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List of works by Roland Martin

A functional basis for the association of HLA class II genes and susceptibility to multiple sclerosis: cellular immune responses to myelin basic protein in a multiplex family

scientific article published on 01 February 1993

A multiple sclerosis-associated variant of CBLB links genetic risk with type I IFN function.

scientific article published on 26 September 2014

A novel population of CD4+CD56+ myelin-reactive T cells lyses target cells expressing CD56/neural cell adhesion molecule

scientific article published on 01 July 1996

A plea for "omics" research in complex diseases such as multiple sclerosis--a change of mind is needed.

scientific article published in July 2004

A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial).

scientific article published on 16 December 2017

A truncation variant of the cation channel P2RX5 is upregulated during T cell activation.

scientific article

A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis

scientific article

Anti-CD25 (daclizumab) monoclonal antibody therapy in relapsing-remitting multiple sclerosis.

scientific article

Antibody responses following induction of antigen-specific tolerance with antigen-coupled cells

article

Antigen-specific therapies in MS - Current concepts and novel approaches.

scientific article published on 03 July 2008

Antigen-specific therapies in multiple sclerosis.

scientific article

Antigen-specific tolerization approaches in multiple sclerosis.

scientific article published on 23 October 2013

Autoantigens act as tissue-specific chemoattractants.

scientific article

Autoimmunity in Lyme disease: molecular cloning of antigens recognized by antibodies in the cerebrospinal fluid.

scientific article

Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases: updated guidelines and recommendations from the EBMT Autoimmune Diseases Working Party (ADWP) and the Joi

scientific article published on 26 September 2019

Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis

scientific article

Autologous hematopoietic stem cell transplantation as a treatment option for aggressive multiple sclerosis.

scientific article published in June 2013

Biomarkers in multiple sclerosis

scientific article published on 01 January 2006

Biomarkers in multiple sclerosis: an update for 2014

scientific article

Boswellic acids reduce Th17 differentiation via blockade of IL-1β-mediated IRAK1 signaling.

scientific article published on 16 February 2014

Brain Citrullination Patterns and T Cell Reactivity of Cerebrospinal Fluid-Derived CD4 T Cells in Multiple Sclerosis

scientific article published on 10 April 2019

Broadly neutralizing human monoclonal JC polyomavirus VP1-specific antibodies as candidate therapeutics for progressive multifocal leukoencephalopathy

scientific article published on 23 September 2015

CD95 expression and CD95-mediated apoptosis of T cells in multiple sclerosis. No differences from normal individuals and no relation to HLA-DR2.

scientific article published in January 1998

Central role of JC virus-specific CD4+ lymphocytes in progressive multi-focal leucoencephalopathy-immune reconstitution inflammatory syndrome.

scientific article published in September 2011

Central role of Th2/Tc2 lymphocytes in pattern II multiple sclerosis lesions

scientific article

Cerebrospinal fluid chitinase 3-like 1 levels are associated with conversion to multiple sclerosis.

scientific article published on 17 March 2010

Chickenpox and multiple sclerosis: a case report

scientific article published on May 1995

Clonotypic analysis of cerebrospinal fluid T cells during disease exacerbation and remission in a patient with multiple sclerosis

scientific article published in February 2006

Community corner. Striking the balance in multiple sclerosis

scientific article published on 01 May 2008

Complex immunomodulatory effects of interferon-beta in multiple sclerosis include the upregulation of T helper 1-associated marker genes.

scientific article

Contrast-enhanced MRI lesions during treatment with interferonbeta-1b predict increase in T1 black hole volume in patients with relapsing-remitting multiple sclerosis.

scientific article published in April 2005

Copolymer-1-induced inhibition of antigen-specific T cell activation: interference with antigen presentation

scientific article published on March 1, 1992

Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis

scientific article

Daclizumab (anti-CD25) in multiple sclerosis.

scientific article

Decrypting the spectrum of antigen-specific T-cell responses: the avidity repertoire of MBP-specific T-cells

scientific article published on 01 January 2000

Deficient Fas expression by CD4+ CCR5+ T cells in multiple sclerosis

scientific article published on 08 August 2006

Degenerate TCR recognition and dual DR2 restriction of autoreactive T cells: implications for the initiation of the autoimmune response in multiple sclerosis

scientific article published on 01 May 2008

Dendritic cells signal T cells in the absence of exogenous antigen.

scientific article

Detailed Characterization of T Cell Receptor Repertoires in Multiple Sclerosis Brain Lesions.

