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List of works by Pablo Escriba

2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy.

scientific article

2-hydroxy arachidonic acid: a new non-steroidal anti-inflammatory drug

scientific article (publication date: 2013)

2-hydroxyoleic acid affects cardiomyocyte [Ca2+]i transient and contractility in a region-dependent manner.

scientific article

A novel plasmid series for in vitro production of phoA translational fusions and its use in the construction of Escherichia coli PhoE::PhoA hybrid proteins

scientific article published on 01 December 1994

A scanning calorimetric study of natural DNA and antitumoral anthracycline antibiotic-DNA complexes.

scientific article published in January 1990

Age-dependent increases of immunoreactive imidazoline receptors in the human brain: possible association of a 29/30 kDa protein with the I2-imidazoline receptor identified by [3H]idazoxan

scientific article published on 01 January 1995

Alteration of lipids, G proteins, and PKC in cell membranes of elderly hypertensives.

scientific article

Analysis of the lipidome of xenografts using MALDI-IMS and UHPLC-ESI-QTOF.

scientific article

Antihypertensive action of 2-hydroxyoleic acid in SHRs via modulation of the protein kinase A pathway and Rho kinase

scientific article published on 10 May 2006

Changes in membrane organization upon spontaneous insertion of 2-hydroxylated unsaturated fatty acids in the lipid bilayer.

scientific article published on 17 February 2014

Chronic treatment with the monoamine oxidase inhibitors clorgyline and pargyline down-regulates non-adrenoceptor [3H]-idazoxan binding sites in the rat brain

scientific article published in March 1993

Cognitive recovery and restoration of cell proliferation in the dentate gyrus in the 5XFAD transgenic mice model of Alzheimer's disease following 2-hydroxy-DHA treatment

scientific article published on 10 October 2013

Corrigendum to "G protein-membrane interactions I: Gαi1 myristoyl and palmitoyl modifications in protein-lipid interactions and its implications in membrane microdomain localization" [Biochim. Biophys. Acta 1851/11 (2015) 1511-1520].

scientific article published on 10 November 2015

Decreased number and immunoreactivity of I2-imidazoline receptors in the frontal cortex of suicide victims

scientific article published on 01 July 1995

Density of guanine nucleotide-binding proteins in platelets of patients with major depression: increased abundance of the G alpha i2 subunit and down-regulation by antidepressant drug treatment.

scientific article published in October 1997

Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets.

scientific article

Disruption of cellular signaling pathways by daunomycin through destabilization of nonlamellar membrane structures ⬇️

scientific article published on August 1, 1995

Effects of 2-hydroxyoleic acid on the structural properties of biological and model plasma membranes

scientific article published on 01 January 2008

Effects of oleic acid and its congeners, elaidic and stearic acids, on the structural properties of phosphatidylethanolamine membranes.

scientific article published on 16 December 2002

Effects of the alkylating agent EEDQ on regulatory G proteins and recovery of agonist and antagonist alpha2-adrenoceptor binding sites in rat brain.

scientific article published in June 1998

Effects of unsaturated fatty acids and triacylglycerols on phosphatidylethanolamine membrane structure.

scientific article

Farnesol and geranylgeraniol modulate the structural properties of phosphatidylethanolamine model membranes.

scientific article

G protein-coupled receptor systems and their lipid environment in health disorders during aging.

scientific article published on 3 October 2006

G protein-membrane interactions I: Gαi1 myristoyl and palmitoyl modifications in protein-lipid interactions and its implications in membrane microdomain localization.

scientific article published on 4 August 2015

Identification of Biomarkers of Necrosis in Xenografts Using Imaging Mass Spectrometry.

scientific article published on 25 September 2015

Immunodetection of putative imidazoline receptor proteins in the human and rat brain and other tissues

scientific article published on 01 August 1994

Interaction of the C-terminal region of the Ggamma protein with model membranes.

