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List of works by Claudia Cicala

Biochemical and biological characterization of a dodecameric CD4-Ig fusion protein: implications for therapeutic and vaccine strategies

scientific article published on 22 January 2002

Blocking α4β7 integrin binding to SIV does not improve virologic control

scientific article published on 05 September 2019

Broad-spectrum anti-human immunodeficiency virus (HIV) potential of a peptide HIV type 1 entry inhibitor

scientific article published on 24 January 2007

CCR5 Signal Transduction in Macrophages by Human Immunodeficiency Virus and Simian Immunodeficiency Virus Envelopes

Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility

scientific article

Common helical V1V2 conformations of HIV-1 Envelope expose the α4β7 binding site on intact virions

scientific article published in Nature Communications

Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

scientific article published on 14 September 2017

Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques

scientific article published on 13 May 2019

Functional Dynamics of the Interaction between HIV gp120 and α4β7.

scientific article published in October 2014

HIV Envelope gp120 Alters T Cell Receptor Mobilization in the Immunological Synapse of Uninfected CD4 T Cells and Augments T Cell Activation

scientific article

HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication

scientific article

HIV envelope induces virus expression from resting CD4+ T cells isolated from HIV-infected individuals in the absence of markers of cellular activation or apoptosis

scientific article published in March 2003

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

scientific article

HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV ⬇️

scientific article published on January 27, 2011

HIV-1 gp120 Impairs B Cell Proliferation by Inducing TGF-β1 Production and FcRL4 Expression

HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells

article

HIV-1 gp120 inhibits TLR9-mediated activation and IFN-{alpha} secretion in plasmacytoid dendritic cells

scholarly article

HIV-1 gp120: A Target for Therapeutics and Vaccine Design.

scientific article

IL-7 induces expression and activation of integrin α4β7 promoting naive T-cell homing to the intestinal mucosa

scientific article

Integrin α4β7 Blockade Preferentially Impacts CCR6+ Lymphocyte Subsets in Blood and Mucosal Tissues of Naive Rhesus Macaques

scientific article published in December 2017

Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes.

scientific article published in January 2018

MAdCAM costimulation through Integrin-α4β7 promotes HIV replication

scientific article published on 06 June 2018

Neutralizing and Targeting Properties of a New Set of α4β7-Specific Antibodies Are Influenced by Their Isotype

scientific article published on 7 February 2017

Neutrophil recruitment to lymph nodes limits local humoral response to Staphylococcus aureus

scientific article

Polymorphisms in the α4 integrin of neotropical primates: insights for binding of natural ligands and HIV-1 gp120 to the human α4β7

scientific article

R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells

scholarly article

Role of T-cell trafficking in the pathogenesis of HIV disease

scientific article published on 01 March 2019

SARS-CoV-2 genomic and quasispecies analyses in cancer patients reveal relaxed intrahost virus evolution

scientific article published on 26 August 2020

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7

article

Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids.

scientific article

Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120.

scientific article published on 20 February 2018

Species-specific differences in the expression and regulation of α4β7 integrin in various nonhuman primates

scientific article

Structural basis for the interaction between focal adhesion kinase and CD4

scientific article

Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy

scientific article

Targeted lysis of HIV-infected cells by natural killer cells armed and triggered by a recombinant immunoglobulin fusion protein: implications for immunotherapy.

scientific article published on February 2005

Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection

scientific article

The Genotype of Early-Transmitting HIV gp120s Promotes α4β7 –Reactivity, Revealing α4β7+/CD4+ T cells As Key Targets in Mucosal Transmission ⬇️

scientific article published on February 24, 2011

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression

scientific article published on 27 October 2013

The HIV-1 envelope protein gp120 is captured and displayed for B cell recognition by SIGN-R1(+) lymph node macrophages

scientific article

The Role of Integrin α4β7 in HIV Pathogenesis and Treatment

scientific article published on 24 February 2018

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

scientific article

The role of the CD4 receptor versus HIV coreceptors in envelope-mediated apoptosis in peripheral blood mononuclear cells

scientific article published on 01 January 2002

Virion attachment and entry: HIV gp120 Env biotinylation, gp120 Env, or integrin ligand-binding assay

scientific article published on January 2014

Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing

scientific article published on May 2017

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