scientific article published on 19 March 2018

Different development of myelin basic protein agonist- and antagonist-specific human TCR transgenic T cells in the thymus and periphery

scientific article published on 01 October 2008

Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87-99)

scientific article published on 01 November 1996

Differential expression of cyclic nucleotide phosphodiesterase 3 and 4 activities in human T cell clones specific for myelin basic protein

scientific article published on 01 August 1997

Dipeptidyl peptidase IV (CD26): role in T cell activation and autoimmune disease

scientific article published on 01 January 2000

Dipeptidyl peptidase IV in inflammatory CNS disease

scientific article published on 01 January 2000

Diversity in fine specificity and T cell receptor usage of the human CD4+ cytotoxic T cell response specific for the immunodominant myelin basic protein peptide 87-106

scientific article published on March 1, 1992

Dynamics and heterogeneity of brain damage in multiple sclerosis

scientific article

EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-gamma and IL-2

scientific article

Early anisotropy changes in the corpus callosum of patients with optic neuritis

scientific article published on 06 May 2008

Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis.

scientific article published on April 2009

Effects of natalizumab treatment on the cerebrospinal fluid proteome of multiple sclerosis patients

scientific article published on 04 February 2013

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

scientific article published on 01 October 2000

Expansion and functional relevance of high-avidity myelin-specific CD4+ T cells in multiple sclerosis.

scientific article published on March 2004

Experimental immunotherapies for multiple sclerosis.

scientific article

Exploring the origins of grey matter damage in multiple sclerosis.

scientific article

Expression pattern of activation and adhesion molecules on peripheral blood CD4+ T-lymphocytes in relapsing-remitting multiple sclerosis patients: a serial analysis

scientific article published on 01 May 1996

Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis.

scientific article

Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals

scientific article published on July 15, 1990

Functional HLA-DM on the surface of B cells and immature dendritic cells.

scientific article

Future immunotherapies in multiple sclerosis.

scientific article

Gene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease

scientific article published on 08 July 2003

Genetics of multiple sclerosis--how could disease-associated HLA-types contribute to pathogenesis?

scientific article published on January 1997

Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.

scientific article published in August 2009

Genomics in multiple sclerosis--current state and future directions.

scientific article published on 2 April 2007

Getting specific: monoclonal antibodies in multiple sclerosis.

scientific article published on June 2008

Glatiramer acetate-reactive peripheral blood mononuclear cells respond to multiple myelin antigens with a Th2-biased phenotype.

scientific article

HLA class I: friend and foe of multiple sclerosis

scientific article published on 01 November 2008

HLA-DR2a is the dominant restriction molecule for the cytotoxic T cell response to myelin basic protein in DR2Dw2 individuals

scientific article published on November 1, 1990

HLA-DRB5*0101 and -DRB1*1501 expression in the multiple sclerosis-associated HLA-DR15 haplotype.

scientific article published on October 2005

Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation

scientific article

Heterogeneity of T-cell receptor alpha-chain complementarity-determining region 3 in myelin basic protein-specific T cells increases with severity of multiple sclerosis.

scientific article

Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis

scientific article

Human T-cell response to myelin basic protein peptide (83-99): extensive heterogeneity in antigen recognition, function, and phenotype

scientific article published on 01 October 1997

Human autoreactive CD4+ T cell clones use perforin- or Fas/Fas ligand-mediated pathways for target cell lysis

scientific article published on 01 March 1997

Human autoreactive CD4+ T cells from naive CD45RA+ and memory CD45RO+ subsets differ with respect to epitope specificity and functional antigen avidity

scientific article published on 01 May 2000

Human autoreactive and foreign antigen-specific T cells resist apoptosis induced by soluble recombinant CD95 ligand.

scientific article published in September 1997

Humanized anti-CD25 antibody treatment with daclizumab in multiple sclerosis.

scientific article published on January 2008

IL7RA haplotype-associated alterations in cellular immune function and gene expression patterns in multiple sclerosis.

scientific article

Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms

scientific article

Immunological aspects of demyelinating diseases

scientific article published on January 1, 1992

Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis and their application for new therapeutic strategies.

scientific article published on January 1997

Immunological questions on hematopoietic stem cell transplantation for multiple sclerosis.

scientific article

Immunology of Multiple Sclerosis

scientific article

Immunology of multiple sclerosis

scientific article published on 01 January 2005

Immunology of progressive multifocal leukoencephalopathy.

scientific article

Immunomodulatory effects of the ether phospholipid edelfosine in experimental autoimmune encephalomyelitis.

scientific article published on 21 July 2014

Immunotherapy of multiple sclerosis: where are we? Where should we go?

