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List of works by Jean-Charles Portais

A methodology for the validation of isotopic analyses by mass spectrometry in stable-isotope labelling experiments

scientific article published on 20 December 2017

A novel platform for automated high-throughput fluxome profiling of metabolic variants.

scientific article published on 12 June 2014

Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle and to proline metabolism.

scientific article published on 11 August 2010

Acetate Exposure Determines the Diauxic Behavior of Escherichia coli during the Glucose-Acetate Transition.

scientific article

Acetate fluxes in Escherichia coli are determined by the thermodynamic control of the Pta-AckA pathway.

scientific article published on 10 February 2017

An optimization method for untargeted MS-based isotopic tracing investigations of metabolism

scientific article published in 2022

Application of 2D-TOCSY NMR to the measurement of specific(13C-enrichments in complex mixtures of 13C-labeled metabolites.

scientific article published on 16 March 2007

Bio-based succinate from sucrose: High-resolution 13C metabolic flux analysis and metabolic engineering of the rumen bacterium Basfia succiniciproducens.

scientific article

Biofilm microenvironment induces a widespread adaptive amino-acid fermentation pathway conferring strong fitness advantage in Escherichia coli.

scientific article

Carbohydrate cycling in micro-organisms: what can (13)C-NMR tell us?

scientific article

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

scientific article published on 17 April 2017

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.

scientific article

Co-consumption of methanol and succinate by Methylobacterium extorquens AM1.

scientific article

Combined transcriptomics-metabolomics profiling of the heat shock response in the hyperthermophilic archaeon Pyrococcus furiosus

scientific article published on 14 November 2018

Combining metabolomics and gene expression analysis reveals that propionyl- and butyryl-carnitines are involved in late stages of arbuscular mycorrhizal symbiosis.

scientific article published on 11 October 2013

Comparative analysis of 13C-enriched metabolites released in the medium of cerebellar and cortical astrocytes incubated with [1-13C]glucose

scientific article published on 01 August 1995

Control and regulation of acetate overflow in Escherichia coli

scientific article published in 2021

Correction of MS data for naturally occurring isotopes in isotope labelling experiments.

scientific article

Cyclic organization of the carbohydrate metabolism in Sinorhizobium meliloti

scientific article published on 01 October 1999

Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux.

scientific article published on 10 May 2013

Demonstration of the ethylmalonyl-CoA pathway by using 13C metabolomics.

scholarly article

Determination of carbon labeling distribution of intracellular metabolites from single fragment ions by ion chromatography tandem mass spectrometry.

scientific article

Developmental stage dependent metabolic regulation during meiotic differentiation in budding yeast.

scientific article

Differential quantitative proteome analysis of Escherichia coli grown on acetate versus glucose.

scientific article published on 08 September 2016

E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity

scientific article published on 12 September 2016

Engineering Escherichia coli for methanol conversion

scientific article published on 14 January 2015

Exploring the Glucose Fluxotype of the E. coli y-ome Using High-Resolution Fluxomics

scientific article published in 2021

Fast spatially encoded 3D NMR strategies for (13)C-based metabolic flux analysis

scientific article published on 24 September 2013

FindPath: a Matlab solution for in silico design of synthetic metabolic pathways.

scientific article published on 3 July 2014

Functional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling

scientific article published on 21 August 2019

Functional characterization of a gene locus from an uncultured gut Bacteroides conferring xylo-oligosaccharides utilization to Escherichia coli.

scientific article

Functional genomics of the muscle response to restraint and transport in chickens.

scientific article published on 21 April 2011

Genome-scale reconstruction and system level investigation of the metabolic network of Methylobacterium extorquens AM1.

scientific article

Gluconeogenesis is essential for trypanosome development in the tsetse fly vector

scientific article published on 17 December 2018

Glucose and glutamine metabolism in C6 glioma cells studied by carbon 13 NMR.

scientific article published in January 1996

Glutathione, but not glutamine, is detected in 13C-NMR spectra of perchloric acid extracts from C6 glioma cells.

scientific article published in August 1993

Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions

scientific article published on 01 November 2018

Glycerol suppresses glucose consumption in trypanosomes through metabolic contest

scientific article published on 13 August 2021

High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells

scientific article published on 10 March 2017

Identification of a fourth formate dehydrogenase in Methylobacterium extorquens AM1 and confirmation of the essential role of formate oxidation in methylotrophy.

scientific article published on 05 October 2007

Impact of kinetic isotope effects in isotopic studies of metabolic systems.

scientific article published on 26 September 2015

Improved Isotopic Profiling by Pure Shift Heteronuclear 2D J-Resolved NMR Spectroscopy

scientific article published on 06 March 2018

Improved riboflavin production with Ashbya gossypii from vegetable oil based on 13C metabolic network analysis with combined labeling analysis by GC/MS, LC/MS, 1D, and 2D NMR.

scientific article published on 11 April 2018

In vivo 13C NMR determines metabolic fluxes and steady state in linseed embryos

scientific article published on 30 May 2007

In vivo 13C-NMR studies of polymer synthesis in rhizobium meliloti M5N1 strain

In-cell NMR: from metabolites to macromolecules

scientific article published on 15 January 2018

IsoCor: correcting MS data in isotope labeling experiments.

