Search filters

List of works by Michael F. Good

'Natural' T cells responsive to malaria: evidence implicating immunological cross-reactivity in the maintenance of TCR alpha beta+ malaria-specific responses from non-exposed donors

scientific article published on September 1992

'Original antigenic sin', T cell memory, and malaria sporozoite immunity: an hypothesis for immune evasion

scientific article published in April 1993

A CTL epitope on the circumsporozoite protein of P. yoelii

scientific article published on January 1990

A case for whole-parasite malaria vaccines.

scientific article published on 28 February 2007

A case of 'hit-and-run' in Plasmodium genetics

scientific article published on 12 September 2006

A lipid core peptide construct containing a conserved region determinant of the group A streptococcal M protein elicits heterologous opsonic antibodies

scientific article

A malaria vaccine strategy based on the induction of cellular immunity

scientific article published on April 1, 1992

A method for the accurate determination of anti-hapten cytotoxic T lymphocyte precursors: Correction for apparent ‘anti-self’ reactivity ⬇️

scientific article published on July 30, 1982

A microbial platform for rapid and low-cost virus-like particle and capsomere vaccines.

scientific article published on 7 June 2011

A novel pathway of haematopoiesis revealed after experimental malaria infection

scientific article published on 20 July 2010

A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria

scientific article

A semi-synthetic whole parasite vaccine designed to protect against blood stage malaria

scientific article published on 17 August 2016

A synthetic M protein peptide synergizes with a CXC chemokine protease to induce vaccine-mediated protection against virulent streptococcal pyoderma and bacteremia

scientific article

A whole parasite vaccine to control the blood stages of Plasmodium – the case for lateral thinking ⬇️

scientific article published on April 21, 2011

Absolute requirement for an active immune response involving B cells and Th cells in immunity to Plasmodium yoelii passively acquired with antibodies to the 19-kDa carboxyl-terminal fragment of merozoite surface protein-1.

scientific article

Activated lymphocyte killer cells derived from melanoma tissue or peripheral blood ⬇️

scientific article published on 01 August 1984

Adapting immunity with subunit vaccines: case studies with group A Streptococcus and malaria

scientific article

Adoptive transfer of CD8+ T cells from immune animals does not transfer immunity to blood stage Plasmodium yoelii malaria

scientific article

Advances in potential M-protein peptide-based vaccines for preventing rheumatic fever and rheumatic heart disease

scientific article published on January 2006

An efficient, chemically-defined semisynthetic lipid-adjuvanted nanoparticulate vaccine development system.

scientific article published on 18 February 2013

Analysis of circumsporozoite protein-specific immune responses following recent infection with Plasmodium vivax.

scientific article published in July 2004

Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins: Paucity of clones responsive to intact parasites

scientific article published in September 1994

Analysis of immunological nonresponsiveness to the 19-kilodalton fragment of merozoite surface Protein 1 of Plasmodium yoelii: rescue by chemical conjugation to diphtheria toxoid (DT) and enhancement of immunogenicity by prior DT vaccination

scientific article

Analysis of true anti-hapten cytotoxic clones in limit dilution microcultures after correction for "anti-self" activity: precursor frequencies, Ly-2 and Thy-1 phenotype, specificity, and statistical methods ⬇️

scientific article published on May 1, 1983

Antibodies to Cryptic Epitopes in Distant Homologues Underpin a Mechanism of Heterologous Immunity between Plasmodium vivax PvDBP and Plasmodium falciparum VAR2CSA

scientific article published on 08 October 2019

Antibodies to neutralising epitopes synergistically block the interaction of the receptor‐binding domain of SARS‐CoV‐2 to ACE 2

scientific article published on 07 March 2021

Antibodies to the conserved region of the M protein and a streptococcal superantigen cooperatively resolve toxic shock-like syndrome in HLA-humanized mice

scientific article published on 04 September 2019

Antibody levels to the class I and II epitopes of the M protein and myosin are related to group A streptococcal exposure in endemic populations

scientific article

Antibody reactivity to linear epitopes of Plasmodium falciparum cytoadherence-linked asexual gene 9 in asymptomatic children and adults from papua new Guinea

scientific article published on June 2005

Antigenic diversity in Plasmodium falciparum.

