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List of works by François Diederich

1,2,3-triazoles as conjugative pi-linkers in push-pull chromophores: importance of substituent positioning on intramolecular charge-transfer

scientific article published on 27 June 2008

1,2-Di(phenylethynyl)ethenes with axially chiral, 2,2′-bridged 1,1′-binaphthyl substituents: potent cholesteric liquid-crystal inducers

scientific article published on October 21, 2012

1,3-Diethynylallenes (DEAs): enantioselective synthesis, absolute configuration, and chiral induction in 1,1,4,4-tetracyanobuta-1,3-dienes (TCBDs).

scientific article published in January 2008

1,3-Diethynylallenes: Carbon-Rich Modules for Three-Dimensional Acetylenic Scaffolding

1,3-Diethynylallenes: New Modules for Three-Dimensional Acetylenic Scaffolding

scientific article published on 01 June 2001

125 Jahre Chemie im Spiegel der “Angewandten”

125 Years of Chemistry in the Mirror of “Angewandte”

scientific article published on February 18, 2013

2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design

scientific article published on 06 April 2018

25 Years Full of Chemical Discovery

scientific article published on 01 January 2011

40 years of supramolecular chemistry

scientific article published on 01 January 2007

6,6-Dicyanopentafulvenes: electronic structure and regioselectivity in [2 + 2] cycloaddition-retroelectrocyclization reactions

scientific article published on 19 October 2012

6,6-Dicyanopentafulvenes: teaching an old dog new tricks

scientific article published on 13 October 2014

61,61-Bis(trimethylsilylbutadiynyl)-1,2-dihydro-1,2-methanofullerene[60]: Crystal Structure at 100 K and Electrochemical Conversion to a Conducting Polymer

A Four-Step Synthesis of Substituted 5,11-Dicyano-6,12-diaryltetracenes with Enhanced Stability and High Fluorescence Emission.

scientific article published on 15 November 2017

A Mild, Thermal Pentafulvene-to-Benzene Rearrangement

scientific article published on 25 July 2013

A New Class of Inhibitors for the Metalloprotease Neprilysin Based on a Central Imidazole Scaffold

scholarly article by Stefan Sahli et al published April 2005 in Helvetica Chimica Acta

A Novel Three-Way Chromophoric Molecular Switch: pH and Light Controllable Switching Cycles

scientific article published on 01 March 1999

A Three-Step Synthesis of Tetrasubstituted NH-Pyrroles

scientific article published on 26 April 2016

A Weak Attractive Interaction between Organic Fluorine and an Amide Group

article

A fluorine scan at the catalytic center of thrombin: C--F, C--OH, and C--OMe bioisosterism and fluorine effects on pKa and log D values

scientific article published in June 2006

A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pKa and binding affinity and evidence for intermolecular C-F...CN interactions

scientific article published on 14 April 2004

A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions

scientific article

A new class of organic donor-acceptor molecules with large third-order optical nonlinearities

scientific article

A new pyridyl-substituted methanofullerene derivative. Photophysics, electrochemistry and self-assembly with zinc(II) meso-tetraphenylporphyrin (ZnTPP)

article by Nicola Armaroli et al published 1999 in New Journal of Chemistry

A new water-soluble macrocyclic host of the cyclophane type: host-guest complexation with aromatic guests in aqueous solution and acceleration of the transport of arenes through an aqueous phase

scientific article published in 1984

A novel reaction of 7,7,8,8-tetracyanoquinodimethane (TCNQ): charge-transfer chromophores by [2 + 2] cycloaddition with alkynes

scientific article published on 24 October 2007

A shape-persistent alleno-acetylenic macrocycle with a modifiable periphery: synthesis, chiroptical properties and H-bond-driven self-assembly into a homochiral columnar structure

scientific article published on July 23, 2013

A supramolecular approach for the formation of fullerene–phthalocyanine dyads

A supramolecular multiposition rotary device

scientific article published in January 2007

Absolute configuration of chiral fullerenes and covalent derivatives from their calculated circular dichroism spectra