scientific article published on June 2007

Interaction of transmembrane-spanning segments of the α2-adrenergic receptor with model membranes

scientific article published on 30 June 2009

LSL 60101, a selective ligand for imidazoline I2 receptors, on glial fibrillary acidic protein concentration

scientific article published on 01 July 1995

Lipid-protein interactions in GPCR-associated signaling.

scientific article published on 16 September 2006

Membrane Lipid Composition: Effect on Membrane and Organelle Structure, Function and Compartmentalization and Therapeutic Avenues. ⬇️

scientific article published in May 2019

Membrane lipid modifications and therapeutic effects mediated by hydroxydocosahexaenoic acid on Alzheimer's disease.

scientific article published on 27 December 2013

Membrane lipid therapy: Modulation of the cell membrane composition and structure as a molecular base for drug discovery and new disease treatment

scientific article published on 09 May 2015

Membrane structure and function: relevance of lipid and protein structures in cellular physiology, pathology and therapy

scientific article published in June 2014

Membrane-lipid therapy: a new approach in molecular medicine.

scientific article

Membranes: a meeting point for lipids, proteins and therapies

scientific article published on 08 February 2008

Minerval induces apoptosis in Jurkat and other cancer cells.

scientific article published on 24 December 2008

Molecular characterization and isolation of a 45-kilodalton imidazoline receptor protein from the rat brain

scientific article published on 01 September 1995

Oleic acid content is responsible for the reduction in blood pressure induced by olive oil

scientific article

Optimized Protocol To Analyze Changes in the Lipidome of Xenografts after Treatment with 2-Hydroxyoleic Acid

scientific article

Oral 2-hydroxyoleic acid inhibits reflex hypersensitivity and open-field-induced anxiety after spared nerve injury

scientific article published on 13 May 2014

Pharmacologic characterization of imidazoline receptor proteins identified by immunologic techniques and other methods.

scientific article

Pharmacological and immunological characterization of solubilized 130-140- and 66-kD imidazoline receptors in the rat brain.

scientific article

Regulation of the cancer cell membrane lipid composition by NaCHOleate: effects on cell signaling and therapeutical relevance in glioma.

scientific article published on 10 February 2014

Role of lipid polymorphism in G protein-membrane interactions: Nonlamellar-prone phospholipids and peripheral protein binding to membranes ⬇️

scientific article published on October 14, 1997

Role of the C-terminal basic amino acids and the lipid anchor of the Gγ2 protein in membrane interactions and cell localization

scientific article published on 21 February 2017

Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.

scientific article published on 21 November 2011

Structural basis of glycogen branching enzyme deficiency and pharmacologic rescue by rational peptide design

scientific journal article

Structure-effect relation of C18 long-chain fatty acids in the reduction of body weight in rats.

scientific article published on 4 December 2007

Sustained activation of sphingomyelin synthase by 2-hydroxyoleic acid induces sphingolipidosis in tumor cells.

scientific article published on 7 March 2013

The Implications for Cells of the Lipid Switches Driven by Protein-Membrane Interactions and the Development of Membrane Lipid Therapy

scientific article published on 27 March 2020

The Novel Anticancer Drug Hydroxytriolein Inhibits Lung Cancer Cell Proliferation via a Protein Kinase Cα- and Extracellular Signal-Regulated Kinase 1/2-Dependent Mechanism.

scientific article published on 11 June 2015

The effect of natural and synthetic fatty acids on membrane structure, microdomain organization, cellular functions and human health

scientific article published on 03 January 2014

The repression of E2F-1 is critical for the activity of Minerval against cancer.

scientific article published on 18 July 2005

The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid.

scientific article published on 27 January 2013

The significance of lipid composition for membrane activity: new concepts and ways of assessing function.

scientific article

The unfolded protein response in the therapeutic effect of hydroxy-DHA against Alzheimer's disease.

scientific article

Triacylglycerol mimetics regulate membrane interactions of glycogen branching enzyme: implications for therapy

scientific article published on 19 June 2017

Ultrastructural alterations in plasma membranes from drug-resistant P388 murine leukemia cells.

scientific article published in November 1990

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