List of works - Ferenc Gallyas

A novel SOD-mimetic permeability transition inhibitor agent protects ischemic heart by inhibiting both apoptotic and necrotic cell death

scientific article published on 15 June 2006

A quinazoline-derivative compound with PARP inhibitory effect suppresses hypertension-induced vascular alterations in spontaneously hypertensive rats.

scientific article

Activation of metabotropic glutamate receptors does not alter the phosphorylation state of GluR1 AMPA receptor subunit at serine 845 in perirhinal cortical neurons.

scientific article

Alcohol-free red wine inhibits isoproterenol-induced cardiac remodeling in rats by the regulation of Akt1 and protein kinase C alpha/beta II.

scientific article published on 24 July 2008

Amiodarone's major metabolite, desethylamiodarone inhibits proliferation of B16-F10 melanoma cells and limits lung metastasis formation in an in vivo experimental model

scientific article published on 25 September 2020

Antioxidant and anti-inflammatory effects in RAW264.7 macrophages of malvidin, a major red wine polyphenol.

scientific article

BGP-15 - a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity

scientific journal article

BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases.

scientific article published on 14 February 2012

Coexistence of cholinergic, catecholaminergic, serotonergic, and glutamatergic neurotransmitter markers in mouse clonal hybrid neurons derived from the septal region

scientific article published on June 1, 1992

Critical role of bad phosphorylation by Akt in cytostatic resistance of human bladder cancer cells.

scientific article

Cyclic AMP influences protein synthesis in larval brains of Drosophila melanogaster.

scientific article published in January 1989

Cyclophilin D disruption attenuates lipopolysaccharide-induced inflammatory response in primary mouse macrophages

scientific article published on 23 January 2015

Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock.

scientific article published in April 2003

Effects of PACAP and preconditioning against ischemia/reperfusion-induced cardiomyocyte apoptosis in vitro.

scientific article published in April 2009

Effects of PACAP on mitochondrial apoptotic pathways and cytokine expression in rats subjected to renal ischemia/reperfusion

scientific journal article

Effects of PACAP on the circadian changes of signaling pathways in chicken pinealocytes.

scientific article published in July 2008

Effects of pituitary adenylate cyclase activating polypeptide (PACAP) on the PKA-Bad-14-3-3 signaling pathway in glutamate-induced retinal injury in neonatal rats

scientific journal article

Enhanced ADP-ribosylation and its diminution by lipoamide after ischemia-reperfusion in perfused rat heart

scientific article published on 01 November 1999

Facilitation of mitochondrial outer and inner membrane permeabilization and cell death in oxidative stress by a novel Bcl-2 homology 3 domain protein.

scientific article

Ferulaldehyde, a water-soluble degradation product of polyphenols, inhibits the lipopolysaccharide-induced inflammatory response in mice.

scientific article

Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells

scientific journal article

High-throughput screening of saliva for early detection of oral cancer: a pilot study.

scientific article

Hydroximic acid derivatives: pleiotropic HSP co-inducers restoring homeostasis and robustness.

scientific article published on January 2013

Hyperosmotic stress-induced apoptotic signaling pathways in chondrocytes

scientific article published on 23 February 2007

Induction of mitochondrial destabilization and necrotic cell death by apolar mitochondria-directed SOD mimetics.

scientific article published on February 2011

Induction of necrotic cell death and mitochondrial permeabilization by heme binding protein 2/SOUL

scientific article

Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death.

scientific article

Inhibition of cell death by a novel 16.2 kD heat shock protein predominantly via Hsp90 mediated lipid rafts stabilization and Akt activation pathway.

scientific article published on January 2007

Involvement of redox-signalling in endogenous hydrogen sulfide production

scientific article

Neurotransmitter synthesis by SN6 cell lines, a family of hybrid cell lines of embryonic septal origin.

scientific article

Neurotrophic effect of hematopoietic cytokines on cholinergic and other neurons in vitro.

scientific article published on June 1995

Novel mechanisms of sildenafil in pulmonary hypertension involving cytokines/chemokines, MAP kinases and Akt.

scientific article

PARP inhibition attenuates acute kidney allograft rejection by suppressing cell death pathways and activating PI-3K-Akt cascade

scientific article

PARP-1 inhibition-induced activation of PI-3-kinase-Akt pathway promotes resistance to taxol.

