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List of works by Arndt Borkhardt

5% of healthy newborns have an ETV6-RUNX1 fusion as revealed by DNA-based GIPFEL screening

scientific article published on 8 January 2018

A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma

scientific article published on 9 June 2016

A novel homozygous Fas ligand mutation leads to early protein truncation, abrogation of death receptor and reverse signaling and a severe form of the autoimmune lymphoproliferative syndrome

scientific article published on 24 October 2014

A novel homozygous mutation in UNC13D presenting as Epstein-Barr-virus-associated lymphoproliferative disease at 9 years of age.

scientific article

A novel mtDNA large-scale mutation clinically exclusively presenting with refractory anemia: is there a chance to predict disease progression?

scientific article published on May 2012

ATM activity in T cells is critical for immune surveillance of lymphoma in vivo

scientific article published on 05 November 2019

ATRT-07. TARGETING PRIMARY CILIOGENESIS IN ATYPICAL TERATOID/RHABDOID TUMORS

scientific article published on 23 April 2019

ATRT-34. TARGETING PRIMARY CILIOGENESIS IN ATYPICAL TERATOID/RHABDOID TUMORS

scientific article published on 22 June 2018

Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling

scientific article published on 01 September 2018

Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

scientific article

Accurate and scalable variant calling from single cell DNA sequencing data with ProSolo

scientific article published on 18 November 2021

Activation-induced cytidine deaminase prevents pro-B cell acute lymphoblastic leukemia by functioning as a negative regulator in Rag1 deficient pro-B cells

scientific article published on 7 September 2017

Acute myeloid leukemia presenting with diabetes insipidus

scientific article published on 01 March 2002

Advance care planning and outcome in pediatric palliative home care.

scientific article

Agammaglobulinemia and lack of immunization protection in exudative atopic dermatitis ⬇️

scientific article published on April 28, 2013

Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies

scientific article

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis

scientific article

An immunodeficiency disease with RAG mutations and granulomas

scientific article published in May 2008

An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia

scientific article published on 03 February 2022

An intact gut microbiome protects genetically predisposed mice against leukemia

scientific article published on 10 September 2020

Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides

scientific article published in April 2003

Analysis of the adenomatous polyposis coli (APC) gene in childhood and adolescent germ cell tumors.

scientific article published on 12 November 2010

Anti-leukaemic activity of a novel haploidentical-transplantation approach employing unmanipulated bone marrow followed by CD6-depleted peripheral blood stem cells in children with refractory/relapsed acute leukaemia

scientific article published on 06 July 2013

Association of nephrotic syndrome with immune reconstitution inflammatory syndrome ⬇️

scientific article published on December 29, 2011

Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors

scientific article published on 30 May 2018

Author Correction: The landscape of genomic alterations across childhood cancers

scientific article published in Nature

Autism spectrum disorder and Li-Fraumeni syndrome: purely coincidental or mechanistically associated?

scientific article published on 5 October 2017

BIOL-02. CELLULAR HETEROGENEITY CONTRIBUTES TO THE AGGRESSIVE BEHAVIOR OF MYC-DRIVEN MEDULLOBLASTOMA

scientific article published on 23 April 2019

Biochemical and bioinformatic methods for elucidating the role of RNA-protein interactions in posttranscriptional regulation

scientific article

CD4(+)and CD8(+)T-cell reactions against leukemia-associated- or minor-histocompatibility-antigens in AML-patients after allogeneic SCT.

scientific article published on 27 October 2013

COL2A1 mutation as a cause of premature osteoarthritis in a 13-year-old child

scientific article published on 6 August 2013

Cancer susceptibility syndromes in children in the area of broad clinical use of massive parallel sequencing.

scientific article published on 16 May 2015

Cell Fate Decisions: The Role of Transcription Factors in Early B-cell Development and Leukemia

scientific article published on 14 September 2020

Challenges of palliative care in children with inborn metabolic diseases.

scientific article published on 9 July 2018

Characterization of leukemia-specific NK cell subsets against acute lymphoblastic leukemia in children.

scientific article

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology

scientific article published on 7 February 2017

Clearance of treatment-refractory adenoviremia via adenovirus-specific donor T-cell transfer during aplasia after αβTCR-CD19-depleted stem cell transplantation

scientific article published on 01 April 2019

Clinical characteristics and outcome of 60 pediatric patients with malignant melanoma registered with the German Pediatric Rare Tumor Registry (STEP).

