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List of works by Margaret C. M. Smith

A flexible mathematical model platform for studying branching networks: experimentally validated using the model actinomycete, Streptomyces coelicolor.

scientific article published on 18 February 2013

A novel Streptomyces spp. integration vector derived from the S. venezuelae phage, SV1

scientific article

A phage protein that binds φC31 integrase to switch its directionality ⬇️

scientific article published on May 25, 2011

Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome

scientific article

An efficient method for the in vitro production of azol(in)e-based cyclic peptides.

scientific article published on 21 October 2014

An enzymatic route to selenazolines

scientific article

An operator associated with autoregulation of the repressor gene in actinophage phiC31 is found in highly conserved copies in intergenic regions in the phage genome.

scientific article published on March 1994

An operon encoding enzymes for synthesis of a putative extracellular carbohydrate attenuates acquired vancomycin resistance in Streptomyces coelicolor

scientific article published on 11 January 2019

Characterization of the Streptomyces coelicolor Glycoproteome Reveals Glycoproteins Important for Cell Wall Biogenesis

scientific article published on 25 June 2019

Complete genome sequence of 'Mycobacterium neoaurum' NRRL B-3805, an androstenedione (AD) producer for industrial biotransformation of sterols.

scientific article published on 14 March 2016

Control of lytic development in the Streptomyces temperate phage phi C31.

scientific article published in April 1995

Control of serine integrase recombination directionality by fusion with the directionality factor

scientific article published on 28 June 2017

Cross-resistance is modular in bacteria-phage interactions

article

DNA binding and synapsis by the large C-terminal domain of phiC31 integrase.

scientific article published on 10 June 2009

Disruption of the GDP-mannose synthesis pathway in Streptomyces coelicolor results in antibiotic hyper-susceptible phenotypes.

scientific article published in March 2018

Gated rotation mechanism of site-specific recombination by ϕC31 integrase.

scientific article

Genetic Techniques for Manipulation of the Phytosterol Biotransformation Strain Mycobacterium neoaurum NRRL B-3805

scientific article published on 01 January 2017

Genome integration and excision by a new Streptomyces bacteriophage, ϕJoe.

scientific article published on 21 December 2016

Hypervariation and phase variation in the bacteriophage 'resistome'.

scientific article published on 23 August 2007

Integrating vectors for genetic studies in the rare Actinomycete Amycolatopsis marina

scientific article published on 04 June 2019

Multipart DNA Assembly Using Site-Specific Recombinases from the Large Serine Integrase Family.

scientific article published on January 2017

Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis.

scientific article

New applications for phage integrases.

scientific article published on 22 May 2014

Nucleotide sequence of the Bacillus subtilis argF gene encoding ornithine carbamoyltransferase.

scientific article published on August 1990

Phage-encoded Serine Integrases and Other Large Serine Recombinases.

scientific article published on August 2015

Rapid metabolic pathway assembly and modification using serine integrase site-specific recombination

scientific article

Rearranging the centromere of the human Y chromosome with phiC31 integrase

scientific article

Recombination directionality factor gp3 binds ϕC31 integrase via the zinc domain, potentially affecting the trajectory of the coiled-coil motif.

scientific article published on 8 December 2017

Resistance Evolution against Phage Combinations Depends on the Timing and Order of Exposure

scientific article published on 24 September 2019

Role of the N-terminal domain of phiC31 integrase in attB-attP synapsis.

scientific article published on 8 August 2008

Serine recombinases as tools for genome engineering.

scientific article published on 30 December 2010

Site-specific recombination by phiC31 integrase and other large serine recombinases.

scientific article published on April 2010

Site-specific recombination in Schizosaccharomyces pombe and systematic assembly of a 400kb transgene array in mammalian cells using the integrase of Streptomyces phage phiBT1.

scientific article published on 20 December 2007

Streptomyces coelicolor strains lacking polyprenol phosphate mannose synthase and protein O-mannosyl transferase are hyper-susceptible to multiple antibiotics.

scientific article published in February 2018

Structure of PatF from Prochloron didemni

scientific article

The discovery of new cyanobactins from Cyanothece PCC 7425 defines a new signature for processing of patellamides

scientific article

The dynamic architecture of the metabolic switch in Streptomyces coelicolor.

scientific article

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

scientific article

The mechanism of ϕC31 integrase directionality: experimental analysis and computational modelling.

scientific article published on 07 July 2016

The phage growth limitation system in Streptomyces coelicolor A(3)2 is a toxin/antitoxin system, comprising enzymes with DNA methyltransferase, protein kinase and ATPase activity.

scientific article published on 13 January 2015

Use of an inducible promoter for antibiotic production in a heterologous host.

scientific article published on 2 February 2010

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