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List of works by Harry L T Mobley

A conserved PapB family member, TosR, regulates expression of the uropathogenic Escherichia coli RTX nonfimbrial adhesin TosA while conserved LuxR family members TosE and TosF suppress motility

scientific article

A novel approach for transcription factor analysis using SELEX with high-throughput sequencing (TFAST).

scientific article

A novel autotransporter of uropathogenic Proteus mirabilis is both a cytotoxin and an agglutinin

scientific article published on May 2008

A unique arabinose 5-phosphate isomerase found within a genomic island associated with the uropathogenicity of Escherichia coli CFT073.

scientific article

Acinetobacter baumannii Genes Required for Bacterial Survival during Bloodstream Infection.

scientific article

Acinetobacter baumannii Is Dependent on the Type II Secretion System and Its Substrate LipA for Lipid Utilization and In Vivo Fitness

scientific article published on 14 December 2015

Adhesion, invasion, and agglutination mediated by two trimeric autotransporters in the human uropathogen Proteus mirabilis

scientific article

An "omics" approach to uropathogenic Escherichia coli vaccinology

scientific article published on 14 September 2009

Anaerobic respiration using a complete oxidative TCA cycle drives multicellular swarming in Proteus mirabilis

scientific article

Arginine promotes Proteus mirabilis motility and fitness by contributing to conservation of the proton gradient and proton motive force

scientific article

Assessment of virulence of uropathogenic Escherichia coli type 1 fimbrial mutants in which the invertible element is phase-locked on or off

scientific article

Autotransporter genes pic and tsh are associated with Escherichia coli strains that cause acute pyelonephritis and are expressed during urinary tract infection

scientific article

Back to the metal age: battle for metals at the host-pathogen interface during urinary tract infection

scientific article

Bacterial proteomics and identification of potential vaccine targets

scientific article published in April 2010

Blocking yersiniabactin import attenuates extraintestinal pathogenic Escherichia coli in cystitis and pyelonephritis and represents a novel target to prevent urinary tract infection

scientific article

Capsule Production and Glucose Metabolism Dictate Fitness during Serratia marcescens Bacteremia

scientific article

Citrobacter freundii fitness during bloodstream infection

scientific article published in Scientific Reports

Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility

scientific article published on 28 March 2008

Conserved Residues and Motifs in the NixA Protein of Helicobacter pylori Are Critical for the High Affinity Transport of Nickel Ions ⬇️

scientific article published on 01 January 1998

Contribution of dppA to urease activity in Helicobacter pylori 26695.

scientific article published in October 2005

Coordinate expression of fimbriae in uropathogenic Escherichia coli

scientific article

CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII

scientific article published in 2018

Cross-talk between MarR-like transcription factors coordinates the regulation of motility in uropathogenic

scholarly article published by Harry L T Mobley in 2018

Cysteine Biosynthesis Controls Serratia marcescens Phospholipase Activity

scientific article

Defining genomic islands and uropathogen-specific genes in uropathogenic Escherichia coli

scientific article published on 9 March 2007

Determination of target sequence bound by PapX, repressor of bacterial motility, in flhD promoter using systematic evolution of ligands by exponential enrichment (SELEX) and high throughput sequencing

scientific article published on 28 October 2011

Development of a Vaccine against Escherichia coli Urinary Tract Infections

scientific article published on 31 December 2015

Development of an intranasal vaccine to prevent urinary tract infection by Proteus mirabilis

scientific article

Differential regulation of the Proteus mirabilis urease gene cluster by UreR and H-NS.

scientific article published in December 2003

Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments.

scientific article published on 15 November 2017

Dissemination and systemic colonization of uropathogenic Escherichia coli in a murine model of bacteremia

scientific article

Distinct Signature of Oxylipid Mediators of Inflammation during Infection and Asymptomatic Colonization by E. coli in the Urinary Bladder.