scientific article published on September 2001

In search of cerebrospinal fluid biomarkers of fatigue in multiple sclerosis: A proteomics study

scientific article published on 01 July 2018

In vitro modulation of human, autoreactive MBP-specific CD4+ T-cell clones by cyclosporin A

scientific article published in June 1997

Increased frequency and broadened specificity of latent EBV nuclear antigen-1-specific T cells in multiple sclerosis.

scientific article published on 28 March 2006

Increased serum levels of soluble CD95 (APO-1/Fas) in relapsing-remitting multiple sclerosis

scientific article published on 01 January 1998

Infectious causes of multiple sclerosis

scientific article published on 01 October 2006

Inhibitors of dipeptidyl peptidase IV/CD26 suppress activation of human MBP-specific CD4+ T cell clones.

scientific article published in July 1998

Intrathecal effects of daclizumab treatment of multiple sclerosis

scientific article published on November 9, 2011

JC polyomavirus mutants escape antibody-mediated neutralization.

scientific article published on 23 September 2015

Killer immunoglobulin-like receptor locus polymorphisms in multiple sclerosis.

scientific article published on 20 December 2011

Lack of over-expression of T cell receptor Vbeta5.2 in myelin basic protein-specific T cell lines derived from HLA-DR2 positive multiple sclerosis patients and controls.

scientific article

Ligand motif of the autoimmune disease-associated mouse MHC class II molecule H2-A(s)

scientific article published on 01 February 2001

Long-term safety and efficacy of natalizumab in relapsing-remitting multiple sclerosis: impact on quality of life.

scientific article published on 04 April 2014

Longitudinal MRI study: The effects of azathioprine in MS patients refractory to interferon -1b

scientific article published on 10 June 2003

Longitudinal study of myelin basic protein-specific T-cell receptors during the course of multiple sclerosis

scientific article published on 01 September 1997

Loss of retinal nerve fibre layer axons indicates white but not grey matter damage in early multiple sclerosis.

scientific article

MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis

scientific article published on 19 April 2019

Magnetic resonance imaging of labeled T-cells in a mouse model of multiple sclerosis.

scientific article

Mechanisms of immune escape in central nervous system infection with neurotropic JC virus variant

scientific article

Mechanisms of immunomodulation by glatiramer acetate

scientific article published on 01 December 2000

Memory B Cells Activate Brain-Homing, Autoreactive CD4 T Cells in Multiple Sclerosis

scientific article published on 30 August 2018

Molecular mimicry in multiple sclerosis

scientific article published on 01 February 2006

Multiple Sclerosis: Immunotherapy

scientific article published on 01 July 1999

Multiple sclerosis

scientific article published on June 1997

Multiple sclerosis associated amino acids of polymorphic regions relevant for the HLA antigen binding are confined to HLA-DR2

scientific article published on 01 October 2000

Multiple sclerosis. New therapeutic strategies in the experimental stage

scientific article published on February 1997

Multiple sclerosis: a complicated picture of autoimmunity.

scientific article published on September 2007

Multiple sclerosis: are HLA class I molecules involved in disease pathogenesis?

scientific article published on 01 August 1995

Multiple sclerosis: closing in on an oral treatment.

scientific article published in March 2010

Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy.

scientific article

Myelin basic protein-specific T-cell responses in identical twins discordant or concordant for multiple sclerosis

scientific article published on 01 October 1993

Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis.

scientific article

Myelin-associated oligodendrocytic basic protein: identification of an encephalitogenic epitope and association with multiple sclerosis

scientific article published on 01 January 2000

Natalizumab treatment perturbs memory- and marginal zone-like B-cell homing in secondary lymphoid organs in multiple sclerosis.

scientific article published on 27 December 2011

Neuroimmunology of multiple sclerosis and experimental allergic encephalomyelitis.

scientific article

Neutrophils in multiple sclerosis are characterized by a primed phenotype

scientific article published on 09 December 2011

New approaches to investigating heterogeneity in complex traits

scientific article

New drugs may improve, complicate treatment for multiple sclerosis.

scientific article published in March 2010

No proinflammatory signature in CD34+ hematopoietic progenitor cells in multiple sclerosis patients

scientific article published on 17 January 2012

Nogo receptor is involved in the adhesion of dendritic cells to myelin.

scientific article

Nogo-A Antibodies for Progressive Multiple Sclerosis

scientific article published on 19 January 2017

Nogo-A antibodies enhance axonal repair and remyelination in neuro-inflammatory and demyelinating pathology.

scientific article published on 23 June 2017

Peptidic complex mixtures as therapeutic agents in CNS autoimmunity.

scientific article published in February 2004

Peripheral blood cell bulk cultures are not suitable for the analysis of the genetic control of T-cell cytokine function.

