List of works - Jennifer Lodge

A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome.

scientific article

A glycosylphosphatidylinositol anchor is required for membrane localization but dispensable for cell wall association of chitin deacetylase 2 in Cryptococcus neoformans.

scientific article published on 21 February 2012

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation

scientific article

Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans.

scientific article published on 22 July 2011

Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans.

scientific article published on October 2005

Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans.

scientific article published on 30 March 2007

Cross talk between the cell wall integrity and cyclic AMP/protein kinase A pathways in Cryptococcus neoformans

scientific article

Cryptococcus at work: gene expression during human infection

scientific article published on 22 April 2014

Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

scientific article published on 20 November 2018

Cryptococcus neoformans Phosphoinositide-Dependent Kinase 1 (PDK1) Ortholog Is Required for Stress Tolerance and Survival in Murine Phagocytes ⬇️

scientific article published on October 19, 2012

Cryptococcus neoformans, a fungus under stress

scientific article published on 17 August 2007

Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifung

scientific article published on August 1997

Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1

scientific article

Erratum for Attarian et al., "The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans"

scientific article published on 30 April 2019

Function of the thioredoxin proteins in Cryptococcus neoformans during stress or virulence and regulation by putative transcriptional modulators.

scientific article published in August 2005

Galactose-Inducible promoters in Cryptococcus neoformans var. grubii

scientific article published on 01 January 2012

Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent.

scientific article

Global transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stress

scientific article

Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: absence of Ku proteins increases homologous recombination, and co-transformation of independent DNA molecules allows rapid complementation of deletion phenotypes

scientific article published on 22 May 2006

Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of Cryptococcus neoformans.

scientific article published on 10 May 2016

Isocitrate dehydrogenase is important for nitrosative stress resistance in Cryptococcus neoformans, but oxidative stress resistance is not dependent on glucose-6-phosphate dehydrogenase.

scientific article published on 16 April 2010

Mechanisms of resistance to oxidative and nitrosative stress: implications for fungal survival in mammalian hosts

scientific article published in August 2004

Melanin deposition in two Cryptococcus species depends on cell-wall composition and flexibility

scientific article published on 02 January 2020

Multiple Gene Deletion in Cryptococcus neoformans Using the Cre–lox System ⬇️

scientific article published on January 1, 2012

N-myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA: protein N-myristoyltransferase

scientific article published on 01 February 1997

Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts.

scientific article

Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 Signaling Pathway in Response to Thermal Stress ⬇️

scientific article published on November 16, 2012

Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway in Cryptococcus neoformans and contributes to fungal virulence.

scientific article published on 03 October 2013

Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival

scientific article

Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.

scientific article

The Cryptococcus neoformans genome sequencing project.

scientific article

The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans

scientific article published on 04 December 2018

The second amino acid of alfalfa mosaic virus coat protein is critical for coat protein-mediated protection.

scientific article published on March 1991

Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans

scientific article

Tn5 insertion specificity is not influenced by IS50 end sequences in target DNA

scientific article published on 01 August 1991

Two glutathione peroxidases in the fungal pathogen Cryptococcus neoformans are expressed in the presence of specific substrates.

scientific article published in August 2005

Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species.

scientific article

List of works by Jennifer Lodge

A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome.

A glycosylphosphatidylinositol anchor is required for membrane localization but dispensable for cell wall association of chitin deacetylase 2 in Cryptococcus neoformans.

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation

Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans.

Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans.

Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans.

Cross talk between the cell wall integrity and cyclic AMP/protein kinase A pathways in Cryptococcus neoformans

Cryptococcus at work: gene expression during human infection

Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

Cryptococcus neoformans Phosphoinositide-Dependent Kinase 1 (PDK1) Ortholog Is Required for Stress Tolerance and Survival in Murine Phagocytes ⬇️

Cryptococcus neoformans, a fungus under stress

Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifung

Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1

Erratum for Attarian et al., "The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans"

Function of the thioredoxin proteins in Cryptococcus neoformans during stress or virulence and regulation by putative transcriptional modulators.

Galactose-Inducible promoters in Cryptococcus neoformans var. grubii

Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent.

Global transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stress

Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans: absence of Ku proteins increases homologous recombination, and co-transformation of independent DNA molecules allows rapid complementation of deletion phenotypes

Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of Cryptococcus neoformans.

Isocitrate dehydrogenase is important for nitrosative stress resistance in Cryptococcus neoformans, but oxidative stress resistance is not dependent on glucose-6-phosphate dehydrogenase.

Mechanisms of resistance to oxidative and nitrosative stress: implications for fungal survival in mammalian hosts

Melanin deposition in two Cryptococcus species depends on cell-wall composition and flexibility

Multiple Gene Deletion in Cryptococcus neoformans Using the Cre–lox System ⬇️

N-myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA: protein N-myristoyltransferase

Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts.

Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 Signaling Pathway in Response to Thermal Stress ⬇️

Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway in Cryptococcus neoformans and contributes to fungal virulence.

Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival

Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.

The Cryptococcus neoformans genome sequencing project.

The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans

The second amino acid of alfalfa mosaic virus coat protein is critical for coat protein-mediated protection.

Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans

Tn5 insertion specificity is not influenced by IS50 end sequences in target DNA

Two glutathione peroxidases in the fungal pathogen Cryptococcus neoformans are expressed in the presence of specific substrates.

Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species.