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List of works by Robert Williams III

A New Extrudable Form of Hypromellose: AFFINISOL™ HPMC HME.

scientific article

A modified USP induction port to characterize nasal spray plume geometry and predict turbinate deposition under flow

scientific article published on 27 June 2018

A novel particle engineering technology to enhance dissolution of poorly water soluble drugs: spray-freezing into liquid.

scientific article

A novel particle engineering technology: spray-freezing into liquid.

scientific article published in August 2002

Aerosolized nanostructured itraconazole as prophylaxis against invasive pulmonary aspergillosis.

scientific article published on 13 March 2007

Amorphous compositions using concentration enhancing polymers for improved bioavailability of itraconazole.

scientific article

Amorphous cyclosporin nanodispersions for enhanced pulmonary deposition and dissolution.

scientific article

Application of co-grinding to formulate a model pMDI suspension

scientific article published on 01 September 1999

Applications of KinetiSol dispersing for the production of plasticizer free amorphous solid dispersions.

scientific article published on 15 March 2010

Atmospheric freeze drying for the reduction of powder electrostatics of amorphous, low density, high surface area pharmaceutical powders ⬇️

scientific article published on May 22, 2012

Bioavailability Improvement of Carbamazepine via Oral Administration of Modified-Release Amorphous Solid Dispersions in Rats

scientific article published on 26 October 2020

Bioavailability enhancement of a BCS IV compound via an amorphous combination product containing ritonavir.

scientific article published on 10 October 2015

CNS disorders--current treatment options and the prospects for advanced therapies

scientific article published in November 2008

Can drug release rate from implants be tailored using poly(urethane) mixtures?

scientific article published on 06 December 2018

Caveolin-1-derived peptide limits development of pulmonary fibrosis

scientific article published on 01 December 2019

Challenges and Strategies in Thermal Processing of Amorphous Solid Dispersions: A Review

scientific article published on 26 August 2015

Characterization and pharmacokinetic analysis of aerosolized aqueous voriconazole solution.

scientific article published in May 2009

Characterization and pharmacokinetic analysis of crystalline versus amorphous rapamycin dry powder via pulmonary administration in rats.

scientific article

Characterization and pharmacokinetic analysis of tacrolimus dispersion for nebulization in a lung transplanted rodent model.

scientific article published on 25 September 2009

Characterization of an inclusion complex of cholesterol and hydroxypropyl-beta-cyclodextrin

scientific article published on 01 November 1998

Compaction properties of microcrystalline cellulose and sodium sulfathiazole in combination with talc or magnesium stearate

scientific article published on 01 December 1989

Comparison of bioavailability of amorphous versus crystalline itraconazole nanoparticles via pulmonary administration in rats.

scientific article published on 25 January 2010

Cryogenic liquids, nanoparticles, and microencapsulation.

scientific article published on 28 April 2006

Current therapies and technological advances in aqueous aerosol drug delivery

scientific article published in September 2008

Delivery Technologies for Orally Inhaled Products: an Update

scientific article published on 19 February 2019

Design of potent amorphous drug nanoparticles for rapid generation of highly supersaturated media.

scientific article published on 24 August 2007

Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing

scientific article published on 22 October 2020

Development of an Excipient-Free Peptide Dry Powder Inhalation for the Treatment of Pulmonary Fibrosis

scientific article published on 08 January 2020

Dissolution enhancement of itraconazole by hot-melt extrusion alone and the combination of hot-melt extrusion and rapid freezing--effect of formulation and processing variables

scientific article

Drug delivery strategies for improved azole antifungal action

scientific article published on 01 November 2008

Drug nanoparticles by antisolvent precipitation: mixing energy versus surfactant stabilization.

scientific article published in October 2006

Dry powder insufflation of crystalline and amorphous voriconazole formulations produced by thin film freezing to mice

scientific article published on 01 May 2012

Effect of process variables on morphology and aerodynamic properties of voriconazole formulations produced by thin film freezing

scientific article published on 13 March 2012

Enabling thermal processing of ritonavir-polyvinyl alcohol amorphous solid dispersions by KinetiSol® Dispersing.

scientific article

Encapsulation of protein nanoparticles into uniform-sized microspheres formed in a spinning oil film.

scientific article published on 06 December 2005

Enhanced Aerosolization of High Potency Nanoaggregates of Voriconazole by Dry Powder Inhalation

scientific article published on 10 April 2019

Enhanced aqueous dissolution of a poorly water soluble drug by novel particle engineering technology: spray-freezing into liquid with atmospheric freeze-drying.