scientific article

PARP-inhibitor treatment prevents hypertension induced cardiac remodeling by favorable modulation of heat shock proteins, Akt-1/GSK-3β and several PKC isoforms

scientific article

PKA-Bad-14-3-3 and Akt-Bad-14-3-3 signaling pathways are involved in the protective effects of PACAP against ischemia/reperfusion-induced cardiomyocyte apoptosis.

scientific article published on 18 September 2007

Pivotal role of Akt activation in mitochondrial protection and cell survival by poly(ADP-ribose)polymerase-1 inhibition in oxidative stress.

scientific article published on 22 August 2005

Potentiation of paclitaxel-induced apoptosis by galectin-13 overexpression via activation of Ask-1-p38-MAP kinase and JNK/SAPK pathways and suppression of Akt and ERK1/2 activation in U-937 human macrophage cells.

scientific article

Prevalent role of Akt and ERK activation in cardioprotective effect of Ca(2+) channel- and beta-adrenergic receptor blockers.

scientific article published on 31 October 2008

Preventing apoptotic cell death by a novel small heat shock protein.

scientific article published on February 2007

Protection against chronic hypoperfusion-induced retinal neurodegeneration by PARP inhibition via activation of PI-3-kinase Akt pathway and suppression of JNK and p38 MAP kinases.

scientific article

Protective effect of amiodarone but not N-desethylamiodarone on postischemic hearts through the inhibition of mitochondrial permeability transition.

scientific article published on 11 September 2003

Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation ⬇️

scientific article published on May 14, 2012

Protective effects of pituitary adenylate cyclase activating polypeptide in endothelial cells against oxidative stress-induced apoptosis

scientific article published on 27 December 2006

Proteomic changes during experimental de- and remyelination in the corpus callosum

scientific article published on 09 April 2020

Regulation of MKP-1 expression and MAPK activation by PARP-1 in oxidative stress: a new mechanism for the cytoplasmic effect of PARP-1 activation.

scientific article published on 16 October 2010

Role of mitochondrial network stabilisation by a human small heat shock protein in tumour malignancy.

scientific article

Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: a critical role of MKP-1 ⬇️

scientific article published on September 30, 2010

TIP47 protects mitochondrial membrane integrity and inhibits oxidative-stress-induced cell death.

scientific article published on July 2010

TRAF6 is functional in inhibition of TLR4-mediated NF-κB activation by resveratrol.

scientific article published on 24 August 2012

The neuroprotective effects of PACAP in monosodium glutamate-induced retinal lesion involve inhibition of proapoptotic signaling pathways

scientific article published on 30 August 2006

Thymic Atrophy and Apoptosis of CD4+CD8+ Thymocytes in the Cuprizone Model of Multiple Sclerosis

scientific article published on 8 June 2015

List of works by Ferenc Gallyas

A novel SOD-mimetic permeability transition inhibitor agent protects ischemic heart by inhibiting both apoptotic and necrotic cell death

A quinazoline-derivative compound with PARP inhibitory effect suppresses hypertension-induced vascular alterations in spontaneously hypertensive rats.

Activation of metabotropic glutamate receptors does not alter the phosphorylation state of GluR1 AMPA receptor subunit at serine 845 in perirhinal cortical neurons.

Alcohol-free red wine inhibits isoproterenol-induced cardiac remodeling in rats by the regulation of Akt1 and protein kinase C alpha/beta II.

Amiodarone's major metabolite, desethylamiodarone inhibits proliferation of B16-F10 melanoma cells and limits lung metastasis formation in an in vivo experimental model

Antioxidant and anti-inflammatory effects in RAW264.7 macrophages of malvidin, a major red wine polyphenol.

BGP-15 - a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity

BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases.

Coexistence of cholinergic, catecholaminergic, serotonergic, and glutamatergic neurotransmitter markers in mouse clonal hybrid neurons derived from the septal region

Critical role of bad phosphorylation by Akt in cytostatic resistance of human bladder cancer cells.

Cyclic AMP influences protein synthesis in larval brains of Drosophila melanogaster.

Cyclophilin D disruption attenuates lipopolysaccharide-induced inflammatory response in primary mouse macrophages

Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock.

Effects of PACAP and preconditioning against ischemia/reperfusion-induced cardiomyocyte apoptosis in vitro.