Acetylene-derived strong organic acceptors for planar and nonplanar push-pull chromophores

scientific article

Acetylenic scaffolding on solid support: poly(triacetylene)-derived oligomers by Sonogashira and Cadiot-Chodkiewicz-type cross-coupling reactions

scientific article published on 01 January 2003

Acetylenic tetrathiafulvalene-dicyanovinyl donor-acceptor chromophores

scientific article published on 6 July 2009

Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of PKA and a PKB Mimic

scientific article

Adsorbate-Induced Modification of the Confining Barriers in a Quantum Box Array.

scientific article published on 22 December 2017

Adsorption and Dynamics of Long-Range Interacting Fullerenes in a Flexible, Two-Dimensional, Nanoporous Porphyrin Network

scientific article published on 21 June 2006

All-carbon scaffolds by rational design

scientific article published on February 2010

All-optical switching with 1-ps response time in a DDMEBT enabled silicon grating coupler/resonator hybrid device.

scientific article published in October 2014

Allenes in Molecular Materials

scientific article published on February 3, 2012

Alleno-Acetylenic Cage (AAC) Receptors: Chiroptical Switching and Enantioselective Complexation of trans-1,2-Dimethylcyclohexane in a Diaxial Conformation.

scientific article

Amphiphilic Dendrimers: Novel Self‐Assembling Vectors for Efficient Gene Delivery

scientific article published on April 4, 2003

Amplification of Chirality in Monodisperse, Enantiopure Alleno-Acetylenic Oligomers

scientific article published on 01 March 2010

An Immucillin-Based Transition-State-Analogous Inhibitor of tRNA-Guanine Transglycosylase (TGT).

scientific article published on 31 March 2016

An amphiphilic graft copolymer-based nanoparticle platform for reduction-responsive anticancer and antimalarial drug delivery

scientific article published on 25 July 2016

An enantiomerically pure alleno-acetylenic macrocycle: synthesis and rationalization of its outstanding chiroptical response.

scientific article

An insight into the aromaticity of fullerene anions: experimental evidence for diamagnetic ring currents in the five-membered rings of C(60)(6-) and C(70)(6-)

scientific article published on 01 May 2002

Anilino-Substituted Multicyanobuta-1,3-diene Electron Acceptors: TICT Molecules with Accessible Conical Intersections

Anilino-Substituted Multicyanobuta-1,3-diene Electron Acceptors: TICT Molecules with Accessible Conical Intersections

Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures

scientific article

Are we refereeing ourselves to death? The peer-review system at its limit

scientific article

Aromatic Rings in Chemical and Biological Recognition: Energetics and Structures

scientific article published on April 28, 2011

Aromaticity and Electron Affinity of Carbok-[3]radialenes, k = 0, 1, 2

Aromaticity and electron affinity of Carbo(k)-[3]radialenes, k=0, 1, 2.

scientific article published in October 2003

Aryl Bis-Sulfonamide Inhibitors of IspF fromArabidopsis thalianaandPlasmodium falciparum

scholarly article by Jonas Thelemann et al published 5 October 2015 in ChemMedChem

Aryl bis-sulfonamides bind to the active site of a homotrimeric isoprenoid biosynthesis enzyme IspF and extract the essential divalent metal cation cofactor

scientific article published on 18 June 2018

Benzenoidversus Annulenoid Aromaticity: Synthesis and Properties of Kekulene

scholarly article by François Diederich & Heinz A. Staab published May 1978 in Angewandte Chemie International Edition

Betraying the parasite's redox system: diaryl sulfide-based inhibitors of trypanothione reductase: subversive substrates and antitrypanosomal properties

scientific article

Beyond C60: the higher fullerenes

article

Beyond affinity: enthalpy-entropy factorization unravels complexity of a flat structure-activity relationship for inhibition of a tRNA-modifying enzyme

scientific article

Binding to large enzyme pockets: small-molecule inhibitors of trypanothione reductase

scientific article

Biological Evaluation and X-ray Co-crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma.

scientific article published on 6 April 2018

Bisubstrate Inhibitors of the Enzyme Catechol O-Methyltransferase (COMT): Efficient Inhibition Despite the Lack of a Nitro Group

scholarly article by Ralph Paulini published in September 2004

Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity

scientific article published in January 2003

Bisubstrate inhibitors of catechol O-methyltransferase (COMT): the crucial role of the ribose structural unit for inhibitor binding affinity

scientific article published in March 2006

Calculation of binding free energies of inhibitors to plasmepsin II.

