientific article published on 31 August 2020

Expression level of human TLR4 rather than sequence is the key determinant of LPS responsiveness

scientific article published on 11 October 2017

Expression of human TLR4/myeloid differentiation factor 2 directs an early innate immune response associated with modest increases in bacterial burden during Coxiella burnetii infection

scientific article published on 10 June 2019

Ferreting Out the Role of Infection in Cystic Fibrosis Lung Disease.

scientific article

Human Toll-like receptor 4 recognizes host-specific LPS modifications.

scientific article published on 25 March 2002

Human gut bacteria contain acquired interbacterial defence systems

scientific article published on 30 October 2019

Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica

scientific article

Identification, cloning, expression, and purification of Francisella lpp3: an immunogenic lipoprotein.

scientific article

Induction of protective immunity to Listeria monocytogenes in neonates.

scientific article published on March 2007

Inhalation of Francisella novicida Delta mglA causes replicative infection that elicits innate and adaptive responses but is not protective against invasive pneumonic tularemia.

scientific article published on 22 April 2008

Innate immune detection of flagellin positively and negatively regulates salmonella infection.

scientific article

Innate immune recognition of, and response to, Clostridium sordellii.

scientific article

Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors

scientific article

Modification of retroviral RNA by double-stranded RNA adenosine deaminase.

scientific article

NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis.

scientific article

Neonatal innate TLR-mediated responses are distinct from those of adults.

scientific article

Polychromatic flow cytometric high-throughput assay to analyze the innate immune response to Toll-like receptor stimulation.

scientific article published on 16 May 2008

Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4.

scientific article published on September 2004

Potential for using a hermetically-sealed, positive-pressured isocage system for studies involving germ-free mice outside a flexible-film isolator

scientific article

Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4.

scientific article published on January 2003

Redundant Toll-like receptor signaling in the pulmonary host response to Pseudomonas aeruginosa.

scientific article

Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses.

scientific article published on 3 January 2012

TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages

scientific article published on 24 February 2016

Temporal and anatomical host resistance to chronic Salmonella infection is quantitatively dictated by Nramp1 and influenced by host genetic background

scientific article

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

scientific article

The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism

scientific article published on 23 December 2021

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

scientific journal article

Toll-like receptor-2 and -4 responses regulate neutrophil infiltration into the junctional epithelium and significantly contribute to the composition of the oral microbiota

scientific article published on 01 July 2019

Variability in the lipooligosaccharide structure and endotoxicity among Bordetella pertussis strains.

scientific article published on 4 November 2010

List of works by Adeline Hajjar

A Francisella mutant in lipid A carbohydrate modification elicits protective immunity.

A Novel Class of Small Molecule Agonists with Preference for Human over Mouse TLR4 Activation

A model system for nonhomologous recombination between retroviral and cellular RNA ⬇️

Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.

Bordetella parapertussis PagP mediates the addition of two palmitates to the lipopolysaccharide lipid A.

Bordetella pertussis Lipid A Recognition by Toll-like Receptor 4 and MD-2 Is Dependent on Distinct Charged and Uncharged Interfaces

CFTR dysregulation drives active selection of the gut microbiome

Characterization of a unique retroviral recombinant containing 7S L sequences.

Chronic sialodacryoadenitis virus (SDAV) infection in athymic rats

Comparison of a cheetah herpesvirus isolate to feline herpesvirus type 1

Cutaneous fibropapillomas of green turtles (Chelonia mydas)

Cutting Edge: Protective Cell-Mediated Immunity to Listeria monocytogenes in the Absence of Myeloid Differentiation Factor 88

Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin

Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus.

Early evolutionary loss of the lipid A modifying enzyme PagP resulting in innate immune evasion in Yersinia pestis

Expression level of human TLR4 rather than sequence is the key determinant of LPS responsiveness

Expression of human TLR4/myeloid differentiation factor 2 directs an early innate immune response associated with modest increases in bacterial burden during Coxiella burnetii infection

Ferreting Out the Role of Infection in Cystic Fibrosis Lung Disease.

Human Toll-like receptor 4 recognizes host-specific LPS modifications.

Human gut bacteria contain acquired interbacterial defence systems

Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica

Identification, cloning, expression, and purification of Francisella lpp3: an immunogenic lipoprotein.

Induction of protective immunity to Listeria monocytogenes in neonates.

Inhalation of Francisella novicida Delta mglA causes replicative infection that elicits innate and adaptive responses but is not protective against invasive pneumonic tularemia.

Innate immune detection of flagellin positively and negatively regulates salmonella infection.

Innate immune recognition of, and response to, Clostridium sordellii.

Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors

Modification of retroviral RNA by double-stranded RNA adenosine deaminase.

NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis.

Neonatal innate TLR-mediated responses are distinct from those of adults.

Polychromatic flow cytometric high-throughput assay to analyze the innate immune response to Toll-like receptor stimulation.

Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4.

Potential for using a hermetically-sealed, positive-pressured isocage system for studies involving germ-free mice outside a flexible-film isolator

Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4.

Redundant Toll-like receptor signaling in the pulmonary host response to Pseudomonas aeruginosa.

Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses.

TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages

Temporal and anatomical host resistance to chronic Salmonella infection is quantitatively dictated by Nramp1 and influenced by host genetic background

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

Toll-like receptor-2 and -4 responses regulate neutrophil infiltration into the junctional epithelium and significantly contribute to the composition of the oral microbiota

Variability in the lipooligosaccharide structure and endotoxicity among Bordetella pertussis strains.