Effects of PACAP on mitochondrial apoptotic pathways and cytokine expression in rats subjected to renal ischemia/reperfusion

Effects of PACAP on the circadian changes of signaling pathways in chicken pinealocytes.

Effects of pituitary adenylate cyclase activating polypeptide (PACAP) on the PKA-Bad-14-3-3 signaling pathway in glutamate-induced retinal injury in neonatal rats

Enhanced ADP-ribosylation and its diminution by lipoamide after ischemia-reperfusion in perfused rat heart

Facilitation of mitochondrial outer and inner membrane permeabilization and cell death in oxidative stress by a novel Bcl-2 homology 3 domain protein.

Ferulaldehyde, a water-soluble degradation product of polyphenols, inhibits the lipopolysaccharide-induced inflammatory response in mice.

Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells

High-throughput screening of saliva for early detection of oral cancer: a pilot study.

Hydroximic acid derivatives: pleiotropic HSP co-inducers restoring homeostasis and robustness.

Hyperosmotic stress-induced apoptotic signaling pathways in chondrocytes

Induction of mitochondrial destabilization and necrotic cell death by apolar mitochondria-directed SOD mimetics.

Induction of necrotic cell death and mitochondrial permeabilization by heme binding protein 2/SOUL

Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death.

Inhibition of cell death by a novel 16.2 kD heat shock protein predominantly via Hsp90 mediated lipid rafts stabilization and Akt activation pathway.

Involvement of redox-signalling in endogenous hydrogen sulfide production

Neurotransmitter synthesis by SN6 cell lines, a family of hybrid cell lines of embryonic septal origin.

Neurotrophic effect of hematopoietic cytokines on cholinergic and other neurons in vitro.

Novel mechanisms of sildenafil in pulmonary hypertension involving cytokines/chemokines, MAP kinases and Akt.

PARP inhibition attenuates acute kidney allograft rejection by suppressing cell death pathways and activating PI-3K-Akt cascade

PARP-1 inhibition-induced activation of PI-3-kinase-Akt pathway promotes resistance to taxol.

PARP-inhibitor treatment prevents hypertension induced cardiac remodeling by favorable modulation of heat shock proteins, Akt-1/GSK-3β and several PKC isoforms

PKA-Bad-14-3-3 and Akt-Bad-14-3-3 signaling pathways are involved in the protective effects of PACAP against ischemia/reperfusion-induced cardiomyocyte apoptosis.

Pivotal role of Akt activation in mitochondrial protection and cell survival by poly(ADP-ribose)polymerase-1 inhibition in oxidative stress.

Potentiation of paclitaxel-induced apoptosis by galectin-13 overexpression via activation of Ask-1-p38-MAP kinase and JNK/SAPK pathways and suppression of Akt and ERK1/2 activation in U-937 human macrophage cells.

Prevalent role of Akt and ERK activation in cardioprotective effect of Ca(2+) channel- and beta-adrenergic receptor blockers.

Preventing apoptotic cell death by a novel small heat shock protein.

Protection against chronic hypoperfusion-induced retinal neurodegeneration by PARP inhibition via activation of PI-3-kinase Akt pathway and suppression of JNK and p38 MAP kinases.

Protective effect of amiodarone but not N-desethylamiodarone on postischemic hearts through the inhibition of mitochondrial permeability transition.

Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation ⬇️

Protective effects of pituitary adenylate cyclase activating polypeptide in endothelial cells against oxidative stress-induced apoptosis

Proteomic changes during experimental de- and remyelination in the corpus callosum

Regulation of MKP-1 expression and MAPK activation by PARP-1 in oxidative stress: a new mechanism for the cytoplasmic effect of PARP-1 activation.

Role of mitochondrial network stabilisation by a human small heat shock protein in tumour malignancy.

Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: a critical role of MKP-1 ⬇️

TIP47 protects mitochondrial membrane integrity and inhibits oxidative-stress-induced cell death.

TRAF6 is functional in inhibition of TLR4-mediated NF-κB activation by resveratrol.

The neuroprotective effects of PACAP in monosodium glutamate-induced retinal lesion involve inhibition of proapoptotic signaling pathways

Thymic Atrophy and Apoptosis of CD4+CD8+ Thymocytes in the Cuprizone Model of Multiple Sclerosis