scientific article published on 12 April 2011

Carbon scaffolding: building acetylenic all-carbon and carbon-rich compounds

scientific article published in Nature

Cascade Carbopalladation Reaction between Alkynes and gem-Dibromoolefins: Facile Access to Monoannelated Pentalenes

scientific article published on July 31, 2012

Cascade Pericyclic Reactions of Alleno‐Acetylenes: Facile Access to Highly Substituted Cyclobutene, Dendralene, Pentalene, and Indene Skeletons

scientific article published on November 11, 2011

Catechol-O-methyltransferase in complex with substituted 3′-deoxyribose bisubstrate inhibitors

scientific article published on February 14, 2012

Cation-pi interactions at the active site of factor Xa: dramatic enhancement upon stepwise N-alkylation of ammonium ions

scientific article

Chalcogen Bonding "2S-2N Squares" versus Competing Interactions: Exploring the Recognition Properties of Sulfur

scientific article published on 11 December 2018

Charge-Transfer Salts of 6,6-Dicyanopentafulvenes: From Topology to Charge Separation in Solution

scientific article published on 10 August 2018

Charge-transfer chromophores by cycloaddition-retro-electrocyclization: multivalent systems and cascade reactions

scientific article published on 01 January 2007

Charge-transfer interactions in face-to-face porphyrin-fullerene systems: solvent-dependent luminescence in the infrared spectral region

Chasing protons: how isothermal titration calorimetry, mutagenesis, and pKa calculations trace the locus of charge in ligand binding to a tRNA-binding enzyme

scientific article

ChemInform Abstract: Cascade Carbopalladation Reaction Between Alkynes and gem-Dibromoolefins: Facile Access to Monoanellated Pentalenes

ChemInform Abstract: Post-Cycloaddition-Retroelectrocyclization Transformations of Polycyanobutadienes

ChemInform Abstract: Unprecedented Thermal Rearrangement of Push-Pull-Chromophore-[60]Fullerene Conjugates: Formation of Chiral 1,2,9,12-Tetrakis-Adducts (IV)

Chemistry of C84: Separation of Three Constitutional Isomers and Optical Resolution ofD2-C84 by Using the “Bingel-Retro-Bingel” Strategy

scientific article published on 01 June 1999

Chinon-basierte redoxaktive Resorcin[4]aren-Cavitanden

Chiral induction from allenes into twisted 1,1,4,4-tetracyanobuta-1,3-dienes (TCBDs): conformational assignment by circular dichroism spectroscopy

scientific article

Chirality Transfer in 1D Self-Assemblies: Influence of H-Bonding vs Metal Coordination between Dicyano[7]helicene Enantiomers

scientific article published on 3 October 2013

Chiroptical Detection of Nonchromophoric, Achiral Guests by Enantiopure Alleno-Acetylenic Helicages

scientific article published on 10 November 2014

Cleft-Type Diamidinium Receptors for Dicarboxylate Binding in Protic Solvents

Conformational Aspects in the Design of Inhibitors for Serine Hydroxymethyltransferase (SHMT): Biphenyl, Aryl Sulfonamide, and Aryl Sulfone Motifs.

scientific article

Conformational Behavior of Pyrazine-Bridged and Mixed-Bridged Cavitands: A General Model for Solvent Effects on Thermal “Vase–Kite” Switching

scientific article published on 01 June 2006

Conjugated oligoenynes based on the diethynylethene unit

scientific article published in May 2005

Container molecules with portals: Reversibly switchable cycloalkane complexation

scientific article published on 01 January 2007

Controlling the Dimensionality and Structure of Supramolecular Porphyrin Assemblies by their Functional Substituents: Dimers, Chains, and Close-Packed 2D Assemblies

scientific article published on 12 October 2012

Corrigendum: Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of PKA and a PKB Mimic

scientific article published on 02 July 2020

Cover Picture: Aromaticity and Electron Affinity of Carbok-[3]radialenes,k=0, 1, 2 (Chem. Eur. J. 20/2003)

Cryogenic 35GHz pulse ENDOR probehead accommodating large sample sizes: Performance and applications.