scientific article published in March 2003

Enhanced drug dissolution using evaporative precipitation into aqueous solution.

scientific article published in August 2002

Enhanced in vivo absorption of itraconazole via stabilization of supersaturation following acidic-to-neutral pH transition

scientific article published in August 2008

Evaluation of the USP dissolution test method A for enteric-coated articles by planar laser-induced fluorescence.

scientific article

Films loaded with insulin-coated nanoparticles (ICNP) as potential platforms for peptide buccal delivery

scientific article published on 23 June 2014

Flocculated amorphous itraconazole nanoparticles for enhanced in vitro supersaturation and in vivo bioavailability

scientific article published on 01 October 2011

Flocculation of polymer stabilized nanocrystal suspensions to produce redispersible powders

scientific article published in March 2009

Formation of stable submicron protein particles by thin film freezing.

scientific article

Formulation Composition and Process Affect Counterion for CSP7 Peptide

scientific article published on 29 September 2019

Formulation and delivery of improved amorphous fenofibrate solid dispersions prepared by thin film freezing

scientific article published on 05 September 2012

Formulation of a novel fixed dose combination of salmeterol xinafoate and mometasone furoate for inhaled drug delivery.

scientific article published on 25 July 2015

Formulation of a protein with propellant HFA 134a for aerosol delivery

scientific article published on 01 January 1999

Fusion production of solid dispersions containing a heat-sensitive active ingredient by hot melt extrusion and Kinetisol dispersing.

scientific article published on 7 October 2009

Has nanotechnology led to improved therapeutic outcomes?

scientific article published on February 2012

High bioavailability from nebulized itraconazole nanoparticle dispersions with biocompatible stabilizers.

scientific article published on 14 May 2008

Highly supersaturated solutions of amorphous drugs approaching predictions from configurational thermodynamic properties.

scientific article

Homogeneity of amorphous solid dispersions - an example with KinetiSol®

scientific article published on 25 January 2019

Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

scientific article published on 12 September 2016

Hot-melt extrusion--basic principles and pharmaceutical applications

scientific article published on 13 February 2014

How Do You Use AAPS PharmSciTech?

scientific article (publication date: February 2015)

Improvement of dissolution rates of poorly water soluble APIs using novel spray freezing into liquid technology.

scientific article published in September 2002

In vitro and in vivo performance of dry powder inhalation formulations: comparison of particles prepared by thin film freezing and micronization

scientific article

Influence of formulation and processing variables on properties of itraconazole nanoparticles made by advanced evaporative precipitation into aqueous solution.

scientific article

Influence of formulation technique for hydroxypropyl-beta-cyclodextrin on the stability of aspirin in HFA 134a

scientific article published on 01 March 1999

Influence of hydroxypropyl methylcellulose polymer on in vitro and in vivo performance of controlled release tablets containing alprazolam.

scientific article published in November 2003

Influence of metering chamber volume and water level on the emitted dose of a suspension-based pMDI containing propellant 134a

scientific article published on 01 April 1997

Influence of micronization method on the performance of a suspension triamcinolone acetonide pressurized metered-dose inhaler formulation

scientific article published on 01 May 1999

Influence of particle size on regional lung deposition--what evidence is there?

scientific article published on 11 January 2011

Influence of process parameters on the preparation of pharmaceutical films by electrostatic powder deposition.

scientific article published on 8 October 2016

Influence of processing and curing conditions on beads coated with an aqueous dispersion of cellulose acetate phthalate

scientific article published on 01 May 2000

Inhaled nanoparticles--a current review.

scientific article published on 16 February 2008

Inhaled voriconazole for prevention of invasive pulmonary aspergillosis.

scientific article published on 16 March 2009

Long-term stability of heat-humidity cured cellulose acetate phthalate coated beads.

scientific article published in March 2002

Modified release itraconazole amorphous solid dispersion to treat Aspergillus fumigatus: importance of the animal model selection.

scientific article

Moisture uptake and its influence on pressurized metered-dose inhalers

scientific article published on 01 January 2000

Morphology of protein particles produced by spray freezing of concentrated solutions.

scientific article published on 18 August 2006

Mucoadhesive amorphous solid dispersions for sustained release of poorly water soluble drugs

scientific article published on 11 January 2017

Murine airway histology and intracellular uptake of inhaled amorphous itraconazole

scientific article published on 14 February 2007

Nebulization of mycophenolate mofetil inhalation suspension in rats: comparison with oral and pulmonary administration of Cellcept®.