scientific article published on 10 October 2017

Clofarabine increases the eradication of minimal residual disease of primary Bprecursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome

scientific article published in 2021

Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27.

scientific article published on 16 July 2012

Combined polymerase chain reaction methods to detect c-myc/IgH rearrangement in childhood Burkitt's lymphoma for minimal residual disease analysis.

scientific article published on July 2004

Congenital embryonal rhabdomyosarcoma caused by heterozygous concomitant PTCH1 and PTCH2 germline mutations.

scientific article

Control of AC133/CD133 and impact on human hematopoietic progenitor cells through nucleolin.

scientific article

Correction to: Genetic predisposition in children with cancer - affected families' acceptance of Trio-WES.

scientific article published on 6 November 2017

Correction: Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial

scientific article published on 25 November 2019

Corrigendum to: Biochemical and bioinformatic methods for elucidating the role of RNA-protein interactions in posttranscriptional regulation

scientific article published on 01 November 2019

Cytokine Release Patterns in Mixed Lymphocyte Culture (MLC) of T-Cells with Dendritic Cells (DC) Generated from AML Blasts Contribute to Predict anti-Leukaemic T-Cell Reactions and Patients' Response to Immunotherapy

scientific article published on 7 September 2016

Daunorubicin during delayed intensification decreases the incidence of infectious complications - a randomized comparison in trial CoALL 08-09

scientific article published on 03 July 2018

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

scientific article

Denoising DNA deep sequencing data-high-throughput sequencing errors and their correction

scientific article

Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease

scientific article published on 25 June 2015

Diagnostic challenges in a child with early onset desmoplastic medulloblastoma and homozygous variants in MSH2 and MSH6.

scientific article published on 4 January 2018

Dizygotic twins discordant for HIV-1 despite vertical transmission prophylaxis: was human leukocyte antigen homozygosity of disadvantage to the infected twin? ⬇️

scientific article published on September 10, 2010

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group

scientific article

EBV Negative Lymphoma and Autoimmune Lymphoproliferative Syndrome Like Phenotype Extend the Clinical Spectrum of Primary Immunodeficiency Caused by STK4 Deficiency

EPCAM-A novel molecular target for the treatment of pediatric and adult germ cell tumors.

scientific article

EPEN-08. PHARMACOGENOMICS REVEALS ERBB2 AS A THERAPEUTIC TARGET IN PRIMARY EPENDYMOMA CULTURES

scientific article published on 23 April 2019

EPEN-34. HIGH-THROUGHPUT DRUG SCREENING OF PRIMARY CULTURES REVEALS IRREVERSIBLE ERBB2 INHIBITION AS NOVEL THERAPEUTIC VULNERABILITY OF EPENDYMOMAS

Effective treatment of spasticity using dronabinol in pediatric palliative care.

scientific article published on 30 July 2016

Embryonal rhabdomyosarcoma in a patient with a heterozygous frameshift variant in the DICER1 gene and additional manifestations of the DICER1 syndrome

scientific article

Emergence of translocation t(9;11)-positive leukemia during treatment of childhood acute lymphoblastic leukemia.

scientific article

End-of-life care in children with hematologic malignancies

scientific article published on 23 September 2017

Epigenetic Priming in Cancer Initiation

scientific article published on 01 June 2018

Epigenetic maintenance of stemness and malignancy in peripheral neuroectodermal tumors by EZH2.

scientific article published on 5 July 2009

Experiences in palliative home care of infants with life-limiting conditions.

scientific article

Extremely low-frequency magnetic fields and risk of childhood leukemia: A risk assessment by the ARIMMORA consortium

scientific article

Family-based germline sequencing in children with cancer

scientific article published on 10 October 2018

Fatal Lymphoproliferative Disease in Two Siblings Lacking Functional FAAP24.

scientific article published on 29 July 2016

Fatal Outcome Despite Full Lympho-Hematopoietic Reconstitution After Allogeneic Stem Cell Transplantation in Atypical Ataxia Telangiectasia ⬇️

scientific article published on February 23, 2012

Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment

scientific article published on 07 April 2020

Front-line imatinib treatment in children and adolescents with chronic myeloid leukemia: results from a phase III trial

scientific article published on 20 June 2018

GEMMs addressing Pax5 loss-of-function in childhood pB-ALL.