scientific article published on January 1988

Antigens released at schizont burst stimulate Plasmodium falciparum-specific CD4+ T cells from non-exposed donors: potential for cross-reactive memory T cells to cause disease

scientific article published on May 1995

Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria

scientific article published on 08 July 2013

Assessment of human cytotoxic T cell activity using synthetic peptides: potential for field application

scientific article

Back to the future for antiparasite vaccines?

scientific article published in January 2013

CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites

scientific article published on January 1988

CD8+ T lymphocyte-mediated loss of marginal metallophilic macrophages following infection with Plasmodium chabaudi chabaudi AS.

scientific article published in August 2006

Can class I epitope of M protein be a diagnostic marker for rheumatic fever in populations endemic for group A streptococci? ⬇️

scientific article published on June 20, 1998

Cell trafficking. Malaria blood-stage parasite-specific CD4+ T cells after adoptive transfer into mice

scientific article published on January 2002

Cellular interactions of covR/S mutant group A Streptococci

scientific article published on 26 December 2017

Challenges and strategies for developing efficacious and long-lasting malaria vaccines

scientific article published on 01 January 2019

Characterization of the antibody response against Plasmodium falciparum erythrocyte membrane protein 1 in human volunteers

scientific article

Chemical Attenuation in the Development of a Whole-Organism Malaria Vaccine

scientific article

Chemically Attenuated Blood-Stage Plasmodium yoelii Parasites Induce Long-Lived and Strain-Transcending Protection

scientific article published on 31 May 2016

Clones of cytotoxic T lymphocytes reactive to haptenated allogeneic cells: precursor frequency and characteristics as determined by a split-culture approach ⬇️

scientific article published on March 1, 1983

Combinatorial Synthetic Peptide Vaccine Strategy Protects against Hypervirulent CovR/S Mutant Streptococci

scientific article published on 11 March 2016

Comparison of Fluorinated and Nonfluorinated Lipids in Self-Adjuvanting Delivery Systems for Peptide-Based Vaccines

scientific article published on 24 January 2017

Complete protective immunity induced in mice by immunization with the 19-kilodalton carboxyl-terminal fragment of the merozoite surface protein-1 (MSP1[19]) of Plasmodium yoelii expressed in Saccharomyces cerevisiae: correlation of protection with a

scientific article

Conserved T and B cell epitopes on the M protein of group A streptococci. Induction of bactericidal antibodies.

scientific article published in October 1992

Construction of synthetic immunogen: use of new T-helper epitope on malaria circumsporozoite protein

scientific article published in February 1987

Contribution of cryptic epitopes in designing a group A streptococcal vaccine.

scientific article published on 14 June 2018

Controlled Human Malaria Infection: Applications, Advances and Challenges.

scientific article published on 18 September 2017

Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study

scientific article published on 14 May 2019

Controlled infection immunization using delayed death drug treatment elicits protective immune responses to blood-stage malaria parasites

scholarly article published by Leanne M Low in 2018

Correlation between bioluminescence and bacterial burden in passively protected mice challenged with a recombinant bioluminescent M49 group A streptococcus Strain.

scientific article

CpG oligodeoxynucleotide enhances immunity against blood-stage malaria infection in mice parenterally immunized with a yeast-expressed 19 kDa carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (MSP1(19)) formulated in oil-ba

scientific article

Cross-Species Immune Recognition Between Plasmodium vivax Duffy Binding Protein Antibodies and the Plasmodium falciparum Surface Antigen VAR2CSA

scientific article published in 2019

Cross-species malaria immunity induced by chemically attenuated parasites

scientific article

Cryptic epitope for antibodies should not be forgotten in vaccine design.

scientific article

Current Approaches to Group A Streptococcal Vaccine Development

scientific article

Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes

scientific article

Cytotoxic T cells specific for the circumsporozoite protein of plasmodium falciparum

scientific article published in July 1988

Cytotoxic T lymphocyte (CTL) low-responsiveness to the Plasmodium falciparum circumsporozoite protein in naturally-exposed endemic populations: analysis of human CTL response to most known variants

scientific article published in January 1993

Defying malaria: Arming T cells to halt malaria ⬇️

scientific article published on January 1, 2011

Deletion ofPlasmodium berghei-specific CD4+T cells adoptively transferred into recipient mice after challenge with homologous parasite ⬇️

scientific article published on February 17, 1998

Dendritic cell biology during malaria.