scientific article published in August 2001

Phenotypic and functional complexity of brain-infiltrating T cells in Rasmussen encephalitis

scientific article published on 8 December 2017

Preferential expansion of autoreactive T lymphocytes from the memory T-cell pool by IL-7

scientific article published in December 1999

Prevention and therapy of JC polyomavirus-mediated progressive multifocal leukoencephalopathy - a realistic possibility?

scientific article published on 9 November 2017

Primary retinal pathology in multiple sclerosis as detected by optical coherence tomography

scientific article published on 19 May 2011

Quantitative T2' imaging in patients with clinically isolated syndrome

scientific article

Re: GAMES issue

scientific article published on 01 August 2004

Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis.

scholarly article

Ring-enchancement in multiple sclerosis: marker of disease severity

scientific article published on 01 June 2001

Short-term MRI measurements as predictors of EDSS progression in relapsing-remitting multiple sclerosis: grey matter atrophy but not lesions are predictive in a real-life setting

scientific article published on 20 September 2016

Skewed T-cell receptor repertoire in genetically identical twins correlates with multiple sclerosis

scientific article published on 01 July 1993

Sphingosine-1 phosphate and central nervous system

scientific article published on January 2014

Spotlight on anti-CD25: daclizumab in MS.

scientific article published on September 2008

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

scientific article

Sustained efficacy of natalizumab in the treatment of relapsing-remitting multiple sclerosis independent of disease activity and disability at baseline: real-life data from a Swiss cohort.

scientific article

T cell epitope mapping of JC polyoma virus-encoded proteome reveals reduced T cell responses in HLA-DRB1*04:01+ donors

scientific article (publication date: March 2013)

T cell response to 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) in multiple sclerosis patients

scientific article published in September 2002

T cell response to myelin basic protein in the context of the multiple sclerosis-associated HLA-DR15 haplotype: peptide binding, immunodominance and effector functions of T cells

scientific article published on August 1, 1997

T helper 1 (Th1) functional phenotype of human myelin basic protein-specific T lymphocytes.

scientific article published on January 1993

T helper cell differentiation in multiple sclerosis and autoimmunity

scientific article published on 01 November 1998

T lymphocyte priming by neutrophil extracellular traps links innate and adaptive immune responses

scientific article published on 20 February 2012

T-cell clones persisting in the circulation after autologous hematopoietic SCT are undetectable in the peripheral CD34+ selected graft

scientific article published on 22 June 2009

T-cell receptor alpha and beta CDR3 expression by myelin basic protein-specific human T-cell clones

scientific article published on 01 July 1995

T-cell receptor use in multiple sclerosis

scientific article published on 01 July 1995

T-cell response to myelin basic protein and lipid-bound myelin basic protein in patients with multiple sclerosis and healthy donors

scientific article published on February 1, 1998

T2' imaging indicates decreased tissue metabolism in frontal white matter of MS patients.

scientific article published on June 2009

TCR bias and HLA cross-restriction are strategies of human brain-infiltrating JC virus-specific CD4+ T cells during viral infection.

scientific article published on 31 August 2012

TGF-beta1-mediated control of central nervous system inflammation and autoimmunity through the inhibitory receptor CD26

scientific article published on 01 April 2007

Targeting fibrin in neurodegeneration

scientific article published on 15 October 2018

The 3A6-TCR/superagonist/HLA-DR2a complex shows similar interface and reduced flexibility compared to the complex with self-peptide

scientific article published on 25 June 2019

The OSCAR-IB consensus criteria for retinal OCT quality assessment

scientific article

The good and the bad of neuroinflammation in multiple sclerosis.

scientific article published on January 2014

The immunopathogenesis of multiple sclerosis

scientific article published on 01 March 2002

The orally available, synthetic ether lipid edelfosine inhibits T cell proliferation and induces a type I interferon response

scientific article

The value of animal models for drug development in multiple sclerosis.

scientific article

Therapeutic potential of phosphodiesterase type 4 inhibition in chronic autoimmune demyelinating disease

scientific article published on 01 October 1997

Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients.

scientific article

Treating progressive multifocal leukoencephalopathy with interleukin 7 and vaccination with JC virus capsid protein VP1

scientific article published on 11 September 2014

Tuberous sclerosis complex and Wolff-Parkinson-White syndrome

scientific article

Understanding risk of PML through multiple sclerosis

scientific article published on 01 May 2018

Unfavorable Structural and Functional Outcomes in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Optic Neuritis

scientific article published on 01 March 2019

Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.

scientific article published on 12 December 2013

Using stem cells in multiple sclerosis therapies

scientific article published in December 2004

[Progressive multifocal leukoencephalopathy]

scientific article published on 01 December 2016