scientific article

Genetic predisposition in children with cancer - affected families' acceptance of Trio-WES.

scientific article published on 19 September 2017

Genetically engineered mouse models of human B-cell precursor leukemias

scientific article published on January 2014

Genomic Inverse PCR for Screening of Preleukemic Cells in Newborns (GIPFEL Technology)

scientific article published on 01 January 2021

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

scientific article published on 29 March 2019

Genomic inverse PCR for exploration of ligated breakpoints (GIPFEL), a new method to detect translocations in leukemia

scientific article

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

scientific article

Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation

scientific article published on May 2009

Graft versus leukemia effect after haploidentical HSCT in a MLL-negative infant AML with HLXB9/ETV6 rearrangement

scientific article published on 01 April 2008

HIV-1 Subtype Diversity and Prevalence of Primary Drug Resistance in a Single-Center Pediatric Cohort in Germany

scientific article published on 5 July 2017

HIV-1 seroreversion following antiretroviral therapy in an HIV-infected child initially presenting with acquired immunodeficiency syndrome

scientific article published on 01 January 2010

HIV-1 seroreversion in HIV-1-infected children: do genetic determinants play a role?

scientific article published on February 2014

Hematopoietic Stem Cell Transplantation in an Infant with Immunodeficiency, Centromeric Instability, and Facial Anomaly Syndrome.

scientific article

Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial

scientific article published on 02 October 2019

High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma

scientific article (publication date: February 2004)

High incidence of Epstein-Barr virus (EBV)-positive Hodgkin lymphoma and Hodgkin lymphoma-like B-cell lymphoproliferations with EBV latency profile 2 in children with interleukin-2-inducible T-cell kinase deficiency

scientific article published on 24 February 2015

Hodgkin lymphoma as a novel presentation of familial DICER1 syndrome

scientific article published on 3 November 2015

Homeobox Protein HB9 Binds to the Prostaglandin E Receptor 2 Promoter and Inhibits Intracellular cAMP Mobilization in Leukemic Cells ⬇️

scientific article published on October 8, 2012

Homozygous HOXB1 loss-of-function mutation in a large family with hereditary congenital facial paresis

scientific article published on 04 May 2016

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

scientific article

Human RAD52 - a novel player in DNA repair in cancer and immunodeficiency

scientific article published on 15 December 2016

IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

scientific article published on 2 March 2018

IL-2-inducible T-cell kinase deficiency: clinical presentation and therapeutic approach ⬇️

scientific article published on November 25, 2010

Identification of ITK deficiency as a novel genetic cause of idiopathic CD4+ T-cell lymphopenia

scientific article

Identification of TEL-AML1 (ETV6-RUNX1) associated DNA and its impact on mRNA and protein output using ChIP, mRNA expression arrays and SILAC

scientific article published on 27 May 2014

Immunosuppressive therapy for aplastic anemia in children: a more severe disease predicts better survival

scientific article published on 2 June 2005

Improved effector function of leukemia-specific T-lymphocyte clones trained with AML-derived dendritic cells

scientific article published in September 2008

Improving Stratification for Children With Late Bone Marrow B-Cell Acute Lymphoblastic Leukemia Relapses With Refined Response Classification and Integration of Genetics

scientific article published on 23 October 2019

In vitro-induced response patterns of antileukemic T cells: characterization by spectratyping and immunophenotyping ⬇️

scientific article published on March 23, 2012

Induction of trained immunity by influenza vaccination - impact on COVID-19

scientific article published on 25 October 2021

Infection Exposure Promotes ETV6-RUNX1 Precursor B-cell Leukemia via Impaired H3K4 Demethylases.

scientific article

Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility

scientific article published on 25 September 2015

Infection as a cause of childhood leukemia: virus detection employing whole genome sequencing

scientific article published on 2 February 2017

Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID

scientific article published on 05 December 2019

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

scientific article

Insights into the prenatal origin of childhood acute lymphoblastic leukemia

scientific article published on 01 March 2020

Integrated genomics elucidates relative spatial homogeneity of embryonal brain tumors.