scientific article published on 9 January 2007

Design of three-component vaccines against group A streptococcal infections: importance of spatial arrangement of vaccine components.

scientific article published on 28 October 2010

Development and regulation of cell-mediated immune responses to the blood stages of malaria: implications for vaccine research

scientific article

Development of a liposaccharide-based delivery system and its application to the design of group A streptococcal vaccines.

scientific article

Development of a malaria T-cell vaccine for blood stage immunity

scientific article

Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines

scientific article

Development of immunity to malaria may not be an entirely active process

scientific article published on February 1995

Differential non-responsiveness in humans of candidate plasmodium falciparum vaccine antigens

scientific article

Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models

scientific article published on 14 June 2016

Disarming the malaria parasite

scientific article published in September 2008

Double adjuvanting strategy for peptide-based vaccines: trimethyl chitosan nanoparticles for lipopeptide delivery.

scientific article published on 10 November 2016

Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c+ Myeloid Dendritic Cell Maturation Arrest, Induction of the Kynurenine Pathway, and Regulatory T Cell Activation

scientific article

Effect of Plasmodium yoelii exposure on vaccination with the 19-kilodalton carboxyl terminus of merozoite surface protein 1 and vice versa and implications for the application of a human malaria vaccine

scientific article

Effect of initial treatment of chronic inflammatory periodontal disease on the frequency of peripheral blood T-lymphocytes specific to periodontopathic bacteria ⬇️

scientific article published on 01 August 1991

Enhancing Vaccine Efficacy by Engineering a Complex Synthetic Peptide To Become a Super Immunogen

scientific article published on 13 September 2017

Enhancing the immunogenicity and modulating the fine epitope recognition of antisera to a helical group A streptococcal peptide vaccine candidate from the M protein using lipid-core peptide technology

Escaping the immune system: How the malaria parasite makes vaccine development a challenge

scientific article published on 29 October 2013

Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial.

scientific article published on 2 July 2018

Evaluation of the 2-Aminomethylphenol JPC-2997 in Aotus Monkeys Infected with Plasmodium falciparum

scientific article published on 14 December 2015

Evidence implicating MHC genes in the immunological nonresponsiveness to the plasmodium falciparum CS protein

scientific article published on January 1990

Examining cellular immune responses to inform development of a blood-stage malaria vaccine.

scientific article

Experimental asexual blood stage malaria immunity

scientific article published in April 2011

Exploiting the apicoplast: apicoplast-targeting drugs and malaria vaccine development

scientific article published on 26 December 2017

Genetic control of immunity to Plasmodium yoelii sporozoites

scientific article published in December 1989

Genetic control of the immune response in mice to a Plasmodium falciparum sporozoite vaccine. Widespread nonresponsiveness to single malaria T epitope in highly repetitive vaccine

scientific article

Genetic regulation of protective immune response in congenic strains of mice vaccinated with a subunit malaria vaccine.

scientific article published in August 1996

Genetic restriction of protective immunity to Plasmodium yoelii sporozoites.

scientific article published on January 1990

Genetically modified Plasmodium highlights the potential of whole parasite vaccine strategies

scientific article published in 2005

Geographically restricted heterogeneity of the Plasmodium falciparum circumsporozoite protein: relevance for vaccine development

scientific article published on February 1992

Gold(i) phosphine compounds as parasite attenuating agents for malaria vaccine and drug development

scientific article published on 21 February 2018

Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity

scientific article published on December 2014

Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct.

scientific article

Heterologous immunity in the absence of variant-specific antibodies after exposure to subpatent infection with blood-stage malaria

scientific article

High frequency of malaria-specific T cells in non-exposed humans

scientific article published on March 1992

Highly Immunogenic Trimethyl Chitosan-based Delivery System for Intranasal Lipopeptide Vaccines against Group A Streptococcus

scientific article published on 21 July 2016

Human T cell recognition of polymorphic epitopes from malaria circumsporozoite protein

scientific article published in June 1989

Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria

scientific article published on 07 June 2009

Human T clones reactive to the sexual stages of plasmodium falciparum malaria. high frequency of gamete-reactive T cells in peripheral blood from nonexposed donors

scientific article published in January 1987

Human T-cell recognition of the circumsporozoite protein of plasmodium falciparum: Immunodominant T-cell domains map to the polymorphic regions of the molecule

scientific article

Human T-cell responses to malaria: mostly forgotten or committed to memory?