scientific article published on 27 December 2017

Draft genome sequences of five recent human uropathogenic Escherichia coli isolates

scientific article published on 02 July 2013

Editorial: Infection and immunity research at the University of Maryland, Baltimore

scientific article

Enzymatically active and inactive phosphodiesterases and diguanylate cyclases are involved in regulation of Motility or sessility in Escherichia coli CFT073

scientific article

Escherichia coli global gene expression in urine from women with urinary tract infection

scientific article

Escherichia coli isolates that carry vat, fyuA, chuA, and yfcV efficiently colonize the urinary tract

scientific article

Evaluation of CpxRA as a Therapeutic Target for Uropathogenic Escherichia coli Infections

scientific article

Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract

scholarly article

FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections

scientific article

Ferric Citrate Uptake Is a Virulence Factor in Uropathogenic Escherichia coli

scientific article published in 2022

Fimbrial profiles predict virulence of uropathogenic Escherichia coli strains: contribution of ygi and yad fimbriae

scientific article published on 12 September 2011

Fitness of Escherichia coli during urinary tract infection requires gluconeogenesis and the TCA cycle

scientific article

Genetically diverse uropathogenic adopt a common transcriptional program in patients with UTIs

scientific article published on 21 October 2019

Genome-Wide Identification of Klebsiella pneumoniae Fitness Genes during Lung Infection

scientific article published on 9 June 2015

Genome-wide detection of fitness genes in uropathogenic Escherichia coli during systemic infection

scientific article

Genome-wide transposon mutagenesis of Proteus mirabilis: Essential genes, fitness factors for catheter-associated urinary tract infection, and the impact of polymicrobial infection on fitness requirements

scientific article

Genomic characterization of asymptomatic Escherichia coli isolated from the neobladder ⬇️

scientific article published on January 20, 2011

Genomic islands of uropathogenic Escherichia coli contribute to virulence

scientific article published on 27 March 2009

Green fluorescent protein urea sensors. Uropathogenic Proteus mirabilis

scientific article

Haem acquisition is facilitated by a novel receptor Hma and required by uropathogenic Escherichia coli for kidney infection

scientific article published on 30 October 2008

Helicobacter pylori ABC transporter: effect of allelic exchange mutagenesis on urease activity ⬇️

scientific article published on September 1, 1997

Helicobacter pylori Growth and Urease Detection in the Chemically Defined Medium Ham's F-12 Nutrient Mixture ⬇️

scientific article published on November 1, 2001

Helicobacter pylori HP1512 is a nickel-responsive NikR-regulated outer membrane protein

scientific article

Helicobacter pylori nickel‐transport gene nixA: synthesis of catalytically active urease in Escherichia coli independent of growth conditions ⬇️

scientific article published on April 1, 1995

Helicobacter pyloriarginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival ⬇️

scientific article published on November 20, 2001

Homology among arsenate resistance determinants of R factors in Escherichia coli ⬇️

scientific article published on February 1, 1984

Host Characteristics and Bacterial Traits Predict Experimental Virulence for Escherichia coli Bloodstream Isolates From Patients With Urosepsis

scientific article published on 6 June 2015

Host-pathogen interactions in urinary tract infection

scientific article published on 20 July 2010

Host-specific induction of Escherichia coli fitness genes during human urinary tract infection

scientific article

How Often Do Clinically Diagnosed Catheter-Associated Urinary Tract Infections in Nursing Homes Meet Standardized Criteria?

scientific article published on 14 November 2016

Identification of MrpI as the sole recombinase that regulates the phase variation of MR/P fimbria, a bladder colonization factor of uropathogenic Proteus mirabilis

scientific article

Identification of a modular pathogenicity island that is widespread among urease-producing uropathogens and shares features with a diverse group of mobile elements

scientific article published on 17 August 2009

Identification of in vivo-induced antigens including an RTX family exoprotein required for uropathogenic Escherichia coli virulence

scientific article

Identification of uropathogenic Escherichia coli surface proteins by shotgun proteomics

scientific article published on 06 May 2009

Identification of virulence determinants in uropathogenic Proteus mirabilis using signature-tagged mutagenesis

scientific article published in September 2008

Immunization with the yersiniabactin receptor, FyuA, protects against pyelonephritis in a murine model of urinary tract infection

scientific article published on 24 June 2013

In vivo behavior of a Helicobacter pylori SS1 nixA mutant with reduced urease activity

scientific article

Increased incidence of urolithiasis and bacteremia during Proteus mirabilis and Providencia stuartii coinfection due to synergistic induction of urease activity

scientific article

Inhibitors of TonB function identified by a high-throughput screen for inhibitors of iron acquisition in uropathogenic Escherichia coli CFT073.