scientific article

IsoDesign: A software for optimizing the design of 13C‐metabolic flux analysis experiments ⬇️

scientific article published on September 18, 2013

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia.

scientific article published on 7 March 2016

Isotopic profiling of 13C-labeled biological samples by two-dimensional heteronuclear J-resolved nuclear magnetic resonance spectroscopy ⬇️

scientific article published on May 29, 2012

Isotopic studies of metabolic systems by mass spectrometry: using Pascal's triangle to produce biological standards with fully controlled labeling patterns

scientific article published on 2 October 2014

Lysine production from the sugar alcohol mannitol: Design of the cell factory Corynebacterium glutamicum SEA-3 through integrated analysis and engineering of metabolic pathway fluxes

scientific article published on 27 April 2018

Magnetic resonance spectroscopy and metabolism. Applications of proton and 13C NMR to the study of glutamate metabolism in cultured glial cells and human brain in vivo.

scientific article published on January 1991

Mechanism of gluconate synthesis in Rhizobium meliloti by using in vivo NMR

scientific article published on 01 August 1997

Metabolic flux analysis in Ashbya gossypii using C-labeled yeast extract: industrial riboflavin production under complex nutrient conditions

article

Metabolic footprint of epiphytic bacteria on Arabidopsis thaliana leaves

scientific article published on 25 August 2015

Metabolite profiling of pea roots in response to phosphate availability.

scientific article published on June 2011

Mitochondrial energetic and AKT status mediate metabolic effects and apoptosis of metformin in human leukemic cells.

scientific article published on 9 April 2013

Multilevel interaction of the DnaK/DnaJ(HSP70/HSP40) stress-responsive chaperone machine with the central metabolism.

scientific article published on 27 January 2017

NMR-based fluxomics: quantitative 2D NMR methods for isotopomers analysis.

scientific article published on 26 April 2007

Photobioreactor design for isotopic non‐stationary 13C‐metabolic flux analysis (INST 13C‐MFA) under photoautotrophic conditions ⬇️

scientific article published on June 27, 2012

Physiological and Molecular Timing of the Glucose to Acetate Transition in Escherichia coli

scientific article published on 20 September 2013

Plasmid-encoded biosynthetic genes alleviate metabolic disadvantages while increasing glucose conversion to shikimate in an engineered Escherichia coli strain

scientific article published on 10 February 2017

Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline

scientific article published on 01 March 2021

Production of carbon-13-labeled cadaverine by engineered Corynebacterium glutamicum using carbon-13-labeled methanol as co-substrate.

scientific article

Quantitative metabolome analysis using liquid chromatography-high-resolution mass spectrometry.

scientific article published on 18 July 2008

Quantitative metabolomics of the thermophilic methylotroph Bacillus methanolicus

scientific article

Recent advances in high-throughput 13C-fluxomics

scientific article published on 10 November 2016

Relevance and isotopic assessment of hexose-6-phosphate recycling in micro-organisms

scientific article published on 01 January 2000

Response of the central metabolism of Escherichia coli to modified expression of the gene encoding the glucose-6-phosphate dehydrogenase.

scientific article published on 3 July 2007

Sampling for metabolome analysis of microorganisms.

scientific article published on 6 April 2007

Sampling of intracellular metabolites for stationary and non-stationary (13)C metabolic flux analysis in Escherichia coli.

scientific article

ScalaFlux: A scalable approach to quantify fluxes in metabolic subnetworks

scientific article published on 14 April 2020

Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia

scientific article published on 25 October 2018

Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments.

scientific article

Strigolactones stimulate arbuscular mycorrhizal fungi by activating mitochondria

scientific article

Synthesis of dextrans with controlled amounts of alpha-1,2 linkages using the transglucosidase GBD-CD2.

scientific article published on 16 October 2009

Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma

scientific article published on 01 June 2020

The Csr System Regulates Escherichia coli Fitness by Controlling Glycogen Accumulation and Energy Levels

scientific article published on 31 October 2017

The carbon storage regulator (Csr) system exerts a nutrient-specific control over central metabolism in Escherichia coli strain Nissle 1917.

scientific article

The ethylmalonyl-CoA pathway is used in place of the glyoxylate cycle by Methylobacterium extorquens AM1 during growth on acetate.

scientific article published on 21 November 2011

The post-transcriptional regulatory system CSR controls the balance of metabolic pools in upper glycolysis of Escherichia coli.

scientific article published on 2 February 2016

Theoretical Basis for Dynamic Label Propagation in Stationary Metabolic Networks under Step and Periodic Inputs.

scientific article published on 7 December 2015

Transketolase in Trypanosoma brucei

scientific article published on 12 May 2011

UFJCOSY: a fast 3D NMR method for measuring isotopic enrichments in complex samples

scientific article published on 26 June 2012

Ultrafast quantitative 2D NMR: an efficient tool for the measurement of specific isotopic enrichments in complex biological mixtures.

scientific article

[1-13C]glucose metabolism in rat cerebellar granule cells and astrocytes in primary culture. Evaluation of flux parameters by 13C- and 1H-NMR spectroscopy

scientific article published on 01 October 1993

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