scientific article published in August 1994

Human and murine CD4 T cell epitopes map to the same region of the malaria circumsporozoite protein: Limited immunogenicity of sporozoites and circumsporozoite protein

scientific article published in December 1988

Human and murine T-cell responses to allelic forms of a malaria circumsporozoite protein epitope support a polyvalent vaccine strategy

scientific article published on July 1998

Human antibodies to the conserved region of the M protein: opsonization of heterologous strains of group A streptococci ⬇️

scientific article published on 01 November 1997

Humanized Mouse Models to Study Cell-Mediated Immune Responses to Liver-Stage Malaria Vaccines

scientific article published on 09 October 2015

Identification of Caucasian CD4 T cell epitopes on the circumsporozoite protein of Plasmodium vivax. T cell memory ⬇️

scientific article published on July 15, 1993

Identification of T cell autoepitopes that cross-react with the C-terminal segment of the M protein of group A streptococci

scientific article published on August 1994

Identification of T cell epitopes on the 33-kDa fragment of Plasmodium yoelii merozoite surface protein 1 and their antibody-independent protective role in immunity to blood stage malaria

scientific article published on July 2002

Identification of early cellular immune factors regulating growth of malaria parasites in humans

scientific article

Immune effector mechanisms in malaria

scientific article

Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria

scientific article published on 18 August 2010

Immunity to Sexual Stages of Malaria Parasites

scholarly article by Richard Carter et al published 1988 in Chemical Immunology and Allergy

Immunity to Sexual Stages of Malaria Parasites

scholarly article published in Chemical Immunology and Allergy

Immunity to asexual blood stage malaria and vaccine approaches

scientific article

Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum

scientific article

Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcus

scientific article published on 10 May 2006

Immunogenicity in mice and non-human primates of the Group A Streptococcal J8 peptide vaccine candidate conjugated to CRM197.

scientific article published on 18 December 2012

Immunoglobulin G3 antibodies specific for the 19-kilodalton carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein 1 transfer protection to mice deficient in Fc-gammaRI receptors

scientific article

Immunological Impediments to Developing a Blood Stage Malaria Vaccine

scholarly article by Michelle Wykes et al published 1 November 2006 in Current Immunology Reviews

Immunological evaluation of lipopeptide group A streptococcus (GAS) vaccine: structure-activity relationship

scientific article

Immunological response to parenteral vaccination with recombinant hepatitis B virus surface antigen virus-like particles expressing Helicobacter pylori KatA epitopes in a murine H. pylori challenge model.

scientific article published on 28 December 2011

Immunological responses from non-exposed donors to malaria antigens: implications for immunity and pathology

scientific article published on July 1994

Immunology. Pasteur approach to a malaria vaccine may take the lead

scientific article published in September 2013

Immunology. Platelets kill the parasite within

scientific article published in December 2012

In vivo efficacy of a chimeric peptide derived from the conserved region of the M protein against group C and G streptococci

scientific article published on 17 October 2012

In vivo testing of subunit vaccines against malaria sporozoites using a rodent system

scientific article

Inability of Plasmodium vinckei-immune spleen cells to transfer protection to recipient mice exposed to vaccine‘vectors’or heterologous species of plasmodium ⬇️

scientific article published on September 1, 1991

Increased immunoreactivity to two overlapping peptides of myelin proteolipid protein in multiple sclerosis ⬇️

scientific article published on August 1, 1997

Induction of Plasmodium-Specific Immune Responses Using Liposome-Based Vaccines

article

Induction of anti-Plasmodium immunity following subpatent infection with live erythrocytic stages and drug cure

scientific article published in January 2013

Induction of autoimmune valvulitis in Lewis rats following immunization with peptides from the conserved region of group A streptococcal M protein

scientific article published on 01 May 2003

Induction of immunity following vaccination with a chemically attenuated malaria vaccine correlates with persistent antigenic stimulation.

