List of works - Mitchell Lazar

A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver

scientific article published on 18 February 2021

A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass

scientific article published on 11 June 2018

Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers

scientific article

Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold

scientific article published on 26 August 2019

Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor

scientific article

Dichotomous engagement of HDAC3 activity governs inflammatory responses

scientific article published on 05 August 2020

Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.

scientific article published in July 2015

Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo

scientific article published on 8 May 2015

Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.

scientific article

Identification of C2CD4A as a human diabetes susceptibility gene with a role in β cell insulin secretion

scientific article published on 16 September 2019

PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.

scientific article

REV-ERB nuclear receptors in the suprachiasmatic nucleus control circadian period and restrict diet-induced obesity

scientific article published on 27 October 2021

Regeneration of fat cells from myofibroblasts during wound healing.

scientific article published on 5 January 2017

Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription.

scientific article published on 8 February 2018

SR9009 has REV-ERB-independent effects on cell proliferation and metabolism

scientific article published on 24 May 2019

Shining light on dark matter in the genome

scientific article published on 18 November 2019

Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice.

scientific article published on 27 February 2017

The hepatocyte clock and feeding control chronophysiology of multiple liver cell types

scientific article

List of works by Mitchell Lazar

A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver

A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass

Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers

Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold

Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor

Dichotomous engagement of HDAC3 activity governs inflammatory responses

Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.

Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo

Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.

Identification of C2CD4A as a human diabetes susceptibility gene with a role in β cell insulin secretion

PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.

REV-ERB nuclear receptors in the suprachiasmatic nucleus control circadian period and restrict diet-induced obesity

Regeneration of fat cells from myofibroblasts during wound healing.

Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription.

SR9009 has REV-ERB-independent effects on cell proliferation and metabolism

Shining light on dark matter in the genome

Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice.

The hepatocyte clock and feeding control chronophysiology of multiple liver cell types