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Authors whose works are in public domain in at least one jurisdiction

List of works by Michael H. Gelb

1-50 of 207 results

Biochemistry and physiology of mammalian secreted phospholipases A2.

scientific article published on January 2008

Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development

scientific article

5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis

scientific article published on 8 December 2008

Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2.

scientific article published on 30 September 2002

Direct multiplex assay of lysosomal enzymes in dried blood spots for newborn screening

scientific article

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

scientific article

Heterologous expression of proteins from Plasmodium falciparum: results from 1000 genes

scientific article published on 18 April 2006

Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model

scientific article

Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis

scientific article (publication date: 15 February 2002)

Bactericidal properties of human and murine groups I, II, V, X, and XII secreted phospholipases A(2).

scientific article published on 2 November 2001

Direct multiplex assay of enzymes in dried blood spots by tandem mass spectrometry for the newborn screening of lysosomal storage disorders

scientific article published on April 2006

Identification of infants at risk for developing Fabry, Pompe, or mucopolysaccharidosis-I from newborn blood spots by tandem mass spectrometry

scientific article published on March 2013

Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha

scientific article published on 8 March 2004

Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics.

scientific article

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA

scientific article published on 23 June 2015

Activation of cytokine production by secreted phospholipase A2 in human lung macrophages expressing the M-type receptor

scientific article

The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth

scientific article published on July 1, 1998

Protein farnesyltransferase inhibitors exhibit potent antimalarial activity

scientific article

Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase

scientific article published on 8 October 2004

A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis

scientific article

Thematic review series: lipid posttranslational modifications. Fighting parasitic disease by blocking protein farnesylation

scientific article

Pilot study of newborn screening for six lysosomal storage diseases using Tandem Mass Spectrometry

scientific article published on 20 May 2016

Production of vascular endothelial growth factors from human lung macrophages induced by group IIA and group X secreted phospholipases A2

scientific article

Rational modification of a candidate cancer drug for use against Chagas disease

scientific article published on March 2009

Interfacial enzymology of parvovirus phospholipases A2.

scientific article

Drug discovery for malaria: a very challenging and timely endeavor

scientific article

Recombinant production and properties of binding of the full set of mouse secreted phospholipases A2 to the mouse M-type receptor.

scientific article published on February 2007

Mapping the Interfacial Binding Surface of Human Secretory Group IIa Phospholipase A2

scientific article published on November 25, 1997

Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators

scientific article published on 20 May 2013

Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum

scientific article published on 20 January 2005

Glycogen synthase kinase 3 is a potential drug target for African trypanosomiasis therapy

scientific article published on 21 July 2008

Newborn Screening for Lysosomal Storage Diseases

scientific article published on December 4, 2014

High-level expression in Escherichia coli and rapid purification of enzymatically active honey bee venom phospholipase A2

scientific article published on December 2, 1992

Calcium-Dependent and -Independent Interfacial Binding and Catalysis of Cytosolic Group IV Phospholipase A2

scientific article published on June 9, 1998

The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity

scientific journal article

Docking Phospholipase A 2 on Membranes Using Electrostatic Potential-Modulated Spin Relaxation Magnetic Resonance

scientific article published on March 20, 1998

Novel Mammalian Group XII Secreted Phospholipase A2Lacking Enzymatic Activity,

scientific article published on October 7, 2003

On the binding preference of human groups IIA and X phospholipases A2 for membranes with anionic phospholipids

scientific article published on 19 September 2002

Interfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms

scientific article

The natural history of embouchure dystonia

scientific article published on September 1, 2001

Group V secretory phospholipase A2 modulates phagosome maturation and regulates the innate immune response against Candida albicans.

scientific article published on April 2009

The antibacterial properties of secreted phospholipases A2: a major physiological role for the group IIA enzyme that depends on the very high pI of the enzyme to allow penetration of the bacterial cell wall

scientific article published on 12 November 2001

Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine- and difluorostatone-containing peptides

scientific article published on April 21, 1992

A tandem mass spectrometry triplex assay for the detection of Fabry, Pompe, and mucopolysaccharidosis-I (Hurler).

scientific article published on 12 October 2010

Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII).

scientific article

Potentiation of tumor necrosis factor alpha-induced secreted phospholipase A2 (sPLA2)-IIA expression in mesangial cells by an autocrine loop involving sPLA2 and peroxisome proliferator-activated receptor alpha activation.

scientific article

The protein farnesyltransferase inhibitor Tipifarnib as a new lead for the development of drugs against Chagas disease

scientific article published on August 2005

Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts

scientific journal article

Tandem Mass Spectrometry Has a Larger Analytical Range than Fluorescence Assays of Lysosomal Enzymes: Application to Newborn Screening and Diagnosis of Mucopolysaccharidoses Types II, IVA, and VI

scientific article published on September 14, 2015

Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function.

scientific article published on 31 October 2006