scientific article

Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite

scientific article published on 05 July 2016

Inhibition of 19-kDa C-terminal region of merozoite surface protein-1-specific antibody responses in neonatal pups by maternally derived 19-kDa C-terminal region of merozoite surface protein-1-specific antibodies but not whole parasite-specific anti

scientific article published in May 2004

Inhibition of Plasmodium falciparum growth in vitro by CD4+ and CD8+ T cells from non-exposed donors

scientific article published in November 1994

Interactions between malaria parasites and the host immune system

scientific article

Interdependence of CD4+ T cells and malarial spleen in immunity to Plasmodium vinckei vinckei. Relevance to vaccine development

scientific article published in September 1989

Interpreting challenge data from early phase malaria blood stage vaccine trials

scientific article published on 30 January 2018

Intranasal Vaccination with a Lipopeptide Containing a Conformationally Constrained Conserved Minimal Peptide, a Universal T Cell Epitope, and a Self‐Adjuvanting Lipid Protects Mice from Group A Streptococcus Challenge and Reduces Throat Colonizati

scientific article published on 20 June 2006

Intranasal administration is an effective mucosal vaccine delivery route for self-adjuvanting lipid core peptides targeting the group A streptococcal M protein.

scientific article

Intranasal immunization with yeast-expressed 19 kD carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (yMSP119) induces protective immunity to blood stage malaria infection in mice

scientific article published in September 1998

Intranasal vaccination with a lipopeptide containing a minimal, conserved M-protein derived peptide and a self-adjuvanting lipid induces both systemic and mucosal immune responses in mice

article

Investigation of group A Streptococcus immune responses in an endemic setting, with a particular focus on J8

article

Involvement of T cells in malaria immunity: implications for vaccine development

scientific article published on February 1989

Lack of cross-reactivity between variant T cell determinants from malaria circumsporozoite protein

scientific article

Lengthy antimalarial activity of atovaquone in human plasma following atovaquone-proguanil administration

scientific article published on October 2005

Limited immunological recognition of critical malaria vaccine candidate antigens

scientific article published in October 1988

Linear and branched polyacrylates as a delivery platform for peptide-based vaccines.

scientific article published in September 2016

Lipid core peptide/poly(lactic-co-glycolic acid) as a highly potent intranasal vaccine delivery system against Group A streptococcus

scientific article

Lipoamino acid-based adjuvant carrier system: enhanced immunogenicity of group a streptococcal peptide epitopes

scientific article published on 01 March 2002

Liposome-based intranasal delivery of lipopeptide vaccine candidates against group A streptococcus

scientific article published on 7 April 2016

Location of human cytotoxic T cell epitopes within a polymorphic domain of the Plasmodium falciparum circumsporozoite protein

scientific article

Long-term antibody memory induced by synthetic peptide vaccination is protective against Streptococcus pyogenes infection and is independent of memory T cell help.

scientific article published on 11 February 2013

Low doses of killed parasite in CpG elicit vigorous CD4+ T cell responses against blood-stage malaria in mice.

scientific article

Low-level Plasmodium falciparum blood-stage infection causes dendritic cell apoptosis and dysfunction in healthy volunteers.

scientific article published on 21 May 2012

M-protein-derived conformational peptide epitope vaccine candidate against Group A Streptococcus.

scientific article published in February 2013

Major population differences in T cell response to a malaria sporozoite vaccine candidate

scientific article published on January 1990

Malaria Vaccines

scholarly article by Michael F. Good et al published 1992 in Biotechnology (Reading, Mass.)

Malaria parasite-specific Th1-like T cells simultaneously reduce parasitemia and promote disease

scientific article

Malaria parasites up close

scientific article published in February 2006

Malaria pathogenesis

scientific article published on June 1994

Malaria vaccine design: immunological considerations

scientific article published on October 2010

Malaria vaccine development: recent progress towards a sporozoite vaccine

scientific article published on September 1990

Malaria vaccine developments

scientific article published on January 2004

Malaria vaccine research: lessons from 2008/9.

scientific article published on August 2009

Malaria vaccines: New hope in old ideas

scholarly article by Alberto Pinzon-Charry et al published June 2006 in Drug Discovery Today: Therapeutic Strategies