scientific article

Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT

scientific article

Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding

scientific article

Crystallographic study of inhibitors of tRNA-guanine transglycosylase suggests a new structure-based pharmacophore for virtual screening

scientific article published in April 2004

Cyanobuta-1,3-dienes as novel electron acceptors for photoactive multicomponent systems

scientific article published on 12 December 2013

Cyanoethynylethenes: a class of powerful electron acceptors for molecular scaffolding

scientific article published on 01 August 2002

Cycloalkane and Alicyclic Heterocycle Complexation by New Switchable Resorcin[4]arene-Based Container Molecules: NMR and ITC Binding Studies

scientific article published on 21 September 2011

Cycloarenes, a New Class of Aromatic Compounds, I. Synthesis of Kekulene

De Novo design, synthesis, and in vitro evaluation of a new class of nonpeptidic inhibitors of the malarial enzyme plasmepsin II.

scientific article published in November 2002

De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: a dramatic sulfur effect on binding affinity

scientific article

Dendritic metalloporphyrins with a distal H-bond donor as mimics of haemoglobin

scientific article published on 01 April 2003

Dendroclefts: Optically Active Dendritic Receptors for the Selective Recognition and Chiroptical Sensing of Monosaccharide Guests

scholarly article by David K. Smith et al published 4 August 1999 in Helvetica Chimica Acta

Dendronised block copolymers as potential vectors for gene transfection

scientific article published on 7 April 2008

Deorphaning pyrrolopyrazines as potent multi-target antimalarial agents

scientific article published on 4 June 2014

Design and Synthesis of Aviram-Ratner-Type Dyads and Rectification Studies in Langmuir-Blodgett (LB) Films

scientific article published on 01 July 2016

Determination of End-to-End Distances in a Series of TEMPO Diradicals of up to 2.8 nm Length with a New Four-Pulse Double Electron Electron Resonance Experiment

scientific article published on 01 November 1998

Development of redox-switchable resorcin[4]arene cavitands

scientific article published on 9 May 2014

Diaryl sulfide-based inhibitors of trypanothione reductase: inhibition potency, revised binding mode and antiprotozoal activities

scientific article

Die Chemie von C84: Trennung von drei Konstitutionsisomeren des Fullerens C84 und der Enantiomere vonD2-C84 durch die „Bingel-Retro-Bingel”-Strategie

Direct evidence for a hydrogen bond to bound dioxygen in a myoglobin/hemoglobin model system and in cobalt myoglobin by pulse-EPR spectroscopy

scientific article published on 01 January 2008

Directed Rotations of Single Porphyrin Molecules Controlled by Localized Force Spectroscopy

scientific article published on 07 June 2012

Dispersion and Halogen-Bonding Interactions: Binding of the Axial Conformers of Monohalo- and (±)-trans-1,2-Dihalocyclohexanes in Enantiopure Alleno-Acetylenic Cages.

scientific article published on 15 August 2017

Donor-acceptor (D-A)-substituted polyyne chromophores: modulation of their optoelectronic properties by varying the length of the acetylene spacer.

scientific article

Donor-substituted 1,1,4,4-tetracyanobutadienes (TCBDS): new chromophores with efficient intramolecular charge-transfer interactions by atom-economic synthesis

scientific article published in February 2006

Donor-substituted cyanoethynylethenes: pi-conjugation and band-gap tuning in strong charge-transfer chromophores

scientific article published on 01 May 2005

Donor-substituted cyanoethynylethenes: powerful chromophores for opto-electronic applications

scientific article published in June 2003

Donor-substituted diphenylacetylene derivatives act as electron donors and acceptors

scientific article published on 13 June 2011

Donor-substituted octacyano[4]dendralenes: investigation of π-electron delocalization in their radical ions.

scientific article published on 27 July 2012

Donor-substituted peralkynylated "radiaannulenes": novel all-carbon macrocycles with an intense intramolecular charge-transfer

scientific article published in July 2003

Effective cholesteric liquid crystal inducers based on axially chiral alleno-acetylenes

scholarly article in RSC Advances, vol. 3 no. 45, 2013

Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers

scientific article published on 26 January 2006

Effects of the dendrimer cage on O2 binding of dendritic cobalt(II) porphyrins

scientific article

Efficient Stacking on Protein Amide Fragments

scientific article published on January 25, 2013

Eine milde thermische Pentafulven-Benzol-Umlagerung

Electrochemistry of Mono- through Hexakis-adducts of C60

article by Corinne Boudon et al published 9 August 1995 in Helvetica Chimica Acta