scientific article

Interleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects

scientific article

JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility

scientific article published on 09 April 2019

KIR ligand C2 is associated with increased susceptibility to childhood ALL and confers an elevated risk for late relapse.

scientific article published on 27 August 2014

Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi).

scientific article

LGG-08. PROTEOGENOMICS REVEALS TWO DISTINCT BIOLOGICAL PILOCYTIC ASTROCYTOMA SUBGROUPS

scientific article published on 23 April 2019

LGG-10. PROTEOGENOMICS DISCRIMINATES PEDIATRIC AND ADULT PILOCYTIC ASTROCYTOMA AS DISTINCT BIOLOGICAL ENTITIES.

scientific article published on 31 May 2017

LGG-38. PROTEOGENOMICS REVEALS THREE DISTINCT BIOLOGICAL PILOCYTIC ASTROCYTOMA SUBGROUPS

Lack of association between KIR genes and acute lymphoblastic leukemia in children

scientific article published on 01 September 2012

Level of MYC overexpression in pediatric Burkitt's lymphoma is strongly dependent on genomic breakpoint location within the MYC locus

scientific article published on 01 October 2004

Lmo2 expression defines tumor cell identity during T-cell leukemogenesis

scientific article published on 07 June 2018

Loss of Pax5 exploits Sca1-BCR-ABLp190 susceptibility to confer the metabolic shift essential for pB-ALL.

scientific article published on 28 February 2018

Loss of p19Arf in a Rag1(-/-) B-cell precursor population initiates acute B-lymphoblastic leukemia

scientific article

Low incidence of symptomatic osteonecrosis after allogeneic HSCT in children with high-risk or relapsed ALL - results of the ALL-SCT 2003 trial

scientific article published on 20 July 2018

Lowest numbers of primary CD8(+) T cells can reconstitute protective immunity upon adoptive immunotherapy

scientific article published on 22 May 2014

Lymphnode tuberculosis in a 4-year-old boy with relapsed ganglioneuroblastoma: a case report

scientific article published on 5 March 2018

MBRS-16. HDAC AND NFκB ANTAGONISTS SYNERGISTICALLY INHIBIT GROWTH OF MYC-DRIVEN MEDULLOBLASTOMA

MEDU-20. HDAC AND NFκB ANTAGONISTS SYNERGISTICALLY INHIBIT GROWTH OF MYC-DRIVEN MEDULLOBLASTOMA

scientific article published on 23 April 2019

MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells

scientific article

Massively Distended Abdomen Caused by Fibromatosis Previously Misdiagnosed as Myxofibrosarcoma

scientific article published on 31 October 2016

Medical history and clinical examinations are insufficient to exclude vertical human immunodeficiency virus transmission in healthy, at-risk adolescents

scientific article published on 11 April 2019

Metabolic gatekeeper function of B-lymphoid transcription factors

scientific article published on 13 February 2017

MicroRNA in chronic lymphocytic leukemia

scientific article published on 01 February 2006

MicroRNAs Distinguish Cytogenetic Subgroups in Pediatric AML and Contribute to Complex Regulatory Networks in AML-Relevant Pathways ⬇️

scientific article published on February 13, 2013

Minimal residual disease after induction is the strongest predictor of prognosis in intermediate risk relapsed acute lymphoblastic leukaemia - long-term results of trial ALL-REZ BFM P95/96.

scientific article published on 19 December 2012

Mixed lineage leukemia-rearranged childhood pro-B and CD10-negative pre-B acute lymphoblastic leukemia constitute a distinct clinical entity

scientific article published in May 2006

Modeling the process of childhood ETV6-RUNX1 B-cell leukemias.

scientific article published on 27 September 2017

Monitoring minimal residual disease in children with high-risk relapses of acute lymphoblastic leukemia: prognostic relevance of early and late assessment

scientific article published on 9 March 2015

Mouse models for pre-clinical drug testing in leukemia

scientific article

Multicomponent synthesis, binding mode and structure-activity relationships of selective histone deacetylase 6 (HDAC6) inhibitors with bifurcated capping groups

scientific article published on 17 August 2020

Mutated SON putatively causes a cancer syndrome comprising high-risk medulloblastoma combined with café-au-lait spots

scientific article published on 01 July 2019

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

scientific article published on 19 September 2008

Mycoplasma salivarium as a dominant coloniser of Fanconi anaemia associated oral carcinoma

scientific article

NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms.