Malaria vaccines: the case for a whole-organism approach

scientific article published in April 2008

Malaria's journey through the lymph node

scientific article published in September 2007

Malaria. Tying the conductor's arms

scientific article

Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice

scientific article published on 19 December 2019

Mechanism of protection induced by group A Streptococcus vaccine candidate J8-DT: contribution of B and T-cells towards protection

scientific article

Memory B cell responses and malaria.

scientific article

Method for the synthesis of highly pure vaccines using the lipid core peptide system

scientific article published on 01 December 2006

Method for the synthesis of multi-epitopic Streptococcus pyogenes lipopeptide vaccines using native chemical ligation

scientific article published on 01 September 2006

Mixed results for a malaria vaccine

scientific article published on 6 December 2011

Multilayer engineered nanoliposomes as a novel tool for oral delivery of lipopeptide-based vaccines against group A Streptococcus.

scientific article published on 14 April 2016

Nanovaccines and their mode of action.

scientific article published on 24 April 2013

Nature and specificity of the required protective immune response that develops postchallenge in mice vaccinated with the 19-kilodalton fragment of Plasmodium yoelii merozoite surface protein 1.

scientific article

Neonatal exposure to immunogenic peptides. Differential susceptibility to tolerance induction of helper T cells and B cells reactive to malarial circumsporozoite peptide epitopes.

scientific article published in May 1988

Novel platform technology for modular mucosal vaccine that protects against streptococcus.

scientific article published on 15 December 2016

Our impasse in developing a malaria vaccine ⬇️

scientific article published on February 15, 2011

PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria.

scientific article

Parasite polymorphism present within minimal T cell epitopes of Plasmodium falciparum circumsporozoite protein

scientific article published on 01 March 1988

Pathways and strategies for developing a malaria blood-stage vaccine

scientific article published in January 1998

Peptide analysis of the T cell response to the malaria circumsporozoite (CS) protein

scientific article published on August 1990

Peptide immunization can elicit malaria protein-specific memory helper but not proliferative T cells.

scientific article published in May 1990

Persistence and immunogenicity of chemically attenuated blood stage Plasmodium falciparum in Aotus monkeys

scientific article published on 26 May 2016

Physicochemical characterisation, immunogenicity and protective efficacy of a lead streptococcal vaccine: progress towards Phase I trial

scientific article published on 23 October 2017

Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation

scientific article

Plasmodium berghei bio-burden correlates with parasite lactate dehydrogenase: application to murine Plasmodium diagnostics

scientific article

Plasmodium falciparum-specific T cell clones from non-exposed and exposed donors are highly diverse in TCR beta chain V segment usage

scientific article published in December 1996

Plasmodium strain determines dendritic cell function essential for survival from malaria

scientific article

Plasmodium yoelii can ablate vaccine-induced long-term protection in mice

scientific article published in August 2005

Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

scientific article published on 29 January 2020

Polyacrylate Dendrimer Nanoparticles: A Self-Adjuvanting Vaccine Delivery System

scientific article published on 01 August 2010

Polyacrylate-based delivery system for self-adjuvanting anticancer peptide vaccine.

scientific article published on 22 December 2014

Polyglutamic acid-trimethyl chitosan-based intranasal peptide nano-vaccine induces potent immune responses against group A streptococcus

scientific article published on 25 September 2018

Polymer-peptide hybrids as a highly immunogenic single-dose nanovaccine.

scientific article published on 23 April 2013

Polymorphism in the circumsporozoite (CS) protein of Plasmodium falciparum

scientific article published in May 1989

Polyspecific malaria antibodies present at the time of infection inhibit the development of immunity to malaria but antibodies specific for the malaria merozoite surface protein, MSP1, facilitate immunity

scientific article published in May 2002

Potential of lipid core peptide technology as a novel self-adjuvanting vaccine delivery system for multiple different synthetic peptide immunogens.

scientific article

Preclinical evaluation of a vaccine based on conserved region of M protein that prevents group A streptococcal infection

scientific article

Preclinical immunogenicity and safety of a Group A streptococcal M protein-based vaccine candidate.

