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List of works by Alain Eychène

A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation.

scientific article

A new MAFia in cancer.

scientific article published on September 2008

Activation of ERK, controlled by Rac1 and Cdc42 via Akt, is required for anoikis

scientific article published on 01 November 2002

Alternative splicing in oncogenic kinases: from physiological functions to cancer

scientific article

An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma

scientific article published on 22 July 2019

B-Raf and C-Raf are required for melanocyte stem cell self-maintenance

scientific journal article

B-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouse

scientific article

B-raf gene encodes for multiple isoforms with Mek-1 kinase activity

scientific article published on January 1, 1995

BRAF as a melanoma susceptibility candidate gene?

scientific article published in June 2003

Cell context reveals a dual role for Maf in oncogenesis.

scientific article

Chromosomal assignment of two human B-raf(Rmil) proto-oncogene loci: B-raf-1 encoding the p94Braf/Rmil and B-raf-2, a processed pseudogene.

scientific article

Common mechanism of retrovirus activation and transduction of c-mil and c-Rmil in chicken neuroretina cells infected with Rous-associated virus type 1.

scientific article published on July 1991

Comparison of maf gene expression patterns during chick embryo development.

scientific article published in January 2004

GSK-3-mediated phosphorylation enhances Maf-transforming activity

scientific journal article

GSK3-mediated MAF phosphorylation in multiple myeloma as a potential therapeutic target

scientific article published on 17 January 2014

MB-09AGGRESSIVE MEDULLOBLASTOMA SUBVERTS THE PHOTORECEPTOR SPECIFIC TRANSCRIPTION FACTOR NRL.

scientific article published on 21 April 2015

MITF activity is regulated by a direct interaction with RAF proteins in melanoma cells

scientific article published on 28 January 2022

MafA transcription factor identifies the early ret-expressing sensory neurons.

scientific article published in June 2010

Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf

scientific journal article

Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway

scientific article published on 12 August 2003

NRAS-driven melanoma: A RAF can hide another

scientific article published on 5 July 2017

NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma.

scientific article published in March 2018

Occurrence of alternatively spliced leader-delta onc-poly(A) transcripts in chicken neuroretina cells infected with Rous-associated virus type 1: implication in transduction of the c-mil/c-raf and c-Rmil/B-raf oncogenes

scientific article published on November 1993

PFKFB4 controls embryonic patterning via Akt signalling independently of glycolysis.

scientific article

Phosphorylation of MafA is essential for its transcriptional and biological properties

scientific article published in July 2001

Quail neuroretina c-Rmil(B-raf) proto-oncogene cDNAs encode two proteins of 93.5 and 95 kDa resulting from alternative splicing

scientific article published on July 1, 1992

RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.

scientific article

Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes

scientific article

Skin tumors induced by sorafenib; paradoxic RAS-RAF pathway activation and oncogenic mutations of HRAS, TP53, and TGFBR1

scientific article published on 17 November 2011

Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells

scientific journal article

The Raf/MEK/ERK pathway: new concepts of activation.

scientific article

The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression.

scientific article published on October 1995

The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells.

scientific article

Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways

scientific article

Translational control of tumor immune escape via the eIF4F-STAT1-PD-L1 axis in melanoma

scientific article published on 29 October 2018

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