scientific article published in December 2004

Neurotoxic side effects in children with refractory or relapsed T-cell malignancies treated with nelarabine based therapy

scientific article

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study

scientific article published on 28 July 2016

Next-generation-sequencing of recurrent childhood high hyperdiploid acute lymphoblastic leukemia reveals mutations typically associated with high risk patients

scientific article

Next-generation-sequencing-spectratyping reveals public T-cell receptor repertoires in pediatric very severe aplastic anemia and identifies a β chain CDR3 sequence associated with hepatitis-induced pathogenesis.

scientific article published on 28 May 2013

Next‐generation‐sequencing‐based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia ⬇️

scientific article published on March 18, 2013

Occurrence of an MLL/LAF4 fusion gene caused by the insertion ins(11;2)(q23;q11.2q11.2) in an infant with acute lymphoblastic leukemia

scientific article published on 01 May 2003

Osteonecrosis develops independently from radiological leukemic infiltration of bone in adolescents with acute lymphoblastic leukemia - first findings of the OPAL trial

scientific article

Osteonecrosis in children and adolescents with acute lymphoblastic leukemia: a therapeutic challenge

scientific article published on 13 June 2017

Osteonecrosis in children with acute lymphoblastic leukemia

scientific article

Osteonecrosis in children with acute lymphoblastic leukemia at initial diagnosis and prior to any chemotherapy

scientific article published on 02 May 2018

Outcome of relapse after allogeneic HSCT in children with ALL enrolled in the ALL-SCT 2003/2007 trial

scientific article published on 28 November 2017

Palliative care for children with a yet undiagnosed syndrome.

scientific article

Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets

scientific article published on 01 October 2019

Penetrance and Expressivity in Inherited Cancer Predisposing Syndromes

scientific article published on 20 September 2018

Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia

scientific article

Phase II window study on rituximab in newly diagnosed pediatric mature B-cell non-Hodgkin's lymphoma and Burkitt leukemia

scientific article published on June 2010

Preemptive immunotherapy in childhood acute myeloid leukemia for patients showing evidence of mixed chimerism after allogeneic stem cell transplantation

scientific article published on 26 September 2011

Presence of centromeric but absence of telomeric group B KIR haplotypes in stem cell donors improve leukaemia control after HSCT for childhood ALL

scientific article published on 14 May 2019

Prognostic value of minimal residual disease quantification before allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia: the ALL-REZ BFM Study Group

scientific article published on 8 December 2008

Promising therapy results for lymphoid malignancies in children with chromosomal breakage syndromes (Ataxia teleangiectasia or Nijmegen-breakage syndrome): a retrospective survey ⬇️

scientific article published on September 19, 2011

QRICH1 variants in Ververi-Brady syndrome - delineation of the genotypic and phenotypic spectrum

scientific article published on 03 October 2020

RAG1 deficiency with a shifting B cell phenotype and chromosomal instability

scientific article published on 26 February 2014

Recurrent Germline Variant in <i>RAD21</i> Predisposes Children to Lymphoblastic Leukemia or Lymphoma

scientific article published on 05 May 2022

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

scientific article

RecurrentRHOAmutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols

article

Regional BCG vaccination policy in former East- and West Germany may impact on both severity of SARS-CoV-2 and incidence of childhood leukemia

scientific article published on 18 June 2020

Results of CoALL 07-03 study childhood ALL based on combined risk assessment by in vivo and in vitro pharmacosensitivity

scientific article published on 01 November 2019

Risk adapted transmission prophylaxis to prevent vertical HIV–1 transmission: Effectiveness and safety of an abbreviated regimen of postnatal oral Zidovudine ⬇️

scientific article published on January 24, 2013

SIG-03. HHIP-AS1 PROMOTES TUMOR SURVIVAL THROUGH STABILIZING DYNEIN COMPLEX 1 IN HEDGEHOG DRIVEN HUMAN BRAIN TUMORS

article published in 2019

Saving the red baby: successful allogeneic cord blood transplantation in Omenn syndrome

scientific article published on 7 December 2008

Selective downregulation of HLA-C and HLA-E in childhood acute lymphoblastic leukaemia

scientific article published on 3 November 2015

Senescent Tumor CD8+ T Cells: Mechanisms of Induction and Challenges to Immunotherapy

scientific article published on 30 September 2020

Significance of Frequencies, Compositions, and/or Antileukemic Activity of (DC-stimulated) Invariant NKT, NK and CIK Cells on the Outcome of Patients With AML, ALL and CLL.