scientific article

Profoundly Reduced CD1c+ Myeloid Dendritic Cell HLA-DR and CD86 Expression and Increased Tumor Necrosis Factor Production in Experimental Human Blood-Stage Malaria Infection

scientific article published on 22 February 2016

Promiscuous malaria peptide epitope stimulates CD45Ra T cells from peripheral blood of nonexposed donors

scientific article published in February 1992

Prospective surveillance of invasive group a streptococcal disease, Fiji, 2005-2007.

scientific article published on February 2009

Prospective surveillance of streptococcal sore throat in a tropical country

scientific article

Prospects for a vaccine against malaria

scientific article published on April 2002

Protection of mice from group A streptococcal infection by intranasal immunisation with a peptide vaccine that contains a conserved M protein B cell epitope and lacks a T cell autoepitope

scientific article published on June 2002

Protection of rats against malaria by a transplanted immune spleen

scientific article published in July 1996

Protection of sheep against bovine leukemia virus (BLV) infection by vaccination with recombinant vaccinia viruses expressing BLV envelope glycoproteins: correlation of protection with CD4 T-cell response to gp51 peptide 51-70 ⬇️

scientific article published on April 1, 1993

Protein antigenic structures recognized by T cells: potential applications to vaccine design

scientific article published on August 1987

Recognition of dominant T cell-stimulating epitopes from the circumsporozoite protein of Plasmodium falciparum and relationship to malaria morbidity in Gambian children

scientific article published in September 1990

Recombinant human IL-2 overcomes genetic nonresponsiveness to malaria sporozoite peptides. Correlation of effect with biologic activity of IL-2.

scientific article published in August 1988

Research toward malaria vaccines

scientific article

Restricted or absent immune responses in human populations to plasmodium falciparum gamete antigens that are targets of malaria transmission-blocking antibodies

scientific article

Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice

scientific article

Role of intrastructural/intermolecular help in immunization with peptide-phospholipid complexes

scientific article published on 01 July 1991

Self-adjuvanting modular virus-like particles for mucosal vaccination against group A streptococcus (GAS).

scientific article published on 17 February 2013

Self-adjuvanting polyacrylic nanoparticulate delivery system for group A streptococcus (GAS) vaccine

scientific article published on 27 October 2010

Self-adjuvanting vaccine against group A streptococcus: application of fibrillized peptide and immunostimulatory lipid as adjuvant.

scientific article

Single-chain antibodies produced by phage display against the C-terminal 19 kDa region of merozoite surface protein-1 of Plasmodium yoelii reduce parasite growth following challenge

scientific article

Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group a streptococcal vaccines

scientific article published on 18 April 2014

Skin infection boosts memory B-cells specific for a cryptic vaccine epitope of group A streptococcus and broadens the immune response to enhance vaccine efficacy.

scientific article

Soluble CD38 significantly prolongs the lifespan of memory B-cell responses

scientific article published in September 2008

Status of research and development of vaccines for Streptococcus pyogenes

scientific article

Strategic development of the conserved region of the M protein and other candidates as vaccines to prevent infection with group A streptococci

scientific article

Strategies in the development of vaccines to prevent infections with group A streptococcus

scientific article

Streptococcal Immunity Is Constrained by Lack of Immunological Memory following a Single Episode of Pyoderma.

scientific article

Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes.

scientific article published on 25 September 2012

Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group a streptococcal vaccine candidates

scientific article published on 12 December 2007

Summary of the meeting on cellular mechanisms in malaria immunity

scientific article published in August 1990

Synthesis and immunological evaluation of self-adjuvanting glycolipopeptide vaccine candidates

scientific article

Synthesis and in vivo studies of carbohydrate-based vaccines against group A streptococcus.

scientific article published in January 2008

Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A streptococcal vaccine, and subsequent immunological evaluation

scientific article published on 01 October 2006

Synthesis, Characterization and Immunological Evaluation of Self-Adjuvanting Group A Streptococcal Vaccine Candidates Bearing Various Lipidic Adjuvanting Moieties

scientific article published on 11 January 2017

Synthetic peptides from P.falciparum sexual stage 25-kDa protein induce antibodies that react with the native protein: The role of IL-2 and conformational structure on immunogenicity of Pfs25

scientific article published in November 1995

Systemic tumor necrosis factor generated during lethal Plasmodium infections impairs dendritic cell function

scientific article

T cells, T sites, and malaria immunity--further optimism for vaccine development

scientific article published on March 1988

T-cell antigenic sites of the malaria circumsporozoite protein.