scientific article published on 25 February 2014

Initiation of swarming motility by Proteus mirabilis occurs in response to specific cues present in urine and requires excess L-glutamine

scientific article published on 11 January 2013

Involvement of mismatch repair in the reciprocal control of motility and adherence of uropathogenic Escherichia coli

scientific article

Kinetics of uropathogenic Escherichia coli metapopulation movement during urinary tract infection

scientific article published on 7 February 2012

Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women with urinary tract infection

scientific article

Mannose-resistant Proteus-like fimbriae are produced by most Proteus mirabilis strains infecting the urinary tract, dictate the in vivo localization of bacteria, and contribute to biofilm formation

scientific article

Measuring Escherichia coli Gene Expression during Human Urinary Tract Infections

scientific article published on 15 January 2016

Merging mythology and morphology: the multifaceted lifestyle of Proteus mirabilis ⬇️

scientific article published on October 8, 2012

Metabolism and Fitness of Urinary Tract Pathogens

scientific article published in June 2015

MrpH, a new class of metal-binding adhesin, requires zinc to mediate biofilm formation

scientific article published on 11 August 2020

Mucosal immunization with iron receptor antigens protects against urinary tract infection

scientific article published on 18 September 2009

Multiple genes repress motility in uropathogenic Escherichia coli constitutively expressing type 1 fimbriae

scientific article

Nutritional requirements and antibiotic resistance patterns of Helicobacter species in chemically defined media

scientific article

Outer membrane antigens of the uropathogen Proteus mirabilis recognized by the humoral response during experimental murine urinary tract infection

scientific article published on 14 July 2008

PapX, a P fimbrial operon-encoded inhibitor of motility in uropathogenic Escherichia coli

scientific article published on 18 August 2008

Pathogenesis of Proteus mirabilis Infection

scientific article published in February 2018

Phenotypic Assessment of Clinical Escherichia coli Isolates as an Indicator for Uropathogenic Potential

scientific article published in 2022

Preferential use of central metabolism in vivo reveals a nutritional basis for polymicrobial infection

scientific article

Presence of putative repeat-in-toxin gene tosA in Escherichia coli predicts successful colonization of the urinary tract

scientific article

Preventing urinary tract infection: progress toward an effective Escherichia coli vaccine

scientific article

Protease activity, secretion, cell entry, cytotoxicity, and cellular targets of secreted autotransporter toxin of uropathogenic Escherichia coli

scientific article

Proteobactin and a yersiniabactin-related siderophore mediate iron acquisition in Proteus mirabilis

scientific article

Proteus mirabilis amino acid deaminase: cloning, nucleotide sequence, and characterization of aad ⬇️

scientific article published on October 1, 1995

Proteus mirabilis genes that contribute to pathogenesis of urinary tract infection: identification of 25 signature-tagged mutants attenuated at least 100-fold

scientific article published on May 2004

Proteus mirabilis urease: transcriptional regulation by UreR ⬇️

scientific article published on January 1, 1993

Quantitative profile of the uropathogenic Escherichia coli outer membrane proteome during growth in human urine

scientific article

Rapid Growth of Uropathogenic Escherichia coli during Human Urinary Tract Infection

scientific article published on 6 March 2018

Redundancy and specificity of Escherichia coli iron acquisition systems during urinary tract infection

scientific article

Regulation of Expression of Uropathogenic Escherichia coli Nonfimbrial Adhesin TosA by PapB Homolog TosR in Conjunction with H-NS and Lrp

scientific article published on 11 January 2016

Repression of motility during fimbrial expression: identification of 14 mrpJ gene paralogues in Proteus mirabilis

scientific article published on July 2008

Role of ethanolamine utilization genes in host colonization during urinary tract infection.

scientific article published on 11 December 2017

Role of motility in the colonization of uropathogenic Escherichia coli in the urinary tract

scientific article

Role of phase variation of type 1 fimbriae in a uropathogenic Escherichia coli cystitis isolate during urinary tract infection

scientific article

Role of the K2 capsule in Escherichia coli urinary tract infection and serum resistance

scientific article published on June 2009

Sat, the secreted autotransporter toxin of uropathogenic Escherichia coli, is a vacuolating cytotoxin for bladder and kidney epithelial cells

scientific article

Self-transmissibility of the integrative and conjugative element ICEPm1 between clinical isolates requires a functional integrase, relaxase, and type IV secretion system

scientific article

Siderophore vaccine conjugates protect against uropathogenic Escherichia coli urinary tract infection

scientific article

Signature-tagged mutagenesis and co-infection studies demonstrate the importance of P fimbriae in a murine model of urinary tract infection

scientific article

SslE elicits functional antibodies that impair in vitro mucinase activity and in vivo colonization by both intestinal and extraintestinal Escherichia coli strains

scientific article (publication date: May 2014)