scientific article published on 20 December 2012

Novel ultra-rapid freezing particle engineering process for enhancement of dissolution rates of poorly water-soluble drugs.

scientific article published on 26 July 2006

Personalized Medicine in Nasal Delivery: The Use of Patient-Specific Administration Parameters To Improve Nasal Drug Targeting Using 3D-Printed Nasal Replica Casts

scientific article published on 06 March 2018

Plasma deposited stability enhancement coating for amorphous ketoprofen

scientific article published on 15 December 2010

Preclinical evaluation of tacrolimus colloidal dispersion for inhalation

scientific article published on 03 December 2010

Predicting physical stability of ternary amorphous solid dispersions using specific mechanical energy in a hot melt extrusion process

scientific article published on 10 July 2018

Preparation of amorphous solid dispersions by rotary evaporation and KinetiSol Dispersing: approaches to enhance solubility of a poorly water-soluble gum extract.

scientific article published on 16 December 2013

Preparation of cyclosporine A nanoparticles by evaporative precipitation into aqueous solution

scientific article published on 01 August 2002

Processing thermally labile drugs by hot-melt extrusion: The lesson with gliclazide

scientific article published on 2 June 2017

Production of advanced solid dispersions for enhanced bioavailability of itraconazole using KinetiSol Dispersing.

scientific article published in September 2010

Properties of heat-humidity cured cellulose acetate phthalate free films.

scientific article published in October 2002

Recent developments in drug delivery to prolong allograft survival in lung transplant patients

scientific article published in March 2009

Single dose and multiple dose studies of itraconazole nanoparticles.

scientific article published on 3 March 2006

Solid dispersions of itraconazole and enteric polymers made by ultra-rapid freezing.

scientific article published on 26 November 2006

Solid lipid nanoparticle formulations of docetaxel prepared with high melting point triglycerides: in vitro and in vivo evaluation.

scientific article published on 12 March 2014

Solid-state NMR analysis of crystalline and amorphous Indomethacin: An experimental protocol for full resonance assignments

scientific article published on 06 November 2018

Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: organic solvent versus organic/aqueous co-solvent systems ⬇️

scientific article published on November 1, 2003

Spray freezing into liquid nitrogen for highly stable protein nanostructured microparticles

scientific article published on 01 November 2004

Spray freezing into liquid versus spray-freeze drying: influence of atomization on protein aggregation and biological activity

scientific article published on 26 September 2005

Stabilizer choice for rapid dissolving high potency itraconazole particles formed by evaporative precipitation into aqueous solution.

scientific article published in September 2005

Study of solubility of steroids in hydrofluoroalkane propellants

scientific article published on 01 December 1999

Supersaturation produces high bioavailability of amorphous danazol particles formed by evaporative precipitation into aqueous solution and spray freezing into liquid technologies.

scientific article published in June 2006

Sustained Release Drug Delivery Applications of Polyurethanes.

scientific article published on 9 May 2018

Targeted high lung concentrations of itraconazole using nebulized dispersions in a murine model.

scientific article published on 5 May 2006

Targeted intestinal delivery of supersaturated itraconazole for improved oral absorption.

scientific article

Templated open flocs of anisotropic particles for pulmonary delivery with pressurized metered dose inhalers.

scientific article published in July 2010

Templated open flocs of nanorods for enhanced pulmonary delivery with pressurized metered dose inhalers.

scientific article published on 29 August 2008

Ternary Amorphous Solid Dispersions Containing a High-Viscosity Polymer and Mesoporous Silica Enhance Dissolution Performance†

scientific article published on 08 December 2020

The COVID-19 Vaccine Race: Challenges and Opportunities in Vaccine Formulation

scientific article published on 05 August 2020

The impact of pulmonary diseases on the fate of inhaled medicines--a review

scientific article

Thermal Processing of PVP- and HPMC-Based Amorphous Solid Dispersions.

scientific article

Thermally Conductive Excipient Expands KinetiSol® Processing Capabilities

scientific article published on 11 November 2020

Turbidimetric measurement and prediction of dissolution rates of poorly soluble drug nanocrystals.

scientific article published on 17 November 2006

Uniform encapsulation of stable protein nanoparticles produced by spray freezing for the reduction of burst release

scientific article published on 01 January 2005

Use of Polyvinyl Alcohol as a Solubility Enhancing Polymer for Poorly Water-Soluble Drug Delivery (Part 2)

scientific article

Use of Polyvinyl Alcohol as a Solubility-Enhancing Polymer for Poorly Water Soluble Drug Delivery (Part 1).

scientific article

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