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List of works by Massimo Valoti

2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta.

scientific article published in February 1999

3,5-di-t-butyl-4-hydroxyanisole (DTBHA) activation of rat skeletal muscle sarcoplasmic reticulum Ca(2+)-ATPase.

scientific article published in December 2001

A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-]Pyrimidine Dual Src/P-Glycoprotein Inhibitor

scientific article published on 19 June 2019

A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury ⬇️

scientific article published on August 27, 2012

Antioxidant properties of propargylamine derivatives: assessment of their ability to scavenge peroxynitrite

scientific article published on 01 April 2006

CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction.

scientific article

Cancer cell permeability-glycoprotein as a target of MDR reverters: possible role of novel dihydropyridine derivatives.

scientific article published on August 2006

Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injection of GABA, GABA(A) and GABA(B) agonists and antagonists.

scientific article published on 8 December 2003

Chemical Characterisation and Antihypertensive Effects of Locular Gel and Serum of Lycopersicum esculentum L. var. "Camone" Tomato in Spontaneously Hypertensive Rats

scientific article published on 18 August 2020

Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine.

scientific article

Cyclooxygenase activity of hemoglobin

scientific article published on 01 January 1994

Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl

scientific article published on 01 March 2000

DP7, a novel dihydropyridine multidrug resistance reverter, shows only weak inhibitory activity on human CYP3A enzyme(s).

scientific article published on 18 April 2009

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

scientific article

Distribution and peroxidative oxidation of 2-t-butyl-4-methoxyphenol in rat tissues after a single intraperitoneal dose

scientific article published on 01 January 1989

Effect of loxiglumide (CR 1505) on CCK-induced contractions and 3H-acetylcholine release from guinea-pig gallbladder.

scientific article published in November 1993

Effects of 2,5-di-t-butyl-1,4-benzohydroquinone (BHQ) on rat aorta smooth muscle ⬇️

scientific article published on April 10, 1998

Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics ⬇️

scientific article published on September 28, 2012

Effects of St John's wort and its active constituents, hypericin and hyperforin, on isolated rat urinary bladder

scientific article published on 09 July 2012

Effects of carnitine and its derivatives on gastric acid secretion in rats

scientific article published on 01 November 1996

Evidence of a coupled mechanism between monoamine oxidase and peroxidase in the metabolism of tyramine by rat intestinal mitochondria

article

Expression, microsomal and mitochondrial activities of cytochrome P450 enzymes in brain regions from control and phenobarbital-treated rabbits.

scientific article published on 16 November 2006

Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors.

scientific article published on 27 November 2017

Free radical intermediates during peroxidase oxidation of 2-t-butyl-4-methoxyphenol, 2,6-di-t-butyl-4-methylphenol, and related phenol compounds

scientific article published on 01 March 1989

Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds

scientific article published on 01 November 2006

GABA-mediated effects of some taurine derivatives injected i.c.v. on rabbit rectal temperature and gross motor behavior.

scientific article published on 4 April 2006

Gender-related neuronal and smooth muscle damage of guinea pig isolated urinary bladder from anoxia-glucopenia and reperfusion injury and its relationship to glycogen content.

scientific article published in January 2007

Gold Nanoparticles Uptake and Cytotoxicity Assessed on Rat Liver Precision-Cut Slices

scientific article published on 26 April 2012

Gold nanoparticles potentiate CaV channel currents in rat tail artery myocytes

scientific article published on 20 November 2017

HPLC determination of inorganic cation levels in CSF and plasma of conscious rabbits

scientific article published on 01 April 1993

Heteroaryl-substituted phenols as potential antioxidants

scientific article published on 01 June 2007

Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery

scientific article published on 22 February 2016

Interactions of 2,4,6-trinitrotoluene (TNT) with xenobiotic biotransformation system in European eel Anguilla anguilla (Linnaeus, 1758).

scientific article published on 14 April 2008

Interactions of Monoamine Oxidase Inhibitors, N-Acetylenic Analogues of Tryptamine, with Rat Liver Microsomal Cytochrome P450

scientific article published on 01 May 1994

Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses

scientific article published on 22 January 2016

Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach.

scientific article

Measurement of synthetic phenolic antioxidants in human tissues by high-performance liquid chromatography with coulometric electrochemical detection

scientific article published on 01 July 1997

Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents.

scientific article

Myorelaxant activity of 2-t-butyl-4-methoxyphenol (BHA) in guinea pig gastric fundus.

scientific article

N,N-bis(cyclohexanol)amine aryl esters inhibit P-glycoprotein as transport substrates.

scientific article published on 6 September 2011

Neuroprotection afforded by diazepam against oxygen/glucose deprivation-induced injury in rat cortical brain slices.

scientific article published on 19 January 2007

Neuroprotection afforded by some hindered phenols and alpha-tocopherol in guinea-pig detrusor strips subjected to anoxia-glucopenia and reperfusion-like conditions.

scientific article published in November 2001

On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings

scientific article published on 01 April 2000

Oxidative ring-coupling of tyrosine and its derivatives by purified rat intestinal peroxidase

scientific article published on 01 March 1992

Peroxidase catalysed formation of prostaglandins from arachidonic acid

scientific article published on 01 August 1989

Pharmacokinetics of chlorimipramine, chlorpromazine and their N-dealkylated metabolites in plasma of healthy volunteers after a single oral dose of the parent compounds

scientific article published on 01 September 1993

Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.

scientific article

Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage.

scientific article published on 18 August 2009

Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters

scientific article published on 18 April 2011

Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds

scientific article published on 01 September 1995

Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin.

scientific article published on May 1999

Red wine alcohol promotes quercetin absorption and directs its metabolism towards isorhamnetin and tamarixetin in rat intestine in vitro.

scientific article published in April 2006

Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases.

scientific article published in January 2010

Synthesis and in vitro pharmacological activity of oxypropanol analogs of labetalol.

scientific article

Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor.

scientific article published on 18 April 2013

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe

scientific article

Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage

scientific article published on 12 June 2011

The soy phytoestrogens genistein and daidzein as neuroprotective agents against anoxia-glucopenia and reperfusion damage in rat urinary bladder

scientific article published on 25 June 2012

Toxic injury to rat gut musculature following intraperitoneal administration of 2-t-butyl-4-methoxyphenol.

scientific article published on August 1993

Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol.

scientific article published on 18 January 2013

β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration

scientific article published on 31 May 2020

β-Naphtoflavone and Ethanol Induce Cytochrome P450 and Protect towards MPP⁺ Toxicity in Human Neuroblastoma SH-SY5Y Cells

article

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