Subtle variation within conserved effector operon gene products contributes to T6SS-mediated killing and immunity.

scientific article published on 20 November 2017

Targeting the Type II Secretion System: Development, Optimization, and Validation of a High-Throughput Screen for the Identification of Small Molecule Inhibitors

scientific article

The Helicobacter pylori flbA flagellar biosynthesis and regulatory gene is required for motility and virulence and modulates urease of H. pylori and Proteus mirabilis

scientific article

The IrgA homologue adhesin Iha is an Escherichia coli virulence factor in murine urinary tract infection

scientific article

The Pathogenic Potential of Proteus mirabilis Is Enhanced by Other Uropathogens during Polymicrobial Urinary Tract Infection.

scientific article

The UDP-GalNAcA biosynthesis genes gna-gne2 are required to maintain cell envelope integrity and in vivo fitness in multi-drug resistant Acinetobacter baumannii

scientific article published on 19 November 2019

The Versatile Type VI Secretion System

scientific article published on April 2016

The broadly conserved regulator PhoP links pathogen virulence and membrane potential in Escherichia coli

scientific article

The high-affinity phosphate transporter Pst is a virulence factor for Proteus mirabilis during complicated urinary tract infection.

scientific article published on 8 January 2008

The innate immune response to uropathogenic Escherichia coli involves IL-17A in a murine model of urinary tract infection

scientific article

The lytic transglycosylase MltB connects membrane homeostasis and in vivo fitness of Acinetobacter baumannii

scholarly article by Sébastien Crépin published in September 2018

The multifunctional protein YdiV represses P fimbria-mediated adherence in uropathogenic Escherichia coli

scientific article published on 10 May 2013

TnseqDiff: identification of conditionally essential genes in transposon sequencing studies

scientific article

TosR-Mediated Regulation of Adhesins and Biofilm Formation in Uropathogenic Escherichia coli.

scientific article published on 16 May 2018

Transcriptome of Proteus mirabilis in the murine urinary tract: virulence and nitrogen assimilation gene expression

scientific article

Transcriptome of swarming Proteus mirabilis

scientific article

Transcriptome of uropathogenic Escherichia coli during urinary tract infection

scientific article

Twin arginine translocation, ammonia incorporation, and polyamine biosynthesis are crucial for Proteus mirabilis fitness during bloodstream infection

scientific article published on 22 April 2019

UreR, the transcriptional activator of the Proteus mirabilis urease gene cluster, is required for urease activity and virulence in experimental urinary tract infections

scientific article

Urease of enterohemorrhagic Escherichia coli: evidence for regulation by fur and a trans-acting factor

scientific article

Uropathogenic Escherichia coli Suppresses the host inflammatory response via pathogenicity island genes sisA and sisB.

scientific article published on 21 September 2009

Uropathogenic Escherichia coli outer membrane antigens expressed during urinary tract infection

scientific article

Uropathogenic Escherichia coli strains generally lack functional Trg and Tap chemoreceptors found in the majority of E. coli strains strictly residing in the gut.

scientific article

Uropathogenic Escherichia coli.

scientific article

VO: Vaccine Ontology

VO: Vaccine Ontology

VO: Vaccine Ontology

VO: Vaccine Ontology

Vaccination with proteus toxic agglutinin, a hemolysin-independent cytotoxin in vivo, protects against Proteus mirabilis urinary tract infection

scientific article

Vaccines for Proteus mirabilis in urinary tract infection

scientific article

Vaxign: the first web-based vaccine design program for reverse vaccinology and applications for vaccine development

scientific article

Virulence and Fitness Determinants of Uropathogenic Escherichia coli

scientific article

Visualization of Proteus mirabilis morphotypes in the urinary tract: the elongated swarmer cell is rarely observed in ascending urinary tract infection

scientific article

Visualization of Proteus mirabilis within the matrix of urease-induced bladder stones during experimental urinary tract infection

scientific article

Waging war against uropathogenic Escherichia coli: winning back the urinary tract

scientific article

Wounds, functional disability, and indwelling devices are associated with cocolonization by methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci in southeast Michigan

scientific article published on December 2011

Zinc uptake contributes to motility and provides a competitive advantage to Proteus mirabilis during experimental urinary tract infection

scientific article

complex interplay between type 1 fimbrial expression and flagellum-mediated motility of uropathogenic Escherichia coli

scientific article

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