scientific article published in July 2017

Smoldering Development of Acute Megakaryoblastic Leukemia with Clonal Evolution in an Infant without Down Syndrome

scientific article published on 13 November 2017

Specific antibody deficiency and autoinflammatory disease extend the clinical and immunological spectrum of heterozygous NFKB1 loss-of-function mutations in humans

scientific article published on 30 June 2016

Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome

scientific article published in May 2017

Symptoms and management of pediatric patients with incurable brain tumors in palliative home care.

scientific article

Synergistic induction of apoptosis in resistant head and neck carcinoma and leukemia by alkoxyamide-based histone deacetylase inhibitors

scientific article published on 17 December 2020

T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases

scientific article

T-cell leukemogenesis is an inappropriate lineage decision-making process: implications for precision oncology

scientific article published in 2018

TRTH-28. HIGH THROUGHPUT SCREENING OF NOVEL HISTONE DEACETYLASE INHIBITORS FOR EPIGENETIC THERAPY OF PRIMARY BRAIN TUMORS.

scientific article

Temporary blast reduction after immunoglobulin administration for congenital cytomegalovirus infection masking infant leukemia with cryptic MLL rearrangement

scientific article published on 30 June 2006

The Duesseldorf warning signs for primary immunodeficiency: is it time to change the rules?

scientific article published on 8 March 2015

The PARA-suite: PAR-CLIP specific sequence read simulation and processing

scientific article

The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy

scientific article

The cell cycle regulator CCDC6 is a key target of RNA-binding protein EWS.

scientific article published on 9 March 2015

The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells

scholarly article by Deborah Ingenhag et al published January 2019 in Haematologica

The human LASP1 gene is fused to MLL in an acute myeloid leukemia with t(11;17)(q23;q21).

scientific article published in January 2003

The impact of the <scp>COVID</scp>‐19 pandemic on the future incidence of acute lymphoblastic leukaemia in children: Projections for Germany under a <scp>COVID</scp>‐19 related scenario

scientific article published in 2022

The landscape of genomic alterations across childhood cancers

scientific article published on 28 February 2018

The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells

scholarly article by Gal Mazor et al published 13 March 2019 in Cell Death and Disease

The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma

scientific article published on 28 September 2021

The long noncoding RNA TP73-AS1 promotes tumorigenicity of medulloblastoma cells

scientific article published on 12 June 2019

The preleukemic TCF3-PBX1 gene fusion can be generated in utero and is present in ≈0.6% of healthy newborns

scientific article published on 01 October 2019

Toward prevention of childhood ALL by early-life immune training

scientific article published in 2021

Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling

scientific article published in Journal of Biological Chemistry

Transient spontaneous remission in congenital MLL-AF10 rearranged acute myeloid leukemia presenting with cardiorespiratory failure and meconium ileus

scientific article published on 29 August 2016

Treatment and outcomes of patients with relapsed, high‐risk neuroblastoma: Results of German trials ⬇️

scientific article published on 09 December 2010

Treosulfan-based conditioning in DOCK8 deficiency: Complete lympho-hematopoietic reconstitution with minimal toxicity ⬇️

scientific article published on October 14, 2012

Trio sequencing in pediatric cancer and clinical implications.

scientific article

Tumoral stem cell reprogramming as a driver of cancer: Theory, biological models, implications in cancer therapy

scientific article published on 12 February 2014

Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5).

scientific article published in August 2005

Use of allogeneic hematopoietic stem-cell transplantation based on minimal residual disease response improves outcomes for children with relapsed acute lymphoblastic leukemia in the intermediate-risk group

scientific article published on 17 June 2013

Visceral Leishmaniasis as a Possible Reason for Pancytopenia

scientific article published on 29 June 2015

Whole-genome paired-end analysis confirms remarkable genomic stability of atypical teratoid/rhabdoid tumors.

scientific article published on 9 August 2013

YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA

scientific article published on 23 June 2020

c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells.

scientific article published on 28 February 2006

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