Electronic Structures and Chiroptical Properties of Post-functionalized Helicene Quinones

scientific article

Electronically Connected [n]Helicenes: Synthesis and Chiroptical Properties of Enantiomerically Pure (E)-1,2-Di([6]helicen-2-yl)ethenes

Enantiomerically Pure Alleno-Acetylenic Macrocycles: Synthesis, Solid-State Structures, Chiroptical Properties, and Electron Localization Function Analysis

scientific article published on 01 August 2010

Enantiopure Alleno-Acetylenic Helicages Containing Multiple Binding Sites

scientific article published on 10 October 2016

Enantiopure laterally functionalized alleno-acetylenic macrocycles: synthesis, chiroptical properties, and self-assembly in aqueous media

scientific article published on 24 October 2014

Enantiopure, Monodisperse Alleno‐acetylenic Cyclooligomers: Effect of Symmetry and Conformational Flexibility on the Chiroptical Properties of Carbon‐Rich Compounds

scientific article published on February 25, 2011

Enthalpically driven cyclophane-arene inclusion complexation: solvent-dependent calorimetric studies

scientific article published in 1991

Evaluation of hydrogen-bond acceptors for redox-switchable resorcin[4]arene cavitands

scientific article published on 25 February 2014

Evidence for the Formation of Singly Bonded Dimers During the Reductive Electrochemistry of Methanofullerenes

scientific article published on October 6, 2003

Exceptional Redox and Photophysical Properties of a Triply Fused Diporphyrin–C60 Conjugate: Novel Scaffolds for Multicharge Storage in Molecular Scale Electronics

scientific article published on 01 October 2003

Expanded cubane: synthesis of a cage compound with a C56 core by acetylenic scaffolding and gas-phase transformations into fullerenes

scientific article published in November 2002

Expanding the Chemical Structure Space of Opto-Electronic Molecular Materials: Unprecedented Push–Pull Chromophores by Reaction of a Donor-Substituted Tetracyanofulvene with Electron-Rich Alkynes

scientific article published on February 21, 2013

Expanding the chemical space for push-pull chromophores by non-concerted [2+2] and [4+2] cycloadditions: access to a highly functionalised 6,6-dicyanopentafulvene with an intense, low-energy charge-transfer band

scientific article published on 11 March 2011

Experimental and computational study of BODIPY dye-labeled cavitand dynamics

scientific article

Exploring the Strength of the H-Bond in Synthetic Models for Heme Proteins: The Importance of the N-H Acidity of the Distal Base

scientific article

Exploring the flap pocket of the antimalarial target plasmepsin II: the "55 % rule" applied to enzymes

scientific article published in February 2008

FRET Studies on a Series of BODIPY‐Dye‐Labeled Switchable Resorcin[4]arene Cavitands

scientific article published on 01 November 2010

First asymmetric synthesis of a differentially silyl-protected tris(alkynyl)methyl methyl ether

scientific article published on 20 February 2006

Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy.

scientific article

Fluorine Scan of Inhibitors of the Cysteine Protease Human Cathepsin L: Dipolar and Quadrupolar Effects in the π-Stacking of Fluorinated Phenyl Rings on Peptide Amide Bonds

scientific article published on 20 April 2016

Fluorine in pharmaceuticals: looking beyond intuition

scientific article

Fluorine interactions at the thrombin active site: protein backbone fragments H-C(alpha)-C=O comprise a favorable C-F environment and interactions of C-F with electrophiles

scientific article

Fragment Screening Hit Draws Attention to a Novel Transient Pocket Adjacent to the Recognition Site of the tRNA-Modifying Enzyme TGT

scientific article published on 09 June 2020

Free enthalpies of replacing water molecules in protein binding pockets

scientific article published on 18 December 2012

From homoconjugated push-pull chromophores to donor-acceptor-substituted spiro systems by thermal rearrangement

scientific article published on 2 January 2014

From lin-benzoguanines to lin-benzohypoxanthines as ligands for Zymomonas mobilis tRNA-guanine transglycosylase: replacement of protein-ligand hydrogen bonding by importing water clusters

scientific article

Fullerene Anions of Different Sizes and Shapes: A13C NMR and Density-Functional Study

