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List of works by Claire Lugnier

A new peptide (1150Da) selectively activates the calcium-calmodulin sensitive isoform of cyclic nucleotide phosphodiesterase from human myometrium ⬇️

scientific article published on April 30, 1992

Angiotensin II Potentiates Vasopressin-Dependent cAMP Accumulation in CHO Transfected Cells. Mechanisms of Cross-Talk Between AT1A and V2 Receptors ⬇️

scientific article published on 01 January 1998

Bepridil and flunarizine as calmodulin inhibitors ⬇️

scientific article published on February 10, 1984

Biflavones of Decussocarpus rospigliosii as phosphodiesterases inhibitors.

scientific article published on 24 September 2007

Characterization of cyclic nucleotide phosphodiesterases from cultured bovine aortic endothelial cells

scientific article published on 01 January 1990

Concerted Regulation of cGMP and cAMP Phosphodiesterases in Early Cardiac Hypertrophy Induced by Angiotensin II ⬇️

scientific article published on December 3, 2010

Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling

scientific article published on 12 March 2014

Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments ⬇️

scientific article published on March 1, 2012

Cyclic nucleotide phosphodiesterases (PDE) and peptide motifs

scientific article

Delphinidin Inhibits Tumor Growth by Acting on VEGF Signalling in Endothelial Cells

scientific article

Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model

scientific article published on 22 May 2019

Design, Synthesis, Pharmacological Evaluation and Vascular Effects of Delphinidin Analogues

scientific article published on 01 January 2018

Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors

scientific article

Disease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitor

scientific article

Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis ⬇️

scientific article published on August 31, 2010

Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress.

scientific article published on 7 April 2019

Endothelium-independent vasorelaxant effect of a Berberis orthobotrys root extract via inhibition of phosphodiesterases in the porcine coronary artery

scientific article published on 06 May 2016

Inhibition by papaverine of cGMP and cAMP phosphodiesterases from the rat heart.

scientific article

Involvement of cyclic nucleotide-dependent protein kinases in cyclic AMP-mediated vasorelaxation

scientific article

La Société de Biologie de Strasbourg : 100 ans au service de la science et de la société

scientific article published on 24 December 2020

NCS 613, a PDE4 inhibitor, by increasing cAMP level suppresses systemic inflammation and immune complexes deposition in kidney of MRL/lpr lupus- prone mice

scientific article published on 20 November 2020

NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues ⬇️

scientific article published on July 22, 2011

Relationships between structure and vascular activity in a series of benzylisoquinolines ⬇️

scientific article published on October 1, 1997

Therapeutic potentials of natural compounds acting on cyclic nucleotide phosphodiesterase families.

scientific article

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