scientific article

T-cell responses to highly conserved CD4 and CD8 epitopes on the outer membrane protein of bovine leukemia virus: relevance to vaccine development ⬇️

scientific article published on April 1, 1993

The 230-kDa gamete surface protein of plasmodium falciparum is also a target for transmission-blocking antibodies

scientific article published in December 1987

The Immune Response to Asexual Blood Stages of Malaria Parasites ⬇️

scientific article published on January 1, 1998

The Impact of Established Immunoregulatory Networks on Vaccine Efficacy and the Development of Immunity to Malaria.

scientific article published on December 2016

The Role of Size in Development of Mucosal Liposome-Lipopeptide Vaccine Candidates Against Group A Streptococcus

scientific article published on 19 July 2016

The T cell response to the malaria circumsporozoite protein: an immunological approach to vaccine development

scientific article

The ability to inoculate purified malaria sporozoites will accelerate vaccine and drug discovery.

scientific article published on 28 July 2014

The hope but challenge for developing a vaccine that might control malaria

scientific article published in April 2009

The immunologic significance of variation within malaria circumsporozoite protein sequences

scientific article published on May 1989

The immunological challenge to developing a vaccine to the blood stages of malaria parasites.

scientific article published in October 2004

The implications for malaria vaccine programs if memory T cells from non-exposed humans can respond to malaria antigens ⬇️

scientific article published on August 1, 1991

The importance of T cell homing and the spleen in reaching a balance between malaria immunity and immunopathology: the moulding of immunity by early exposure to cross-reactive organisms

scientific article

The main obstacle to a malaria vaccine: the malaria parasite

scientific article published on April 1988

The mechanism and significance of deletion of parasite-specific CD4(+) T cells in malaria infection

scientific article

The need for assays predictive of protection in development of malaria bloodstage vaccines

scientific article

The purine salvage enzyme hypoxanthine guanine xanthine phosphoribosyl transferase is a major target antigen for cell-mediated immunity to malaria

scholarly article

The quest for GAS vaccine

scientific article published on 16 October 2015

The real difficulties for malaria sporozoite vaccine development: nonresponsiveness and antigenic variation

scientific article published on November 1988

The relevance of non-human primate and rodent malaria models for humans

scientific article

The role of the 19-kDa region of merozoite surface protein 1 and whole-parasite-specific maternal antibodies in directing neonatal pups' responses to rodent malaria infection

scientific article published in November 2003

Toward the development of a synthetic group a streptococcal vaccine of high purity and broad protective coverage

scientific article published on 01 July 2004

Towards a blood-stage vaccine for malaria: are we following all the leads?

scientific article

Towards a vaccine for rheumatic fever: identification of a conserved target epitope on M protein of group A streptococci ⬇️

scientific article published on September 3, 1994

Towards the development of the ideal malaria vaccine. A decade of progress in a difficult field.

scientific article published on February 1991

Vaccination against rheumatic heart disease: a review of current research strategies and challenges

scientific article published on August 2012

Vaccination with chemically attenuated Plasmodium falciparum asexual blood-stage parasites induces parasite-specific cellular immune responses in malaria-naïve volunteers: a pilot study

article

Vaccine delivery utilizing liposaccharides

scientific article published on 01 January 2009

Vaccine delivery: synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate.

scientific article published in January 2009

Vaccine-induced cytotoxic T lymphocytes protect against retroviral challenge ⬇️

scientific article published on October 1, 1998

Vaccine-induced immunity to malaria parasites and the need for novel strategies

scientific article

What have we learnt from mouse models for the study of malaria?

scientific article published in August 2009

What really happens to dendritic cells during malaria?

scientific article published on 19 August 2008

Whole organism blood stage vaccines against malaria

scientific article published on 28 September 2015

Whole parasite blood stage malaria vaccines: a convergence of evidence

scientific article published on 21 January 2010

Whole parasite vaccines for the asexual blood stages of Plasmodium

scientific article published on 10 November 2019

emm and C-repeat region molecular typing of beta-hemolytic Streptococci in a tropical country: implications for vaccine development

scientific article published on 10 June 2009

Paulina is supported by:

About Paulina

Help