Fullerene-Acetylene Hybrids: On the Way to Synthetic Molecular Carbon Allotropes

Fullerene-acetylene hybrids: Towards a novel class of molecular carbon allotropes

Geometrically precisely defined multinanometer expansion/contraction motions in a resorcin[4]arene cavitand based molecular switch

scientific article published on 01 July 2005

H-Bonded complexes of adenine with Rebek imide receptors are stabilised by cation-pi interactions and destabilised by stacking with perfluoroaromatics

scientific article published on 23 January 2004

Halogen Bonding of (Iodoethynyl)benzene Derivatives in Solution

scientific article published on 29 August 2014

Halogen bonding at the active sites of human cathepsin L and MEK1 kinase: efficient interactions in different environments

scientific article published on September 6, 2011

Halogen bonding molecular capsules

scientific article

Halogen-Bonded Supramolecular Capsules in the Solid State, in Solution, and in the Gas Phase

scientific article published on 21 December 2016

Heat-induced formation of one-dimensional coordination polymers on Au(111): an STM study

Helical Threads: Enantiomerically Pure Carbo[6]Helicene Oligomers

scientific article published on 18 September 2017

Helicene Monomers and Dimers: Chiral Chromophores Featuring Strong Circularly Polarized Luminescence

scientific article published on 20 May 2019

Helicene Quinones: Redox-Triggered Chiroptical Switching and Chiral Recognition of the Semiquinone Radical Anion Lithium Salt by Electron Nuclear Double Resonance Spectroscopy

scientific article published on 03 September 2014

High-affinity inhibitors of Zymomonas mobilis tRNA-guanine transglycosylase through convergent optimization

scientific article published on 17 August 2013

High-affinity inhibitors of tRNA-guanine transglycosylase replacing the function of a structural water cluster

scientific article published in October 2009

Higher Adducts of C60 by Tether-Directed Remote Functionalization: X-Ray Crystal Structure and Reactivity of a Chiral Hexakis-Cyclopropanated Fullerene with all Addends Located along an Equatorial Belt

scientific article published on 01 November 2000

Highly efficient third-order optical nonlinearities in donor-substituted cyanoethynylethene molecules

scientific article published on 01 November 2005

Homochiral [2]Catenane and Bis[2]catenane from Alleno-Acetylenic Helicates - A Highly Selective Narcissistic Self-Sorting Process

scientific article published on 25 September 2015

Homoconjugated push-pull and spiro systems: intramolecular charge-transfer interactions and third-order optical nonlinearities

scientific article published on 01 August 2010

How to replace the residual solvation shell of polar active site residues to achieve nanomolar inhibition of tRNA-guanine transglycosylase

scientific article

Hydrogen-Bonded Networks: Molecular Recognition of Cyclic Alcohols in Enantiopure Alleno-Acetylenic Cage Receptors

scientific article published on 12 November 2018

Identification of 1,3-diiminoisoindoline carbohydrazides as potential antimalarial candidates

scientific article

Impact of protein and ligand impurities on ITC-derived protein-ligand thermodynamics

article

Improved Inhibitors of Trypanothione Reductase by Combination of Motifs: Synthesis, Inhibitory Potency, Binding Mode, and Antiprotozoal Activities

scientific article published on 16 December 2010

Inhibition of the Cysteine Protease Human Cathepsin L by Triazine Nitriles: Amide⋅⋅⋅Heteroarene π-Stacking Interactions and Chalcogen Bonding in the S3 Pocket

scientific article published on 19 December 2016

Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities

scientific article

Inhibitors of the Herbicidal Target IspD: Allosteric Site Binding

scientific article published on July 18, 2011

Inhibitors of the kinase IspE: structure-activity relationships and co-crystal structure analysis

scientific article

Intense Ground-State Charge-Transfer Interactions in Low-Bandgap, Panchromatic Phthalocyanine-Tetracyanobuta-1,3-diene Conjugates

Intense Ground-State Charge-Transfer Interactions in Low-Bandgap, Panchromatic Phthalocyanine-Tetracyanobuta-1,3-diene Conjugates

Interactions with aromatic rings in chemical and biological recognition

scientific article

Ion-Pair Complexation with a Cavitand Receptor

scientific article published on 01 July 2010

Isolation of C76, a chiral (D 2) allotrope of carbon

scientific article published in Nature

Launching Spiking Ligands into a Protein–Protein Interface: A Promising Strategy To Destabilize and Break Interface Formation in a tRNA Modifying Enzyme

scientific article published on May 14, 2013

Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series

scientific article published on 20 May 2015

Limitations on the use of UV/Vis spectroscopy for the evaluation of conjugation effectiveness

scientific article

Linear Monodisperse π-Conjugated Oligomers: Model Compounds for Polymers and More

scientific article published on 01 May 1999

Luminescence and absorption spectra of carbon (C60) films

article

Macrocyclic Cyclo[n]malonates – Synthetic Aspects and Observation of Columnar Arrangements by X-ray Crystallography

Mapping the fluorophilicity of a hydrophobic pocket: synthesis and biological evaluation of tricyclic thrombin inhibitors directing fluorinated alkyl groups into the p pocket

scientific article published in November 2006

Mechanism of Allosteric Inhibition of the Enzyme IspD by Three Different Classes of Ligands

scientific article

Mechanistic investigation of the dipolar [2+2] cycloaddition-cycloreversion reaction between 4-(N,N-dimethylamino)phenylacetylene and arylated 1,1-dicyanovinyl derivatives to form intramolecular charge-transfer chromophores

scientific article published in January 2010

Medicinal chemistry in academia: molecular recognition with biological receptors

scientific article published on 12 February 2004

Modeling the Supramolecular Properties of Aliphatic-Aromatic Hydrocarbons with Convex-Concave Topology

scientific article published on 01 December 1998

Modification of supramolecular binding motifs induced by substrate registry: formation of self-assembled macrocycles and chain-like patterns

scientific article published in October 2009

Molecular Recognition and Cocrystallization of Methylated and Halogenated Fragments of Danicalipin A by Enantiopure Alleno-Acetylenic Cage Receptors

scientific article published on 01 March 2020

Molecular Recognition with Resorcin[4]arene Cavitands: Switching, Halogen-Bonded Capsules, and Enantioselective Complexation.

scientific article published on 16 February 2018

Molecular Structure and Spectroscopic Properties of Kekulene

Molecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitors

scientific article

Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor

scientific article

Molecular recognition at the active site of factor Xa: cation-π interactions, stacking on planar peptide surfaces, and replacement of structural water

scientific article

Molecular recognition in chemical and biological systems

scientific article

Molecular torsion balances: evidence for favorable orthogonal dipolar interactions between organic fluorine and amide groups

scientific article published in January 2007

Molekulare Torsionswaagen: Anzeichen für attraktive orthogonale dipolare Wechselwirkungen zwischen organischem Fluor und Amidgruppen

Monodisperse Poly(triacetylene) Rods: Synthesis of a 11.9 nm Long Molecular Wire and Direct Determination of the Effective Conjugation Length by UV/Vis and Raman Spectroscopies

scientific article published on 01 March 1999

Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors

scientific article published in 2006

N,N'-Dicyanoquinone diimide-derived donor-acceptor chromophores: conformational analysis and optoelectronic properties

scientific article published on 29 November 2011

N-arylated 3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]azepines: axially chiral donors with high helical twisting powers for nonplanar push-pull chromophores

scientific article published in September 2009

Nanoscale engineering of molecular porphyrin wires on insulating surfaces

scientific article published in August 2008

New Rebek imide-type receptors for adenine featuring acetylene-linked pi-stacking platforms.

scientific article published on 10 June 2004

New donor-acceptor chromophores by formal [2+2] cycloaddition of donor-substituted alkynes to dicyanovinyl derivatives

scientific article published on 10 February 2009

New organofluorine building blocks: inhibition of the malarial aspartic proteases plasmepsin II and IV by alicyclic alpha,alpha-difluoroketone hydrates

scientific article

Non-planar push-pull chromophores

scientific article published on 17 February 2010

Nonlinear Optics on the Silicon Platform

Nonphosphate inhibitors of IspE protein, a kinase in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy.

scientific article published in June 2007

Nonplanar Push–Pull Chromophores for Opto-Electronic Applications

scientific article published on January 1, 2010

Novel extended tetrathiafulvalenes based on acetylenic spacers: synthesis and electronic properties

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